Recurrent gain-of-function USP8 mutations in Cushing's disease

Cell Research

Volumn 25, Issue 3, 2015, Pages 306-317

  Ma, Zeng Yi ^a   Song, Zhi Jian ^b   Chen, Jian Hua ^b,c   Wang, Yong Fei ^a   Li, Shi Qi ^a   Zhou, Liang Fu ^a   Mao, Ying ^a   Li, Yi Ming ^a   Hu, Rong Gui ^d   Zhang, Zhao Yun ^a   Ye, Hong Ying ^a   Shen, Ming ^a   Shou, Xue Fei ^a   Li, Zhi Qiang ^b   Peng, Hong ^d   Wang, Qing Zhong ^b   Zhou, Dai Zhan ^b   Qin, Xiao Lan ^b   Ji, Jue ^b   Zheng, Jie ^b   Chen, Hong ^a   Wang, Yin ^a   Geng, Dao Ying ^a   Tang, Wei Jun ^a   Fu, Chao Wei ^a   Shi, Zhi Feng ^a   Zhang, Yi Chao ^a   Ye, Zhao ^a   He, Wen Qiang ^a   Zhang, Qi Lin ^a   Tang, Qi Sheng ^a   Xie, Rong ^a   Shen, Jia Wei ^b   Wen, Zu Jia ^b   Zhou, Juan ^b   Wang, Tao ^e   Huang, Shan ^e   Qiu, Hui Jia ^a   Qiao, Ni Dan ^a   Zhang, Yi ^a   Pan, Li ^a   Bao, Wei Min ^a   Liu, Ying Chao ^f   Huang, Chuan Xin ^c   Shi, Yong Yong ^b,g   Zhao, Yao ^a   more..

^a FUDAN UNIVERSITY   (China)

^b SHANGHAI JIAO TONG UNIVERSITY   (China)

^c SHANGHAI JIAO TONG UNIVERSITY SCHOOL OF MEDICINE   (China)

^d INSTITUTE OF BIOCHEMISTRY AND CELL BIOLOGY   (China)

^e Urology Institute of Fudan University   (China)

^f SHANDONG UNIVERSITY   (China)

^g QINGDAO UNIVERSITY   (China)

Author keywords

Cushing's disease; mutation; pituitary adenomas; USP8; whole exome sequencing

Indexed keywords

CORTICOTROPIN; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; ESCRT PROTEIN; GEFITINIB; PROOPIOMELANOCORTIN; PROTEIN 14 3 3; PROTEIN BINDING; PROTEIN KINASE INHIBITOR; PROTEINASE; QUINAZOLINE DERIVATIVE; SMALL INTERFERING RNA; UBIQUITIN THIOLESTERASE; USP8 PROTEIN, HUMAN;

ACTH-SECRETING PITUITARY ADENOMA; ADOLESCENT; ADULT; ANTAGONISTS AND INHIBITORS; CUSHING SYNDROME; DNA SEQUENCE; EXOME; FEMALE; GENETICS; HUMAN; MALE; METABOLISM; MIDDLE AGED; NUCLEOTIDE SEQUENCE; RNA INTERFERENCE; SECRETION (PROCESS); YOUNG ADULT;

14-3-3 PROTEINS; ACTH-SECRETING PITUITARY ADENOMA; ADOLESCENT; ADRENOCORTICOTROPIC HORMONE; ADULT; BASE SEQUENCE; CUSHING SYNDROME; ENDOPEPTIDASES; ENDOSOMAL SORTING COMPLEXES REQUIRED FOR TRANSPORT; EXOME; FEMALE; HUMANS; MALE; MIDDLE AGED; PRO-OPIOMELANOCORTIN; PROTEIN BINDING; PROTEIN KINASE INHIBITORS; QUINAZOLINES; RECEPTOR, EPIDERMAL GROWTH FACTOR; RNA INTERFERENCE; RNA, SMALL INTERFERING; SEQUENCE ANALYSIS, DNA; UBIQUITIN THIOLESTERASE; YOUNG ADULT;

EID: 84924508821     PISSN: 10010602     EISSN: 17487838     Source Type: Journal    
DOI: 10.1038/cr.2015.20     Document Type: Article

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