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Volumn 41, Issue 12, 2016, Pages 2932-2940

The mGluR2 positive allosteric modulator, AZD8529, and cue-induced relapse to alcohol seeking in rats

Author keywords

[No Author keywords available]

Indexed keywords

7 METHYL 5 (3 PIPERAZIN 1 YLMETHYL[1,2,4]OXADIAZOL 5 YL) 2 (4 TRIFLUOROMETHOXYBENZYL) 2,3 DIHYDROISOINDOL 1 ONE; AGENTS INTERACTING WITH TRANSMITTER, HORMONE OR DRUG RECEPTORS; METABOTROPIC RECEPTOR 2; SACCHARIN; UNCLASSIFIED DRUG; ALCOHOL; AZD8529; INDOLE DERIVATIVE; METABOTROPIC RECEPTOR; OXADIAZOLE DERIVATIVE;

EID: 84978743838     PISSN: 0893133X     EISSN: 1740634X     Source Type: Journal    
DOI: 10.1038/npp.2016.107     Document Type: Article
Times cited : (33)

References (41)
  • 1
    • 84991383044 scopus 로고    scopus 로고
    • A method for evaluating the reinforcing properties of ethanol in rats without water deprivation, saccharin fading or extended access training
    • in press
    • Augier E, Dulman RS, Singley E, Heilig M. (2016). A method for evaluating the reinforcing properties of ethanol in rats without water deprivation, saccharin fading or extended access training. J Vis Exp (in press
    • (2016) J Vis Exp
    • Augier, E.1    Dulman, R.S.2    Singley, E.3    Heilig, M.4
  • 2
    • 84939881753 scopus 로고    scopus 로고
    • Wistar rats acquire and maintain self-Administration of 20% ethanol without water deprivation, saccharin/sucrose fading, or extended access training
    • Augier E, Flanigan M, Dulman RS, Pincus A, Schank JR, Rice KC., et al. (2014). Wistar rats acquire and maintain self-Administration of 20% ethanol without water deprivation, saccharin/sucrose fading, or extended access training. Psychopharmacology (Berl) 231: 4561-4568
    • (2014) Psychopharmacology (Berl) , vol.231 , pp. 4561-4568
    • Augier, E.1    Flanigan, M.2    Dulman, R.S.3    Pincus, A.4    Schank, J.R.5    Rice, K.C.6
  • 3
    • 28844433298 scopus 로고    scopus 로고
    • Suppression of alcohol selfadministration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3, 4-DCPG
    • Backstrom P, Hyytia P. (2005). Suppression of alcohol selfadministration and cue-induced reinstatement of alcohol seeking by the mGlu2/3 receptor agonist LY379268 and the mGlu8 receptor agonist (S)-3, 4-DCPG. Eur J Pharmacol 528: 110-118
    • (2005) Eur J Pharmacol , vol.528 , pp. 110-118
    • Backstrom, P.1    Hyytia, P.2
  • 4
    • 2442672865 scopus 로고    scopus 로고
    • Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement vs primary reinforcement: Comparison between cocaine and a potent conventional reinforcer
    • Baptista MA, Martin-Fardon R, Weiss F. (2004). Preferential effects of the metabotropic glutamate 2/3 receptor agonist LY379268 on conditioned reinstatement vs primary reinforcement: comparison between cocaine and a potent conventional reinforcer. J Neurosci 24: 4723-4727
    • (2004) J Neurosci , vol.24 , pp. 4723-4727
    • Baptista, M.A.1    Martin-Fardon, R.2    Weiss, F.3
  • 5
    • 21344434071 scopus 로고    scopus 로고
    • The novel mGluR2/3 agonist LY379268 attenuates cue-induced reinstatement of heroin seeking
    • Bossert JM, Busch RF, Gray SM. (2005). The novel mGluR2/3 agonist LY379268 attenuates cue-induced reinstatement of heroin seeking. Neuroreport 16: 1013-1016
    • (2005) Neuroreport , vol.16 , pp. 1013-1016
    • Bossert, J.M.1    Busch, R.F.2    Gray, S.M.3
  • 6
    • 9344230367 scopus 로고    scopus 로고
    • A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking
    • Bossert JM, Liu SY, Lu L, Shaham Y. (2004). A role of ventral tegmental area glutamate in contextual cue-induced relapse to heroin seeking. J Neurosci 24: 10726-10730
    • (2004) J Neurosci , vol.24 , pp. 10726-10730
    • Bossert, J.M.1    Liu, S.Y.2    Lu, L.3    Shaham, Y.4
  • 7
    • 84941100399 scopus 로고    scopus 로고
    • Effect of the novel positive allosteric modulator of metabotropic glutamate receptor 2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary abstinence in a rat model
    • Caprioli D, Venniro M, Zeric T, Li X, Adhikary S, Madangopal R., et al. (2015). Effect of the novel positive allosteric modulator of metabotropic glutamate receptor 2 AZD8529 on incubation of methamphetamine craving after prolonged voluntary abstinence in a rat model. Biol Psychiatry 78: 463-473
    • (2015) Biol Psychiatry , vol.78 , pp. 463-473
    • Caprioli, D.1    Venniro, M.2    Zeric, T.3    Li, X.4    Adhikary, S.5    Madangopal, R.6
  • 8
    • 58149119377 scopus 로고    scopus 로고
    • Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia
    • Conn PJ, Lindsley CW, Jones CK. (2009). Activation of metabotropic glutamate receptors as a novel approach for the treatment of schizophrenia. Trends Pharmacol Sci 30: 25-31
    • (2009) Trends Pharmacol Sci , vol.30 , pp. 25-31
    • Conn, P.J.1    Lindsley, C.W.2    Jones, C.K.3
  • 9
    • 0030995878 scopus 로고    scopus 로고
    • Pharmacology and functions of metabotropic glutamate receptors
    • Conn PJ, Pin JP. (1997). Pharmacology and functions of metabotropic glutamate receptors. Annu Rev Pharmacol Toxicol 37: 205-237
    • (1997) Annu Rev Pharmacol Toxicol , vol.37 , pp. 205-237
    • Conn, P.J.1    Pin, J.P.2
  • 10
    • 84941077875 scopus 로고    scopus 로고
    • AZD8529-An mGluR2 positive allosteric modulator for the treatment of schizophrenia
    • Cross AJ. (2013). AZD8529-An mGluR2 positive allosteric modulator for the treatment of schizophrenia. Neuropsychopharmacology 38: S25
    • (2013) Neuropsychopharmacology , vol.38 , pp. S25
    • Cross, A.J.1
  • 11
    • 0033953660 scopus 로고    scopus 로고
    • Taurine blocks the glutamate increase in the nucleus accumbens microdialysate of ethanoldependent rats
    • Dahchour A, De Witte P. (2000). Taurine blocks the glutamate increase in the nucleus accumbens microdialysate of ethanoldependent rats. Pharmacol Biochem Behav 65: 345-350
    • (2000) Pharmacol Biochem Behav , vol.65 , pp. 345-350
    • Dahchour, A.1    De Witte, P.2
  • 12
    • 0037449462 scopus 로고    scopus 로고
    • Excitatory and inhibitory amino acid changes during repeated episodes of ethanol withdrawal: An in vivo microdialysis study
    • Dahchour A, De Witte P. (2003). Excitatory and inhibitory amino acid changes during repeated episodes of ethanol withdrawal: an in vivo microdialysis study. Eur J Pharmacol 459: 171-178
    • (2003) Eur J Pharmacol , vol.459 , pp. 171-178
    • Dahchour, A.1    De Witte, P.2
  • 13
    • 36849072543 scopus 로고    scopus 로고
    • Glutamatergic substrates of drug addiction and alcoholism
    • Gass JT, Olive MF. (2008). Glutamatergic substrates of drug addiction and alcoholism. Biochem Pharmacol 75: 218-265
    • (2008) Biochem Pharmacol , vol.75 , pp. 218-265
    • Gass, J.T.1    Olive, M.F.2
  • 14
    • 0034769568 scopus 로고    scopus 로고
    • Effects of naltrexone on the intake of ethanol and flavored solutions in rats
    • Goodwin FL, Campisi M, Babinska I, Amit Z. (2001). Effects of naltrexone on the intake of ethanol and flavored solutions in rats. Alcohol 25: 9-19
    • (2001) Alcohol , vol.25 , pp. 9-19
    • Goodwin, F.L.1    Campisi, M.2    Babinska, I.3    Amit, Z.4
  • 15
    • 33746325472 scopus 로고    scopus 로고
    • Pharmacological treatment of alcohol dependence: Target symptoms and target mechanisms
    • Heilig M, Egli M. (2006). Pharmacological treatment of alcohol dependence: target symptoms and target mechanisms. Pharmacol Ther 111: 855-876
    • (2006) Pharmacol Ther , vol.111 , pp. 855-876
    • Heilig, M.1    Egli, M.2
  • 16
    • 84861096333 scopus 로고    scopus 로고
    • Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats
    • Hermann D, Weber-FahrW, Sartorius A, Hoerst M, Frischknecht U, Tunc-Skarka N., et al. (2012). Translational magnetic resonance spectroscopy reveals excessive central glutamate levels during alcohol withdrawal in humans and rats. Biol Psychiatry 71: 1015-1021
    • (2012) Biol Psychiatry , vol.71 , pp. 1015-1021
    • Hermann, D.1    Weber-Fahr, W.2    Sartorius, A.3    Hoerst, M.4    Frischknecht, U.5    Tunc-Skarka, N.6
  • 17
    • 0001099655 scopus 로고
    • Progressive ratio as a measure of reward strength
    • Hodos W. (1961). Progressive ratio as a measure of reward strength. Science 134: 943-944
    • (1961) Science , vol.134 , pp. 943-944
    • Hodos, W.1
  • 18
    • 77955717226 scopus 로고    scopus 로고
    • The mGluR2 positive allosteric modulator BINA decreases cocaine self-Administration and cue-induced cocaineseeking and counteracts cocaine-induced enhancement of brain reward function in rats
    • Jin X, Semenova S, Yang L, Ardecky R, Sheffler DJ, Dahl R., et al. (2010). The mGluR2 positive allosteric modulator BINA decreases cocaine self-Administration and cue-induced cocaineseeking and counteracts cocaine-induced enhancement of brain reward function in rats. Neuropsychopharmacology 35: 2021-2036
    • (2010) Neuropsychopharmacology , vol.35 , pp. 2021-2036
    • Jin, X.1    Semenova, S.2    Yang, L.3    Ardecky, R.4    Sheffler, D.J.5    Dahl, R.6
  • 19
    • 84941026458 scopus 로고    scopus 로고
    • The novel metabotropic glutamate receptor 2 positive allosteric modulator, ZD8529, decreases nicotine selfadministration and relapse in squirrel monkeys
    • Justinova Z, Panlilio LV, Secci ME, Redhi GH, Schindler CW, Cross AJ et al 2015). The novel metabotropic glutamate receptor 2 positive allosteric modulator, ZD8529, decreases nicotine selfadministration and relapse in squirrel monkeys. Biol Psychiatry 78: 452-462
    • (2015) Biol Psychiatry , vol.78 , pp. 452-462
    • Justinova, Z.1    Panlilio, L.V.2    Secci, M.E.3    Redhi, G.H.4    Schindler, C.W.5    Cross, A.J.6
  • 20
    • 67651083577 scopus 로고    scopus 로고
    • The glutamate homeostasis hypothesis of addiction
    • Kalivas PW. (2009). The glutamate homeostasis hypothesis of addiction. Nat Rev Neurosci 10: 561-572
    • (2009) Nat Rev Neurosci , vol.10 , pp. 561-572
    • Kalivas, P.W.1
  • 21
    • 2142757234 scopus 로고    scopus 로고
    • The ups and downs of addiction: Role of metabotropic glutamate receptors
    • Kenny PJ, Markou A. (2004). The ups and downs of addiction: role of metabotropic glutamate receptors. Trends Pharmacol Sci 25: 265-272
    • (2004) Trends Pharmacol Sci , vol.25 , pp. 265-272
    • Kenny, P.J.1    Markou, A.2
  • 22
    • 84872152328 scopus 로고    scopus 로고
    • Attenuation of methamphetamine seeking by the mGluR2/3 agonist LY379268 in rats with histories of restricted and escalated self-Administration
    • Kufahl PR, Watterson LR, Nemirovsky NE, Hood LE, Villa A, Halstengard C., et al. (2013). Attenuation of methamphetamine seeking by the mGluR2/3 agonist LY379268 in rats with histories of restricted and escalated self-Administration. Neuropharmacology 66: 290-301
    • (2013) Neuropharmacology , vol.66 , pp. 290-301
    • Kufahl, P.R.1    Watterson, L.R.2    Nemirovsky, N.E.3    Hood, L.E.4    Villa, A.5    Halstengard, C.6
  • 23
    • 0027324698 scopus 로고
    • Selective breeding for alcohol preference and associated responses
    • Li TK, Lumeng L, Doolittle DP. (1993). Selective breeding for alcohol preference and associated responses. Behav Genet 23: 163-170
    • (1993) Behav Genet , vol.23 , pp. 163-170
    • Li, T.K.1    Lumeng, L.2    Doolittle, D.P.3
  • 25
    • 34548151226 scopus 로고    scopus 로고
    • Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence
    • Liechti ME, Lhuillier L, Kaupmann K, Markou A. (2007). Metabotropic glutamate 2/3 receptors in the ventral tegmental area and the nucleus accumbens shell are involved in behaviors relating to nicotine dependence. J Neurosci 27: 9077-9085
    • (2007) J Neurosci , vol.27 , pp. 9077-9085
    • Liechti, M.E.1    Lhuillier, L.2    Kaupmann, K.3    Markou, A.4
  • 26
    • 33847371594 scopus 로고    scopus 로고
    • Systemic and central amygdala injections of the mGluR(2/3) agonist LY379268 attenuate the expression of incubation of cocaine craving
    • Lu L, Uejima JL, Gray SM, Bossert JM, Shaham Y. (2007). Systemic and central amygdala injections of the mGluR(2/3) agonist LY379268 attenuate the expression of incubation of cocaine craving. Biol Psychiatry 61: 591-598
    • (2007) Biol Psychiatry , vol.61 , pp. 591-598
    • Lu, L.1    Uejima, J.L.2    Gray, S.M.3    Bossert, J.M.4    Shaham, Y.5
  • 27
    • 30844432624 scopus 로고    scopus 로고
    • Glutamate-based therapeutic approaches: Allosteric modulators of metabotropic glutamate receptors
    • Marino MJ, Conn PJ. (2006). Glutamate-based therapeutic approaches: allosteric modulators of metabotropic glutamate receptors. Curr Opin Pharmacol 6: 98-102
    • (2006) Curr Opin Pharmacol , vol.6 , pp. 98-102
    • Marino, M.J.1    Conn, P.J.2
  • 28
    • 0032466081 scopus 로고    scopus 로고
    • Animal models of alcoholism: Neurobiology of high alcohol-drinking behavior in rodents
    • McBride WJ, Li TK. (1998). Animal models of alcoholism: neurobiology of high alcohol-drinking behavior in rodents. Crit Rev Neurobiol 12: 339-369
    • (1998) Crit Rev Neurobiol , vol.12 , pp. 339-369
    • McBride, W.J.1    Li, T.K.2
  • 29
    • 84873691604 scopus 로고    scopus 로고
    • Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence
    • Meinhardt MW, Hansson AC, Perreau-Lenz S, Bauder-Wenz C, Stahlin O, Heilig M., et al. (2013). Rescue of infralimbic mGluR2 deficit restores control over drug-seeking behavior in alcohol dependence. J Neurosci 33: 2794-2806
    • (2013) J Neurosci , vol.33 , pp. 2794-2806
    • Meinhardt, M.W.1    Hansson, A.C.2    Perreau-Lenz, S.3    Bauder-Wenz, C.4    Stahlin, O.5    Heilig, M.6
  • 30
    • 0034065936 scopus 로고    scopus 로고
    • Glutamate as a neurotransmitter in the brain: Review of physiology and pathology
    • Meldrum BS. (2000). Glutamate as a neurotransmitter in the brain: review of physiology and pathology. J Nutr 130: 1007S-1015S.
    • (2000) J Nutr 130: 1007S-1015S.
    • Meldrum, B.S.1
  • 31
    • 0029187946 scopus 로고
    • The metabotropic glutamate receptors: Structure and functions
    • Pin JP, Duvoisin R. (1995). The metabotropic glutamate receptors: structure and functions. Neuropharmacology 34: 1-26
    • (1995) Neuropharmacology , vol.34 , pp. 1-26
    • Pin, J.P.1    Duvoisin, R.2
  • 32
    • 26444616159 scopus 로고    scopus 로고
    • Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators
    • Ritzen A, Mathiesen JM, Thomsen C. (2005). Molecular pharmacology and therapeutic prospects of metabotropic glutamate receptor allosteric modulators. Basic Clin Pharmacol Toxicol 97: 202-213
    • (2005) Basic Clin Pharmacol Toxicol , vol.97 , pp. 202-213
    • Ritzen, A.1    Mathiesen, J.M.2    Thomsen, C.3
  • 33
    • 33745341119 scopus 로고    scopus 로고
    • The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-Administration in alcohol-preferring (P) rats
    • Rodd ZA, McKinzie DL, Bell RL, McQueen VK, Murphy JM, Schoepp DD., et al. (2006). The metabotropic glutamate 2/3 receptor agonist LY404039 reduces alcohol-seeking but not alcohol self-Administration in alcohol-preferring (P) rats. Behav Brain Res 171: 207-215
    • (2006) Behav Brain Res , vol.171 , pp. 207-215
    • Rodd, Z.A.1    McKinzie, D.L.2    Bell, R.L.3    McQueen, V.K.4    Murphy, J.M.5    Schoepp, D.D.6
  • 34
    • 0029119866 scopus 로고
    • Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum
    • Rossetti ZL, Carboni S. (1995). Ethanol withdrawal is associated with increased extracellular glutamate in the rat striatum. Eur J Pharmacol 283: 177-183
    • (1995) Eur J Pharmacol , vol.283 , pp. 177-183
    • Rossetti, Z.L.1    Carboni, S.2
  • 35
    • 0141569348 scopus 로고    scopus 로고
    • Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2
    • Schaffhauser H, Rowe BA, Morales S, Chavez-Noriega LE, Yin R, Jachec C., et al. (2003). Pharmacological characterization and identification of amino acids involved in the positive modulation of metabotropic glutamate receptor subtype 2. Mol Pharmacol 64: 798-810
    • (2003) Mol Pharmacol , vol.64 , pp. 798-810
    • Schaffhauser, H.1    Rowe, B.A.2    Morales, S.3    Chavez-Noriega, L.E.4    Yin, R.5    Jachec, C.6
  • 36
    • 0032834028 scopus 로고    scopus 로고
    • Pharmacological agents acting at subtypes of metabotropic glutamate receptors
    • Schoepp DD, Jane DE, Monn JA. (1999). Pharmacological agents acting at subtypes of metabotropic glutamate receptors. Neuropharmacology 38: 1431-1476
    • (1999) Neuropharmacology , vol.38 , pp. 1431-1476
    • Schoepp, D.D.1    De, J.2    Monn, J.A.3
  • 37
    • 77950357306 scopus 로고    scopus 로고
    • Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence
    • Sidhpura N, Weiss F, Martin-Fardon R. (2010). Effects of the mGlu2/3 agonist LY379268 and the mGlu5 antagonist MTEP on ethanol seeking and reinforcement are differentially altered in rats with a history of ethanol dependence. Biol Psychiatry 67: 804-811
    • (2010) Biol Psychiatry , vol.67 , pp. 804-811
    • Sidhpura, N.1    Weiss, F.2    Martin-Fardon, R.3
  • 38
    • 0042868860 scopus 로고    scopus 로고
    • Insight into the function of Group i and Group II metabotropic glutamate (mGlu) receptors: Behavioural characterization and implications for the treatment of CNS disorders
    • Spooren W, Ballard T, Gasparini F, Amalric M, Mutel V, Schreiber R. (2003). Insight into the function of Group I and Group II metabotropic glutamate (mGlu) receptors: behavioural characterization and implications for the treatment of CNS disorders. Behav Pharmacol 14: 257-277
    • (2003) Behav Pharmacol , vol.14 , pp. 257-277
    • Spooren, W.1    Ballard, T.2    Gasparini, F.3    Amalric, M.4    Mutel, V.5    Schreiber, R.6
  • 39
    • 77957690685 scopus 로고    scopus 로고
    • Ffect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcoholdependent individuals: A randomized controlled experimental medicine study
    • Umhau JC, Momenan R, Schwandt ML, Singley E, Lifshitz M, Doty L et al 2010). ffect of acamprosate on magnetic resonance spectroscopy measures of central glutamate in detoxified alcoholdependent individuals: a randomized controlled experimental medicine study. Arch Gen Psychiatry 67: 1069-1077
    • (2010) Arch Gen Psychiatry , vol.67 , pp. 1069-1077
    • Umhau, J.C.1    Momenan, R.2    Schwandt, M.L.3    Singley, E.4    Lifshitz, M.5    Doty, L.6
  • 40
    • 33749166779 scopus 로고    scopus 로고
    • Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala
    • Zhao Y, Dayas CV, Aujla H, Baptista MA, Martin-Fardon R, Weiss F. (2006). Activation of group II metabotropic glutamate receptors attenuates both stress and cue-induced ethanol-seeking and modulates c-fos expression in the hippocampus and amygdala. J Neurosci 26: 9967-9974
    • (2006) J Neurosci , vol.26 , pp. 9967-9974
    • Zhao, Y.1    Dayas, C.V.2    Aujla, H.3    Baptista, M.A.4    Martin-Fardon, R.5    Weiss, F.6


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