Preventive effect of 7,8-dihydroxyflavone against oxidative stress induced genotoxicity

Biological and Pharmaceutical Bulletin

Volumn 32, Issue 2, 2009, Pages 166-171

  Zhang, Rui ^a   Kang, Kyoung Ah ^a   Piao, Mei Jing ^a   Ko, Dong Ok ^a   Wang, Zhi Hong ^a   Chang, Weon Young ^a   You, Ho Jin ^b   Lee, In Kyung ^c   Kim, Bum Joon ^c   Kang, Sam Sik ^c   Hyun, Jin Won ^a  

^a Jeju National University   (South Korea)

^b Chosun University   (South Korea)

^c Seoul National University   (South Korea)

Author keywords

7,8 dihydroxyflavone; Apoptosis; DNA damage; Protein kinase B signal pathway; Reactive oxygen species

Indexed keywords

1,1 DIPHENYL 2 PICRYLHYDRAZYL; 2 MORPHOLINO 8 PHENYLCHROMONE; 7,8 DIHYDROXYFLAVONE; 8 HYDROXYDEOXYGUANOSINE; HISTONE H2AX; HYDROGEN PEROXIDE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; REACTIVE OXYGEN METABOLITE;

ANIMAL CELL; ANTIOXIDANT ACTIVITY; APOPTOSIS; ARTICLE; CELL POPULATION; CELL PROTECTION; COMET ASSAY; CONTROLLED STUDY; DNA DAMAGE; GENOTOXICITY; NONHUMAN; OXIDATIVE STRESS; PROTEIN EXPRESSION;

ANIMALS; BLOTTING, WESTERN; CELL DEATH; CELL LINE; COMET ASSAY; CRICETINAE; DEOXYGUANOSINE; DNA DAMAGE; DNA FRAGMENTATION; FIBROBLASTS; FLAVONES; FREE RADICAL SCAVENGERS; HYDROGEN PEROXIDE; IMMUNOHISTOCHEMISTRY; INDICATORS AND REAGENTS; MUTAGENS; ONCOGENE PROTEIN V-AKT; OXIDATIVE STRESS; PICRATES; REACTIVE OXYGEN SPECIES; SIGNAL TRANSDUCTION;

EID: 60749102990     PISSN: 09186158     EISSN: 13475215     Source Type: Journal    
DOI: 10.1248/bpb.32.166     Document Type: Article

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