Formulation and evaluation of carnosic acid nanoparticulate system for upregulation of neurotrophins in the brain upon intranasal administration

Journal of Drug Targeting

Volumn 21, Issue 1, 2013, Pages 44-53

  Vaka, Siva Ram Kiran ^a   Shivakumar, H N ^b   Repka, Michael A ^a   Murthy, S Narasimha ^a  

^a UNIVERSITY OF MISSISSIPPI   (United States)

^b A Constituent Unit of KLE Academy of Higher Education Research   (India)

Author keywords

Carnosic acid nanoparticles; Chitosan; Design of Experiments (DOE); Neurotrophins; Nose to brain

Indexed keywords

CARNOSIC ACID; CHITOSAN; NANOPARTICLE; NEUROTROPHIN; POLYPHOSPHATE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DRUG DELIVERY SYSTEM; DRUG EFFICACY; DRUG FORMULATION; GELATION; IN VITRO STUDY; IN VIVO STUDY; MALE; MUCOADHESION; NANOENCAPSULATION; NONHUMAN; OLFACTORY SYSTEM; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; ULTRASOUND; UPREGULATION;

ADMINISTRATION, INTRANASAL; ANIMALS; BRAIN; CHITOSAN; DITERPENES, ABIETANE; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG DELIVERY SYSTEMS; MALE; MODELS, THEORETICAL; NANOPARTICLES; NERVE GROWTH FACTORS; PARTICLE SIZE; PLANT EXTRACTS; POLYPHOSPHATES; RATS; RATS, SPRAGUE-DAWLEY; SONICATION; TIME FACTORS; UP-REGULATION;

EID: 84872008922     PISSN: 1061186X     EISSN: 10292330     Source Type: Journal    
DOI: 10.3109/1061186X.2012.725405     Document Type: Article

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