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Volumn 56, Issue 7, 2017, Pages 2265-2275

No effects of quercetin from onion skin extract on serum leptin and adiponectin concentrations in overweight-to-obese patients with (pre-)hypertension: a randomized double-blinded, placebo-controlled crossover trial

Author keywords

Adipocytokines; Human study; Metabolic syndrome; Quercetin

Indexed keywords

'ALLIUM CEPA'; ADIPONECTIN; C REACTIVE PROTEIN; GLUCOSE; HEMOGLOBIN A1C; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; INSULIN; LEPTIN; LOW DENSITY LIPOPROTEIN CHOLESTEROL; PLACEBO; QUERCETIN; TRIACYLGLYCEROL; TUMOR NECROSIS FACTOR; URIC ACID; BIOLOGICAL MARKER; CHOLESTEROL; GLYCOSYLATED HEMOGLOBIN; PLANT EXTRACT;

EID: 84978791289     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-016-1267-0     Document Type: Article
Times cited : (50)

References (65)
  • 1
    • 73449130797 scopus 로고    scopus 로고
    • C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis
    • Kaptoge S, Di AE, Lowe G, Pepys MB, Thompson SG, Collins R, Danesh J (2010) C-reactive protein concentration and risk of coronary heart disease, stroke, and mortality: an individual participant meta-analysis. Lancet 375:132–140
    • (2010) Lancet , vol.375 , pp. 132-140
    • Kaptoge, S.1    Di, A.E.2    Lowe, G.3    Pepys, M.B.4    Thompson, S.G.5    Collins, R.6    Danesh, J.7
  • 2
    • 59649120641 scopus 로고    scopus 로고
    • C-reactive protein: eighty years from discovery to emergence as a major risk marker for cardiovascular disease
    • COI: 1:CAS:528:DC%2BD1MXhvVWksrk%3D
    • Ridker PM (2009) C-reactive protein: eighty years from discovery to emergence as a major risk marker for cardiovascular disease. Clin Chem 55:209–215
    • (2009) Clin Chem , vol.55 , pp. 209-215
    • Ridker, P.M.1
  • 3
    • 19944389573 scopus 로고    scopus 로고
    • A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes
    • COI: 1:CAS:528:DC%2BD2MXlsFyhtL4%3D
    • Shai I, Schulze MB, Manson JE, Rexrode KM, Stampfer MJ, Mantzoros C, Hu FB (2005) A prospective study of soluble tumor necrosis factor-alpha receptor II (sTNF-RII) and risk of coronary heart disease among women with type 2 diabetes. Diabetes Care 28:1376–1382
    • (2005) Diabetes Care , vol.28 , pp. 1376-1382
    • Shai, I.1    Schulze, M.B.2    Manson, J.E.3    Rexrode, K.M.4    Stampfer, M.J.5    Mantzoros, C.6    Hu, F.B.7
  • 5
    • 84898044515 scopus 로고    scopus 로고
    • Adipokines: a link between obesity and cardiovascular disease
    • Nakamura K, Fuster JJ, Walsh K (2014) Adipokines: a link between obesity and cardiovascular disease. J Cardiol 63:250–259
    • (2014) J Cardiol , vol.63 , pp. 250-259
    • Nakamura, K.1    Fuster, J.J.2    Walsh, K.3
  • 6
    • 12444304182 scopus 로고    scopus 로고
    • Adiponectin: action, regulation and association to insulin sensitivity
    • COI: 1:CAS:528:DC%2BD2MXhsVKlu74%3D
    • Lihn AS, Pedersen SB, Richelsen B (2005) Adiponectin: action, regulation and association to insulin sensitivity. Obes Rev 6:13–21
    • (2005) Obes Rev , vol.6 , pp. 13-21
    • Lihn, A.S.1    Pedersen, S.B.2    Richelsen, B.3
  • 7
    • 44449111714 scopus 로고    scopus 로고
    • Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans
    • COI: 1:CAS:528:DC%2BD1cXmslyisrw%3D
    • Swarbrick MM, Havel PJ (2008) Physiological, pharmacological, and nutritional regulation of circulating adiponectin concentrations in humans. Metab Syndr Relat Disord 6:87–102
    • (2008) Metab Syndr Relat Disord , vol.6 , pp. 87-102
    • Swarbrick, M.M.1    Havel, P.J.2
  • 9
    • 44949237971 scopus 로고    scopus 로고
    • Adiponectin and its association with insulin resistance and type 2 diabetes
    • COI: 1:CAS:528:DC%2BD1cXhtVGjsrvL
    • Sheng T, Yang K (2008) Adiponectin and its association with insulin resistance and type 2 diabetes. J Genet Genomics 35:321–326
    • (2008) J Genet Genomics , vol.35 , pp. 321-326
    • Sheng, T.1    Yang, K.2
  • 10
    • 46249112180 scopus 로고    scopus 로고
    • A novel role for adiponectin in the regulation of inflammation
    • COI: 1:CAS:528:DC%2BD1cXpslOitb4%3D
    • Ouchi N, Walsh K (2008) A novel role for adiponectin in the regulation of inflammation. Arterioscler Thromb Vasc Biol 28:1219–1221
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1219-1221
    • Ouchi, N.1    Walsh, K.2
  • 11
    • 33947627537 scopus 로고    scopus 로고
    • Adiponectin as an anti-inflammatory factor
    • COI: 1:CAS:528:DC%2BD2sXjslSlu7k%3D
    • Ouchi N, Walsh K (2007) Adiponectin as an anti-inflammatory factor. Clin Chim Acta 380:24–30
    • (2007) Clin Chim Acta , vol.380 , pp. 24-30
    • Ouchi, N.1    Walsh, K.2
  • 13
    • 46249092855 scopus 로고    scopus 로고
    • Adiponectin decreases C-reactive protein synthesis and secretion from endothelial cells: evidence for an adipose tissue-vascular loop
    • COI: 1:CAS:528:DC%2BD1cXmvFeht74%3D
    • Devaraj S, Torok N, Dasu MR, Samols D, Jialal I (2008) Adiponectin decreases C-reactive protein synthesis and secretion from endothelial cells: evidence for an adipose tissue-vascular loop. Arterioscler Thromb Vasc Biol 28:1368–1374
    • (2008) Arterioscler Thromb Vasc Biol , vol.28 , pp. 1368-1374
    • Devaraj, S.1    Torok, N.2    Dasu, M.R.3    Samols, D.4    Jialal, I.5
  • 14
    • 0034198919 scopus 로고    scopus 로고
    • Leptin: a multifunctional hormone
    • COI: 1:STN:280:DC%2BD3M%2FitVajsA%3D%3D
    • Huang L, Li C (2000) Leptin: a multifunctional hormone. Cell Res 10:81–92
    • (2000) Cell Res , vol.10 , pp. 81-92
    • Huang, L.1    Li, C.2
  • 15
    • 0032558725 scopus 로고    scopus 로고
    • Leptin and the regulation of body weight in mammals
    • COI: 1:CAS:528:DyaK1cXmvFOmsL0%3D
    • Friedman JM, Halaas JL (1998) Leptin and the regulation of body weight in mammals. Nature 395:763–770
    • (1998) Nature , vol.395 , pp. 763-770
    • Friedman, J.M.1    Halaas, J.L.2
  • 16
    • 84929990793 scopus 로고    scopus 로고
    • Differential role of leptin and adiponectin in cardiovascular system
    • COI: 1:STN:280:DC%2BC2MbisVyhsw%3D%3D
    • Ghantous CM, Azrak Z, Hanache S, Abou-Kheir W, Zeidan A (2015) Differential role of leptin and adiponectin in cardiovascular system. Int J Endocrinol 2015:534320
    • (2015) Int J Endocrinol , vol.2015 , pp. 534320
    • Ghantous, C.M.1    Azrak, Z.2    Hanache, S.3    Abou-Kheir, W.4    Zeidan, A.5
  • 17
    • 68149124472 scopus 로고    scopus 로고
    • Dietary phenolics: chemistry, bioavailability and effects on health
    • COI: 1:CAS:528:DC%2BD1MXptFGmsr8%3D
    • Crozier A, Jaganath IB, Clifford MN (2009) Dietary phenolics: chemistry, bioavailability and effects on health. Nat Prod Rep 26:1001–1043
    • (2009) Nat Prod Rep , vol.26 , pp. 1001-1043
    • Crozier, A.1    Jaganath, I.B.2    Clifford, M.N.3
  • 18
    • 84891821964 scopus 로고    scopus 로고
    • Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies
    • Wang X, Ouyang YY, Liu J, Zhao G (2013) Flavonoid intake and risk of CVD: a systematic review and meta-analysis of prospective cohort studies. Br J Nutr 111:1–11
    • (2013) Br J Nutr , vol.111 , pp. 1-11
    • Wang, X.1    Ouyang, Y.Y.2    Liu, J.3    Zhao, G.4
  • 20
    • 84865853940 scopus 로고    scopus 로고
    • Associations between flavonoids and cardiovascular disease incidence or mortality in European and US populations
    • Peterson JJ, Dwyer JT, Jacques PF, McCullough ML (2012) Associations between flavonoids and cardiovascular disease incidence or mortality in European and US populations. Nutr Rev 70:491–508
    • (2012) Nutr Rev , vol.70 , pp. 491-508
    • Peterson, J.J.1    Dwyer, J.T.2    Jacques, P.F.3    McCullough, M.L.4
  • 21
    • 43049176634 scopus 로고    scopus 로고
    • Health effects of quercetin: from antioxidant to nutraceutical
    • COI: 1:CAS:528:DC%2BD1cXls1Snt7o%3D
    • Boots AW, Haenen GR, Bast A (2008) Health effects of quercetin: from antioxidant to nutraceutical. Eur J Pharmacol 585:325–337
    • (2008) Eur J Pharmacol , vol.585 , pp. 325-337
    • Boots, A.W.1    Haenen, G.R.2    Bast, A.3
  • 22
    • 44649099599 scopus 로고    scopus 로고
    • In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers
    • COI: 1:CAS:528:DC%2BD1cXntlSrsLs%3D
    • Boots AW, Wilms LC, Swennen EL, Kleinjans JC, Bast A, Haenen GR (2008) In vitro and ex vivo anti-inflammatory activity of quercetin in healthy volunteers. Nutrition 24:703–710
    • (2008) Nutrition , vol.24 , pp. 703-710
    • Boots, A.W.1    Wilms, L.C.2    Swennen, E.L.3    Kleinjans, J.C.4    Bast, A.5    Haenen, G.R.6
  • 23
    • 77954761550 scopus 로고    scopus 로고
    • Quercetin enhances adiponectin secretion by a PPAR-gamma independent mechanism
    • COI: 1:CAS:528:DC%2BC3cXptVCntrk%3D
    • Wein S, Behm N, Petersen RK, Kristiansen K, Wolffram S (2010) Quercetin enhances adiponectin secretion by a PPAR-gamma independent mechanism. Eur J Pharm Sci 41:16–22
    • (2010) Eur J Pharm Sci , vol.41 , pp. 16-22
    • Wein, S.1    Behm, N.2    Petersen, R.K.3    Kristiansen, K.4    Wolffram, S.5
  • 25
    • 84944171066 scopus 로고    scopus 로고
    • Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial
    • Brüll V, Burak C, Stoffel-Wagner B, Wolffram S, Nickenig G, Muller C, Langguth P, Alteheld B, Fimmers R, Naaf S, Zimmermann BF, Stehle P, Egert S (2015) Effects of a quercetin-rich onion skin extract on 24 h ambulatory blood pressure and endothelial function in overweight-to-obese patients with (pre-)hypertension: a randomised double-blinded placebo-controlled cross-over trial. Br J Nutr 114:1263–1277
    • (2015) Br J Nutr , vol.114 , pp. 1263-1277
    • Brüll, V.1    Burak, C.2    Stoffel-Wagner, B.3    Wolffram, S.4    Nickenig, G.5    Muller, C.6    Langguth, P.7    Alteheld, B.8    Fimmers, R.9    Naaf, S.10    Zimmermann, B.F.11    Stehle, P.12    Egert, S.13
  • 27
    • 25144459980 scopus 로고    scopus 로고
    • The metabolic syndrome—a new worldwide definition
    • Alberti KG, Zimmet P, Shaw J (2005) The metabolic syndrome—a new worldwide definition. Lancet 366:1059–1062
    • (2005) Lancet , vol.366 , pp. 1059-1062
    • Alberti, K.G.1    Zimmet, P.2    Shaw, J.3
  • 28
    • 0031471298 scopus 로고    scopus 로고
    • Flavonoid intake of adults in a Bavarian subgroup of the national food consumption survey
    • COI: 1:CAS:528:DyaK1cXis1Snuw%3D%3D
    • Linseisen J, Radtke J, Wolfram G (1997) Flavonoid intake of adults in a Bavarian subgroup of the national food consumption survey. Z Ernahrungswiss 36:403–412
    • (1997) Z Ernahrungswiss , vol.36 , pp. 403-412
    • Linseisen, J.1    Radtke, J.2    Wolfram, G.3
  • 32
    • 85029621994 scopus 로고    scopus 로고
    • Higher plasma quercetin levels following oral administration of an onion skin extract compared with pure quercetin dihydrate in humans
    • Epub ahead of print
    • Burak C, Brüll V, Langguth P, Zimmermann BF, Stoffel-Wagner B, Sausen U, Stehle P, Wolffram S, Egert S (2015) Higher plasma quercetin levels following oral administration of an onion skin extract compared with pure quercetin dihydrate in humans. Eur J Nutr Oct 20, 1–11. [Epub ahead of print]
    • (2015) Eur J Nutr Oct , vol.20 , pp. 1-11
    • Burak, C.1    Brüll, V.2    Langguth, P.3    Zimmermann, B.F.4    Stoffel-Wagner, B.5    Sausen, U.6    Stehle, P.7    Wolffram, S.8    Egert, S.9
  • 33
    • 19944429836 scopus 로고    scopus 로고
    • Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on high blood pressure research
    • COI: 1:CAS:528:DC%2BD2cXhtFaiu7rI
    • Pickering TG, Hall JE, Appel LJ, Falkner BE, Graves J, Hill MN, Jones DW, Kurtz T, Sheps SG, Roccella EJ (2005) Recommendations for blood pressure measurement in humans and experimental animals: part 1: blood pressure measurement in humans: a statement for professionals from the Subcommittee of Professional and Public Education of the American Heart Association Council on high blood pressure research. Hypertension 45:142–161
    • (2005) Hypertension , vol.45 , pp. 142-161
    • Pickering, T.G.1    Hall, J.E.2    Appel, L.J.3    Falkner, B.E.4    Graves, J.5    Hill, M.N.6    Jones, D.W.7    Kurtz, T.8    Sheps, S.G.9    Roccella, E.J.10
  • 34
    • 0021813187 scopus 로고
    • Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man
    • COI: 1:CAS:528:DyaL2MXlslKnu7k%3D
    • Matthews DR, Hosker JP, Rudenski AS, Naylor BA, Treacher DF, Turner RC (1985) Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28:412–419
    • (1985) Diabetologia , vol.28 , pp. 412-419
    • Matthews, D.R.1    Hosker, J.P.2    Rudenski, A.S.3    Naylor, B.A.4    Treacher, D.F.5    Turner, R.C.6
  • 37
    • 84875550388 scopus 로고    scopus 로고
    • Metabolic risk susceptibility in men is partially related to adiponectin/leptin ratio
    • Vega GL, Grundy SM (2013) Metabolic risk susceptibility in men is partially related to adiponectin/leptin ratio. J Obes 2013:409679
    • (2013) J Obes , vol.2013 , pp. 409679
    • Vega, G.L.1    Grundy, S.M.2
  • 38
    • 34247159038 scopus 로고    scopus 로고
    • A novel index of insulin resistance determined from the homeostasis model assessment index and adiponectin levels in Japanese subjects
    • COI: 1:CAS:528:DC%2BD2sXksFWmu7Y%3D
    • Matsuhisa M, Yamasaki Y, Emoto M, Shimabukuro M, Ueda S, Funahashi T, Matsuzawa Y (2007) A novel index of insulin resistance determined from the homeostasis model assessment index and adiponectin levels in Japanese subjects. Diabetes Res Clin Pract 77:151–154
    • (2007) Diabetes Res Clin Pract , vol.77 , pp. 151-154
    • Matsuhisa, M.1    Yamasaki, Y.2    Emoto, M.3    Shimabukuro, M.4    Ueda, S.5    Funahashi, T.6    Matsuzawa, Y.7
  • 39
    • 49449084484 scopus 로고    scopus 로고
    • Tissue distribution of quercetin in pigs after long-term dietary supplementation
    • COI: 1:CAS:528:DC%2BD1cXovFWns70%3D
    • Bieger J, Cermak R, Blank R, de Boer VC, Hollman PC, Kamphues J, Wolffram S (2008) Tissue distribution of quercetin in pigs after long-term dietary supplementation. J Nutr 138:1417–1420
    • (2008) J Nutr , vol.138 , pp. 1417-1420
    • Bieger, J.1    Cermak, R.2    Blank, R.3    de Boer, V.C.4    Hollman, P.C.5    Kamphues, J.6    Wolffram, S.7
  • 40
    • 0023483161 scopus 로고
    • The analysis of data from 2 × 2 cross-over trials with baseline measurements
    • COI: 1:STN:280:DyaL1c7ksFWqug%3D%3D
    • Kenward MG, Jones B (1987) The analysis of data from 2 × 2 cross-over trials with baseline measurements. Stat Med 6:911–926
    • (1987) Stat Med , vol.6 , pp. 911-926
    • Kenward, M.G.1    Jones, B.2
  • 41
    • 78651290317 scopus 로고    scopus 로고
    • Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-alpha-mediated inflammation and insulin resistance in primary human adipocytes
    • COI: 1:CAS:528:DC%2BC3cXhsFGgtb%2FP
    • Chuang CC, Martinez K, Xie G, Kennedy A, Bumrungpert A, Overman A, Jia W, McIntosh MK (2010) Quercetin is equally or more effective than resveratrol in attenuating tumor necrosis factor-alpha-mediated inflammation and insulin resistance in primary human adipocytes. Am J Clin Nutr 92:1511–1521
    • (2010) Am J Clin Nutr , vol.92 , pp. 1511-1521
    • Chuang, C.C.1    Martinez, K.2    Xie, G.3    Kennedy, A.4    Bumrungpert, A.5    Overman, A.6    Jia, W.7    McIntosh, M.K.8
  • 42
    • 80052703398 scopus 로고    scopus 로고
    • Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage-conditioned media
    • COI: 1:CAS:528:DC%2BC3MXhtFyntbnF
    • Overman A, Chuang CC, McIntosh M (2011) Quercetin attenuates inflammation in human macrophages and adipocytes exposed to macrophage-conditioned media. Int J Obes (Lond) 35:1165–1172
    • (2011) Int J Obes (Lond) , vol.35 , pp. 1165-1172
    • Overman, A.1    Chuang, C.C.2    McIntosh, M.3
  • 43
    • 50649107938 scopus 로고    scopus 로고
    • Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese zucker rats
    • COI: 1:CAS:528:DC%2BD1cXhtVGgtL3F
    • Rivera L, Moron R, Sanchez M, Zarzuelo A, Galisteo M (2008) Quercetin ameliorates metabolic syndrome and improves the inflammatory status in obese zucker rats. Obesity (Silver Spring) 16:2081–2087
    • (2008) Obesity (Silver Spring) , vol.16 , pp. 2081-2087
    • Rivera, L.1    Moron, R.2    Sanchez, M.3    Zarzuelo, A.4    Galisteo, M.5
  • 44
    • 84864236699 scopus 로고    scopus 로고
    • Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice
    • COI: 1:CAS:528:DC%2BC38Xht1Git7nI
    • Jeong SM, Kang MJ, Choi HN, Kim JH, Kim JI (2012) Quercetin ameliorates hyperglycemia and dyslipidemia and improves antioxidant status in type 2 diabetic db/db mice. Nutr Res Pract 6:201–207
    • (2012) Nutr Res Pract , vol.6 , pp. 201-207
    • Jeong, S.M.1    Kang, M.J.2    Choi, H.N.3    Kim, J.H.4    Kim, J.I.5
  • 45
    • 79953317030 scopus 로고    scopus 로고
    • Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice
    • COI: 1:CAS:528:DC%2BC3MXktFemur8%3D
    • Kobori M, Masumoto S, Akimoto Y, Oike H (2011) Chronic dietary intake of quercetin alleviates hepatic fat accumulation associated with consumption of a Western-style diet in C57/BL6J mice. Mol Nutr Food Res 55:530–540
    • (2011) Mol Nutr Food Res , vol.55 , pp. 530-540
    • Kobori, M.1    Masumoto, S.2    Akimoto, Y.3    Oike, H.4
  • 47
    • 84871717518 scopus 로고    scopus 로고
    • Phytochemicals and their impact on adipose tissue inflammation and diabetes
    • COI: 1:CAS:528:DC%2BC38XhsVamu7bN
    • Leiherer A, Mundlein A, Drexel H (2013) Phytochemicals and their impact on adipose tissue inflammation and diabetes. Vascul Pharmacol 58:3–20
    • (2013) Vascul Pharmacol , vol.58 , pp. 3-20
    • Leiherer, A.1    Mundlein, A.2    Drexel, H.3
  • 48
    • 73749083955 scopus 로고    scopus 로고
    • Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study
    • COI: 1:CAS:528:DC%2BD1MXhsVSkurjP
    • Egert S, Bosy-Westphal A, Seiberl J, Kurbitz C, Settler U, Plachta-Danielzik S, Wagner AE, Frank J, Schrezenmeir J, Rimbach G, Wolffram S, Müller MJ (2009) Quercetin reduces systolic blood pressure and plasma oxidised low-density lipoprotein concentrations in overweight subjects with a high-cardiovascular disease risk phenotype: a double-blinded, placebo-controlled cross-over study. Br J Nutr 102:1065–1074
    • (2009) Br J Nutr , vol.102 , pp. 1065-1074
    • Egert, S.1    Bosy-Westphal, A.2    Seiberl, J.3    Kurbitz, C.4    Settler, U.5    Plachta-Danielzik, S.6    Wagner, A.E.7    Frank, J.8    Schrezenmeir, J.9    Rimbach, G.10    Wolffram, S.11    Müller, M.J.12
  • 49
    • 84883860974 scopus 로고    scopus 로고
    • Does quercetin improve cardiovascular risk factors and inflammatory biomarkers in women with type 2 diabetes: a double-blind randomized controlled clinical trial
    • Zahedi M, Ghiasvand R, Feizi A, Asgari G, Darvish L (2013) Does quercetin improve cardiovascular risk factors and inflammatory biomarkers in women with type 2 diabetes: a double-blind randomized controlled clinical trial. Int J Prev Med 4:777–785
    • (2013) Int J Prev Med , vol.4 , pp. 777-785
    • Zahedi, M.1    Ghiasvand, R.2    Feizi, A.3    Asgari, G.4    Darvish, L.5
  • 50
    • 33846867711 scopus 로고    scopus 로고
    • Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects
    • COI: 1:CAS:528:DC%2BD2sXhvFWhu74%3D
    • Zhao G, Etherton TD, Martin KR, Gillies PJ, West SG, Kris-Etherton PM (2007) Dietary alpha-linolenic acid inhibits proinflammatory cytokine production by peripheral blood mononuclear cells in hypercholesterolemic subjects. Am J Clin Nutr 85:385–391
    • (2007) Am J Clin Nutr , vol.85 , pp. 385-391
    • Zhao, G.1    Etherton, T.D.2    Martin, K.R.3    Gillies, P.J.4    West, S.G.5    Kris-Etherton, P.M.6
  • 51
    • 7944228499 scopus 로고    scopus 로고
    • Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women
    • COI: 1:CAS:528:DC%2BD2cXhtVSnsbrL
    • Zhao G, Etherton TD, Martin KR, West SG, Gillies PJ, Kris-Etherton PM (2004) Dietary alpha-linolenic acid reduces inflammatory and lipid cardiovascular risk factors in hypercholesterolemic men and women. J Nutr 134:2991–2997
    • (2004) J Nutr , vol.134 , pp. 2991-2997
    • Zhao, G.1    Etherton, T.D.2    Martin, K.R.3    West, S.G.4    Gillies, P.J.5    Kris-Etherton, P.M.6
  • 52
    • 84863238827 scopus 로고    scopus 로고
    • A low-glycemic load diet reduces serum C-reactive protein and modestly increases adiponectin in overweight and obese adults
    • COI: 1:CAS:528:DC%2BC38XhsFyjtLs%3D
    • Neuhouser ML, Schwarz Y, Wang C, Breymeyer K, Coronado G, Wang CY, Noar K, Song X, Lampe JW (2012) A low-glycemic load diet reduces serum C-reactive protein and modestly increases adiponectin in overweight and obese adults. J Nutr 142:369–374
    • (2012) J Nutr , vol.142 , pp. 369-374
    • Neuhouser, M.L.1    Schwarz, Y.2    Wang, C.3    Breymeyer, K.4    Coronado, G.5    Wang, C.Y.6    Noar, K.7    Song, X.8    Lampe, J.W.9
  • 53
    • 33947262450 scopus 로고    scopus 로고
    • Effect of a high-fiber diet vs a fiber-supplemented diet on C-reactive protein level
    • COI: 1:CAS:528:DC%2BD2sXktVCjurc%3D
    • King DE, Egan BM, Woolson RF, Mainous AG III, Al-Solaiman Y, Jesri A (2007) Effect of a high-fiber diet vs a fiber-supplemented diet on C-reactive protein level. Arch Intern Med 167:502–506
    • (2007) Arch Intern Med , vol.167 , pp. 502-506
    • King, D.E.1    Egan, B.M.2    Woolson, R.F.3    Mainous, A.G.4    Al-Solaiman, Y.5    Jesri, A.6
  • 54
    • 84880252433 scopus 로고    scopus 로고
    • Omega-3 polyunsaturated fatty acids increase plasma adiponectin to leptin ratio in stable coronary artery disease
    • COI: 1:CAS:528:DC%2BC3sXhtFajtLfF
    • Mostowik M, Gajos G, Zalewski J, Nessler J, Undas A (2013) Omega-3 polyunsaturated fatty acids increase plasma adiponectin to leptin ratio in stable coronary artery disease. Cardiovasc Drugs Ther 27:289–295
    • (2013) Cardiovasc Drugs Ther , vol.27 , pp. 289-295
    • Mostowik, M.1    Gajos, G.2    Zalewski, J.3    Nessler, J.4    Undas, A.5
  • 58
    • 74949133831 scopus 로고    scopus 로고
    • Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype
    • COI: 1:CAS:528:DC%2BC3cXltFSlsLY%3D
    • Egert S, Boesch-Saadatmandi C, Wolffram S, Rimbach G, Müller MJ (2010) Serum lipid and blood pressure responses to quercetin vary in overweight patients by apolipoprotein E genotype. J Nutr 140:278–284
    • (2010) J Nutr , vol.140 , pp. 278-284
    • Egert, S.1    Boesch-Saadatmandi, C.2    Wolffram, S.3    Rimbach, G.4    Müller, M.J.5
  • 59
    • 23244433350 scopus 로고    scopus 로고
    • Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress
    • COI: 1:CAS:528:DC%2BD2MXnvVSmurY%3D
    • Zern TL, Wood RJ, Greene C, West KL, Liu Y, Aggarwal D, Shachter NS, Fernandez ML (2005) Grape polyphenols exert a cardioprotective effect in pre- and postmenopausal women by lowering plasma lipids and reducing oxidative stress. J Nutr 135:1911–1917
    • (2005) J Nutr , vol.135 , pp. 1911-1917
    • Zern, T.L.1    Wood, R.J.2    Greene, C.3    West, K.L.4    Liu, Y.5    Aggarwal, D.6    Shachter, N.S.7    Fernandez, M.L.8
  • 60
    • 35848966547 scopus 로고    scopus 로고
    • Quercetin reduces blood pressure in hypertensive subjects
    • COI: 1:CAS:528:DC%2BD2sXht1ynsb3K
    • Edwards RL, Lyon T, Litwin SE, Rabovsky A, Symons JD, Jalili T (2007) Quercetin reduces blood pressure in hypertensive subjects. J Nutr 137:2405–2411
    • (2007) J Nutr , vol.137 , pp. 2405-2411
    • Edwards, R.L.1    Lyon, T.2    Litwin, S.E.3    Rabovsky, A.4    Symons, J.D.5    Jalili, T.6
  • 61
    • 79955583955 scopus 로고    scopus 로고
    • Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers
    • COI: 1:CAS:528:DC%2BC3MXkt1Sju78%3D
    • Lee KH, Park E, Lee HJ, Kim MO, Cha YJ, Kim JM, Lee H, Shin MJ (2011) Effects of daily quercetin-rich supplementation on cardiometabolic risks in male smokers. Nutr Res Pract 5:28–33
    • (2011) Nutr Res Pract , vol.5 , pp. 28-33
    • Lee, K.H.1    Park, E.2    Lee, H.J.3    Kim, M.O.4    Cha, Y.J.5    Kim, J.M.6    Lee, H.7    Shin, M.J.8
  • 62
    • 34548812546 scopus 로고    scopus 로고
    • A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties
    • COI: 1:CAS:528:DC%2BD2sXhtFWit7jN
    • Harwood M, Danielewska-Nikiel B, Borzelleca JF, Flamm GW, Williams GM, Lines TC (2007) A critical review of the data related to the safety of quercetin and lack of evidence of in vivo toxicity, including lack of genotoxic/carcinogenic properties. Food Chem Toxicol 45:2179–2205
    • (2007) Food Chem Toxicol , vol.45 , pp. 2179-2205
    • Harwood, M.1    Danielewska-Nikiel, B.2    Borzelleca, J.F.3    Flamm, G.W.4    Williams, G.M.5    Lines, T.C.6
  • 64
    • 33747061905 scopus 로고    scopus 로고
    • Comparison of serum high-molecular weight (HMW) adiponectin with total adiponectin concentrations in type 2 diabetic patients with coronary artery disease using a novel enzyme-linked immunosorbent assay to detect HMW adiponectin
    • COI: 1:CAS:528:DC%2BD28XmvVCht78%3D
    • Aso Y, Yamamoto R, Wakabayashi S, Uchida T, Takayanagi K, Takebayashi K, Okuno T, Inoue T, Node K, Tobe T, Inukai T, Nakano Y (2006) Comparison of serum high-molecular weight (HMW) adiponectin with total adiponectin concentrations in type 2 diabetic patients with coronary artery disease using a novel enzyme-linked immunosorbent assay to detect HMW adiponectin. Diabetes 55:1954–1960
    • (2006) Diabetes , vol.55 , pp. 1954-1960
    • Aso, Y.1    Yamamoto, R.2    Wakabayashi, S.3    Uchida, T.4    Takayanagi, K.5    Takebayashi, K.6    Okuno, T.7    Inoue, T.8    Node, K.9    Tobe, T.10    Inukai, T.11    Nakano, Y.12


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