Lack of the programmed death-1 receptor renders host susceptible to enteric microbial infection through impairing the production of the mucosal natural killer cell effector molecules

Journal of Leukocyte Biology

Volumn 99, Issue 3, 2016, Pages 475-482

  Solaymani Mohammadi, Shahram ^a   Lakhdari, Omar ^a   Minev, Ivelina ^a   Shenouda, Steve ^a   Frey, Blake F ^b   Billeskov, Rolf ^b   Singer, Steven M ^c   Berzofsky, Jay A ^b   Eckmann, Lars ^a   Kagnoff, Martin F ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

^b NATIONAL CANCER INSTITUTE   (United States)

^c GEORGETOWN UNIVERSITY   (United States)

Author keywords

Attaching effacing bacteria; Citrobacter rodentium; Granzyme B; PD 1; Perforin

Indexed keywords

ANTIBODY; CD11B ANTIGEN; GLYCOPROTEIN P 15095; GRANZYME B; PERFORIN; PROGRAMMED DEATH 1 ANTIBODY; PROGRAMMED DEATH 1 RECEPTOR; UNCLASSIFIED DRUG; GAMMA INTERFERON; GRANZYME; GZMB PROTEIN, MOUSE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CITROBACTER RODENTIUM; CONTROLLED STUDY; DENDRITIC CELL; ENTERIC MICROBIAL INFECTION; FEMALE; HOST; INFECTION; INTESTINE; INTESTINE INFECTION; INTESTINE MUCOSA; MACROPHAGE; MALE; MOUSE; NATURAL KILLER CELL; NATURAL KILLER T CELL; NONHUMAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; WILD TYPE; ANIMAL; BIOSYNTHESIS; C57BL MOUSE; COLON; ENTEROBACTERIACEAE INFECTION; IMMUNOLOGY; PHYSIOLOGY; SIGNAL TRANSDUCTION;

ANIMALS; CITROBACTER RODENTIUM; COLON; ENTEROBACTERIACEAE INFECTIONS; FEMALE; GRANZYMES; INTERFERON-GAMMA; INTESTINAL MUCOSA; KILLER CELLS, NATURAL; MALE; MICE; MICE, INBRED C57BL; PERFORIN; PROGRAMMED CELL DEATH 1 RECEPTOR; SIGNAL TRANSDUCTION;

EID: 84961250343     PISSN: 07415400     EISSN: 19383673     Source Type: Journal    
DOI: 10.1189/jlb.4A0115-003RR     Document Type: Article

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