Yin Yang-1 suppresses invasion and metastasis of pancreatic ductal adenocarcinoma by downregulating MMP10 in a MUC4/ErbB2/p38/MEF2C-dependent mechanism

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Zhang, Jing Jing ^a,b   Zhu, Yi ^a,b   Xie, Kun Ling ^c   Peng, Yun Peng ^c   Tao, Jin Qiu ^c   Tang, Jie ^c   Li, Zheng ^c   Xu, Ze Kuan ^a,b   Dai, Cun Cai ^a   Qian, Zhu Yin ^a   Jiang, Kui Rong ^a   Wu, Jun Li ^a   Gao, Wen Tao ^a   Du, Qing ^a,b   Miao, Yi ^a,b  

^a THE FIRST AFFILIATED HOSPITAL OF NANJING MEDICAL UNIVERSITY   (China)

^b Jiangsu Province Academy of Clinical Medicine   (China)

^c NANJING MEDICAL UNIVERSITY   (China)

Author keywords

MEF2C; Metastasis; MMP10; MUC4; Pancreatic ductal adenocarcinoma; Yin Yang 1

Indexed keywords

BIOLOGICAL MARKER; CHOLECYSTOKININ OCTAPEPTIDE; EPIDERMAL GROWTH FACTOR RECEPTOR 2; MITOGEN ACTIVATED PROTEIN KINASE P38; MUCIN 4; MYOCYTE ENHANCER FACTOR 2; STROMELYSIN 2; TRANSCRIPTION FACTOR YY1; ERBB2 PROTEIN, HUMAN; MEF2C PROTEIN, HUMAN; MMP10 PROTEIN, HUMAN; MUC4 PROTEIN, HUMAN; YY1 PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CANCER CELL LINE; CELL MIGRATION ASSAY; CELL PROLIFERATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; GENE EXPRESSION ASSAY; HUMAN; HUMAN CELL; HUMAN TISSUE; IMMUNOHISTOCHEMISTRY; LUCIFERASE ASSAY; MAJOR CLINICAL STUDY; METASTASIS; MOUSE; NONHUMAN; OUTCOME ASSESSMENT; PANCREAS ADENOCARCINOMA; PROTEIN DETERMINATION; PROTEIN EXPRESSION; PROTEIN FUNCTION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; SIGNAL TRANSDUCTION; STATISTICAL ANALYSIS; TUMOR GROWTH; TUMOR XENOGRAFT; WESTERN BLOTTING; ADULT; AGED; ANIMAL; DRUG SCREENING; GENE EXPRESSION REGULATION; GENETICS; LIVER TUMOR; LUNG TUMOR; MALE; METABOLISM; MIDDLE AGED; MORTALITY; NUDE MOUSE; PANCREAS; PANCREAS CARCINOMA; PANCREAS TUMOR; PATHOLOGY; SECONDARY; SURVIVAL; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; ANIMALS; CARCINOMA, PANCREATIC DUCTAL; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; LUNG NEOPLASMS; MALE; MATRIX METALLOPROTEINASE 10; MEF2 TRANSCRIPTION FACTORS; MICE; MICE, NUDE; MIDDLE AGED; MUCIN-4; P38 MITOGEN-ACTIVATED PROTEIN KINASES; PANCREAS; PANCREATIC NEOPLASMS; RECEPTOR, ERBB-2; SIGNAL TRANSDUCTION; SURVIVAL ANALYSIS; XENOGRAFT MODEL ANTITUMOR ASSAYS; YY1 TRANSCRIPTION FACTOR;

EID: 84902074029     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-130     Document Type: Article

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