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Volumn 2, Issue , 2015, Pages

Epigenetic mechanisms leading to overexpression of HMGA proteins in human pituitary adenomas

Author keywords

HMGA proteins; Long non coding rna; MicroRNAs; Pituitary tumors; Pseudogenes

Indexed keywords


EID: 84979030750     PISSN: 20950217     EISSN: 20950225     Source Type: Journal    
DOI: 10.3389/fmed.2015.00039     Document Type: Article
Times cited : (34)

References (54)
  • 2
    • 84891816591 scopus 로고    scopus 로고
    • Advances in understanding pituitary tumors
    • Kopczak A, Renner U, Karl Stalla G. Advances in understanding pituitary tumors. FlOOOPrime Rep (2014) 6:5. doi:10.12703/P6-5
    • (2014) Floooprime Rep , vol.6 , pp. 5
    • Kopczak, A.1    Renner, U.2    Karl Stalla, G.3
  • 3
    • 84903581309 scopus 로고    scopus 로고
    • In search of a prognostic classification of endocrine pituitary tumors
    • Trouillas J. In search of a prognostic classification of endocrine pituitary tumors. Endocr Pathol (2014) 25:124-32. doi:10.1007/sl2022-014-9322-y
    • (2014) Endocr Pathol , vol.25 , pp. 124-132
    • Trouillas, J.1
  • 4
    • 79955093923 scopus 로고    scopus 로고
    • Pathogenesis of pituitary tumors
    • Melmed S. Pathogenesis of pituitary tumors. Nat Rev Endocrinol (2011) 7:257-66. doi:10.1038/nrendo.2011.40
    • (2011) Nat Rev Endocrinol , vol.7 , pp. 257-266
    • Melmed, S.1
  • 6
    • 0030910680 scopus 로고    scopus 로고
    • Isolation and characterization of a pituitary tumor- transforming gene (PTTG)
    • Pei L, Melmed S. Isolation and characterization of a pituitary tumor- transforming gene (PTTG). Mol Endocrinol (1997) 11:433-41. doi:10.1210/mend.11.4.9911
    • (1997) Mol Endocrinol , vol.11 , pp. 433-441
    • Pei, L.1    Melmed, S.2
  • 7
    • 4043059447 scopus 로고    scopus 로고
    • Pituitary tumor transforming gene: An update
    • Yu R, Melmed S. Pituitary tumor transforming gene: an update. Front Hortn Res (2004) 32:175-85.
    • (2004) Front Hortn Res , vol.32 , pp. 175-185
    • Yu, R.1    Melmed, S.2
  • 8
    • 0036959841 scopus 로고    scopus 로고
    • Loss of expression of GADD45 gamma, a growth inhibitory gene, in human pituitary adenomas: Implications for tumorigenesis
    • Zhang X, Sun H, Danila DC, Johnson SR, Zhou Y, Swearingen B, et al. Loss of expression of GADD45 gamma, a growth inhibitory gene, in human pituitary adenomas: implications for tumorigenesis. J Clin Endocrinol Metab (2002) 87:1262-7. doi:10.1210/jc.87.3.1262
    • (2002) J Clin Endocrinol Metab , vol.87 , pp. 1262-1267
    • Zhang, X.1    Sun, H.2    Danila, D.C.3    Johnson, S.R.4    Zhou, Y.5    Swearingen, B.6
  • 9
    • 64149113840 scopus 로고    scopus 로고
    • Cell cycle control of pituitary development and disease
    • Quereda V, Malumbres M. Cell cycle control of pituitary development and disease, J Mol Endocrinol (2009) 42:75-86. doi:10.1677/JME-08-0146
    • (2009) J Mol Endocrinol , vol.42 , pp. 75-86
    • Quereda, V.1    Malumbres, M.2
  • 11
    • 15844384256 scopus 로고    scopus 로고
    • A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kipl-deficient mice
    • Fero ML, Rivkin M, Tasch M, Porter P, Carow CE, Firpo E, et al. A syndrome of multiorgan hyperplasia with features of gigantism, tumorigenesis, and female sterility in p27Kipl-deficient mice. Cell (1996) 85:733-44. doi:10.1016/S0092-8674(00)81239-8
    • (1996) Cell , vol.85 , pp. 733-744
    • Fero, M.L.1    Rivkin, M.2    Tasch, M.3    Porter, P.4    Carow, C.E.5    Firpo, E.6
  • 12
    • 0032530112 scopus 로고    scopus 로고
    • CDK inhibitors pl8(INK4c) and p27(Kipl) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis
    • Franklin DS, Godfrey VL, Lee H, Kovalev GI, Schoonhoven R, Chen-Kiang S, et al. CDK inhibitors pl8(INK4c) and p27(Kipl) mediate two separate pathways to collaboratively suppress pituitary tumorigenesis. Genes Dev (1998) 12:2899-911. doi:10.1101/gad.12.18.2899
    • (1998) Genes Dev , vol.12 , pp. 2899-2911
    • Franklin, D.S.1    Godfrey, V.L.2    Lee, H.3    Kovalev, G.I.4    Schoonhoven, R.5    Chen-Kiang, S.6
  • 14
    • 84924508821 scopus 로고    scopus 로고
    • Recurrent gain- of-function USP8 mutations in Cushing’s disease
    • Ma Z-Y, Song Z-J, Chen J-H, Wang Y-F, Li S-Q, Zhou L-F, et al. Recurrent gain- of-function USP8 mutations in Cushing’s disease. Cell Res (2015) 25(3):306-17. doi:10.1038/cr.2015.20
    • (2015) Cell Res , vol.25 , Issue.3 , pp. 306-317
    • Ma, Z.-Y.1    Song, Z.-J.2    Chen, J.-H.3    Wang, Y.-F.4    Li, S.-Q.5    Zhou, L.-F.6
  • 15
    • 0025196283 scopus 로고
    • The A.T-DNA-binding domain of mammalian high mobility group I chromosomal proteins. A novel peptide motif for recognizing DNA structure
    • Reeves R, Nissen MS. The A.T-DNA-binding domain of mammalian high mobility group I chromosomal proteins. A novel peptide motif for recognizing DNA structure. J Biol Chem (1990) 265:8573-82.
    • (1990) J Biol Chem , vol.265 , pp. 8573-8582
    • Reeves, R.1    Nissen, M.S.2
  • 16
    • 0029094903 scopus 로고
    • Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression
    • Abdulkadir SA, Krishna S, Thanos D, Maniatis T, Strominger JL, Ono SJ. Functional roles of the transcription factor Oct-2A and the high mobility group protein I/Y in HLA-DRA gene expression. J Exp Med (1995) 182:487-500. doi:10.1084/jem.182.2.487
    • (1995) J Exp Med , vol.182 , pp. 487-500
    • Abdulkadir, S.A.1    Krishna, S.2    Thanos, D.3    Maniatis, T.4    Strominger, J.L.5    Ono, S.J.6
  • 17
    • 0028142679 scopus 로고
    • An HMG- like protein that can switch a transcriptional activator to a repressor
    • Lehming N, Thanos D, Brickman JM, Ma J, Maniatis T, Ptashne M. An HMG- like protein that can switch a transcriptional activator to a repressor. Nature (1994) 371:175-9. doi:10.1038/371175a0
    • (1994) Nature , vol.371 , pp. 175-179
    • Lehming, N.1    Thanos, D.2    Brickman, J.M.3    Ma, J.4    Maniatis, T.5    Ptashne, M.6
  • 18
    • 0027893397 scopus 로고
    • The high mobility group protein HMG I(Y) is an essential structural component of a virus-inducible enhancer complex
    • Thanos D, Du W, Maniatis T. The high mobility group protein HMG I(Y) is an essential structural component of a virus-inducible enhancer complex. Cold Spring Harb Symp Quant Biol (1993) 58:73-81. doi:10.1101/SQB.1993.058.01.011
    • (1993) Cold Spring Harb Symp Quant Biol , vol.58 , pp. 73-81
    • Thanos, D.1    Du, W.2    Maniatis, T.3
  • 19
    • 74849129422 scopus 로고    scopus 로고
    • HMG A and cancer
    • Fedele M, Fusco A. HMG A and cancer. Biochim Biophys Acta (2010) 1799:48-54. doi:10.1016/j.bbagrm.2009.11.007
    • (2010) Biochim Biophys Acta , vol.1799 , pp. 48-54
    • Fedele, M.1    Fusco, A.2
  • 20
    • 0028860339 scopus 로고
    • Inhibition of HMGI-C protein synthesis suppresses retrovirally induced neoplastic transformation of rat thyroid cells
    • Berlingieri MT, Manfioletti G, Santoro M, Bandiera A, Visconti R, Gian- cotti V, et al. Inhibition of HMGI-C protein synthesis suppresses retrovirally induced neoplastic transformation of rat thyroid cells. Mol Cell Biol (1995) 15: 1545-53.
    • (1995) Mol Cell Biol , vol.15 , pp. 1545-1553
    • Berlingieri, M.T.1    Manfioletti, G.2    Santoro, M.3    Bandiera, A.4    Visconti, R.5    Gian-Cotti, V.6
  • 21
    • 0033881018 scopus 로고    scopus 로고
    • The oncogenic properties of the HMG-I gene family the oncogenic properties of the HMG-I gene family 1
    • Wood LJ, Maher JF, Bunton TE, Resar LMS. The oncogenic properties of the HMG-I gene family the oncogenic properties of the HMG-I gene family 1. Cancer Res (2000) 60(15):4256-61.
    • (2000) Cancer Res , vol.60 , Issue.15 , pp. 4256-4261
    • Wood, L.J.1    Maher, J.F.2    Bunton, T.E.3    Resar, L.M.S.4
  • 22
    • 0034933837 scopus 로고    scopus 로고
    • Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL- 15 pathway
    • Baldassarre G, Fedele M, Battista S, Vecchione A, Klein-Szanto AJ, Santoro M, et al. Onset of natural killer cell lymphomas in transgenic mice carrying a truncated HMGI-C gene by the chronic stimulation of the IL-2 and IL- 15 pathway. Proc Natl Acad Sci USA (2001) 98:7970-5. doi:10.1073/pnas.141224998
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 7970-7975
    • Baldassarre, G.1    Fedele, M.2    Battista, S.3    Vecchione, A.4    Klein-Szanto, A.J.5    Santoro, M.6
  • 23
    • 85047700396 scopus 로고    scopus 로고
    • Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas
    • Fedele M, Battista S, Kenyon L, Baldassarre G, Fidanza V, Klein-Szanto AJP, et al. Overexpression of the HMGA2 gene in transgenic mice leads to the onset of pituitary adenomas. Oncogene (2002) 21:3190-8. doi:10.1038/sj.onc.1205428
    • (2002) Oncogene , vol.21 , pp. 3190-3198
    • Fedele, M.1    Battista, S.2    Kenyon, L.3    Baldassarre, G.4    Fidanza, V.5    Klein-Szanto, A.6
  • 24
    • 19944420447 scopus 로고    scopus 로고
    • Transgenic mice overexpressing the wild-type form of the HMGAl gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas
    • Fedele M, Pentimalli F, Baldassarre G, Battista S, Klein-Szanto AJP, Kenyon L, et al. Transgenic mice overexpressing the wild-type form of the HMGAl gene develop mixed growth hormone/prolactin cell pituitary adenomas and natural killer cell lymphomas. Oncogene (2005) 24:3427-35. doi:10.1038/sj.onc.1208501
    • (2005) Oncogene , vol.24 , pp. 3427-3435
    • Fedele, M.1    Pentimalli, F.2    Baldassarre, G.3    Battista, S.4    Klein-Szanto, A.5    Kenyon, L.6
  • 25
    • 0029018303 scopus 로고
    • Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains
    • Ashar HR, Fejzo MS, Tkachenko A, Zhou X, Fletcher JA, Weremowicz S, et al. Disruption of the architectural factor HMGI-C: DNA-binding AT hook motifs fused in lipomas to distinct transcriptional regulatory domains. Cell (1995) 82:57-65. doi:10.1016/0092-8674(95)90052-7
    • (1995) Cell , vol.82 , pp. 57-65
    • Ashar, H.R.1    Fejzo, M.S.2    Tkachenko, A.3    Zhou, X.4    Fletcher, J.A.5    Weremowicz, S.6
  • 26
    • 0029088063 scopus 로고
    • Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours
    • Schoenmakers EF, Wanschura S, Mols R, Bullerdiek J, Van den Berghe H, Van de Ven WJ. Recurrent rearrangements in the high mobility group protein gene, HMGI-C, in benign mesenchymal tumours. Nat Genet (1995) 10:436-44. doi:10.1038/ng0895-436
    • (1995) Nat Genet , vol.10 , pp. 436-444
    • Schoenmakers, E.F.1    Wanschura, S.2    Mols, R.3    Bullerdiek, J.4    Van den Berghe, H.5    Van de Ven, W.J.6
  • 27
    • 0037089558 scopus 로고    scopus 로고
    • The high mobility group A2 gene is amplified and overexpressed in human prolactinomas
    • Finelli P, Pierantoni GM, Giardino D, Losa M, Rodeschini O, Fedele M, et al. The high mobility group A2 gene is amplified and overexpressed in human prolactinomas. Cancer Res (2002) 62:2398-405.
    • (2002) Cancer Res , vol.62 , pp. 2398-2405
    • Finelli, P.1    Pierantoni, G.M.2    Giardino, D.3    Losa, M.4    Rodeschini, O.5    Fedele, M.6
  • 28
    • 29144439963 scopus 로고    scopus 로고
    • High-mobility group A2 gene expression is frequently induced in non-functioning pituitary adenomas (NFPAs), even in the absence of chromosome 12 polysomy
    • Pierantoni GM, Finelli P, Valtorta E, Giardino D, Rodeschini O, Esposito F, et al. High-mobility group A2 gene expression is frequently induced in non-functioning pituitary adenomas (NFPAs), even in the absence of chromosome 12 polysomy. Endocr Relat Cancer (2005) 12:867-74. doi:10.1677/erc.l.01049
    • (2005) Endocr Relat Cancer , vol.12 , pp. 867-874
    • Pierantoni, G.M.1    Finelli, P.2    Valtorta, E.3    Giardino, D.4    Rodeschini, O.5    Esposito, F.6
  • 29
    • 47249156807 scopus 로고    scopus 로고
    • Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses
    • Evans C-O, Moreno CS, Zhan X, McCabe MT, Vertino PM, Desiderio DM, et al. Molecular pathogenesis of human prolactinomas identified by gene expression profiling, RT-qPCR, and proteomic analyses. Pituitary (2008) 11:231-45. doi:10.1007/s11102-007-0082-2
    • (2008) Pituitary , vol.11 , pp. 231-245
    • Evans, C.-O.1    Moreno, C.S.2    Zhan, X.3    McCabe, M.T.4    Vertino, P.M.5    Desiderio, D.M.6
  • 30
    • 62449278948 scopus 로고    scopus 로고
    • HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas
    • De Martino I, Visone R, Wierinckx A, Palmieri D, Ferraro A, Cappabianca P, et al. HMGA proteins up-regulate CCNB2 gene in mouse and human pituitary adenomas. Cancer Res (2009) 69:1844-50. doi:10.1158/0008-5472.CAN-08-4133
    • (2009) Cancer Res , vol.69 , pp. 1844-1850
    • De Martino, I.1    Visone, R.2    Wierinckx, A.3    Palmieri, D.4    Ferraro, A.5    Cappabianca, P.6
  • 31
    • 84894560725 scopus 로고    scopus 로고
    • Nonfunctioning pituitary adenomas: Association of Ki-67 and HMGA-1 labeling indices with residual tumor growth
    • Šteno A, Bocko J, Rychlý B, Chorváth M, Celec P, Fabian M, et al. Nonfunctioning pituitary adenomas: association of Ki-67 and HMGA-1 labeling indices with residual tumor growth. Acta Neurochir (Wien) (2014) 156:451-61. doi:10.1007/S00701-014-1993-0
    • (2014) Acta Neurochir (Wien) , vol.156 , pp. 451-461
    • Šteno, A.1    Bocko, J.2    Rychlý, B.3    Chorváth, M.4    Celec, P.5    Fabian, M.6
  • 33
    • 0030863948 scopus 로고    scopus 로고
    • Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product
    • Vallone D, Battista S, Pierantoni GM, Fedele M, Casalino L, Santoro M, et al. Neoplastic transformation of rat thyroid cells requires the junB and fra-1 gene induction which is dependent on the HMGI-C gene product. EMBO f (1997) 16:5310-21. doi:10.1093/emboj/16.17.5310
    • (1997) EMBO F , vol.16 , pp. 5310-5321
    • Vallone, D.1    Battista, S.2    Pierantoni, G.M.3    Fedele, M.4    Casalino, L.5    Santoro, M.6
  • 35
    • 77955336023 scopus 로고    scopus 로고
    • HMGA2: A pituitary tumour subtype- specific oncogene?
    • Fedele M, Palmieri D, Fusco A. HMGA2: a pituitary tumour subtype- specific oncogene? Mol Cell Endocrinol (2010) 326:19-24. doi:10.1016/j.mce.2010.03.019
    • (2010) Mol Cell Endocrinol , vol.326 , pp. 19-24
    • Fedele, M.1    Palmieri, D.2    Fusco, A.3
  • 36
    • 77949614316 scopus 로고    scopus 로고
    • Increased expression of HMGAl correlates with tumour invasiveness and proliferation in human pituitary adenomas
    • Wang EL, Qian ZR, Rahman MM, Yoshimoto K, Yamada S, Kudo E, et al. Increased expression of HMGAl correlates with tumour invasiveness and proliferation in human pituitary adenomas. Histopathology (2010) 56:501-9. doi:10.1111/j.l365-2559.2010.03495.x
    • (2010) Histopathology , vol.56 , pp. 501-509
    • Wang, E.L.1    Qian, Z.R.2    Rahman, M.M.3    Yoshimoto, K.4    Yamada, S.5    Kudo, E.6
  • 37
    • 13144295005 scopus 로고    scopus 로고
    • Conserved non-genic sequences - An unexpected feature of mammalian genomes
    • Dermitzakis ET, Reymond A, Antonarakis SE. Conserved non-genic sequences - an unexpected feature of mammalian genomes. Nat Rev Genet (2005) 6:151-7. doi:10.1038/nrgl527
    • (2005) Nat Rev Genet , vol.6 , pp. 151-157
    • Dermitzakis, E.T.1    Reymond, A.2    Antonarakis, S.E.3
  • 38
    • 58249088751 scopus 로고    scopus 로고
    • MicroRNAs: Target recognition and regulatory functions
    • Bartel DP. microRNAs: target recognition and regulatory functions. Cell (2009) 136:215-33. doi:10.1016/j.cell.2009.01.002
    • (2009) Cell , vol.136 , pp. 215-233
    • Bartel, D.P.1
  • 39
    • 26944498633 scopus 로고    scopus 로고
    • Prediction and validation of microRNAs and their targets
    • Bentwich I. Prediction and validation of microRNAs and their targets. FEBS Lett (2005) 579:5904-10. doi:10.1016/j.febslet.2005.09.040
    • (2005) FEBS Lett , vol.579 , pp. 5904-5910
    • Bentwich, I.1
  • 40
    • 84883856321 scopus 로고    scopus 로고
    • MicroRNA: Function, detection, and bioanalysis
    • Dong H, Lei J, Ding L, Wen Y, Ju H, Zhang X. microRNA: function, detection, and bioanalysis. Chern Rev (2013) 113:6207-33. doi:10.1021/cr300362f
    • (2013) Chern Rev , vol.113 , pp. 6207-6233
    • Dong, H.1    Lei, J.2    Ding, L.3    Wen, Y.4    Ju, H.5    Zhang, X.6
  • 42
    • 61349194998 scopus 로고    scopus 로고
    • Overexpression of HMGA2 relates to reduction of the let-7 and its relationship to clin- icopathological features in pituitary adenomas
    • Qian ZR, Asa SL, Siomi H, Siomi MC, Yoshimoto K, Yamada S, et al. Overexpression of HMGA2 relates to reduction of the let-7 and its relationship to clin- icopathological features in pituitary adenomas. Mod Pathol (2009) 22:431-41. doi:10.1038/modpathol.2008.202
    • (2009) Mod Pathol , vol.22 , pp. 431-441
    • Qian, Z.R.1    Asa, S.L.2    Siomi, H.3    Siomi, M.C.4    Yoshimoto, K.5    Yamada, S.6
  • 43
    • 84865428087 scopus 로고    scopus 로고
    • Down regulation of HMG A-targeting microRNAs has a critical role in human pituitary tumorigenesis
    • Palmieri D, DAngelo D, Valentino T, De Martino I, Ferraro A, Wierinckx A, et al. Down regulation of HMG A-targeting microRNAs has a critical role in human pituitary tumorigenesis. Oncogene (2012) 31:3857-65. doi:10.1038/onc.2011.557
    • (2012) Oncogene , vol.31 , pp. 3857-3865
    • Palmieri, D.1    Dangelo, D.2    Valentino, T.3    De Martino, I.4    Ferraro, A.5    Wierinckx, A.6
  • 44
    • 84863583945 scopus 로고    scopus 로고
    • Altered microRNA expression profile in human pituitary GH adenomas: Down- regulation of miRNA targeting HMGAl, HMGA2, and E2F1
    • D’Angelo D, Palmieri D, Mussnich P, Roche M, Wierinckx A, Raverot G, et al. Altered microRNA expression profile in human pituitary GH adenomas: down- regulation of miRNA targeting HMGAl, HMGA2, and E2F1. J Clin Endocrinol Metab (2012) 97:E1128-38. doi:10.1210/jc.2011-3482
    • (2012) J Clin Endocrinol Metab , vol.97 , pp. 1128-1138
    • D’Angelo, D.1    Palmieri, D.2    Mussnich, P.3    Roche, M.4    Wierinckx, A.5    Raverot, G.6
  • 46
    • 84863495094 scopus 로고    scopus 로고
    • The hallmarks of cancer: A long non-coding RNA point of view
    • Gutschner T, Diederichs S. The hallmarks of cancer: a long non-coding RNA point of view. RNA Biol (2012) 9:703-19. doi:10.4161/rna.20481
    • (2012) RNA Biol , vol.9 , pp. 703-719
    • Gutschner, T.1    Diederichs, S.2
  • 48
    • 0346155809 scopus 로고    scopus 로고
    • Pseudogenes: Are they “junk” or functional DNA?
    • Balakirev ES, Ayala FJ. Pseudogenes: are they “junk” or functional DNA? Annu Rev Genet (2003) 37:123-51. doi:10.1146/annurev.genet.37.040103.103949
    • (2003) Annu Rev Genet , vol.37 , pp. 123-151
    • Balakirev, E.S.1    Ayala, F.J.2
  • 49
    • 77953957633 scopus 로고    scopus 로고
    • A coding- independent function of gene and pseudogene mRNAs regulates tumour biology
    • Poliseno L, Salmena L, Zhang J, Carver B, Haveman WJ, Pandolfi PP. A coding- independent function of gene and pseudogene mRNAs regulates tumour biology. Nature (2010) 465:1033-8. doi:10.1038/nature09144
    • (2010) Nature , vol.465 , pp. 1033-1038
    • Poliseno, L.1    Salmena, L.2    Zhang, J.3    Carver, B.4    Haveman, W.J.5    Pandolfi, P.P.6
  • 52
    • 84920620851 scopus 로고    scopus 로고
    • HMGAl-pseudogene overexpression contributes to cancer progression
    • Esposito F, De Martino M, Forzati F, Fusco A. HMGAl-pseudogene overexpression contributes to cancer progression. Cell Cycle (2014) 13:3636-9. doi:10.4161/15384101.2014.974440
    • (2014) Cell Cycle , vol.13 , pp. 3636-3639
    • Esposito, F.1    De Martino, M.2    Forzati, F.3    Fusco, A.4
  • 53
    • 84875590101 scopus 로고    scopus 로고
    • Long noncoding RNAs: Past, present, and future
    • Kung JTY, Colognori D, Lee JT. Long noncoding RNAs: past, present, and future. Genetics (2013) 193:651-69. doi:10.1534/genetics.ll2.146704
    • (2013) Genetics , vol.193 , pp. 651-669
    • Kung, J.1    Colognori, D.2    Lee, J.T.3
  • 54
    • 84874931361 scopus 로고    scopus 로고
    • The impairment of the high mobility group A (HMGA) protein function contributes to the anticancer activity of trabectedin
    • D’Angelo D, Borbone E, Palmieri D, Uboldi S, Esposito F, Frapolli R, et al. The impairment of the high mobility group A (HMGA) protein function contributes to the anticancer activity of trabectedin. Eurf Cancer (2013) 49:1142-51. doi:10.1016/j.ejca.2012.10.014
    • (2013) Eurf Cancer , vol.49 , pp. 1142-1151
    • D’Angelo, D.1    Borbone, E.2    Palmieri, D.3    Uboldi, S.4    Esposito, F.5    Frapolli, R.6


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