An NK Cell Perforin Response Elicited via IL-18 Controls Mucosal Inflammation Kinetics during Salmonella Gut Infection

PLoS Pathogens

Volumn 12, Issue 6, 2016, Pages

  Müller, Anna A ^a   Dolowschiak, Tamas ^a   Sellin, Mikael E ^a,b   Felmy, Boas ^a   Verbree, Carolin ^a   Gadient, Sandra ^a   Westermann, Alexander J ^c   Vogel, Jörg ^c   LeibundGut Landmann, Salome ^d   Hardt, Wolf Dietrich ^a  

^a ETH ZURICH   (Switzerland)

^b UPPSALA UNIVERSITY   (Sweden)

^c UNIVERSITY OF WÜRZBURG   (Germany)

^d UNIVERSITY OF ZURICH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

INFLAMMASOME; INTERLEUKIN 18; INTERLEUKIN 1BETA CONVERTING ENZYME; PERFORIN; VIRULENCE FACTOR; PERFORIN, MOUSE; PORE FORMING CYTOTOXIC PROTEIN;

ANIMAL CELL; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BACTERIAL VIRULENCE; CELL ISOLATION; CELL MIGRATION; CONFOCAL MICROSCOPY; CONTROLLED STUDY; DIARRHEA; ENTEROPATHY; FLOW CYTOMETRY; HISTOPATHOLOGY; IMMUNE RESPONSE; LAMINA PROPRIA; MUCOSA INFLAMMATION; NATURAL KILLER CELL; NONHUMAN; POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALMONELLA ENTERICA SEROVAR TYPHIMURIUM; SALMONELLOSIS; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; DISEASE MODEL; IMMUNOLOGY; INFLAMMATION; INNATE IMMUNITY; INTESTINE MUCOSA; KINETICS; KNOCKOUT MOUSE; MOUSE; NEUTROPHIL CHEMOTAXIS;

ANIMALS; CASPASE 1; CHEMOTAXIS, LEUKOCYTE; DISEASE MODELS, ANIMAL; FLOW CYTOMETRY; IMMUNITY, INNATE; INFLAMMASOMES; INFLAMMATION; INTERLEUKIN-18; INTESTINAL MUCOSA; KILLER CELLS, NATURAL; KINETICS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; MICROSCOPY, CONFOCAL; POLYMERASE CHAIN REACTION; PORE FORMING CYTOTOXIC PROTEINS; SALMONELLA INFECTIONS; SALMONELLA TYPHIMURIUM;

EID: 84978796164     PISSN: 15537366     EISSN: 15537374     Source Type: Journal    
DOI: 10.1371/journal.ppat.1005723     Document Type: Article

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