메뉴 건너뛰기




Volumn 11, Issue 2, 2016, Pages

White pitaya (Hylocereus undatus) juice attenuates insulin resistance and hepatic steatosis in diet-induced obese mice

Author keywords

[No Author keywords available]

Indexed keywords

ADIPONECTIN; ANTIDIABETIC AGENT; ANTILIPEMIC AGENT; HYLOCEREUS UNDATUS EXTRACT; NEUROPEPTIDE Y; PLANT EXTRACT; UNCLASSIFIED DRUG; CYTOKINE; LIPID;

EID: 84978952238     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0149670     Document Type: Article
Times cited : (54)

References (45)
  • 1
    • 28244481816 scopus 로고    scopus 로고
    • The metabolic syndrome
    • PMID: WOS:000233777900013
    • Balkau B, Eschwege E. The metabolic syndrome. Lancet. 2005; 366(9501):1921-. doi: 10.1016/S0140-6736(05)67777-X PMID: WOS:000233777900013.
    • (2005) Lancet , vol.366 , Issue.9501 , pp. 1921
    • Balkau, B.1    Eschwege, E.2
  • 2
    • 84862636851 scopus 로고    scopus 로고
    • Current treatment options for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis
    • PMID: WOS:000306217200009
    • Beaton MD. Current treatment options for nonalcoholic fatty liver disease and nonalcoholic steatohepatitis. Can J Gastroenterol. 2012; 26(6):353-7. PMID: WOS:000306217200009.
    • (2012) Can J Gastroenterol , vol.26 , Issue.6 , pp. 353-357
    • Beaton, M.D.1
  • 3
    • 50049086521 scopus 로고    scopus 로고
    • The emerging genetic architecture of type 2 diabetes
    • PMID: WOS:000258939500007
    • Doria A, Patti ME, Kahn CR. The emerging genetic architecture of type 2 diabetes. Cell Metab. 2008; 8 (3):186-200. doi: 10.1016/j.cmet.2008.08.006 PMID: WOS:000258939500007.
    • (2008) Cell Metab , vol.8 , Issue.3 , pp. 186-200
    • Doria, A.1    Patti, M.E.2    Kahn, C.R.3
  • 4
    • 67649793700 scopus 로고    scopus 로고
    • The genetic contribution to non-syndromic human obesity
    • PMID: WOS:000267142100011
    • Walley AJ, Asher JE, Froguel P. The genetic contribution to non-syndromic human obesity. Nat Rev Genet. 2009; 10(7):431-42. doi: 10.1038/nrg2594 PMID: WOS:000267142100011.
    • (2009) Nat Rev Genet , vol.10 , Issue.7 , pp. 431-442
    • Walley, A.J.1    Asher, J.E.2    Froguel, P.3
  • 5
    • 34249650125 scopus 로고    scopus 로고
    • Insulin resistance in hepatocytes and sinusoidal liver cells: Mechanisms and consequences
    • PMID: WOS:000247706700021
    • Leclercq IA, Morais ADS, Schroyen B, Van Hul N, Geerts A. Insulin resistance in hepatocytes and sinusoidal liver cells: Mechanisms and consequences. J Hepatol. 2007; 47(1):142-56. doi: 10.1016/j.jhep.2007.04.002 PMID: WOS:000247706700021.
    • (2007) J Hepatol , vol.47 , Issue.1 , pp. 142-156
    • Leclercq, I.A.1    Morais, A.D.S.2    Schroyen, B.3    Van Hul, N.4    Geerts, A.5
  • 6
    • 33846422032 scopus 로고    scopus 로고
    • Obesity and diabetes in the developing world - A growing challenge
    • PMID: WOS:000243488100003
    • Hossain P, Kawar B, Nahas ME. Obesity and diabetes in the developing world - A growing challenge. New Engl J Med. 2007; 356(3):213-5. doi: 10.1056/Nejmp068177 PMID: WOS:000243488100003.
    • (2007) New Engl J Med , vol.356 , Issue.3 , pp. 213-215
    • Hossain, P.1    Kawar, B.2    Nahas, M.E.3
  • 7
    • 20944450486 scopus 로고    scopus 로고
    • Insulin resistance in nondiabetic patients with non-alcoholic fatty liver disease: Sites and mechanisms
    • PMID: WOS:000228515900007
    • Bugianesi E, Gastaldelli A, Vanni E, Gambino R, Cassader M, Baldi S, et al. Insulin resistance in nondiabetic patients with non-alcoholic fatty liver disease: sites and mechanisms. Diabetologia. 2005; 48 (4):634-42. doi: 10.1007/s00125-005-1682-x PMID: WOS:000228515900007.
    • (2005) Diabetologia , vol.48 , Issue.4 , pp. 634-642
    • Bugianesi, E.1    Gastaldelli, A.2    Vanni, E.3    Gambino, R.4    Cassader, M.5    Baldi, S.6
  • 8
    • 52949122177 scopus 로고    scopus 로고
    • Antioxidant phytochemicals against type 2 diabetes
    • PMID: WOS:000208467500006
    • Dembinska-Kiec A, Mykkanen O, Kiec-Wilk B, Mykkanen H. Antioxidant phytochemicals against type 2 diabetes. Brit J Nutr. 2008; 99:Es109-Es17. doi: 10.1017/S000711450896579x PMID: WOS:000208467500006.
    • (2008) Brit J Nutr , vol.99 , pp. Es109-Es117
    • Dembinska-Kiec, A.1    Mykkanen, O.2    Kiec-Wilk, B.3    Mykkanen, H.4
  • 9
    • 0043286304 scopus 로고    scopus 로고
    • Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals
    • PMID: WOS:000184985500005
    • Liu RH. Health benefits of fruit and vegetables are from additive and synergistic combinations of phytochemicals. Am J Clin Nutr. 2003; 78(3):517s-20s. PMID: WOS:000184985500005.
    • (2003) Am J Clin Nutr , vol.78 , Issue.3 , pp. 517s-520s
    • Liu, R.H.1
  • 10
    • 36549001760 scopus 로고    scopus 로고
    • Nutraceuticals: Facts and fiction
    • PMID: 17976666
    • Espin JC, Garcia-Conesa MT, Tomas-Barberan FA. Nutraceuticals: facts and fiction. Phytochemistry. 2007; 68(22-24):2986-3008. doi: 10.1016/j.phytochem.2007.09.014 PMID: 17976666.
    • (2007) Phytochemistry , vol.68 , Issue.22-24 , pp. 2986-3008
    • Espin, J.C.1    Garcia-Conesa, M.T.2    Tomas-Barberan, F.A.3
  • 11
    • 84906762112 scopus 로고    scopus 로고
    • Metabolite Profiling of Red and White Pitayas (Hylocereus polyrhizus and Hylocereus undatus) for Comparing Betalain Biosynthesis and Antioxidant Activity
    • PMID: WOS:000340992100029
    • Suh DH, Lee S, Heo DY, Kim YS, Cho SK, Lee S, et al. Metabolite Profiling of Red and White Pitayas (Hylocereus polyrhizus and Hylocereus undatus) for Comparing Betalain Biosynthesis and Antioxidant Activity. J Agr Food Chem. 2014; 62(34):8764-71. doi: 10.1021/jf5020704 PMID: WOS:000340992100029.
    • (2014) J Agr Food Chem , vol.62 , Issue.34 , pp. 8764-8771
    • Suh, D.H.1    Lee, S.2    Heo, D.Y.3    Kim, Y.S.4    Cho, S.K.5    Lee, S.6
  • 12
    • 36148965173 scopus 로고    scopus 로고
    • Phenolic compound profiles and their corresponding antioxidant capacity of purple pitaya (Hylocereus sp.) genotypes
    • PMID: WOS:000251331700003
    • Esquivel P, Stintzing FC, Carle R. Phenolic compound profiles and their corresponding antioxidant capacity of purple pitaya (Hylocereus sp.) genotypes. Z Naturforsch C. 2007; 62(9-10):636-44. PMID: WOS:000251331700003.
    • (2007) Z Naturforsch C , vol.62 , Issue.9-10 , pp. 636-644
    • Esquivel, P.1    Stintzing, F.C.2    Carle, R.3
  • 14
    • 0037048769 scopus 로고    scopus 로고
    • Fruit flesh betacyanin pigments in Hylocereus cacti
    • PMID: WOS:000178501300048
    • Wybraniec S, Mizrahi Y. Fruit flesh betacyanin pigments in Hylocereus cacti. J Agr Food Chem. 2002; 50(21):6086-9. doi: 10.1021/jf020145k PMID: WOS:000178501300048.
    • (2002) J Agr Food Chem , vol.50 , Issue.21 , pp. 6086-6089
    • Wybraniec, S.1    Mizrahi, Y.2
  • 15
    • 84970873616 scopus 로고    scopus 로고
    • EFFECTS OF RED PITAYA FRUIT (HYLOCEREUS POLYRHIZUS) CONSUMPTION ON BLOOD GLUCOSE LEVEL AND LIPID PROFILE IN TYPE 2 DIABETIC SUBJECTS
    • Abd Hadi N, Mohamad M, Rohin MAK, Mohd Yusof R. EFFECTS OF RED PITAYA FRUIT (HYLOCEREUS POLYRHIZUS) CONSUMPTION ON BLOOD GLUCOSE LEVEL AND LIPID PROFILE IN TYPE 2 DIABETIC SUBJECTS. Borneo Science Journal. 2012; 31(2):113-29.
    • (2012) Borneo Science Journal , vol.31 , Issue.2 , pp. 113-129
    • Abd Hadi, N.1    Mohamad, M.2    Rohin, M.A.K.3    Mohd Yusof, R.4
  • 16
    • 84970872356 scopus 로고    scopus 로고
    • Hypocholesterolemic Effect of Fermented Red Pitaya (Hylocereus Polyrhizus) Juice in Diet-Induced Hypercholesterolemic Rats
    • PMID: WOS:000270827200344
    • Yusof RM, Akhiruddin MA. Hypocholesterolemic Effect of Fermented Red Pitaya (Hylocereus Polyrhizus) Juice in Diet-Induced Hypercholesterolemic Rats. Ann Nutr Metab. 2009; 55:92-. PMID: WOS:000270827200344.
    • (2009) Ann Nutr Metab , vol.55 , pp. 92
    • Yusof, R.M.1    Akhiruddin, M.A.2
  • 17
    • 84914170492 scopus 로고    scopus 로고
    • Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit
    • PMID: WOS:000345701500023
    • Omidizadeh A, Yusof RM, Roohinejad S, Ismail A, Abu Bakar MZ, Bekhit AEA. Anti-diabetic activity of red pitaya (Hylocereus polyrhizus) fruit. Rsc Adv. 2014; 4(108):62978-86. doi: 10.1039/c4ra10789f PMID: WOS:000345701500023.
    • (2014) Rsc Adv , vol.4 , Issue.108 , pp. 62978-62986
    • Omidizadeh, A.1    Yusof, R.M.2    Roohinejad, S.3    Ismail, A.4    Abu Bakar, M.Z.5    Bekhit, A.E.A.6
  • 18
    • 84904738318 scopus 로고    scopus 로고
    • Effects of red pitaya juice supplementation on cardiovascular and hepatic changes in high-carbohydrate, high-fat diet-induced metabolic syndrome rats
    • PMID: WOS:000338162800001
    • Ramli NS, Brown L, Ismail P, Rahmat A. Effects of red pitaya juice supplementation on cardiovascular and hepatic changes in high-carbohydrate, high-fat diet-induced metabolic syndrome rats. Bmc Complem Altern M. 2014; 14. Artn 189 10.1186/1472-6882-14-189. PMID: WOS:000338162800001.
    • (2014) Bmc Complem Altern M , vol.14
    • Ramli, N.S.1    Brown, L.2    Ismail, P.3    Rahmat, A.4
  • 19
    • 0031790242 scopus 로고    scopus 로고
    • Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent
    • PMID: WOS:000079431900014
    • Singleton VL, Orthofer R, Lamuela-Raventos RM. Analysis of total phenols and other oxidation substrates and antioxidants by means of Folin-Ciocalteu reagent. Methods Enzymol. 1999; 299:152-78. PMID: WOS:000079431900014.
    • (1999) Methods Enzymol , vol.299 , pp. 152-178
    • Singleton, V.L.1    Orthofer, R.2    Lamuela-Raventos, R.M.3
  • 20
    • 11144283509 scopus 로고    scopus 로고
    • Determination of the total phenolic, flavonoid and proline contents in Burkina Fasan honey, as well as their radical scavenging activity
    • PMID: WOS:000226920500024
    • Meda A, Lamien CE, Romito M, Millogo J, Nacoulma OG. Determination of the total phenolic, flavonoid and proline contents in Burkina Fasan honey, as well as their radical scavenging activity. Food Chem. 2005; 91(3):571-7. doi: 10.1016/j.foochem.2004.10.006 PMID: WOS:000226920500024.
    • (2005) Food Chem , vol.91 , Issue.3 , pp. 571-577
    • Meda, A.1    Lamien, C.E.2    Romito, M.3    Millogo, J.4    Nacoulma, O.G.5
  • 21
    • 70449158340 scopus 로고
    • A simple method for the isolation and purification of total lipides from animal tissues
    • PMID: 13428781
    • Folch J, Lees M, Sloane Stanley GH. A simple method for the isolation and purification of total lipides from animal tissues. The Journal of biological chemistry. 1957; 226(1):497-509. PMID: 13428781.
    • (1957) The Journal of Biological Chemistry , vol.226 , Issue.1 , pp. 497-509
    • Folch, J.1    Lees, M.2    Sloane Stanley, G.H.3
  • 22
    • 20044374023 scopus 로고    scopus 로고
    • Design and validation of a histological scoring system for nonalcoholic fatty liver disease
    • PMID: 15915461
    • Kleiner DE, Brunt EM, Van Natta M, Behling C, Contos MJ, Cummings OW, et al. Design and validation of a histological scoring system for nonalcoholic fatty liver disease. Hepatology. 2005; 41(6):1313-21. doi: 10.1002/hep.20701 PMID: 15915461.
    • (2005) Hepatology , vol.41 , Issue.6 , pp. 1313-1321
    • Kleiner, D.E.1    Brunt, E.M.2    Van Natta, M.3    Behling, C.4    Contos, M.J.5    Cummings, O.W.6
  • 23
    • 46749119854 scopus 로고    scopus 로고
    • Altered hyperlipidemia, hepatic steatosis, and hepatic peroxisome proliferator-activated receptors in rats with intake of tart cherry
    • PMID: WOS:000257633800008
    • Seymour EM, Singer AAM, Kirakosyan A, Urcuyo-Llanes DE, Kaufman PB, Bolling SF. Altered hyperlipidemia, hepatic steatosis, and hepatic peroxisome proliferator-activated receptors in rats with intake of tart cherry. J Med Food. 2008; 11(2):252-9. doi: 10.1089/jmf.2007.658 PMID: WOS:000257633800008.
    • (2008) J Med Food , vol.11 , Issue.2 , pp. 252-259
    • Seymour, E.M.1    Singer, A.A.M.2    Kirakosyan, A.3    Urcuyo-Llanes, D.E.4    Kaufman, P.B.5    Bolling, S.F.6
  • 24
    • 79957867318 scopus 로고    scopus 로고
    • Anthocyanins: Natural Colorants with Health-Promoting Properties
    • PMID: WOS:000278069300008
    • He JA, Giusti MM. Anthocyanins: Natural Colorants with Health-Promoting Properties. Annu Rev Food Sci T. 2010; 1:163-87. doi: 10.1146/annurev.food.080708.100754 PMID: WOS:000278069300008.
    • (2010) Annu Rev Food Sci T , vol.1 , pp. 163-187
    • He, J.A.1    Giusti, M.M.2
  • 25
    • 84884389488 scopus 로고    scopus 로고
    • Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: Therapeutic implications for diabetes and its cardiovascular complications
    • PMID: WOS:000324751900001
    • Munir KM, Chandrasekaran S, Gao F, Quon MJ. Mechanisms for food polyphenols to ameliorate insulin resistance and endothelial dysfunction: therapeutic implications for diabetes and its cardiovascular complications. Am J Physiol-Endoc M. 2013; 305(6):E679-E86. doi: 10.1152/ajpendo.00377.2013 PMID: WOS:000324751900001.
    • (2013) Am J Physiol-Endoc M , vol.305 , Issue.6 , pp. E679-E686
    • Munir, K.M.1    Chandrasekaran, S.2    Gao, F.3    Quon, M.J.4
  • 26
    • 84880349078 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol in obesity and type 2 diabetes: New avenues for health benefits?
    • PMID: WOS:000326091100010
    • Timmers S, Hesselink MKC, Schrauwen P. Therapeutic potential of resveratrol in obesity and type 2 diabetes: new avenues for health benefits? Ann Ny Acad Sci. 2013; 1290:83-9. doi: 10.1111/nyas.12185 PMID: WOS:000326091100010.
    • (2013) Ann Ny Acad Sci , vol.1290 , pp. 83-89
    • Timmers, S.1    Hesselink, M.K.C.2    Schrauwen, P.3
  • 27
    • 33745106645 scopus 로고    scopus 로고
    • Drug Insight: The role of leptin in human physiology and pathophysiology - Emerging clinical applications
    • PMID: 16932309
    • Brennan AM, Mantzoros CS. Drug Insight: the role of leptin in human physiology and pathophysiology - emerging clinical applications. Nature clinical practice Endocrinology & metabolism. 2006; 2(6):318-27. doi: 10.1038/ncpendmet0196 PMID: 16932309.
    • (2006) Nature Clinical Practice Endocrinology & Metabolism , vol.2 , Issue.6 , pp. 318-327
    • Brennan, A.M.1    Mantzoros, C.S.2
  • 28
    • 25844457693 scopus 로고    scopus 로고
    • Obesity
    • PMID: 16198769
    • Haslam DW, James WP. Obesity. Lancet. 2005; 366(9492):1197-209. doi: 10.1016/S0140-6736(05)67483-1 PMID: 16198769.
    • (2005) Lancet , vol.366 , Issue.9492 , pp. 1197-1209
    • Haslam, D.W.1    James, W.P.2
  • 30
    • 11144264156 scopus 로고    scopus 로고
    • Nonalcoholic Fatty Liver Disease: A Review of Current Understanding and Future Impact
    • PMID: WOS:000208072400003
    • Charlton M. Nonalcoholic Fatty Liver Disease: A Review of Current Understanding and Future Impact. Clin Gastroenterol H. 2004; 2(12):1048-58. doi: 10.1053/S1542-3565(04)00440-9 PMID: WOS:000208072400003.
    • (2004) Clin Gastroenterol H , vol.2 , Issue.12 , pp. 1048-1058
    • Charlton, M.1
  • 31
    • 0034648794 scopus 로고    scopus 로고
    • CAP defines a second signalling pathway required for insulin-stimulated glucose transport
    • PMID: WOS:000089241000052
    • Baumann CA, Ribon V, Kanzaki M, Thurmond DC, Mora S, Shigematsu S, et al. CAP defines a second signalling pathway required for insulin-stimulated glucose transport. Nature. 2000; 407(6801):202-7. PMID: WOS:000089241000052.
    • (2000) Nature , vol.407 , Issue.6801 , pp. 202-207
    • Baumann, C.A.1    Ribon, V.2    Kanzaki, M.3    Thurmond, D.C.4    Mora, S.5    Shigematsu, S.6
  • 32
    • 84874672042 scopus 로고    scopus 로고
    • A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome
    • PMID: WOS:000315456700005
    • Auinger A, Rubin D, Sabandal M, Helwig U, Ruther A, Schreiber S, et al. A common haplotype of carnitine palmitoyltransferase 1b is associated with the metabolic syndrome. Brit J Nutr. 2013; 109(5):810-5. doi: 10.1017/S0007114512002656 PMID: WOS:000315456700005.
    • (2013) Brit J Nutr , vol.109 , Issue.5 , pp. 810-815
    • Auinger, A.1    Rubin, D.2    Sabandal, M.3    Helwig, U.4    Ruther, A.5    Schreiber, S.6
  • 33
    • 0037162719 scopus 로고    scopus 로고
    • Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER
    • PMID: WOS:000177653200010
    • Yang T, Espenshade PJ, Wright ME, Yabe D, Gong Y, Aebersold R, et al. Crucial step in cholesterol homeostasis: Sterols promote binding of SCAP to INSIG-1, a membrane protein that facilitates retention of SREBPs in ER. Cell. 2002; 110(4):489-500. doi: 10.1016/S0092-8674(02)00872-3 PMID: WOS:000177653200010.
    • (2002) Cell , vol.110 , Issue.4 , pp. 489-500
    • Yang, T.1    Espenshade, P.J.2    Wright, M.E.3    Yabe, D.4    Gong, Y.5    Aebersold, R.6
  • 34
    • 0036460675 scopus 로고    scopus 로고
    • Lipoprotein lipase: Structure, function, regulation, and role in disease
    • PMID: WOS:000180587300004
    • Mead JR, Irvine SA, Ramji DP. Lipoprotein lipase: structure, function, regulation, and role in disease. J Mol Med-Jmm. 2002; 80(12):753-69. doi: 10.1007/s00109-002-0384-9 PMID: WOS:000180587300004.
    • (2002) J Mol Med-Jmm , vol.80 , Issue.12 , pp. 753-769
    • Mead, J.R.1    Irvine, S.A.2    Ramji, D.P.3
  • 35
    • 84879469292 scopus 로고    scopus 로고
    • Mulberry anthocyanins inhibit oleic acid induced lipid accumulation by reduction of lipogenesis and promotion of hepatic lipid clearance
    • Chang J-J, Hsu M-J, Huang H-P, Chung D-J, Chang Y-C, Wang C-J. Mulberry anthocyanins inhibit oleic acid induced lipid accumulation by reduction of lipogenesis and promotion of hepatic lipid clearance. J Agr Food Chem. 2013; 61(25):6069-76.
    • (2013) J Agr Food Chem , vol.61 , Issue.25 , pp. 6069-6076
    • Chang, J.-J.1    Hsu, M.-J.2    Huang, H.-P.3    Chung, D.-J.4    Chang, Y.-C.5    Wang, C.-J.6
  • 36
    • 34848912627 scopus 로고    scopus 로고
    • Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia
    • PMID: 17823788
    • Cani PD, Neyrinck AM, Fava F, Knauf C, Burcelin RG, Tuohy KM, et al. Selective increases of bifidobacteria in gut microflora improve high-fat-diet-induced diabetes in mice through a mechanism associated with endotoxaemia. Diabetologia. 2007; 50(11):2374-83. doi: 10.1007/s00125-007-0791-0 PMID: 17823788.
    • (2007) Diabetologia , vol.50 , Issue.11 , pp. 2374-2383
    • Cani, P.D.1    Neyrinck, A.M.2    Fava, F.3    Knauf, C.4    Burcelin, R.G.5    Tuohy, K.M.6
  • 37
    • 34347399563 scopus 로고    scopus 로고
    • Metabolic endotoxemia initiates obesity and insulin resistance
    • PMID: 17456850
    • Cani PD, Amar J, Iglesias MA, Poggi M, Knauf C, Bastelica D, et al. Metabolic endotoxemia initiates obesity and insulin resistance. Diabetes. 2007; 56(7):1761-72. doi: 10.2337/db06-1491 PMID: 17456850.
    • (2007) Diabetes , vol.56 , Issue.7 , pp. 1761-1772
    • Cani, P.D.1    Amar, J.2    Iglesias, M.A.3    Poggi, M.4    Knauf, C.5    Bastelica, D.6
  • 38
    • 0030253348 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus
    • PMID: WOS:A1996VR07100003
    • Kruszynska YT, Olefsky JM. Cellular and molecular mechanisms of non-insulin dependent diabetes mellitus. J Invest Med. 1996; 44(8):413-28. PMID: WOS:A1996VR07100003.
    • (1996) J Invest Med , vol.44 , Issue.8 , pp. 413-428
    • Kruszynska, Y.T.1    Olefsky, J.M.2
  • 39
    • 0026021161 scopus 로고
    • Insulin Resistance - A Multifaceted Syndrome Responsible for Niddm, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular-Disease
    • PMID: WOS:A1991EZ64800001
    • Defronzo RA, Ferrannini E. Insulin Resistance - a Multifaceted Syndrome Responsible for Niddm, Obesity, Hypertension, Dyslipidemia, and Atherosclerotic Cardiovascular-Disease. Diabetes Care. 1991; 14(3):173-94. doi: 10.2337/diacare.14.3.173 PMID: WOS:A1991EZ64800001.
    • (1991) Diabetes Care , vol.14 , Issue.3 , pp. 173-194
    • Defronzo, R.A.1    Ferrannini, E.2
  • 40
    • 0034697846 scopus 로고    scopus 로고
    • Identification of a novel FGF, FGF-21, preferentially expressed in the liver
    • PMID: WOS:000087924000024
    • Nishimura T, Nakatake Y, Konishi M, Itoh N. Identification of a novel FGF, FGF-21, preferentially expressed in the liver. Bba-Gene Struct Expr. 2000; 1492(1):203-6. doi: 10.1016/S0167-4781(00)00067-1 PMID: WOS:000087924000024.
    • (2000) Bba-Gene Struct Expr , vol.1492 , Issue.1 , pp. 203-206
    • Nishimura, T.1    Nakatake, Y.2    Konishi, M.3    Itoh, N.4
  • 42
    • 61649127208 scopus 로고    scopus 로고
    • Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice
    • PMID: WOS:000262187100037
    • Xu J, Lloyd DJ, Hale C, Stanislaus S, Chen M, Sivits G, et al. Fibroblast Growth Factor 21 Reverses Hepatic Steatosis, Increases Energy Expenditure, and Improves Insulin Sensitivity in Diet-Induced Obese Mice. Diabetes. 2009; 58(1):250-9. doi: 10.2337/db08-0392 PMID: WOS:000262187100037.
    • (2009) Diabetes , vol.58 , Issue.1 , pp. 250-259
    • Xu, J.1    Lloyd, D.J.2    Hale, C.3    Stanislaus, S.4    Chen, M.5    Sivits, G.6
  • 43
    • 68149091653 scopus 로고    scopus 로고
    • Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance
    • PMID: WOS:000268687800037
    • Chavez AO, Molina-Carrion M, Abdul-Ghani MA, Folli F, DeFronzo RA, Tripathy D. Circulating Fibroblast Growth Factor-21 Is Elevated in Impaired Glucose Tolerance and Type 2 Diabetes and Correlates With Muscle and Hepatic Insulin Resistance. Diabetes Care. 2009; 32(8):1542-6. doi: 10.2337/dc09-0684 PMID: WOS:000268687800037.
    • (2009) Diabetes Care , vol.32 , Issue.8 , pp. 1542-1546
    • Chavez, A.O.1    Molina-Carrion, M.2    Abdul-Ghani, M.A.3    Folli, F.4    DeFronzo, R.A.5    Tripathy, D.6
  • 44
    • 48349146527 scopus 로고    scopus 로고
    • Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans
    • PMID: WOS:000255628700014
    • Zhang X, Yeung DCY, Karpisek M, Stejskal D, Zhou ZG, Liu F, et al. Serum FGF21 levels are increased in obesity and are independently associated with the metabolic syndrome in humans. Diabetes. 2008; 57(5):1246-53. doi: 10.2337/db07-1476 PMID: WOS:000255628700014.
    • (2008) Diabetes , vol.57 , Issue.5 , pp. 1246-1253
    • Zhang, X.1    Yeung, D.C.Y.2    Karpisek, M.3    Stejskal, D.4    Zhou, Z.G.5    Liu, F.6
  • 45
    • 84863814092 scopus 로고    scopus 로고
    • Metabolic actions of fibroblast growth factor 21
    • PMID: WOS:000306372200015
    • Cuevas-Ramos D, Aguilar-Salinas CA, Gomez-Perez FJ. Metabolic actions of fibroblast growth factor 21. Curr Opin Pediatr. 2012; 24(4):523-9. doi: 10.1097/MOP.0b013e3283557d22 PMID: WOS:000306372200015.
    • (2012) Curr Opin Pediatr , vol.24 , Issue.4 , pp. 523-529
    • Cuevas-Ramos, D.1    Aguilar-Salinas, C.A.2    Gomez-Perez, F.J.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.