Hic-5 is required for myofibroblast differentiation by regulating mechanically dependent MRTF-A nuclear accumulation

Journal of Cell Science

Volumn 129, Issue 4, 2016, Pages 774-787

  Varney, Scott D ^a   Betts, Courtney B ^a,d   Zheng, Rui ^a   Wu, Lei ^a   Hinz, Boris ^b   Zhou, Jiliang ^c   Van De Water, Livingston ^a  

^a ALBANY MEDICAL COLLEGE   (United States)

^b UNIVERSITY OF TORONTO   (Canada)

^c MEDICAL COLLEGE OF GEORGIA   (United States)

^d OREGON HEALTH AND SCIENCE UNIVERSITY   (United States)

Author keywords

Fibrosis; Hic 5; Mechanotransduction; MRTF A; Myofibroblast; Wound healing

Indexed keywords

ALPHA SMOOTH MUSCLE ACTIN; F ACTIN; G ACTIN; HYDROGEN PEROXIDE INDUCIBLE CLONE 5 PROTEIN; MYOCARDIN RELATED TRANSCRIPTION FACTOR A; PROTEIN; SERUM RESPONSE FACTOR; SHORT HAIRPIN RNA; SMAD3 PROTEIN; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA RECEPTOR; UNCLASSIFIED DRUG; CYTOSKELETON PROTEIN; DNA BINDING PROTEIN; LIM PROTEIN; MADH3 PROTEIN, RAT; MYOCARDIN-RELATED TRANSCRIPTION FACTOR-A, RAT; TGFB1I1 PROTEIN, RAT;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ACUTE DISEASE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CELL DIFFERENTIATION; CELL FRACTIONATION; CELL MATURATION; CELL STIMULATION; CELL STRUCTURE; CONTROLLED STUDY; EMBRYO; ENZYME REGULATION; FEMALE; FOCAL ADHESION; GENE DELETION; GENE EXPRESSION REGULATION; GENE OVEREXPRESSION; GENE SILENCING; GENE TRANSLOCATION; GENETIC TRANSFECTION; GRANULATION TISSUE; HUMAN; HUMAN CELL; HYPERTROPHIC SCAR; IN VITRO STUDY; IN VIVO STUDY; LENTIVIRUS INFECTION; MUSCLE CONTRACTILITY; MYOFIBROBLAST; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN INDUCTION; PROTEIN LOCALIZATION; PROTEIN TARGETING; RAT; SIGNAL TRANSDUCTION; STRESS FIBER; UPREGULATION; WOUND; ACTIVE TRANSPORT; ANIMAL; EXTRACELLULAR MATRIX; MECHANOTRANSDUCTION; METABOLISM; PHYSIOLOGY; SCAR; WOUND HEALING;

ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; CELL DIFFERENTIATION; CICATRIX; CYTOSKELETAL PROTEINS; DNA-BINDING PROTEINS; EXTRACELLULAR MATRIX; HUMANS; LIM DOMAIN PROTEINS; MECHANOTRANSDUCTION, CELLULAR; MYOFIBROBLASTS; RATS; SMAD3 PROTEIN; STRESS FIBERS; TRANSCRIPTION FACTORS; TRANSFORMING GROWTH FACTOR BETA; WOUND HEALING;

EID: 84961219361     PISSN: 00219533     EISSN: 14779137     Source Type: Journal    
DOI: 10.1242/jcs.170589     Document Type: Article

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