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Volumn 23, Issue 20, 2016, Pages 20205-20213

The effect of titanium dioxide nanoparticles on neuroinflammation response in rat brain

Author keywords

Astrocytes; Brain; Neurochemicals; Neuroinflammation; Rats; Titanium dioxide nanoparticles

Indexed keywords

BRAIN; CELLS AND CELL COMPONENTS; DOSE-RESPONSE RELATIONSHIP; GENE EXPRESSION; INORGANIC COMPOUND; NANOPARTICLE; NERVOUS SYSTEM DISORDER; NEUROLOGY; ORAL HEALTH; PROTEIN; RODENT; TOXIC SUBSTANCE;

EID: 84979235660     PISSN: 09441344     EISSN: 16147499     Source Type: Journal    
DOI: 10.1007/s11356-016-7234-8     Document Type: Article
Times cited : (57)

References (51)
  • 1
    • 84864457874 scopus 로고    scopus 로고
    • Cognitive impairment in rats induced by nano-CuO and its possible mechanisms
    • COI: 1:CAS:528:DC%2BC38Xht1SktbnO
    • An L, Liu S, Yang Z, Zhang T (2012) Cognitive impairment in rats induced by nano-CuO and its possible mechanisms. Toxicol Lett 213:220–227
    • (2012) Toxicol Lett , vol.213 , pp. 220-227
    • An, L.1    Liu, S.2    Yang, Z.3    Zhang, T.4
  • 2
    • 84894307748 scopus 로고    scopus 로고
    • Integrated analytical techniques with high sensitivity for studying brain translocation and potential impairment induced by intranasally instilled copper nanoparticles
    • COI: 1:CAS:528:DC%2BC2cXjsVKkurY%3D
    • Bai R, Zhang L, Liu Y, Li B, Wang L, Wang P, Autrup H, Beer C, Chen C (2014) Integrated analytical techniques with high sensitivity for studying brain translocation and potential impairment induced by intranasally instilled copper nanoparticles. Toxicol Lett 226:70–80
    • (2014) Toxicol Lett , vol.226 , pp. 70-80
    • Bai, R.1    Zhang, L.2    Liu, Y.3    Li, B.4    Wang, L.5    Wang, P.6    Autrup, H.7    Beer, C.8    Chen, C.9
  • 3
    • 84861191441 scopus 로고    scopus 로고
    • A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation
    • COI: 1:CAS:528:DC%2BC38XntlOhtro%3D
    • Banks CN, Lein PJ (2012) A review of experimental evidence linking neurotoxic organophosphorus compounds and inflammation. Neurotoxicology 33:575–584
    • (2012) Neurotoxicology , vol.33 , pp. 575-584
    • Banks, C.N.1    Lein, P.J.2
  • 4
    • 84881490316 scopus 로고    scopus 로고
    • A novel insight on chronic AlCl3 neurotoxicity through IL-6 and GFAP expressions: modulating effect of functional food fenugreek seeds
    • COI: 1:CAS:528:DC%2BC3sXht1ylsLnJ
    • Belaid-Nouira Y, Bakhta H, Samoud S, Trimech M, Haouas Z, Ben Cheikh H (2013) A novel insight on chronic AlCl3 neurotoxicity through IL-6 and GFAP expressions: modulating effect of functional food fenugreek seeds. Nutr Neurosci 16:218–224
    • (2013) Nutr Neurosci , vol.16 , pp. 218-224
    • Belaid-Nouira, Y.1    Bakhta, H.2    Samoud, S.3    Trimech, M.4    Haouas, Z.5    Ben Cheikh, H.6
  • 5
    • 0033953122 scopus 로고    scopus 로고
    • Glia maintain follower neuron survival during drosophila CNS development
    • COI: 1:CAS:528:DC%2BD3cXhsVOrtbw%3D
    • Booth GE, Kinrade EF, Hidalgo A (2000) Glia maintain follower neuron survival during drosophila CNS development. Development 127:237–244
    • (2000) Development , vol.127 , pp. 237-244
    • Booth, G.E.1    Kinrade, E.F.2    Hidalgo, A.3
  • 6
    • 0037066398 scopus 로고    scopus 로고
    • Pro-inflammatory effects of aluminum in human glioblastoma cells
    • COI: 1:CAS:528:DC%2BD38XisV2lsbw%3D
    • Campbell A, Yang EY, Tsai-Turton M, Bondy SC (2002) Pro-inflammatory effects of aluminum in human glioblastoma cells. Brain Res 933:60–65
    • (2002) Brain Res , vol.933 , pp. 60-65
    • Campbell, A.1    Yang, E.Y.2    Tsai-Turton, M.3    Bondy, S.C.4
  • 7
    • 84942509256 scopus 로고    scopus 로고
    • Effect of titanium dioxide nanoparticles on the cardiovascular system after oral administration
    • COI: 1:CAS:528:DC%2BC2MXhsFKnt73O
    • Chen Z, Wang Y, Zhuo L, Chen S, Zhao L, Luan X, Wang H, Jia G (2015) Effect of titanium dioxide nanoparticles on the cardiovascular system after oral administration. Toxicol Lett 239:123–130
    • (2015) Toxicol Lett , vol.239 , pp. 123-130
    • Chen, Z.1    Wang, Y.2    Zhuo, L.3    Chen, S.4    Zhao, L.5    Luan, X.6    Wang, H.7    Jia, G.8
  • 8
    • 84875296181 scopus 로고    scopus 로고
    • Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration
    • COI: 1:CAS:528:DC%2BC3sXns1Ors7s%3D
    • Cho WS, Kang BC, Lee JK, Jeong J, Che JH, Seok SH (2013) Comparative absorption, distribution, and excretion of titanium dioxide and zinc oxide nanoparticles after repeated oral administration. Part Fibre Toxicol 10:9
    • (2013) Part Fibre Toxicol , vol.10 , pp. 9
    • Cho, W.S.1    Kang, B.C.2    Lee, J.K.3    Jeong, J.4    Che, J.H.5    Seok, S.H.6
  • 10
    • 0035983277 scopus 로고    scopus 로고
    • Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia
    • Delgado M, Jonakait GM, Ganea D (2002) Vasoactive intestinal peptide and pituitary adenylate cyclase-activating polypeptide inhibit chemokine production in activated microglia. Glia 39:148–161
    • (2002) Glia , vol.39 , pp. 148-161
    • Delgado, M.1    Jonakait, G.M.2    Ganea, D.3
  • 12
    • 84940660873 scopus 로고    scopus 로고
    • Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat
    • Disdier C, Devoy J, Cosnefroy A, Chalansonnet M, Herlin-Boime N, Brun E, Lund A, Mabondzo A (2015) Tissue biodistribution of intravenously administrated titanium dioxide nanoparticles revealed blood-brain barrier clearance and brain inflammation in rat. Part Fibre Toxicol 12:27
    • (2015) Part Fibre Toxicol , vol.12 , pp. 27
    • Disdier, C.1    Devoy, J.2    Cosnefroy, A.3    Chalansonnet, M.4    Herlin-Boime, N.5    Brun, E.6    Lund, A.7    Mabondzo, A.8
  • 13
    • 80052088402 scopus 로고    scopus 로고
    • Applications of nanotechnology in food packaging and food safety: barrier materials, antimicrobials and sensors
    • COI: 1:CAS:528:DC%2BC3MXhtVygurfJ
    • Duncan TV (2011) Applications of nanotechnology in food packaging and food safety: barrier materials, antimicrobials and sensors. J Colloid Interface Sci 363:1–24
    • (2011) J Colloid Interface Sci , vol.363 , pp. 1-24
    • Duncan, T.V.1
  • 15
    • 33644811612 scopus 로고
    • A new and rapid colorimetric determination of acetylcholinesterase activity
    • COI: 1:CAS:528:DyaF3MXht1Gns7o%3D
    • Ellman GL, Courtney KD, Andres V Jr, Feather-Stone RM (1961) A new and rapid colorimetric determination of acetylcholinesterase activity. Biochem Pharmacol 7:88–95
    • (1961) Biochem Pharmacol , vol.7 , pp. 88-95
    • Ellman, G.L.1    Courtney, K.D.2    Andres, V.3    Feather-Stone, R.M.4
  • 16
    • 84856034604 scopus 로고    scopus 로고
    • Neuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrier
    • COI: 1:CAS:528:DC%2BC38XntlCqtw%3D%3D
    • Erickson MA, Dohi K, Banks WA (2012) Neuroinflammation: a common pathway in CNS diseases as mediated at the blood-brain barrier. Neuroimmunomodulation 19:121–130
    • (2012) Neuroimmunomodulation , vol.19 , pp. 121-130
    • Erickson, M.A.1    Dohi, K.2    Banks, W.A.3
  • 17
    • 84869857934 scopus 로고    scopus 로고
    • Interleukin-6, a major cytokine in the central nervous system
    • COI: 1:CAS:528:DC%2BC38Xhs1OitrnJ
    • Erta M, Quintana A, Hidalgo J (2012) Interleukin-6, a major cytokine in the central nervous system. Int J Biol Sci 8:1254–1266
    • (2012) Int J Biol Sci , vol.8 , pp. 1254-1266
    • Erta, M.1    Quintana, A.2    Hidalgo, J.3
  • 19
    • 57649121589 scopus 로고    scopus 로고
    • Modulation of neuritogenesis by astrocyte muscarinic receptors
    • COI: 1:CAS:528:DC%2BD1cXhtlCjsbjJ
    • Guizzetti M, Moore NH, Giordano G, Costa LG (2008) Modulation of neuritogenesis by astrocyte muscarinic receptors. J Biol Chem 283:31884–31897
    • (2008) J Biol Chem , vol.283 , pp. 31884-31897
    • Guizzetti, M.1    Moore, N.H.2    Giordano, G.3    Costa, L.G.4
  • 20
    • 84892956242 scopus 로고    scopus 로고
    • Cell-based in vitro blood-brain barrier model can rapidly evaluate nanoparticles’ brain permeability in association with particle size and surface modification
    • Hanada S, Fujioka K, Inoue Y, Kanaya F, Manome Y, Yamamoto K (2014) Cell-based in vitro blood-brain barrier model can rapidly evaluate nanoparticles’ brain permeability in association with particle size and surface modification. Int J Mol Sci 15:1812–1825
    • (2014) Int J Mol Sci , vol.15 , pp. 1812-1825
    • Hanada, S.1    Fujioka, K.2    Inoue, Y.3    Kanaya, F.4    Manome, Y.5    Yamamoto, K.6
  • 21
    • 77956012861 scopus 로고    scopus 로고
    • Neurotoxicological effects and the impairment of spatial recognition memory in mice caused by exposure to TiO2 nanoparticles
    • COI: 1:CAS:528:DC%2BC3cXhtVyit77O
    • Hu R, Gong X, Duan Y, Li N, Che Y, Cui Y, Zhou M, Liu C, Wang H, Hong F (2010) Neurotoxicological effects and the impairment of spatial recognition memory in mice caused by exposure to TiO2 nanoparticles. Biomaterials 31:8043–8050
    • (2010) Biomaterials , vol.31 , pp. 8043-8050
    • Hu, R.1    Gong, X.2    Duan, Y.3    Li, N.4    Che, Y.5    Cui, Y.6    Zhou, M.7    Liu, C.8    Wang, H.9    Hong, F.10
  • 22
    • 79957680045 scopus 로고    scopus 로고
    • Molecular mechanism of hippocampal apoptosis of mice following exposure to titanium dioxide nanoparticles
    • COI: 1:CAS:528:DC%2BC3MXmvFOltb0%3D
    • Hu R, Zheng L, Zhang T, Gao G, Cui Y, Cheng Z, Cheng J, Hong M, Tang M, Hong F (2011) Molecular mechanism of hippocampal apoptosis of mice following exposure to titanium dioxide nanoparticles. J Hazard Mater 191:32–40
    • (2011) J Hazard Mater , vol.191 , pp. 32-40
    • Hu, R.1    Zheng, L.2    Zhang, T.3    Gao, G.4    Cui, Y.5    Cheng, Z.6    Cheng, J.7    Hong, M.8    Tang, M.9    Hong, F.10
  • 23
    • 0034054736 scopus 로고    scopus 로고
    • Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley neuropathology consortium
    • COI: 1:CAS:528:DC%2BD3cXlslartrg%3D
    • Johnston-Wilson NL, Sims CD, Hofmann JP, Anderson L, Shore AD, Torrey EF, Yolken RH (2000) Disease-specific alterations in frontal cortex brain proteins in schizophrenia, bipolar disorder, and major depressive disorder. The Stanley neuropathology consortium. Mol Psychiatry 5:142–149
    • (2000) Mol Psychiatry , vol.5 , pp. 142-149
    • Johnston-Wilson, N.L.1    Sims, C.D.2    Hofmann, J.P.3    Anderson, L.4    Shore, A.D.5    Torrey, E.F.6    Yolken, R.H.7
  • 24
    • 25444495866 scopus 로고    scopus 로고
    • Microglia in health and disease
    • COI: 1:CAS:528:DC%2BD2MXnsVelt7g%3D
    • Kim SU, de Vellis J (2005) Microglia in health and disease. J Neurosci Res 81:302–313
    • (2005) J Neurosci Res , vol.81 , pp. 302-313
    • Kim, S.U.1    de Vellis, J.2
  • 25
    • 84934270686 scopus 로고    scopus 로고
    • Hazard effects of nanoparticles in central nervous system: searching for biocompatible nanomaterials for drug delivery
    • COI: 1:CAS:528:DC%2BC2MXhtVyiu7fP
    • Leite PE, Pereira MR, Granjeiro JM (2015) Hazard effects of nanoparticles in central nervous system: searching for biocompatible nanomaterials for drug delivery. Toxicol in Vitro 29:1653–1660
    • (2015) Toxicol in Vitro , vol.29 , pp. 1653-1660
    • Leite, P.E.1    Pereira, M.R.2    Granjeiro, J.M.3
  • 27
    • 70350624697 scopus 로고    scopus 로고
    • Oxidative stress in the brain of mice caused by translocated nanoparticulate TiO2 delivered to the abdominal cavity
    • COI: 1:CAS:528:DC%2BD1MXhtleksbjE
    • Ma L, Liu J, Li N, Wang J, Duan Y, Yan J, Liu H, Wang H, Hong F (2010) Oxidative stress in the brain of mice caused by translocated nanoparticulate TiO2 delivered to the abdominal cavity. Biomaterials 31:99–105
    • (2010) Biomaterials , vol.31 , pp. 99-105
    • Ma, L.1    Liu, J.2    Li, N.3    Wang, J.4    Duan, Y.5    Yan, J.6    Liu, H.7    Wang, H.8    Hong, F.9
  • 31
    • 84884246344 scopus 로고    scopus 로고
    • Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain
    • Ramesh G, MacLean AG, Philipp MT (2013) Cytokines and chemokines at the crossroads of neuroinflammation, neurodegeneration, and neuropathic pain. Mediat Inflamm 2013:480739
    • (2013) Mediat Inflamm , vol.2013 , pp. 480739
    • Ramesh, G.1    MacLean, A.G.2    Philipp, M.T.3
  • 33
    • 3042673717 scopus 로고    scopus 로고
    • Expression and localization of acetylcholinesterase at the neuromuscular junction
    • COI: 1:CAS:528:DC%2BD2cXitlGksb4%3D
    • Rotundo RL (2003) Expression and localization of acetylcholinesterase at the neuromuscular junction. J Neurocytol 32:743–766
    • (2003) J Neurocytol , vol.32 , pp. 743-766
    • Rotundo, R.L.1
  • 34
    • 84876113687 scopus 로고    scopus 로고
    • Titanium dioxide nanoparticles: a review of current toxicological data
    • Shi H, Magaye R, Castranova V, Zhao J (2013) Titanium dioxide nanoparticles: a review of current toxicological data. Part Fibre Toxicol 10
    • (2013) Part Fibre Toxicol , pp. 10
    • Shi, H.1    Magaye, R.2    Castranova, V.3    Zhao, J.4
  • 35
    • 71549145597 scopus 로고    scopus 로고
    • Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse
    • COI: 1:CAS:528:DC%2BD1MXhsFGhtbbF
    • Shin JA, Lee EJ, Seo SM, Kim HS, Kang JL, Park EM (2010) Nanosized titanium dioxide enhanced inflammatory responses in the septic brain of mouse. Neuroscience 165:445–454
    • (2010) Neuroscience , vol.165 , pp. 445-454
    • Shin, J.A.1    Lee, E.J.2    Seo, S.M.3    Kim, H.S.4    Kang, J.L.5    Park, E.M.6
  • 36
    • 84923011007 scopus 로고    scopus 로고
    • Synaptic degeneration in rat brain after prolonged oral exposure to silver nanoparticles
    • COI: 1:CAS:528:DC%2BC2cXhvFCnt77P
    • Skalska J, Frontczak-Baniewicz M, Strużyńska L (2015) Synaptic degeneration in rat brain after prolonged oral exposure to silver nanoparticles. Neurotoxicology 46:145–154
    • (2015) Neurotoxicology , vol.46 , pp. 145-154
    • Skalska, J.1    Frontczak-Baniewicz, M.2    Strużyńska, L.3
  • 37
    • 84940107431 scopus 로고    scopus 로고
    • A review on potential neurotoxicity of titanium dioxide nanoparticles
    • Song B, Liu J, Feng X, Wei L, Shao L (2015) A review on potential neurotoxicity of titanium dioxide nanoparticles. Nanoscale Res Lett 10:1042
    • (2015) Nanoscale Res Lett , vol.10 , pp. 1042
    • Song, B.1    Liu, J.2    Feng, X.3    Wei, L.4    Shao, L.5
  • 38
    • 84994048626 scopus 로고    scopus 로고
    • Unraveling the neurotoxicity of titanium dioxide nanoparticles: focusing on molecular mechanisms Beilstein J
    • Song B, Zhang Y, Liu J, Feng X, Zhou T, Shao L (2016) Unraveling the neurotoxicity of titanium dioxide nanoparticles: focusing on molecular mechanisms Beilstein J. Nanotechnology 7:645–654
    • (2016) Nanotechnology , vol.7 , pp. 645-654
    • Song, B.1    Zhang, Y.2    Liu, J.3    Feng, X.4    Zhou, T.5    Shao, L.6
  • 41
    • 39049137363 scopus 로고    scopus 로고
    • Inhibitory effect of some natural and semisynthetic phenolic lipids upon acetylcholinesterase activity
    • COI: 1:CAS:528:DC%2BD1cXhs1Oktr8%3D
    • Stasiuk M, Bartosiewicz D, Kozubek A (2008) Inhibitory effect of some natural and semisynthetic phenolic lipids upon acetylcholinesterase activity. Food Chem 108:996–1001
    • (2008) Food Chem , vol.108 , pp. 996-1001
    • Stasiuk, M.1    Bartosiewicz, D.2    Kozubek, A.3
  • 42
    • 3342929297 scopus 로고    scopus 로고
    • Beta-naphthoflavone disturbs astrocytic differentiation of C6 glioma cells by inhibiting autocrine interleukin-6
    • COI: 1:CAS:528:DC%2BD2cXmsFert7s%3D
    • Takanaga H, Yoshitake T, Yatabe E, Hara S, Kunimoto M (2004) Beta-naphthoflavone disturbs astrocytic differentiation of C6 glioma cells by inhibiting autocrine interleukin-6. J Neurochem 90:750–757
    • (2004) J Neurochem , vol.90 , pp. 750-757
    • Takanaga, H.1    Yoshitake, T.2    Yatabe, E.3    Hara, S.4    Kunimoto, M.5
  • 44
    • 56549115351 scopus 로고    scopus 로고
    • Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases
    • COI: 1:CAS:528:DC%2BD1cXhsVCmsb7I
    • Wang J, Chen C, Liu Y, Jiao F, Li W, Lao F, Li Y, Li B, Ge C, Zhou G, Gao Y, Zhao Y, Chai Z (2008a) Potential neurological lesion after nasal instillation of TiO2 nanoparticles in the anatase and rutile crystal phases. Toxicol Lett 183:72–80
    • (2008) Toxicol Lett , vol.183 , pp. 72-80
    • Wang, J.1    Chen, C.2    Liu, Y.3    Jiao, F.4    Li, W.5    Lao, F.6    Li, Y.7    Li, B.8    Ge, C.9    Zhou, G.10    Gao, Y.11    Zhao, Y.12    Chai, Z.13
  • 45
    • 56049102066 scopus 로고    scopus 로고
    • Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles
    • COI: 1:CAS:528:DC%2BD1cXhsVWmt7fF
    • Wang J, Liu Y, Jiao F, Lao F, Li W, Gu Y, Li Y, Ge C, Zhou G, Li B, Zhao Y, Chai Z, Chen C (2008b) Time-dependent translocation and potential impairment on central nervous system by intranasally instilled TiO(2) nanoparticles. Toxicology 254:82–90
    • (2008) Toxicology , vol.254 , pp. 82-90
    • Wang, J.1    Liu, Y.2    Jiao, F.3    Lao, F.4    Li, W.5    Gu, Y.6    Li, Y.7    Ge, C.8    Zhou, G.9    Li, B.10    Zhao, Y.11    Chai, Z.12    Chen, C.13
  • 46
    • 69249213929 scopus 로고    scopus 로고
    • Adsorption and inhibition of acetylcholinesterase by different nanoparticles
    • COI: 1:CAS:528:DC%2BD1MXhtVOisbjK
    • Wang Z, Zhao J, Li F, Gao D, Xing B (2009) Adsorption and inhibition of acetylcholinesterase by different nanoparticles. Chemosphere 77:67–73
    • (2009) Chemosphere , vol.77 , pp. 67-73
    • Wang, Z.1    Zhao, J.2    Li, F.3    Gao, D.4    Xing, B.5
  • 47
    • 0036381465 scopus 로고    scopus 로고
    • Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates
    • COI: 1:CAS:528:DC%2BD38XntFensLs%3D
    • Worek F, Reiter G, Eyer P, Szinicz L (2002) Reactivation kinetics of acetylcholinesterase from different species inhibited by highly toxic organophosphates. Arch Toxicol 76:523–529
    • (2002) Arch Toxicol , vol.76 , pp. 523-529
    • Worek, F.1    Reiter, G.2    Eyer, P.3    Szinicz, L.4
  • 48
    • 84872675495 scopus 로고    scopus 로고
    • Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus
    • COI: 1:CAS:528:DC%2BC3sXhs1eqt7o%3D
    • Wu J, Ding T, Sun J (2013) Neurotoxic potential of iron oxide nanoparticles in the rat brain striatum and hippocampus. Neurotoxicology 34:243–253
    • (2013) Neurotoxicology , vol.34 , pp. 243-253
    • Wu, J.1    Ding, T.2    Sun, J.3
  • 49
    • 84866292862 scopus 로고    scopus 로고
    • Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro
    • COI: 1:CAS:528:DC%2BC38XhsVemt7%2FI
    • Xue Y, Wu J, Sun J (2012) Four types of inorganic nanoparticles stimulate the inflammatory reaction in brain microglia and damage neurons in vitro. Toxicol Lett 214:91–98
    • (2012) Toxicol Lett , vol.214 , pp. 91-98
    • Xue, Y.1    Wu, J.2    Sun, J.3
  • 50
    • 77649225653 scopus 로고    scopus 로고
    • The blood brain barrier and the role of cytokines in neuropsychiatry
    • Yarlagadda A, Alfson E, Clayton AH (2009) The blood brain barrier and the role of cytokines in neuropsychiatry. Psychiatry (Edgmont) 6:18–22
    • (2009) Psychiatry (Edgmont) , vol.6 , pp. 18-22
    • Yarlagadda, A.1    Alfson, E.2    Clayton, A.H.3


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