Thirteen-week oral toxicity study of synthetic lycopene products in rats

Food and Chemical Toxicology

Volumn 40, Issue 11, 2002, Pages 1581-1588

  Mellert, W ^a   Deckardt, K ^a   Gembardt, C ^a   Schulte, S ^a   Ravenzwaay, B Van ^a   Slesinski, R S ^b  

^a BASF SE   (Germany)

^b ENVIRON INTERNATIONAL CORPORATION   (United States)

Author keywords

Antioxidant' dietary supplement; Carotenoids; CAS No. 502 65 8; Lycopene; Rats; Subchronic toxicity

Indexed keywords

LYCOPENE;

ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BODY WEIGHT; CONTROLLED STUDY; DOSE RESPONSE; EVALUATION; FEEDING; FEMALE; FOOD INTAKE; HEMATOLOGY; HISTOPATHOLOGY; MALE; MORTALITY; NONHUMAN; OPEN FIELD TEST; OPHTHALMOSCOPY; ORGAN WEIGHT; RAT; TOXICITY TESTING; URINALYSIS; WEIGHT GAIN;

ADMINISTRATION, ORAL; ANIMALS; BODY WEIGHT; CAROTENOIDS; CRYSTALLIZATION; DIETARY SUPPLEMENTS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; FEMALE; MAGNESIUM; MALE; NO-OBSERVED-ADVERSE-EFFECT LEVEL; OPHTHALMOSCOPY; ORGAN SIZE; RATS; RATS, WISTAR;

RATTUS NORVEGICUS;

EID: 0036045793     PISSN: 02786915     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0278-6915(02)00113-8     Document Type: Article

References (6)

1. Tomato lycopene and low-density lipoprotein oxidation: A human dietary intervention study
2. Lycopene as the most effective biological carotenoid singlet oxygen quencher
3. Role of lycopene as antioxidant carotenoid in the prevention of chronic diseases: A review
4. Lycopene uptake and tissue disposition in male and female rats