BRCA1/FANCD2/BRG1-Driven DNA Repair Stabilizes the Differentiation State of Human Mammary Epithelial Cells

Molecular Cell

Volumn 63, Issue 2, 2016, Pages 277-292

  Wang, Hua ^a,b   Bierie, Brian ^c   Li, Andrew G ^a,b   Pathania, Shailja ^a,b   Toomire, Kimberly ^a,b   Dimitrov, Stoil D ^a   Liu, Ben ^a,b   Gelman, Rebecca ^a   Giobbie Hurder, Anita ^a   Feunteun, Jean ^d   Polyak, Kornelia ^a,b,e   Livingston, David M ^a,b  

^a DANA FARBER CANCER INSTITUTE   (United States)

^b HARVARD MEDICAL SCHOOL   (United States)

^c WHITEHEAD INSTITUTE FOR BIOMEDICAL RESEARCH   (United States)

^d Gustave Roussy Comprehensive Cancer Institute   (France)

^e HARVARD STEM CELL INSTITUTE   (United States)

Author keywords

BRCA1; breast cancer; BRG1; cisplatin; crosslink repair; EMT; FANCD2

Indexed keywords

BRCA1 PROTEIN; BRCA2 PROTEIN; BRG1 PROTEIN; DOXYCYCLINE; FANCONI ANEMIA GROUP D2 PROTEIN; FANCONI ANEMIA PROTEIN; NERVE CELL ADHESION MOLECULE; TRANSCRIPTION FACTOR ZEB1; UVOMORULIN; ACETALDEHYDE; BRCA1 PROTEIN, HUMAN; CISPLATIN; DNA HELICASE; FANCD2 PROTEIN, HUMAN; FORMALDEHYDE; NUCLEAR PROTEIN; SMARCA4 PROTEIN, HUMAN; TP63 PROTEIN, HUMAN; TRANSCRIPTION FACTOR; TUMOR SUPPRESSOR PROTEIN;

ARTICLE; BREAST CANCER; BREAST EPITHELIUM CELL; CELL DIFFERENTIATION; CELL PROLIFERATION; CONTROLLED STUDY; DNA CROSS LINKING; DNA DAMAGE; DNA REPAIR; EPITHELIAL MESENCHYMAL TRANSITION; HUMAN; HUMAN CELL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN PROTEIN INTERACTION; PROTEIN STABILITY; BREAST NEOPLASMS; CELL LINE; CELL TRANSFORMATION; DRUG EFFECTS; EPITHELIUM CELL; FEMALE; GENETIC TRANSFECTION; GENETICS; MAMMARY GLAND; METABOLISM; MUTATION; PATHOLOGY; PHENOTYPE; RNA INTERFERENCE; SIGNAL TRANSDUCTION;

ACETALDEHYDE; BRCA1 PROTEIN; BREAST NEOPLASMS; CELL DIFFERENTIATION; CELL LINE; CELL TRANSFORMATION, NEOPLASTIC; CISPLATIN; DNA DAMAGE; DNA HELICASES; DNA REPAIR; EPITHELIAL CELLS; FANCONI ANEMIA COMPLEMENTATION GROUP D2 PROTEIN; FEMALE; FORMALDEHYDE; HUMANS; MAMMARY GLANDS, HUMAN; MUTATION; NUCLEAR PROTEINS; PHENOTYPE; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TRANSCRIPTION FACTORS; TRANSFECTION; TUMOR SUPPRESSOR PROTEINS;

EID: 84978496791     PISSN: 10972765     EISSN: 10974164     Source Type: Journal    
DOI: 10.1016/j.molcel.2016.05.038     Document Type: Article

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