Safety assessment of a natural tomato oleoresin containing high amounts of Z-isomers of lycopene prepared with supercritical carbon dioxide

Journal of the Science of Food and Agriculture

Volumn 97, Issue 3, 2017, Pages 1027-1033

  Honda, Masaki ^a   Higashiura, Takuma ^a   Fukaya, Tetsuya ^a  

^a KAGOME CO   (Japan)

Author keywords

4 week repeated dose oral toxicity test; acute oral toxicity test; bacterial reverse mutation assay; supercritical carbon dioxide; tomato; Z isomers of lycopene

Indexed keywords

CARBON DIOXIDE; CAROTENOID; FOOD ADDITIVE; LYCOPENE; OLEORESINS; PLANT EXTRACT;

ADVERSE EFFECTS; ANIMAL; CHEMISTRY; DIETARY SUPPLEMENT; ENZYMOLOGY; FEMALE; FOOD HANDLING; FRUIT; ISOLATION AND PURIFICATION; LD50; LIVER MICROSOME; MALE; METABOLISM; MUTAGEN TESTING; RAT; STEREOISOMERISM; SUPERCRITICAL FLUID CHROMATOGRAPHY; TOMATO; TOXICITY TESTING; WISTAR RAT;

ANIMALS; CARBON DIOXIDE; CAROTENOIDS; CHROMATOGRAPHY, SUPERCRITICAL FLUID; DIETARY SUPPLEMENTS; FEMALE; FOOD ADDITIVES; FOOD HANDLING; FRUIT; LETHAL DOSE 50; LYCOPERSICON ESCULENTUM; MALE; MICROSOMES, LIVER; MUTAGENICITY TESTS; PLANT EXTRACTS; RATS; RATS, WISTAR; STEREOISOMERISM; TOXICITY TESTS, ACUTE; TOXICITY TESTS, SUBACUTE;

EID: 84978196682     PISSN: 00225142     EISSN: 10970010     Source Type: Journal    
DOI: 10.1002/jsfa.7830     Document Type: Article

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