메뉴 건너뛰기




Volumn 10, Issue 5, 2011, Pages 618-628

Two major inositol transporters and their role in cryptococcal virulence

Author keywords

[No Author keywords available]

Indexed keywords

CARRIER PROTEIN; FUNGAL PROTEIN; INOSITOL;

EID: 79956026276     PISSN: 15359778     EISSN: None     Source Type: Journal    
DOI: 10.1128/EC.00327-10     Document Type: Article
Times cited : (31)

References (63)
  • 1
    • 0030668723 scopus 로고    scopus 로고
    • Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP
    • Alspaugh, J. A., J. R. Perfect, and J. Heitman. 1997. Cryptococcus neoformans mating and virulence are regulated by the G-protein alpha subunit GPA1 and cAMP. Genes Dev. 11:3206-3217.
    • (1997) Genes Dev , vol.11 , pp. 3206-3217
    • Alspaugh, J.A.1    Perfect, J.R.2    Heitman, J.3
  • 2
    • 0028363566 scopus 로고
    • INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter
    • Ambroziak, J., and S. A. Henry. 1994. INO2 and INO4 gene products, positive regulators of phospholipid biosynthesis in Saccharomyces cerevisiae, form a complex that binds to the INO1 promoter. J. Biol. Chem. 269:15344-15349.
    • (1994) J. Biol. Chem , vol.269 , pp. 15344-15349
    • Ambroziak, J.1    Henry, S.A.2
  • 3
    • 11144276482 scopus 로고    scopus 로고
    • Adenylyl cyclase-associated protein AcaI regulates virulence and differentiation of Cryptococcus neoformans via the cyclic AMP-protein kinase A cascade
    • Bahn, Y. S., J. K. Hicks, S. S. Giles, G. M. Cox, and J. Heitman. 2004. Adenylyl cyclase-associated protein AcaI regulates virulence and differentiation of Cryptococcus neoformans via the cyclic AMP-protein kinase A cascade. Eukaryot. Cell 3:1476-1491.
    • (2004) Eukaryot. Cell , vol.3 , pp. 1476-1491
    • Bahn, Y.S.1    Hicks, J.K.2    Giles, S.S.3    Cox, G.M.4    Heitman, J.5
  • 4
    • 33845617675 scopus 로고    scopus 로고
    • Sensing the environment: Lessons from fungi
    • Bahn, Y. S., et al. 2007. Sensing the environment: lessons from fungi. Nat. Rev. Microbiol. 5:57-69.
    • (2007) Nat. Rev. Microbiol , vol.5 , pp. 57-69
    • Bahn, Y.S.1
  • 5
    • 0016912778 scopus 로고
    • The utilization of sugars by yeasts
    • Barnett, J. A. 1976. The utilization of sugars by yeasts. Adv. Carbohydr. Chem. Biochem. 32:125-234.
    • (1976) Adv. Carbohydr. Chem. Biochem , vol.32 , pp. 125-234
    • Barnett, J.A.1
  • 9
    • 11244299412 scopus 로고    scopus 로고
    • Role of the unfolded protein response pathway in secretory stress and regulation of INO1 expression in Saccharomyces cerevisiae
    • Chang, H. J., S. A. Jesch, M. L. Gaspar, and S. A. Henry. 2004. Role of the unfolded protein response pathway in secretory stress and regulation of INO1 expression in Saccharomyces cerevisiae. Genetics 168:1899-1913.
    • (2004) Genetics , vol.168 , pp. 1899-1913
    • Chang, H.J.1    Jesch, S.A.2    Gaspar, M.L.3    Henry, S.A.4
  • 11
    • 46249088210 scopus 로고    scopus 로고
    • Candida albicans uses multiple mechanisms to acquire the essential metabolite inositol during infection
    • Chen, Y. L., S. Kauffman, and T. B. Reynolds. 2008. Candida albicans uses multiple mechanisms to acquire the essential metabolite inositol during infection. Infect. Immun. 76:2793-2801.
    • (2008) Infect. Immun , vol.76 , pp. 2793-2801
    • Chen, Y.L.1    Kauffman, S.2    Reynolds, T.B.3
  • 13
    • 0000050123 scopus 로고
    • Inositol mutants of Saccharomyces cerevisiae: Mapping the ino1 locus and characterizing alleles of the ino1, ino2 and ino4 loci
    • Donahue, T. F., and S. A. Henry. 1981. Inositol mutants of Saccharomyces cerevisiae: mapping the ino1 locus and characterizing alleles of the ino1, ino2 and ino4 loci. Genetics 98:491-503.
    • (1981) Genetics , vol.98 , pp. 491-503
    • Donahue, T.F.1    Henry, S.A.2
  • 14
    • 0029093829 scopus 로고
    • Functional expression of a myo-inositol/H+ symporter from Leishmania donovani
    • Drew, M. E., et al. 1995. Functional expression of a myo-inositol/H+ symporter from Leishmania donovani. Mol. Cell. Biol. 15:5508-5515.
    • (1995) Mol. Cell. Biol , vol.15 , pp. 5508-5515
    • Drew, M.E.1
  • 15
    • 0036677944 scopus 로고    scopus 로고
    • Inositol and higher inositol phosphates in neural tissues: Homeostasis, metabolism and functional significance
    • Fisher, S. K., J. E. Novak, and B. W. Agranoff. 2002. Inositol and higher inositol phosphates in neural tissues: homeostasis, metabolism and functional significance. J. Neurochem. 82:736-754.
    • (2002) J. Neurochem , vol.82 , pp. 736-754
    • Fisher, S.K.1    Novak, J.E.2    Agranoff, B.W.3
  • 16
    • 54249109568 scopus 로고    scopus 로고
    • PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans
    • Gerik, K. J., S. R. Bhimireddy, J. S. Ryerse, C. A. Specht, and J. K. Lodge. 2008. PKC1 is essential for protection against both oxidative and nitrosative stresses, cell integrity, and normal manifestation of virulence factors in the pathogenic fungus Cryptococcus neoformans. Eukaryot. Cell 7:1685-1698.
    • (2008) Eukaryot. Cell , vol.7 , pp. 1685-1698
    • Gerik, K.J.1    Bhimireddy, S.R.2    Ryerse, J.S.3    Specht, C.A.4    Lodge, J.K.5
  • 17
    • 26944477777 scopus 로고    scopus 로고
    • Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans
    • Gerik, K. J., et al. 2005. Cell wall integrity is dependent on the PKC1 signal transduction pathway in Cryptococcus neoformans. Mol. Microbiol. 58:393-408.
    • (2005) Mol. Microbiol , vol.58 , pp. 393-408
    • Gerik, K.J.1
  • 18
    • 0034075621 scopus 로고    scopus 로고
    • Regulation of the yeast INO1 gene. The products of the INO2, INO4 and OPI1 regulatory genes are not required for repression in response to inositol
    • Graves, J. A., and S. A. Henry. 2000. Regulation of the yeast INO1 gene. The products of the INO2, INO4 and OPI1 regulatory genes are not required for repression in response to inositol. Genetics 154:1485-1495.
    • (2000) Genetics , vol.154 , pp. 1485-1495
    • Graves, J.A.1    Henry, S.A.2
  • 19
    • 26244457444 scopus 로고    scopus 로고
    • Gα subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiae
    • Harashima, T., and J. Heitman. 2005. Gα subunit Gpa2 recruits kelch repeat subunits that inhibit receptor-G protein coupling during cAMP-induced dimorphic transitions in Saccharomyces cerevisiae. Mol. Biol. Cell 16:4557-4571.
    • (2005) Mol. Biol. Cell , vol.16 , pp. 4557-4571
    • Harashima, T.1    Heitman, J.2
  • 20
    • 0017693654 scopus 로고
    • Diagnostic medium containing inositol, urea, and caffeic acid for selective growth of Cryptococcus neoformans
    • Healy, M. E., C. L. Dillavou, and G. E. Taylor. 1977. Diagnostic medium containing inositol, urea, and caffeic acid for selective growth of Cryptococcus neoformans. J. Clin. Microbiol. 6:387-391.
    • (1977) J. Clin. Microbiol , vol.6 , pp. 387-391
    • Healy, M.E.1    Dillavou, C.L.2    Taylor, G.E.3
  • 21
    • 23344448602 scopus 로고    scopus 로고
    • The role and mechanism of diacylglycerol-protein kinase C1 signaling in melanogenesis by Cryptococcus neoformans
    • Heung, L. J., A. E. Kaiser, C. Luberto, and M. Del Poeta. 2005. The role and mechanism of diacylglycerol-protein kinase C1 signaling in melanogenesis by Cryptococcus neoformans. J. Biol. Chem. 280:28547-28555.
    • (2005) J. Biol. Chem , vol.280 , pp. 28547-28555
    • Heung, L.J.1    Kaiser, A.E.2    Luberto, C.3    del Poeta, M.4
  • 22
    • 2442701773 scopus 로고    scopus 로고
    • The sphingolipid pathway regulates Pkc1 through the formation of diacylglycerol in Cryptococcus neoformans
    • Heung, L. J., C. Luberto, A. Plowden, Y. A. Hannun, and M. Del Poeta. 2004. The sphingolipid pathway regulates Pkc1 through the formation of diacylglycerol in Cryptococcus neoformans. J. Biol. Chem. 279:21144-21153.
    • (2004) J. Biol. Chem , vol.279 , pp. 21144-21153
    • Heung, L.J.1    Luberto, C.2    Plowden, A.3    Hannun, Y.A.4    del Poeta, M.5
  • 23
    • 29144439796 scopus 로고    scopus 로고
    • Pde1 phosphodiesterase modulates cyclic AMP levels through a protein kinase A-mediated negative feedback loop in Cryptococcus neoformans
    • Hicks, J. K., Y. S. Bahn, and J. Heitman. 2005. Pde1 phosphodiesterase modulates cyclic AMP levels through a protein kinase A-mediated negative feedback loop in Cryptococcus neoformans. Eukaryot. Cell 4:1971-1981.
    • (2005) Eukaryot. Cell , vol.4 , pp. 1971-1981
    • Hicks, J.K.1    Bahn, Y.S.2    Heitman, J.3
  • 24
    • 27244439061 scopus 로고    scopus 로고
    • Deciphering the model pathogenic fungus Cryptococcus neoformans
    • Idnurm, A., et al. 2005. Deciphering the model pathogenic fungus Cryptococcus neoformans. Nat. Rev. Microbiol. 3:753-764.
    • (2005) Nat. Rev. Microbiol , vol.3 , pp. 753-764
    • Idnurm, A.1
  • 25
    • 0346914338 scopus 로고    scopus 로고
    • High-affinity myo-inositol transport in Candida albicans: Substrate specificity and pharmacology
    • Jin, J. H., and A. Seyfang. 2003. High-affinity myo-inositol transport in Candida albicans: substrate specificity and pharmacology. Microbiology 149: 3371-3381.
    • (2003) Microbiology , vol.149 , pp. 3371-3381
    • Jin, J.H.1    Seyfang, A.2
  • 26
    • 47249127597 scopus 로고    scopus 로고
    • Dimerization of yeast transcription factors Ino2 and Ino4 is regulated by precursors of phospholipid biosynthesis mediated by Opi1 repressor
    • Kumme, J., M. Dietz, C. Wagner, and H. J. Schuller. 2008. Dimerization of yeast transcription factors Ino2 and Ino4 is regulated by precursors of phospholipid biosynthesis mediated by Opi1 repressor. Curr. Genet. 54:35-45.
    • (2008) Curr. Genet , vol.54 , pp. 35-45
    • Kumme, J.1    Dietz, M.2    Wagner, C.3    Schuller, H.J.4
  • 27
    • 0028819235 scopus 로고
    • Regulation of inositol transport in Saccharomyces cerevisiae involves inositol-induced changes in permease stability and endocytic degradation in the vacuole
    • Lai, K., C. P. Bolognese, S. Swift, and P. McGraw. 1995. Regulation of inositol transport in Saccharomyces cerevisiae involves inositol-induced changes in permease stability and endocytic degradation in the vacuole. J. Biol. Chem. 270:2525-2534.
    • (1995) J. Biol. Chem , vol.270 , pp. 2525-2534
    • Lai, K.1    Bolognese, C.P.2    Swift, S.3    McGraw, P.4
  • 28
    • 0028107569 scopus 로고
    • Dual control of inositol transport in Saccharomyces cerevisiae by irreversible inactivation of permease and regulation of permease synthesis by INO2, INO4, and OPI1
    • Lai, K., and P. McGraw. 1994. Dual control of inositol transport in Saccharomyces cerevisiae by irreversible inactivation of permease and regulation of permease synthesis by INO2, INO4, and OPI1. J. Biol. Chem. 269:2245-2251.
    • (1994) J. Biol. Chem , vol.269 , pp. 2245-2251
    • Lai, K.1    McGraw, P.2
  • 29
    • 36448991500 scopus 로고    scopus 로고
    • Clustal W and Clustal X version 2.0
    • Larkin, M. A., et al. 2007. Clustal W and Clustal X version 2.0. Bioinformatics 23:2947-2948.
    • (2007) Bioinformatics , vol.23 , pp. 2947-2948
    • Larkin, M.A.1
  • 30
    • 0034444677 scopus 로고    scopus 로고
    • Signal transduction cascades regulating fungal development and virulence
    • Lengeler, K. B., et al. 2000. Signal transduction cascades regulating fungal development and virulence. Microbiol. Mol. Biol. Rev. 64:746-785.
    • (2000) Microbiol. Mol. Biol. Rev , vol.64 , pp. 746-785
    • Lengeler, K.B.1
  • 31
    • 20044380139 scopus 로고    scopus 로고
    • The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans
    • Loftus, B. J., et al. 2005. The genome of the basidiomycetous yeast and human pathogen Cryptococcus neoformans. Science 307:1321-1324.
    • (2005) Science , vol.307 , pp. 1321-1324
    • Loftus, B.J.1
  • 32
    • 0035863069 scopus 로고    scopus 로고
    • Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans
    • Luberto, C., et al. 2001. Roles for inositol-phosphoryl ceramide synthase 1 (IPC1) in pathogenesis of C. neoformans. Genes Dev. 15:201-212.
    • (2001) Genes Dev , vol.15 , pp. 201-212
    • Luberto, C.1
  • 33
    • 33744783109 scopus 로고    scopus 로고
    • Phosphatidylinositol synthesis is essential in bloodstream form Trypanosoma brucei
    • Martin, K. L., and T. K. Smith. 2006. Phosphatidylinositol synthesis is essential in bloodstream form Trypanosoma brucei. Biochem. J. 396:287-295.
    • (2006) Biochem. J , vol.396 , pp. 287-295
    • Martin, K.L.1    Smith, T.K.2
  • 34
    • 68749094985 scopus 로고    scopus 로고
    • The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target
    • Mina, J. G., et al. 2009. The Trypanosoma brucei sphingolipid synthase, an essential enzyme and drug target. Mol. Biochem. Parasitol. 168:16-23.
    • (2009) Mol. Biochem. Parasitol , vol.168 , pp. 16-23
    • Mina, J.G.1
  • 35
    • 0032743056 scopus 로고    scopus 로고
    • Inositol synthesis and catabolism in Cryptococcus neoformans
    • Molina, Y., S. E. Ramos, T. Douglass, and L. S. Klig. 1999. Inositol synthesis and catabolism in Cryptococcus neoformans. Yeast 15:1657-1667.
    • (1999) Yeast , vol.15 , pp. 1657-1667
    • Molina, Y.1    Ramos, S.E.2    Douglass, T.3    Klig, L.S.4
  • 36
    • 1842763132 scopus 로고    scopus 로고
    • Substrate specificity of the Leishmania donovani myo-inositol transporter: Critical role of inositol C-2, C-3 and C-5 hydroxyl groups
    • Mongan, T. P., S. Ganapasam, S. B. Hobbs, and A. Seyfang. 2004. Substrate specificity of the Leishmania donovani myo-inositol transporter: critical role of inositol C-2, C-3 and C-5 hydroxyl groups. Mol. Biochem. Parasitol. 135:133-141.
    • (2004) Mol. Biochem. Parasitol , vol.135 , pp. 133-141
    • Mongan, T.P.1    Ganapasam, S.2    Hobbs, S.B.3    Seyfang, A.4
  • 37
    • 0031894125 scopus 로고    scopus 로고
    • Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Schizosaccharomyces pombe
    • Niederberger, C., et al. 1998. Exogenous inositol and genes responsible for inositol transport are required for mating and sporulation in Schizosaccharomyces pombe. Curr. Genet. 33:255-261.
    • (1998) Curr. Genet , vol.33 , pp. 255-261
    • Niederberger, C.1
  • 38
    • 0041971075 scopus 로고    scopus 로고
    • Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and α isolates
    • Nielsen, K., et al. 2003. Sexual cycle of Cryptococcus neoformans var. grubii and virulence of congenic a and α isolates. Infect. Immun. 71:4831-4841.
    • (2003) Infect. Immun , vol.71 , pp. 4831-4841
    • Nielsen, K.1
  • 39
    • 0029044593 scopus 로고
    • Isolation and characterization of genes that promote the expression of inositol transporter gene ITR1 in Saccharomyces cerevisiae
    • Nikawa, J., and K. Hosaka. 1995. Isolation and characterization of genes that promote the expression of inositol transporter gene ITR1 in Saccharomyces cerevisiae. Mol. Microbiol. 16:301-308.
    • (1995) Mol. Microbiol , vol.16 , pp. 301-308
    • Nikawa, J.1    Hosaka, K.2
  • 40
    • 0027760941 scopus 로고
    • Differential regulation of two myo-inositol transporter genes of Saccharomyces cerevisiae
    • Nikawa, J., K. Hosaka, and S. Yamashita. 1993. Differential regulation of two myo-inositol transporter genes of Saccharomyces cerevisiae. Mol. Microbiol. 10:955-961.
    • (1993) Mol. Microbiol , vol.10 , pp. 955-961
    • Nikawa, J.1    Hosaka, K.2    Yamashita, S.3
  • 41
    • 0025848024 scopus 로고
    • Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae
    • Nikawa, J., Y. Tsukagoshi, and S. Yamashita. 1991. Isolation and characterization of two distinct myo-inositol transporter genes of Saccharomyces cerevisiae. J. Biol. Chem. 266:11184-11191.
    • (1991) J. Biol. Chem , vol.266 , pp. 11184-11191
    • Nikawa, J.1    Tsukagoshi, Y.2    Yamashita, S.3
  • 42
    • 0034267634 scopus 로고    scopus 로고
    • Inositol metabolism in Trypanosoma cruzi: Potential target for chemotherapy against Chagas' disease
    • Oliveira, M. M., and M. Einicker-Lamas. 2000. Inositol metabolism in Trypanosoma cruzi: potential target for chemotherapy against Chagas' disease. An. Acad. Bras Cienc. 72:413-419.
    • (2000) An. Acad. Bras Cienc , vol.72 , pp. 413-419
    • Oliveira, M.M.1    Einicker-Lamas, M.2
  • 43
    • 0030203863 scopus 로고    scopus 로고
    • TreeView: An application to display phylogenetic trees on personal computers
    • Page, R. D. 1996. TreeView: an application to display phylogenetic trees on personal computers. Comput. Appl. Biosci. 12:357-358.
    • (1996) Comput. Appl. Biosci , vol.12 , pp. 357-358
    • Page, R.D.1
  • 44
    • 62349130224 scopus 로고    scopus 로고
    • Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS
    • Park, B. J., et al. 2009. Estimation of the current global burden of cryptococcal meningitis among persons living with HIV/AIDS. AIDS 23:525-530.
    • (2009) AIDS , vol.23 , pp. 525-530
    • Park, B.J.1
  • 46
    • 40649118980 scopus 로고    scopus 로고
    • Epidemiology and management of cryptococcal meningitis: Developments and challenges
    • Pukkila-Worley, R., and E. Mylonakis. 2008. Epidemiology and management of cryptococcal meningitis: developments and challenges. Expert Opin. Pharmacother. 9:551-560.
    • (2008) Expert Opin. Pharmacother , vol.9 , pp. 551-560
    • Pukkila-Worley, R.1    Mylonakis, E.2
  • 47
    • 66849140787 scopus 로고    scopus 로고
    • Strategies for acquiring the phospholipid metabolite inositol in pathogenic bacteria, fungi and protozoa: Making it and taking it
    • Reynolds, T. B. 2009. Strategies for acquiring the phospholipid metabolite inositol in pathogenic bacteria, fungi and protozoa: making it and taking it. Microbiology 155:1386-1396.
    • (2009) Microbiology , vol.155 , pp. 1386-1396
    • Reynolds, T.B.1
  • 48
    • 0030063630 scopus 로고    scopus 로고
    • Inositol transport in Saccharomyces cerevisiae is regulated by transcriptional and degradative endocytic mechanisms during the growth cycle that are distinct from inositol-induced regulation
    • Robinson, K. S., K. Lai, T. A. Cannon, and P. McGraw. 1996. Inositol transport in Saccharomyces cerevisiae is regulated by transcriptional and degradative endocytic mechanisms during the growth cycle that are distinct from inositol-induced regulation. Mol. Biol. Cell 7:81-89.
    • (1996) Mol. Biol. Cell , vol.7 , pp. 81-89
    • Robinson, K.S.1    Lai, K.2    Cannon, T.A.3    McGraw, P.4
  • 49
    • 0034051668 scopus 로고    scopus 로고
    • Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter
    • Seyfang, A., and S. M. Landfear. 2000. Four conserved cytoplasmic sequence motifs are important for transport function of the Leishmania inositol/H(+) symporter. J. Biol. Chem. 275:5687-5693.
    • (2000) J. Biol. Chem , vol.275 , pp. 5687-5693
    • Seyfang, A.1    Landfear, S.M.2
  • 50
    • 33749242244 scopus 로고    scopus 로고
    • The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal dissemination to the central nervous system
    • Shea, J. M., T. B. Kechichian, C. Luberto, and M. Del Poeta. 2006. The cryptococcal enzyme inositol phosphosphingolipid-phospholipase C confers resistance to the antifungal effects of macrophages and promotes fungal dissemination to the central nervous system. Infect. Immun. 74: 5977-5988.
    • (2006) Infect. Immun , vol.74 , pp. 5977-5988
    • Shea, J.M.1    Kechichian, T.B.2    Luberto, C.3    del Poeta, M.4
  • 51
    • 0030062185 scopus 로고    scopus 로고
    • Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome
    • Shetty, H. U., H. W. Holloway, L. D. Acevedo, and Z. Galdzicki. 1996. Brain accumulation of myo-inositol in the trisomy 16 mouse, an animal model of Down's syndrome. Biochem. J. 313:31-33.
    • (1996) Biochem. J , vol.313 , pp. 31-33
    • Shetty, H.U.1    Holloway, H.W.2    Acevedo, L.D.3    Galdzicki, Z.4
  • 52
    • 0030038202 scopus 로고    scopus 로고
    • Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease
    • Shetty, H. U., H. W. Holloway, and M. B. Schapiro. 1996. Cerebrospinal fluid and plasma distribution of myo-inositol and other polyols in Alzheimer disease. Clin. Chem. 42:298-302.
    • (1996) Clin. Chem , vol.42 , pp. 298-302
    • Shetty, H.U.1    Holloway, H.W.2    Schapiro, M.B.3
  • 53
    • 0023789039 scopus 로고
    • Myo-inositol transport through the blood-brain barrier
    • Spector, R. 1988. Myo-inositol transport through the blood-brain barrier. Neurochem. Res. 13:785-787.
    • (1988) Neurochem. Res , vol.13 , pp. 785-787
    • Spector, R.1
  • 54
    • 0016788039 scopus 로고
    • Myo-inositol transport in the central nervous system
    • Spector, R., and A. V. Lorenzo. 1975. Myo-inositol transport in the central nervous system. Am. J. Physiol. 228:1510-1518.
    • (1975) Am. J. Physiol , vol.228 , pp. 1510-1518
    • Spector, R.1    Lorenzo, A.V.2
  • 55
    • 0016834188 scopus 로고
    • The origin of myo-inositol in brain, cerebrospinal fluid and choroid plexus
    • Spector, R., and A. V. Lorenzo. 1975. The origin of myo-inositol in brain, cerebrospinal fluid and choroid plexus. J. Neurochem. 25:353-354.
    • (1975) J. Neurochem , vol.25 , pp. 353-354
    • Spector, R.1    Lorenzo, A.V.2
  • 56
    • 0347063857 scopus 로고    scopus 로고
    • Cryptococcus neoformans gene expression during experimental cryptococcal meningitis
    • Steen, B. R., et al. 2003. Cryptococcus neoformans gene expression during experimental cryptococcal meningitis. Eukaryot. Cell 2:1336-1349.
    • (2003) Eukaryot. Cell , vol.2 , pp. 1336-1349
    • Steen, B.R.1    Et al.2
  • 57
    • 40849083930 scopus 로고    scopus 로고
    • Trypanosomatid and fungal glycolipids and sphingolipids as infectivity factors and potential targets for development of new therapeutic strategies
    • Suzuki, E., et al. 2008. Trypanosomatid and fungal glycolipids and sphingolipids as infectivity factors and potential targets for development of new therapeutic strategies. Biochim. Biophys. Acta 1780:362-369.
    • (2008) Biochim. Biophys. Acta , vol.1780 , pp. 362-369
    • Suzuki, E.1
  • 58
    • 0032696034 scopus 로고    scopus 로고
    • The Candida albicans phospholipomannan is a family of glycolipids presenting phosphoinositolmannosides with long linear chains of β-1,2-linked mannose residues
    • Trinel, P. A., et al. 1999. The Candida albicans phospholipomannan is a family of glycolipids presenting phosphoinositolmannosides with long linear chains of β-1,2-linked mannose residues. J. Biol. Chem. 274:30520-30526.
    • (1999) J. Biol. Chem , vol.274 , pp. 30520-30526
    • Trinel, P.A.1
  • 59
    • 0029152841 scopus 로고
    • Unusual effect of myo-inositol on phospholipid biosynthesis in Cryptococcus neoformans
    • Vincent, V. L., and L. S. Klig. 1995. Unusual effect of myo-inositol on phospholipid biosynthesis in Cryptococcus neoformans. Microbiology 141: 1829-1837.
    • (1995) Microbiology , vol.141 , pp. 1829-1837
    • Vincent, V.L.1    Klig, L.S.2
  • 60
    • 0033178303 scopus 로고    scopus 로고
    • Signal transduction cascades regulating mating, filamentation, and virulence in Cryptococcus neoformans
    • Wang, P., and J. Heitman. 1999. Signal transduction cascades regulating mating, filamentation, and virulence in Cryptococcus neoformans. Curr. Opin. Microbiol. 2:358-362.
    • (1999) Curr. Opin. Microbiol , vol.2 , pp. 358-362
    • Wang, P.1    Heitman, J.2
  • 61
    • 79952133198 scopus 로고    scopus 로고
    • Role of an expanded inositol transporter repertoire in Cryptococcus neoformans sexual reproduction and virulence
    • Xue, C., et al. 2010. Role of an expanded inositol transporter repertoire in Cryptococcus neoformans sexual reproduction and virulence. mBio 1:e00084-e00010.
    • (2010) MBio , vol.1
    • Xue, C.1
  • 62
    • 34249882487 scopus 로고    scopus 로고
    • The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants
    • Xue, C., Y. Tada, X. Dong, and J. Heitman. 2007. The human fungal pathogen Cryptococcus can complete its sexual cycle during a pathogenic association with plants. Cell Host Microbe 1:263-273.
    • (2007) Cell Host Microbe , vol.1 , pp. 263-273
    • Xue, C.1    Tada, Y.2    Dong, X.3    Heitman, J.4
  • 63
    • 74549205784 scopus 로고    scopus 로고
    • Degradation of host sphingomyelin is essential for Leishmania virulence
    • e1000692
    • Zhang, O., et al. 2009. Degradation of host sphingomyelin is essential for Leishmania virulence. PLoS Pathog. 5:e1000692.
    • (2009) PLoS Pathog , vol.5
    • Zhang, O.1    Et al.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.