Structural studies of postentry restriction factors reveal antiparallel dimers that enable avid binding to the HIV-1 capsid lattice

Proceedings of the National Academy of Sciences of the United States of America

Volumn 111, Issue 26, 2014, Pages 9609-9614

  Goldstone, David C ^a,b,c   Walker, Philip A ^a   Calder, Lesley J ^d   Coombs, Peter J ^a   Kirkpatrick, Joshua ^b,c   Ball, Neil J ^a   Hilditch, Laura ^e   Yap, Melvyn W ^e   Rosenthal, Peter B ^d   Stoye, Jonathan P ^e,f   Taylor, Ian A ^a  

^a UNIVERSITY OF AUCKLAND   (New Zealand)

^b UNIVERSITY OF AUCKLAND   (New Zealand)

^c UNIVERSITY COLLEGE LONDON   (United Kingdom)

^d Physical Biochemistry   (United Kingdom)

^e NATIONAL INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^f IMPERIAL COLLEGE LONDON   (United Kingdom)

Author keywords

MLV; Retrovirus; SAXS; X ray crystallography

Indexed keywords

BINDING PROTEIN; DIMER; MONOMER;

ARTICLE; CRYSTAL STRUCTURE; DIMERIZATION; HOST RESISTANCE; HUMAN IMMUNODEFICIENCY VIRUS 1; HYBRID; MOLECULAR MECHANICS; MOLECULAR RECOGNITION; MOLECULE; NONHUMAN; PRIORITY JOURNAL; PROTEIN INTERACTION; RETROVIRUS INFECTION; VIRUS CAPSID; X RAY CRYSTALLOGRAPHY;

MLV; RETROVIRUS; SAXS; X-RAY CRYSTALLOGRAPHY;

AMINO ACID SEQUENCE; ANIMALS; BACTERIOPHAGE T4; BASE SEQUENCE; CAPSID; CHROMATOGRAPHY, GEL; CRYSTALLIZATION; DIMERIZATION; ESCHERICHIA COLI; HIV-1; LINEAR MODELS; MACACA MULATTA; MICROSCOPY, ELECTRON; MODELS, MOLECULAR; MOLECULAR SEQUENCE DATA; MURAMIDASE; PROTEIN CONFORMATION; PROTEINS; RECOMBINANT FUSION PROTEINS; SCATTERING, SMALL ANGLE; SEQUENCE ANALYSIS, DNA; SURFACE PLASMON RESONANCE; VIRUS INTERNALIZATION; X-RAY DIFFRACTION;

EID: 84903694269     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1402448111     Document Type: Article

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