Mechanism of TRIM25 Catalytic Activation in the Antiviral RIG-I Pathway

Cell Reports

Volumn 16, Issue 5, 2016, Pages 1315-1325

  Sanchez, Jacint G ^a   Chiang, Jessica J ^b   Sparrer, Konstantin M J ^c   Alam, Steven L ^d   Chi, Michael ^a   Roganowicz, Marcin D ^a   Sankaran, Banumathi ^e   Gack, Michaela U ^b,c   Pornillos, Owen ^a  

^a UNIVERSITY OF VIRGINIA   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c UNIVERSITY OF CHICAGO   (United States)

^d UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^e LAWRENCE BERKELEY NATIONAL LABORATORY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

PROTEIN TRIM25; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; ANTIVIRUS AGENT; DDX58 PROTEIN, HUMAN; INTERFERON; PROTEIN BINDING; RETINOIC ACID INDUCIBLE PROTEIN I; TRANSCRIPTION FACTOR; TRIM25 PROTEIN, HUMAN; TRIPARTITE MOTIF PROTEIN; UBIQUITIN PROTEIN LIGASE;

ANTIVIRAL ACTIVITY; ARTICLE; CONTROLLED STUDY; DIMERIZATION; ENZYME ACTIVITY; HUMAN; HUMAN CELL; IN VITRO STUDY; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; PROTEIN DOMAIN; PROTEIN FUNCTION; PROTEIN MOTIF; PROTEIN STRUCTURE; SIGNAL TRANSDUCTION; UBIQUITINATION; CATALYSIS; CELL LINE; HEK293 CELL LINE; METABOLISM; PHYSIOLOGY;

ANTIVIRAL AGENTS; CATALYSIS; CELL LINE; DEAD BOX PROTEIN 58; DIMERIZATION; HEK293 CELLS; HUMANS; INTERFERONS; PROTEIN BINDING; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRIPARTITE MOTIF PROTEINS; UBIQUITIN-PROTEIN LIGASES; UBIQUITINATION;

EID: 84978807214     PISSN: None     EISSN: 22111247     Source Type: Journal    
DOI: 10.1016/j.celrep.2016.06.070     Document Type: Article

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