Lipid flippase subunit Cdc50 mediates drug resistance and virulence in Cryptococcus neoformans

mBio

Volumn 7, Issue 3, 2016, Pages

  Huang, Wei ^a   Liao, Guojian ^a,c   Baker, Gregory M ^a   Wang, Yina ^a   Lau, Richard ^a   Paderu, Padmaja ^a   Perlin, David S ^a,b   Xue, Chaoyang ^a,b  

^a PUBLIC HEALTH RESEARCH INSTITUTE   (United States)

^b RUTGERS NEW JERSEY MEDICAL SCHOOL   (United States)

^c SOUTHWEST UNIVERSITY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

CASPOFUNGIN; MEMBRANE PROTEIN; PHOSPHATIDYLSERINE; PROTEIN CDC50; UNCLASSIFIED DRUG; ANTIFUNGAL AGENT; ECHINOCANDIN; FLUCONAZOLE; FUNGAL PROTEIN; LIPOPEPTIDE; PHOSPHOLIPID TRANSFER PROTEIN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIFUNGAL RESISTANCE; ARTICLE; CDC50 GENE; CELL MEMBRANE; CELL SURFACE; CONTROLLED STUDY; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DRUG UPTAKE; FEMALE; FUNGAL CELL; FUNGAL VIRULENCE; GENE; GENE DELETION; GENE DISRUPTION; INTRACELLULAR TRANSPORT; MACROPHAGE FUNCTION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN LOCALIZATION; ANIMAL; CHEMISTRY; DISEASE MODEL; DRUG EFFECTS; ENZYMOLOGY; GENETICS; HUMAN; IMMUNOLOGY; METABOLISM; MICROBIOLOGY; MUTATION; PATHOGENICITY; PATHOLOGY; VIRULENCE;

ANIMALS; ANTIFUNGAL AGENTS; CELL MEMBRANE; CRYPTOCOCCOSIS; CRYPTOCOCCUS NEOFORMANS; DISEASE MODELS, ANIMAL; DRUG RESISTANCE, FUNGAL; ECHINOCANDINS; FLUCONAZOLE; FUNGAL PROTEINS; GENE DELETION; HUMANS; LIPOPEPTIDES; MICE; MUTATION; PHOSPHATIDYLSERINES; PHOSPHOLIPID TRANSFER PROTEINS; VIRULENCE;

EID: 84978986136     PISSN: 21612129     EISSN: 21507511     Source Type: Journal    
DOI: 10.1128/mBio.00478-16     Document Type: Article

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