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Volumn 5, Issue , 2016, Pages

The myofibroblast in wound healing and fibrosis: Answered and unanswered questions

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; FIBRONECTIN; MYOSIN HEAVY CHAIN; TRANSFORMING GROWTH FACTOR BETA1;

EID: 84978529213     PISSN: 20461402     EISSN: 1759796X     Source Type: Journal    
DOI: 10.12688/f1000research.8190.1     Document Type: Review
Times cited : (216)

References (74)
  • 1
    • 1842309579 scopus 로고
    • The story of wound healing and wound repair
    • Reference Source, Springfield,.
    • Whipple AO: The story of wound healing and wound repair.Springfield,1963. Reference Source
    • (1963)
    • Whipple, A.O.1
  • 2
    • 0015225464 scopus 로고
    • Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction
    • 5132594
    • Gabbiani G Ryan GB Majno G: Presence of modified fibroblasts in granulation tissue and their possible role in wound contraction. Experientia. 1971;27(5):549-50. 5132594 10.1007/BF02147594
    • (1971) Experientia , vol.27 , Issue.5 , pp. 549-550
    • Gabbiani, G.1    Ryan, G.B.2    Majno, G.3
  • 3
    • 84907982888 scopus 로고    scopus 로고
    • The prehistory of the cytoskeleton concept
    • 24864014
    • Zampieri F Coen M Gabbiani G: The prehistory of the cytoskeleton concept. Cytoskeleton (Hoboken). 2014;71(8):464-71. 24864014 10.1002/cm.21177
    • (2014) Cytoskeleton (Hoboken) , vol.71 , Issue.8 , pp. 464-471
    • Zampieri, F.1    Coen, M.2    Gabbiani, G.3
  • 4
    • 0015321264 scopus 로고
    • Granulation tissue as a contractile organ. A study of structure and function
    • 4336123, 2139162
    • Gabbiani G Hirschel BJ Ryan GB: Granulation tissue as a contractile organ. A study of structure and function. J Exp Med. 1972;135(4):719-34. 4336123 2139162
    • (1972) J Exp Med , vol.135 , Issue.4 , pp. 719-734
    • Gabbiani, G.1    Hirschel, B.J.2    Ryan, G.B.3
  • 5
    • 0017812674 scopus 로고
    • Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing
    • 564911, 2110008
    • Gabbiani G Chaponnier C Hüttner I: Cytoplasmic filaments and gap junctions in epithelial cells and myofibroblasts during wound healing. J Cell Biol. 1978;76(3):561-8. 564911 10.1083/jcb.76.3.561 2110008
    • (1978) J Cell Biol , vol.76 , Issue.3 , pp. 561-568
    • Gabbiani, G.1    Chaponnier, C.2    Hüttner, I.3
  • 6
    • 0022881517 scopus 로고
    • A monoclonal antibody against alpha-smooth muscle actin:a new probe for smooth muscle differentiation
    • 3539945, 2114627
    • Skalli O Ropraz P Trzeciak A: A monoclonal antibody against alpha-smooth muscle actin: a new probe for smooth muscle differentiation. J Cell Biol. 1986;103(6 Pt 2):2787-96. 3539945 10.1083/jcb.103.6.2787 2114627
    • (1986) J Cell Biol , vol.103 , Issue.6 , pp. 2787-2796
    • Skalli, O.1    Ropraz, P.2    Trzeciak, A.3
  • 7
    • 0036277026 scopus 로고    scopus 로고
    • Myofibroblasts and mechano-regulation of connective tissue remodelling
    • 11988769
    • Tomasek JJ Gabbiani G Hinz B: Myofibroblasts and mechano-regulation of connective tissue remodelling. Nat Rev Mol Cell Biol. 2002;3(5):349-63. 11988769 10.1038/nrm809
    • (2002) Nat Rev Mol Cell Biol , vol.3 , Issue.5 , pp. 349-363
    • Tomasek, J.J.1    Gabbiani, G.2    Hinz, B.3
  • 8
    • 0028851160 scopus 로고
    • Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar
    • 7856739, 1870783
    • Desmoulière A Redard M Darby I: Apoptosis mediates the decrease in cellularity during the transition between granulation tissue and scar. Am J Pathol. 1995;146(1):56-66. 7856739 1870783
    • (1995) Am J Pathol , vol.146 , Issue.1 , pp. 56-66
    • Desmoulière, A.1    Redard, M.2    Darby, I.3
  • 9
    • 84904960909 scopus 로고    scopus 로고
    • Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis:Opportunities for New Therapeutic Intervention
    • 24527336, 3656629
    • Van De Water L Varney S Tomasek JJ: Mechanoregulation of the Myofibroblast in Wound Contraction, Scarring, and Fibrosis: Opportunities for New Therapeutic Intervention. Adv Wound Care (New Rochelle). 2013;2(4):122-41. 24527336 10.1089/wound.2012.0393 3656629
    • (2013) Adv Wound Care (New Rochelle) , vol.2 , Issue.4 , pp. 122-141
    • Van De Water, L.1    Varney, S.2    Tomasek, J.J.3
  • 10
    • 84859073207 scopus 로고    scopus 로고
    • Recent developments in myofibroblast biology:paradigms for connective tissue remodeling
    • 22387320, 3640252
    • Hinz B Phan SH Thannickal VJ: Recent developments in myofibroblast biology: paradigms for connective tissue remodeling. Am J Pathol. 2012;180(4):1340-55. 22387320 10.1016/j.ajpath.2012.02.004 3640252
    • (2012) Am J Pathol , vol.180 , Issue.4 , pp. 1340-1355
    • Hinz, B.1    Phan, S.H.2    Thannickal, V.J.3
  • 11
    • 84882815783 scopus 로고    scopus 로고
    • Heterogeneity of Smooth Muscle
    • Muscle: Elsevier
    • Arnoldi R Chaponnier C Gabbiani G: Heterogeneity of Smooth Muscle.In: Muscle: Elsevier,2012;1183-1195. 10.1016/B978-0-12-381510-1.00088-0
    • (2012) , pp. 1183-1195
    • Arnoldi, R.1    Chaponnier, C.2    Gabbiani, G.3
  • 12
    • 84863702343 scopus 로고    scopus 로고
    • Mechanisms of fibrosis:therapeutic translation for fibrotic disease
    • 22772564, 3405917
    • Wynn TA Ramalingam TR: Mechanisms of fibrosis: therapeutic translation for fibrotic disease. Nat Med. 2012;18(7):1028-40. 22772564 10.1038/nm.2807 3405917
    • (2012) Nat Med , vol.18 , Issue.7 , pp. 1028-1040
    • Wynn, T.A.1    Ramalingam, T.R.2
  • 13
    • 0027715980 scopus 로고
    • Macrophages and fibroblasts express embryonic fibronectins during cutaneous wound healing
    • 8456940, 1886786
    • Brown LF Dubin D Lavigne L: Macrophages and fibroblasts express embryonic fibronectins during cutaneous wound healing. Am J Pathol. 1993;142(3):793-801. 8456940 1886786
    • (1993) Am J Pathol , vol.142 , Issue.3 , pp. 793-801
    • Brown, L.F.1    Dubin, D.2    Lavigne, L.3
  • 14
    • 9744274523 scopus 로고    scopus 로고
    • The spatial and temporal expression patterns of integrin alpha9beta1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing
    • 15610531, F1000 Recommendation
    • Singh P Reimer CL Peters JH: The spatial and temporal expression patterns of integrin alpha9beta1 and one of its ligands, the EIIIA segment of fibronectin, in cutaneous wound healing. J Invest Dermatol. 2004;123(6):1176-81. 15610531 10.1111/j.0022-202X.2004.23485.x F1000 Recommendation
    • (2004) J Invest Dermatol , vol.123 , Issue.6 , pp. 1176-1181
    • Singh, P.1    Reimer, C.L.2    Peters, J.H.3
  • 15
    • 0031828004 scopus 로고    scopus 로고
    • The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1
    • 9700173, 2148176
    • Serini G Bochaton-Piallat ML Ropraz P: The fibronectin domain ED-A is crucial for myofibroblastic phenotype induction by transforming growth factor-beta1. J Cell Biol. 1998;142(3):873-81. 9700173 10.1083/jcb.142.3.873 2148176
    • (1998) J Cell Biol , vol.142 , Issue.3 , pp. 873-881
    • Serini, G.1    Bochaton-Piallat, M.L.2    Ropraz, P.3
  • 16
    • 30944452186 scopus 로고    scopus 로고
    • Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers
    • 16401722, 2063555, F1000 Recommendation
    • Goffin JM Pittet P Csucs G: Focal adhesion size controls tension-dependent recruitment of alpha-smooth muscle actin to stress fibers. J Cell Biol. 2006;172(2):259-68. 16401722 10.1083/jcb.200506179 2063555 F1000 Recommendation
    • (2006) J Cell Biol , vol.172 , Issue.2 , pp. 259-268
    • Goffin, J.M.1    Pittet, P.2    Csucs, G.3
  • 17
    • 78049365986 scopus 로고    scopus 로고
    • Cell motility and mechanics in three-dimensional collagen matrices
    • 19575667
    • Grinnell F Petroll WM: Cell motility and mechanics in three-dimensional collagen matrices. Annu Rev Cell Dev Biol. 2010;26:335-61. 19575667 10.1146/annurev.cellbio.042308.113318
    • (2010) Annu Rev Cell Dev Biol , vol.26 , pp. 335-361
    • Grinnell, F.1    Petroll, W.M.2
  • 18
    • 0027212686 scopus 로고
    • Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts
    • 8314838, 2119614
    • Desmoulière A Geinoz A Gabbiani F: Transforming growth factor-beta 1 induces alpha-smooth muscle actin expression in granulation tissue myofibroblasts and in quiescent and growing cultured fibroblasts. J Cell Biol. 1993;122(1):103-11. 8314838 10.1083/jcb.122.1.103 2119614
    • (1993) J Cell Biol , vol.122 , Issue.1 , pp. 103-111
    • Desmoulière, A.1    Geinoz, A.2    Gabbiani, F.3
  • 19
    • 84901625332 scopus 로고    scopus 로고
    • Mechanotransduction and fibrosis
    • 24709567, 4425300
    • Duscher D Maan ZN Wong VW: Mechanotransduction and fibrosis. J Biomech. 2014;47(9):1997-2005. 24709567 10.1016/j.jbiomech.2014.03.031 4425300
    • (2014) J Biomech , vol.47 , Issue.9 , pp. 1997-2005
    • Duscher, D.1    Maan, Z.N.2    Wong, V.W.3
  • 20
    • 84943817650 scopus 로고    scopus 로고
    • The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship
    • 25960420
    • Hinz B: The extracellular matrix and transforming growth factor-β1: Tale of a strained relationship. Matrix Biol. 2015;47:54-65. 25960420 10.1016/j.matbio.2015.05.006
    • (2015) Matrix Biol , vol.47 , pp. 54-65
    • Hinz, B.1
  • 21
    • 84988884449 scopus 로고    scopus 로고
    • Stretch Induced Activation of TGF-β1 in Pulmonary Fibrosis
    • 26771871, F1000 Recommendation
    • Froese AR Shimbori C Bellaye PS: Stretch Induced Activation of TGF-β1 in Pulmonary Fibrosis. Am J Respir Crit Care Med. 2016. 26771871 10.1164/rccm.201508-1638OC F1000 Recommendation
    • (2016) Am J Respir Crit Care Med
    • Froese, A.R.1    Shimbori, C.2    Bellaye, P.S.3
  • 22
    • 84910601354 scopus 로고    scopus 로고
    • Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation
    • 25332161, 4210443, F1000 Recommendation
    • Klingberg F Chow ML Koehler A: Prestress in the extracellular matrix sensitizes latent TGF-β1 for activation. J Cell Biol. 2014;207(2):283-97. 25332161 10.1083/jcb.201402006 4210443 F1000 Recommendation
    • (2014) J Cell Biol , vol.207 , Issue.2 , pp. 283-297
    • Klingberg, F.1    Chow, M.L.2    Koehler, A.3
  • 23
    • 84871046283 scopus 로고    scopus 로고
    • The myofibroblast matrix:implications for tissue repair and fibrosis
    • 22996908, 4005341
    • Klingberg F Hinz B White ES: The myofibroblast matrix: implications for tissue repair and fibrosis. J Pathol. 2013;229(2):298-309. 22996908 10.1002/path.4104 4005341
    • (2013) J Pathol , vol.229 , Issue.2 , pp. 298-309
    • Klingberg, F.1    Hinz, B.2    White, E.S.3
  • 24
    • 0035159094 scopus 로고    scopus 로고
    • Alpha-smooth muscle actin expression upregulates fibroblast contractile activity
    • 11553712, 59708
    • Hinz B Celetta G Tomasek JJ: Alpha-smooth muscle actin expression upregulates fibroblast contractile activity. Mol Biol Cell. 2001;12(9):2730-41. 11553712 10.1091/mbc.12.9.2730 59708
    • (2001) Mol Biol Cell , vol.12 , Issue.9 , pp. 2730-2741
    • Hinz, B.1    Celetta, G.2    Tomasek, J.J.3
  • 25
    • 0034778401 scopus 로고    scopus 로고
    • Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors
    • 11591817
    • Dugina V Fontao L Chaponnier C: Focal adhesion features during myofibroblastic differentiation are controlled by intracellular and extracellular factors. J Cell Sci. 2001;114(Pt 18):3285-96. 11591817
    • (2001) J Cell Sci , vol.114 , pp. 3285-3296
    • Dugina, V.1    Fontao, L.2    Chaponnier, C.3
  • 26
    • 84961219361 scopus 로고    scopus 로고
    • Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation
    • 26759173, 4760373
    • Varney SD Betts CB Zheng R: Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation. J Cell Sci. 2016;129(4):774-87. 26759173 10.1242/jcs.170589 4760373
    • (2016) J Cell Sci , vol.129 , Issue.4 , pp. 774-787
    • Varney, S.D.1    Betts, C.B.2    Zheng, R.3
  • 27
    • 77954243065 scopus 로고    scopus 로고
    • The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing
    • 20526329, 2919364, F1000 Recommendation
    • Jun JI Lau LF: The matricellular protein CCN1 induces fibroblast senescence and restricts fibrosis in cutaneous wound healing. Nat Cell Biol. 2010;12(7):676-85. 20526329 10.1038/ncb2070 2919364 F1000 Recommendation
    • (2010) Nat Cell Biol , vol.12 , Issue.7 , pp. 676-685
    • Jun, J.I.1    Lau, L.F.2
  • 28
    • 84862195154 scopus 로고    scopus 로고
    • Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis
    • 22566629, 3386114, F1000 Recommendation
    • Kisseleva T Cong M Paik Y: Myofibroblasts revert to an inactive phenotype during regression of liver fibrosis. Proc Natl Acad Sci U S A. 2012;109(24):9448-53. 22566629 10.1073/pnas.1201840109 3386114 F1000 Recommendation
    • (2012) Proc Natl Acad Sci U S A , vol.109 , Issue.24 , pp. 9448-9453
    • Kisseleva, T.1    Cong, M.2    Paik, Y.3
  • 29
    • 0034141607 scopus 로고    scopus 로고
    • Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase
    • 10640419, F1000 Recommendation
    • Parizi M Howard EW Tomasek JJ: Regulation of LPA-promoted myofibroblast contraction: role of Rho, myosin light chain kinase, and myosin light chain phosphatase. Exp Cell Res. 2000;254(2):210-20. 10640419 10.1006/excr.1999.4754 F1000 Recommendation
    • (2000) Exp Cell Res , vol.254 , Issue.2 , pp. 210-220
    • Parizi, M.1    Howard, E.W.2    Tomasek, J.J.3
  • 30
    • 3242729348 scopus 로고    scopus 로고
    • Rho-mediated assembly of stress fibers is differentially regulated in corneal fibroblasts and myofibroblasts
    • 15265703, F1000 Recommendation
    • Anderson S DiCesare L Tan I: Rho-mediated assembly of stress fibers is differentially regulated in corneal fibroblasts and myofibroblasts. Exp Cell Res. 2004;298(2):574-83. 15265703 10.1016/j.yexcr.2004.05.005 F1000 Recommendation
    • (2004) Exp Cell Res , vol.298 , Issue.2 , pp. 574-583
    • Anderson, S.1    DiCesare, L.2    Tan, I.3
  • 31
    • 33745544013 scopus 로고    scopus 로고
    • Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity
    • 16808810
    • Tomasek JJ Vaughan MB Kropp BP: Contraction of myofibroblasts in granulation tissue is dependent on Rho/Rho kinase/myosin light chain phosphatase activity. Wound Repair Regen. 2006;14(3):313-20. 16808810 10.1111/j.1743-6109.2006.00126.x
    • (2006) Wound Repair Regen , vol.14 , Issue.3 , pp. 313-320
    • Tomasek, J.J.1    Vaughan, M.B.2    Kropp, B.P.3
  • 32
    • 80855143589 scopus 로고    scopus 로고
    • Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation
    • Jr, 21776010, 3199034, F1000 Recommendation
    • Crider BJ Risinger GM Jr Haaksma CJ: Myocardin-related transcription factors A and B are key regulators of TGF-β1-induced fibroblast to myofibroblast differentiation. J Invest Dermatol. 2011;131(12):2378-85. 21776010 10.1038/jid.2011.219 3199034 F1000 Recommendation
    • (2011) J Invest Dermatol , vol.131 , Issue.12 , pp. 2378-2385
    • Crider, B.J.1    Risinger, G.M.2    Haaksma, C.J.3
  • 33
    • 84896820736 scopus 로고    scopus 로고
    • TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms
    • 24424023, F1000 Recommendation
    • Scharenberg MA Pippenger BE Sack R: TGF-β-induced differentiation into myofibroblasts involves specific regulation of two MKL1 isoforms. J Cell Sci. 2014;127(Pt 5):1079-91. 24424023 10.1242/jcs.142075 F1000 Recommendation
    • (2014) J Cell Sci , vol.127 , pp. 1079-1091
    • Scharenberg, M.A.1    Pippenger, B.E.2    Sack, R.3
  • 34
    • 84874609382 scopus 로고    scopus 로고
    • Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis
    • 23434591, 3582144, F1000 Recommendation
    • Zhou Y Huang X Hecker L: Inhibition of mechanosensitive signaling in myofibroblasts ameliorates experimental pulmonary fibrosis. J Clin Invest. 2013;123(3):1096-108. 23434591 10.1172/JCI66700 3582144 F1000 Recommendation
    • (2013) J Clin Invest , vol.123 , Issue.3 , pp. 1096-1108
    • Zhou, Y.1    Huang, X.2    Hecker, L.3
  • 35
    • 77955173404 scopus 로고    scopus 로고
    • Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction
    • 20558820, 2921870, F1000 Recommendation
    • Small EM Thatcher JE Sutherland LB: Myocardin-related transcription factor-a controls myofibroblast activation and fibrosis in response to myocardial infarction. Circ Res. 2010;107(2):294-304. 20558820 10.1161/CIRCRESAHA.110.223172 2921870 F1000 Recommendation
    • (2010) Circ Res , vol.107 , Issue.2 , pp. 294-304
    • Small, E.M.1    Thatcher, J.E.2    Sutherland, L.B.3
  • 36
    • 83755162557 scopus 로고    scopus 로고
    • Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts
    • 22049076, 3243519, F1000 Recommendation
    • Luchsinger LL Patenaude CA Smith BD: Myocardin-related transcription factor-A complexes activate type I collagen expression in lung fibroblasts. J Biol Chem. 2011;286(51):44116-25. 22049076 10.1074/jbc.M111.276931 3243519 F1000 Recommendation
    • (2011) J Biol Chem , vol.286 , Issue.51 , pp. 44116-44125
    • Luchsinger, L.L.1    Patenaude, C.A.2    Smith, B.D.3
  • 37
    • 84901218345 scopus 로고    scopus 로고
    • Targeting the myofibroblast genetic switch:inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury
    • 24706986, 4019321, F1000 Recommendation
    • Haak AJ Tsou PS Amin MA: Targeting the myofibroblast genetic switch: inhibitors of myocardin-related transcription factor/serum response factor-regulated gene transcription prevent fibrosis in a murine model of skin injury. J Pharmacol Exp Ther. 2014;349(3):480-6. 24706986 10.1124/jpet.114.213520 4019321 F1000 Recommendation
    • (2014) J Pharmacol Exp Ther , vol.349 , Issue.3 , pp. 480-486
    • Haak, A.J.1    Tsou, P.S.2    Amin, M.A.3
  • 38
    • 84893643399 scopus 로고    scopus 로고
    • Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts
    • 24280883, F1000 Recommendation
    • Johnson LA Rodansky ES Haak AJ: Novel Rho/MRTF/SRF inhibitors block matrix-stiffness and TGF-β-induced fibrogenesis in human colonic myofibroblasts. Inflamm Bowel Dis. 2014;20(1):154-65. 24280883 10.1097/01.MIB.0000437615.98881.31 F1000 Recommendation
    • (2014) Inflamm Bowel Dis , vol.20 , Issue.1 , pp. 154-165
    • Johnson, L.A.1    Rodansky, E.S.2    Haak, A.J.3
  • 39
    • 84865411430 scopus 로고    scopus 로고
    • Transduction of mechanical and cytoskeletal cues by YAP and TAZ
    • 22895435
    • Halder G Dupont S Piccolo S: Transduction of mechanical and cytoskeletal cues by YAP and TAZ. Nat Rev Mol Cell Biol. 2012;13(9):591-600. 22895435 10.1038/nrm3416
    • (2012) Nat Rev Mol Cell Biol , vol.13 , Issue.9 , pp. 591-600
    • Halder, G.1    Dupont, S.2    Piccolo, S.3
  • 40
    • 84930925721 scopus 로고    scopus 로고
    • Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells
    • 26028530, 4471834
    • Talele NP Fradette J Davies JE: Expression of α-Smooth Muscle Actin Determines the Fate of Mesenchymal Stromal Cells. Stem Cell Reports. 2015;4(6):1016-30. 26028530 10.1016/j.stemcr.2015.05.004 4471834
    • (2015) Stem Cell Reports , vol.4 , Issue.6 , pp. 1016-1030
    • Talele, N.P.1    Fradette, J.2    Davies, J.E.3
  • 41
    • 84878615570 scopus 로고    scopus 로고
    • Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts
    • 23708000, 3836234, F1000 Recommendation
    • Calvo F Ege N Grande-Garcia A: Mechanotransduction and YAP-dependent matrix remodelling is required for the generation and maintenance of cancer-associated fibroblasts. Nat Cell Biol. 2013;15(6):637-46. 23708000 10.1038/ncb2756 3836234 F1000 Recommendation
    • (2013) Nat Cell Biol , vol.15 , Issue.6 , pp. 637-646
    • Calvo, F.1    Ege, N.2    Grande-Garcia, A.3
  • 42
    • 84922967715 scopus 로고    scopus 로고
    • Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis
    • 25502501, 4329470, F1000 Recommendation
    • Liu F Lagares D Choi KM: Mechanosignaling through YAP and TAZ drives fibroblast activation and fibrosis. Am J Physiol Lung Cell Mol Physiol. 2015;308(4):L344-57. 25502501 10.1152/ajplung.00300.2014 4329470 F1000 Recommendation
    • (2015) Am J Physiol Lung Cell Mol Physiol , vol.308 , Issue.4 , pp. L344-L357
    • Liu, F.1    Lagares, D.2    Choi, K.M.3
  • 43
    • 84887087639 scopus 로고    scopus 로고
    • Differential topical susceptibility to TGFβin intact and injured regions of the epithelium:key role in myofibroblast transition
    • 24006486, 3814143
    • Speight P Nakano H Kelley TJ: Differential topical susceptibility to TGFβ in intact and injured regions of the epithelium: key role in myofibroblast transition. Mol Biol Cell. 2013;24(21):3326-36. 24006486 10.1091/mbc.E13-04-0220 3814143
    • (2013) Mol Biol Cell , vol.24 , Issue.21 , pp. 3326-3336
    • Speight, P.1    Nakano, H.2    Kelley, T.J.3
  • 44
    • 84947765582 scopus 로고    scopus 로고
    • YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts
    • 26458763
    • Piersma B de Rond S Werker PM: YAP1 Is a Driver of Myofibroblast Differentiation in Normal and Diseased Fibroblasts. Am J Pathol. 2015;185(12):3326-37. 26458763 10.1016/j.ajpath.2015.08.011
    • (2015) Am J Pathol , vol.185 , Issue.12 , pp. 3326-3337
    • Piersma, B.1    de Rond, S.2    Werker, P.M.3
  • 45
    • 84890350271 scopus 로고    scopus 로고
    • Distinct fibroblast lineages determine dermal architecture in skin development and repair
    • 24336287, 3868929, F1000 Recommendation
    • Driskell RR Lichtenberger BM Hoste E: Distinct fibroblast lineages determine dermal architecture in skin development and repair. Nature. 2013;504(7479):277-81. 24336287 10.1038/nature12783 3868929 F1000 Recommendation
    • (2013) Nature , vol.504 , Issue.7479 , pp. 277-281
    • Driskell, R.R.1    Lichtenberger, B.M.2    Hoste, E.3
  • 46
    • 84927739773 scopus 로고    scopus 로고
    • Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential
    • aaa2151, 25883361, F1000 Recommendation
    • Rinkevich Y Walmsley GG Hu MS: Skin fibrosis. Identification and isolation of a dermal lineage with intrinsic fibrogenic potential. Science. 2015;348(6232):aaa2151. 25883361 10.1126/science.aaa2151 F1000 Recommendation
    • (2015) Science , vol.348 , Issue.6232
    • Rinkevich, Y.1    Walmsley, G.G.2    Hu, M.S.3
  • 47
    • 84903762014 scopus 로고    scopus 로고
    • Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis
    • 24937432, 4071409, F1000 Recommendation
    • Moore-Morris T Guimarães-Camboa N Banerjee I: Resident fibroblast lineages mediate pressure overload-induced cardiac fibrosis. J Clin Invest. 2014;124(7):2921-34. 24937432 10.1172/JCI74783 4071409 F1000 Recommendation
    • (2014) J Clin Invest , vol.124 , Issue.7 , pp. 2921-2934
    • Moore-Morris, T.1    Guimarães-Camboa, N.2    Banerjee, I.3
  • 48
    • 84925813798 scopus 로고    scopus 로고
    • Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors
    • 25504959, 4472310, F1000 Recommendation
    • Marangoni RG Korman BD Wei J: Myofibroblasts in murine cutaneous fibrosis originate from adiponectin-positive intradermal progenitors. Arthritis Rheumatol. 2015;67(4):1062-73. 25504959 10.1002/art.38990 4472310 F1000 Recommendation
    • (2015) Arthritis Rheumatol , vol.67 , Issue.4 , pp. 1062-1073
    • Marangoni, R.G.1    Korman, B.D.2    Wei, J.3
  • 49
    • 33644868596 scopus 로고    scopus 로고
    • Phenotypic modulation of intima and media smooth muscle cells in fatal cases of coronary artery lesion
    • 16339500
    • Hao H Gabbiani G Camenzind E: Phenotypic modulation of intima and media smooth muscle cells in fatal cases of coronary artery lesion. Arterioscler Thromb Vasc Biol. 2006;26(2):326-32. 16339500 10.1161/01.ATV.0000199393.74656.4c
    • (2006) Arterioscler Thromb Vasc Biol , vol.26 , Issue.2 , pp. 326-332
    • Hao, H.1    Gabbiani, G.2    Camenzind, E.3
  • 50
    • 84937828512 scopus 로고    scopus 로고
    • Myofibroblasts
    • 26192991
    • Hinz B: Myofibroblasts. Exp Eye Res. 2016;142:56-70. 26192991 10.1016/j.exer.2015.07.009
    • (2016) Exp Eye Res , vol.142 , pp. 56-70
    • Hinz, B.1
  • 51
    • 84961668514 scopus 로고    scopus 로고
    • The corneal fibrosis response to epithelial-stromal injury
    • 26675407, 4683352, F1000 Recommendation
    • Torricelli AA Santhanam A Wu J: The corneal fibrosis response to epithelial-stromal injury. Exp Eye Res. 2016;142:110-8. 26675407 10.1016/j.exer.2014.09.012 4683352 F1000 Recommendation
    • (2016) Exp Eye Res , vol.142 , pp. 110-118
    • Torricelli, A.A.1    Santhanam, A.2    Wu, J.3
  • 52
    • 77955472579 scopus 로고    scopus 로고
    • Evolving challenges in hepatic fibrosis
    • 20585339, F1000 Recommendation
    • Friedman SL: Evolving challenges in hepatic fibrosis. Nat Rev Gastroenterol Hepatol. 2010;7(8):425-36. 20585339 10.1038/nrgastro.2010.97 F1000 Recommendation
    • (2010) Nat Rev Gastroenterol Hepatol , vol.7 , Issue.8 , pp. 425-436
    • Friedman, S.L.1
  • 53
    • 84920730709 scopus 로고    scopus 로고
    • + progenitors are key contributors to injury-induced organ fibrosis
    • 25465115, 4289444, F1000 Recommendation
    • Kramann R Schneider RK DiRocco DP: Perivascular Gli1 + progenitors are key contributors to injury-induced organ fibrosis. Cell Stem Cell. 2015;16(1):51-66. 25465115 10.1016/j.stem.2014.11.004 4289444 F1000 Recommendation
    • (2015) Cell Stem Cell , vol.16 , Issue.1 , pp. 51-66
    • Kramann, R.1    Schneider, R.K.2    DiRocco, D.P.3
  • 54
    • 84885605055 scopus 로고    scopus 로고
    • Origins of fibrosis:pericytes take centre stage
    • 24049641, 3768328, F1000 Recommendation
    • Greenhalgh SN Iredale JP Henderson NC: Origins of fibrosis: pericytes take centre stage. F1000Prime Rep. 2013;5:37. 24049641 10.12703/P5-37 3768328 F1000 Recommendation
    • (2013) F1000Prime Rep , vol.5 , pp. 37
    • Greenhalgh, S.N.1    Iredale, J.P.2    Henderson, N.C.3
  • 55
    • 84902179695 scopus 로고    scopus 로고
    • Cellular and molecular mechanisms in kidney fibrosis
    • 24892703, 4038570, F1000 Recommendation
    • Duffield JS: Cellular and molecular mechanisms in kidney fibrosis. J Clin Invest. 2014;124(6):2299-306. 24892703 10.1172/JCI72267 4038570 F1000 Recommendation
    • (2014) J Clin Invest , vol.124 , Issue.6 , pp. 2299-2306
    • Duffield, J.S.1
  • 56
    • 1642379154 scopus 로고    scopus 로고
    • The role of epithelial-to-mesenchymal transition in renal fibrosis
    • 14752606
    • Zeisberg M Kalluri R: The role of epithelial-to-mesenchymal transition in renal fibrosis. J Mol Med (Berl). 2004;82(3):175-81. 14752606 10.1007/s00109-003-0517-9
    • (2004) J Mol Med (Berl) , vol.82 , Issue.3 , pp. 175-181
    • Zeisberg, M.1    Kalluri, R.2
  • 57
    • 33748375828 scopus 로고    scopus 로고
    • Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix
    • 16924102, 1551904, F1000 Recommendation
    • Kim KK Kugler MC Wolters PJ: Alveolar epithelial cell mesenchymal transition develops in vivo during pulmonary fibrosis and is regulated by the extracellular matrix. Proc Natl Acad Sci U S A. 2006;103(35):13180-5. 16924102 10.1073/pnas.0605669103 1551904 F1000 Recommendation
    • (2006) Proc Natl Acad Sci U S A , vol.103 , Issue.35 , pp. 13180-13185
    • Kim, K.K.1    Kugler, M.C.2    Wolters, P.J.3
  • 58
    • 84937890270 scopus 로고    scopus 로고
    • Inhibition of matrix metalloproteinase activity reverses corneal endothelial-mesenchymal transition
    • 26216284
    • Ho WT Chang JS Su CC: Inhibition of matrix metalloproteinase activity reverses corneal endothelial-mesenchymal transition. Am J Pathol. 2015;185(8):2158-67. 26216284 10.1016/j.ajpath.2015.04.005
    • (2015) Am J Pathol , vol.185 , Issue.8 , pp. 2158-2167
    • Ho, W.T.1    Chang, J.S.2    Su, C.C.3
  • 59
    • 84871945372 scopus 로고    scopus 로고
    • The role of circulating fibrocytes in inflammation and autoimmunity
    • 22993208, F1000 Recommendation
    • Galligan CL Fish EN: The role of circulating fibrocytes in inflammation and autoimmunity. J Leukoc Biol. 2013;93(1):45-50. 22993208 10.1189/jlb.0712365 F1000 Recommendation
    • (2013) J Leukoc Biol , vol.93 , Issue.1 , pp. 45-50
    • Galligan, C.L.1    Fish, E.N.2
  • 60
    • 79957624520 scopus 로고    scopus 로고
    • Fibrocytes: emerging effector cells in chronic inflammation
    • 21597472, 3599774, F1000 Recommendation
    • Reilkoff RA Bucala R Herzog EL: Fibrocytes: emerging effector cells in chronic inflammation. Nat Rev Immunol. 2011;11(6):427-35. 21597472 10.1038/nri2990 3599774 F1000 Recommendation
    • (2011) Nat Rev Immunol , vol.11 , Issue.6 , pp. 427-435
    • Reilkoff, R.A.1    Bucala, R.2    Herzog, E.L.3
  • 61
    • 77953361398 scopus 로고    scopus 로고
    • Corneal myofibroblast generation from bone marrow-derived cells
    • 20417632, 2887716, F1000 Recommendation
    • Barbosa FL Chaurasia SS Cutler A: Corneal myofibroblast generation from bone marrow-derived cells. Exp Eye Res. 2010;91(1):92-6. 20417632 10.1016/j.exer.2010.04.007 2887716 F1000 Recommendation
    • (2010) Exp Eye Res , vol.91 , Issue.1 , pp. 92-96
    • Barbosa, F.L.1    Chaurasia, S.S.2    Cutler, A.3
  • 62
    • 9244236047 scopus 로고    scopus 로고
    • Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts
    • 15574751, F1000 Recommendation
    • Direkze NC Hodivala-Dilke K Jeffery R: Bone marrow contribution to tumor-associated myofibroblasts and fibroblasts. Cancer Res. 2004;64(23):8492-5. 15574751 10.1158/0008-5472.CAN-04-1708 F1000 Recommendation
    • (2004) Cancer Res , vol.64 , Issue.23 , pp. 8492-8495
    • Direkze, N.C.1    Hodivala-Dilke, K.2    Jeffery, R.3
  • 63
    • 84897052480 scopus 로고    scopus 로고
    • Cell therapy for cardiac repair--lessons from clinical trials
    • 24594893, F1000 Recommendation
    • Behfar A Crespo-Diaz R Terzic A: Cell therapy for cardiac repair--lessons from clinical trials. Nat Rev Cardiol. 2014;11(4):232-46. 24594893 10.1038/nrcardio.2014.9 F1000 Recommendation
    • (2014) Nat Rev Cardiol , vol.11 , Issue.4 , pp. 232-246
    • Behfar, A.1    Crespo-Diaz, R.2    Terzic, A.3
  • 64
    • 84872088799 scopus 로고    scopus 로고
    • The meaning, the sense and the significance:translating the science of mesenchymal stem cells into medicine
    • 23296015, 3998103, F1000 Recommendation
    • Bianco P Cao X Frenette PS: The meaning, the sense and the significance: translating the science of mesenchymal stem cells into medicine. Nat Med. 2013;19(1):35-42. 23296015 10.1038/nm.3028 3998103 F1000 Recommendation
    • (2013) Nat Med , vol.19 , Issue.1 , pp. 35-42
    • Bianco, P.1    Cao, X.2    Frenette, P.S.3
  • 66
    • 84872338388 scopus 로고    scopus 로고
    • Therapy for fibrotic diseases:nearing the starting line
    • 167sr1, 23303606
    • Friedman SL Sheppard D Duffield JS: Therapy for fibrotic diseases: nearing the starting line. Sci Transl Med. 2013;5(167):167sr1. 23303606 10.1126/scitranslmed.3004700
    • (2013) Sci Transl Med , vol.5 , Issue.167
    • Friedman, S.L.1    Sheppard, D.2    Duffield, J.S.3
  • 67
    • 40949159343 scopus 로고    scopus 로고
    • An essential role for fibronectin extra type III domain A in pulmonary fibrosis
    • 18096707, 2267338, F1000 Recommendation
    • Muro AF Moretti FA Moore BB: An essential role for fibronectin extra type III domain A in pulmonary fibrosis. Am J Respir Crit Care Med. 2008;177(6):638-45. 18096707 10.1164/rccm.200708-1291OC 2267338 F1000 Recommendation
    • (2008) Am J Respir Crit Care Med , vol.177 , Issue.6 , pp. 638-645
    • Muro, A.F.1    Moretti, F.A.2    Moore, B.B.3
  • 68
    • 0028984528 scopus 로고
    • The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo
    • 7543902, 2199961
    • Chaponnier C Goethals M Janmey PA: The specific NH2-terminal sequence Ac-EEED of alpha-smooth muscle actin plays a role in polymerization in vitro and in vivo. J Cell Biol. 1995;130(4):887-95. 7543902 10.1083/jcb.130.4.887 2199961
    • (1995) J Cell Biol , vol.130 , Issue.4 , pp. 887-895
    • Chaponnier, C.1    Goethals, M.2    Janmey, P.A.3
  • 69
    • 0037070964 scopus 로고    scopus 로고
    • The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo
    • 11994316, 2173846, F1000 Recommendation
    • Hinz B Gabbiani G Chaponnier C: The NH2-terminal peptide of alpha-smooth muscle actin inhibits force generation by the myofibroblast in vitro and in vivo. J Cell Biol. 2002;157(4):657-63. 11994316 10.1083/jcb.200201049 2173846 F1000 Recommendation
    • (2002) J Cell Biol , vol.157 , Issue.4 , pp. 657-663
    • Hinz, B.1    Gabbiani, G.2    Chaponnier, C.3
  • 70
    • 84938586524 scopus 로고    scopus 로고
    • Stable incorporation of α-smooth muscle actin into stress fibers is dependent on specific tropomyosin isoforms
    • 26147585
    • Prunotto M Bruschi M Gunning P: Stable incorporation of α-smooth muscle actin into stress fibers is dependent on specific tropomyosin isoforms. Cytoskeleton (Hoboken). 2015;72(6):257-67. 26147585 10.1002/cm.21230
    • (2015) Cytoskeleton (Hoboken) , vol.72 , Issue.6 , pp. 257-267
    • Prunotto, M.1    Bruschi, M.2    Gunning, P.3
  • 71
    • 84939547976 scopus 로고    scopus 로고
    • Tropomyosin - master regulator of actin filament function in the cytoskeleton
    • 26240174
    • Gunning PW Hardeman EC Lappalainen P: Tropomyosin - master regulator of actin filament function in the cytoskeleton. J Cell Sci. 2015;128(16):2965-74. 26240174 10.1242/jcs.172502
    • (2015) J Cell Sci , vol.128 , Issue.16 , pp. 2965-2974
    • Gunning, P.W.1    Hardeman, E.C.2    Lappalainen, P.3
  • 72
    • 84929815757 scopus 로고    scopus 로고
    • 1 integrin plays a critical in vivo role in tissue fibrosis
    • 288ra79, 25995225, 4461057
    • 1 integrin plays a critical in vivo role in tissue fibrosis. Sci Transl Med. 2015;7(288):288ra79. 25995225 10.1126/scitranslmed.aaa5094 4461057
    • (2015) Sci Transl Med , vol.7 , Issue.288
    • Reed, N.I.1    Jo, H.2    Chen, C.3
  • 73
    • 84889886646 scopus 로고    scopus 로고
    • v integrin identifies a core molecular pathway that regulates fibrosis in several organs
    • 24216753, 3855865, F1000 Recommendation
    • v integrin identifies a core molecular pathway that regulates fibrosis in several organs. Nat Med. 2013;19(12):1617-24. 24216753 10.1038/nm.3282 3855865 F1000 Recommendation
    • (2013) Nat Med , vol.19 , Issue.12 , pp. 1617-1624
    • Henderson, N.C.1    Arnold, T.D.2    Katamura, Y.3
  • 74
    • 84857236208 scopus 로고    scopus 로고
    • Mitomycin C: biological effects and use in refractive surgery
    • 22157595, F1000 Recommendation
    • Santhiago MR Netto MV Wilson SE: Mitomycin C: biological effects and use in refractive surgery. Cornea. 2012;31(3):311-21. 22157595 10.1097/ICO.0b013e31821e429d F1000 Recommendation
    • (2012) Cornea , vol.31 , Issue.3 , pp. 311-321
    • Santhiago, M.R.1    Netto, M.V.2    Wilson, S.E.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.