Visfatin attenuates the ox-LDL-induced senescence of endothelial progenitor cells by upregulating SIRT1 expression through the PI3K/Akt/ERK pathway

International Journal of Molecular Medicine

Volumn 38, Issue 2, 2016, Pages 643-649

  Ming, Guang Feng ^a   Tang, Yong Jun ^b   Hu, Kai ^b   Chen, Yao ^b   Huang, Wei Hua ^b   Xiao, Jian ^a  

^a CENTRAL SOUTH UNIVERSITY   (China)

^b Clinical Pharmacology ^*  (China)

Author keywords

Endothelial progenitor cells; PI3K Akt ERK pathway; Senescence; Sirtuin 1; Visfatin

Indexed keywords

BETA GALACTOSIDASE; LOW DENSITY LIPOPROTEIN; MESSENGER RNA; MITOGEN ACTIVATED PROTEIN KINASE; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE B; PROTEIN P53; SIRTUIN 1; TELOMERASE; OXIDIZED LOW DENSITY LIPOPROTEIN;

ARTICLE; CELL AGING; CONTROLLED STUDY; ENDOTHELIAL PROGENITOR CELL; ENZYME ACTIVITY; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; GENE; GENE EXPRESSION; HUMAN; HUMAN CELL; INTRACELLULAR SIGNALING; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; SENESCENCE; SIRT1 GENE; UPREGULATION; WESTERN BLOTTING; CYTOLOGY; DRUG EFFECTS; GENETICS; METABOLISM; SIGNAL TRANSDUCTION;

CELL AGING; ENDOTHELIAL PROGENITOR CELLS; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; HUMANS; LIPOPROTEINS, LDL; NICOTINAMIDE PHOSPHORIBOSYLTRANSFERASE; PHOSPHATIDYLINOSITOL 3-KINASES; PROTO-ONCOGENE PROTEINS C-AKT; SIGNAL TRANSDUCTION; SIRTUIN 1; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84978859509     PISSN: 11073756     EISSN: 1791244X     Source Type: Journal    
DOI: 10.3892/ijmm.2016.2633     Document Type: Article

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