Curcumin protects against thioacetamide-induced hepatic fibrosis by attenuating the inflammatory response and inducing apoptosis of damaged hepatocytes

Journal of Nutritional Biochemistry

Volumn 23, Issue 10, 2012, Pages 1352-1366

  Wang, Mu En ^a   Chen, Yi Chen ^a   Chen, I Shu ^b   Hsieh, Shu Chen ^a   Chen, Sheng Shih ^b   Chiu, Chih Hsien ^a  

^a NATIONAL TAIWAN UNIVERSITY   (Taiwan)

^b KAOHSIUNG VETERANS GENERAL HOSPITAL   (Taiwan)

Author keywords

Apoptosis; Curcumin; Hepatic fibrosis; Hepatocytes; Inflammation; Thioacetamide

Indexed keywords

CURCUMIN; MESSENGER RNA; PROTEIN BAX; PROTEIN BCL 2; PROTEIN P53; THIOACETAMIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; APOPTOSIS; ARTICLE; BAGG ALBINO MOUSE; CELL ACTIVATION; CONTROLLED STUDY; CYTOTOXICITY; DISEASE MODEL; DOWN REGULATION; FIBROGENESIS; HEPATITIS; IN VIVO STUDY; LIVER CELL; LIVER FIBROSIS; LIVER PROTECTION; MALE; MOUSE; NONHUMAN; NUCLEOTIDE SEQUENCE; PROTEIN EXPRESSION; STELLATE CELL; UPREGULATION;

ANIMALS; ANTINEOPLASTIC AGENTS; ANTIOXIDANTS; APOPTOSIS; BCL-2-ASSOCIATED X PROTEIN; CELL LINE; CELL PROLIFERATION; CURCUMIN; DNA DAMAGE; GENE EXPRESSION REGULATION; HEPATIC STELLATE CELLS; HEPATOCYTES; IN SITU NICK-END LABELING; INFLAMMATION; LIVER; LIVER CIRRHOSIS; MALE; MICE; MICE, INBRED BALB C; RNA, MESSENGER; THIOACETAMIDE; TUMOR SUPPRESSOR PROTEIN P53;

ANIMALIA; BACTERIA (MICROORGANISMS); MUS;

EID: 84865742981     PISSN: 09552863     EISSN: 18734847     Source Type: Journal    
DOI: 10.1016/j.jnutbio.2011.08.004     Document Type: Article

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