Ophiopogonin B-induced autophagy in non-small cell lung cancer cells via inhibition of the PI3K/Akt signaling pathway

Oncology Reports

Volumn 29, Issue 2, 2013, Pages 430-436

  Chen, Meijuan ^a   Du, Yuhong ^b   Qui, Min ^b   Wang, Mingyan ^a   Chen, Kejun ^b   Huang, Zhenzhou ^a   Jiang, Miao ^a   Xiong, Fei ^a   Chen, Jianping ^a   Zhou, Jing ^a   Jiang, Fengrong ^a   Yin, Lian ^a   Tang, Yuping ^a   Ye, Lihong ^a   Zhan, Zhen ^a   Duan, Jin Ao ^a   Fu, Hai An ^b   Zhang, Xu ^a  

^a NANJING UNIVERSITY OF CHINESE MEDICINE   (China)

^b EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Autophagy; Natural medicines; Non small cell lung cancer; Ophiopogonin B; PI3K Akt mTOR

Indexed keywords

2 MORPHOLINO 8 PHENYLCHROMONE; CASPASE 3; INSULIN; LIPOCORTIN 5; MAMMALIAN TARGET OF RAPAMYCIN; MICROTUBULE ASSOCIATED PROTEIN 1; OPHIOPOGON JAPONICUS EXTRACT; OPHIOPOGONIN B; PHOSPHATIDYLINOSITOL 3 KINASE; PLANT EXTRACT; PROPIDIUM IODIDE; PROTEIN KINASE B; RAPAMYCIN; SERINE; THREONINE; UNCLASSIFIED DRUG;

ANTINEOPLASTIC ACTIVITY; APOPTOSIS; ARTICLE; AUTOPHAGY; CANCER CELL CULTURE; CELL CYCLE G0 PHASE; CELL CYCLE G1 PHASE; CELL GROWTH; CELL NUCLEUS; CELL VACUOLE; CONTROLLED STUDY; CORRELATION ANALYSIS; CYTOPLASM; DRUG POTENTIATION; DRUG STRUCTURE; ENZYME ACTIVATION; ENZYME DEGRADATION; ENZYME INHIBITION; ENZYME PHOSPHORYLATION; FLOW CYTOMETRY; HUMAN; HUMAN CELL; LUNG NON SMALL CELL CANCER; OPHIOPOGON JAPONICUS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL TRANSDUCTION; TRANSMISSION ELECTRON MICROSCOPY;

AUTOPHAGY; CARCINOMA, NON-SMALL-CELL LUNG; CELL CYCLE CHECKPOINTS; CELL LINE, TUMOR; CELL PROLIFERATION; CYTOPLASM; HUMANS; LUNG NEOPLASMS; MICROTUBULE-ASSOCIATED PROTEINS; PHOSPHATIDYLINOSITOL 3-KINASES; PLANT EXTRACTS; PROTO-ONCOGENE PROTEINS C-AKT; SAPONINS; SIGNAL TRANSDUCTION; SPIROSTANS; VACUOLES;

EID: 84872788950     PISSN: 1021335X     EISSN: 17912431     Source Type: Journal    
DOI: 10.3892/or.2012.2131     Document Type: Article

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