Ophiopogonin B induces apoptosis, mitotic catastrophe and autophagy in A549 cells

International Journal of Oncology

Volumn 49, Issue 1, 2016, Pages 316-324

  Chen, Meijuan ^a,b   Guo, Yuanyuan ^a,b   Zhao, Ruolin ^a   Wang, Xiaoxia ^b   Jiang, Miao ^a   Fu, Haian ^c   Zhang, Xu ^b  

^a Pre Clinical Medicine College   (United States)

^b NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Apoptosis; Autophagy; Cell cycle; Histone H3; Mitotic catastrophe; Ophiopogonin B

Indexed keywords

CASPASE 3; HISTONE H3; OPHIOPOGONIN B; PROTEIN BAX; PROTEIN BCL 2; SAPONIN; SURVIVIN; UNCLASSIFIED DRUG; X LINKED INHIBITOR OF APOPTOSIS; HERBACEOUS AGENT; SMALL INTERFERING RNA; SPIROSTAN DERIVATIVE;

A549 CELL LINE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CELL CYCLE ARREST; CELL PROLIFERATION; CELL VIABILITY; CELLULAR DISTRIBUTION; CONCENTRATION RESPONSE; CONTROLLED STUDY; DNA FRAGMENTATION; DRUG EFFICACY; DRUG MECHANISM; G2 PHASE CELL CYCLE CHECKPOINT; LYSOSOME; MOUSE; NON SMALL CELL LUNG CANCER; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN EXPRESSION; PROTEIN PHOSPHORYLATION; A-549 CELL LINE; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE CHECKPOINT; DRUG EFFECTS; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; HUMAN; MITOSIS; PATHOLOGY;

A549 CELLS; APOPTOSIS; AUTOPHAGY; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE CHECKPOINTS; CELL PROLIFERATION; DRUGS, CHINESE HERBAL; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MITOSIS; RNA, SMALL INTERFERING; SAPONINS; SPIROSTANS; XENOGRAFT MODEL ANTITUMOR ASSAYS;

EID: 84978401507     PISSN: 10196439     EISSN: 17912423     Source Type: Journal    
DOI: 10.3892/ijo.2016.3514     Document Type: Article

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