-
1
-
-
77957883342
-
The Hippo signaling pathway in development and cancer
-
Pan D. The Hippo signaling pathway in development and cancer. Dev Cell. 2010;19(4):491-505.
-
(2010)
Dev Cell
, vol.19
, Issue.4
, pp. 491-505
-
-
Pan, D.1
-
3
-
-
81055140859
-
The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells
-
Cordenonsi M, Zanconato F, Azzolin L, Forcato M, Rosato A, Frasson C, Inui M, Montagner M, Parenti AR, Poletti A, et al. The Hippo transducer TAZ confers cancer stem cell-related traits on breast cancer cells. Cell. 2011;147(4):759-72.
-
(2011)
Cell
, vol.147
, Issue.4
, pp. 759-772
-
-
Cordenonsi, M.1
Zanconato, F.2
Azzolin, L.3
Forcato, M.4
Rosato, A.5
Frasson, C.6
Inui, M.7
Montagner, M.8
Parenti, A.R.9
Poletti, A.10
-
4
-
-
79955638768
-
TAZ is a novel oncogene in non-small cell lung cancer
-
Zhou Z, Hao Y, Liu N, Raptis L, Tsao MS, Yang X. TAZ is a novel oncogene in non-small cell lung cancer. Oncogene. 2011;30(18):2181-6.
-
(2011)
Oncogene
, vol.30
, Issue.18
, pp. 2181-2186
-
-
Zhou, Z.1
Hao, Y.2
Liu, N.3
Raptis, L.4
Tsao, M.S.5
Yang, X.6
-
5
-
-
77954770827
-
Targeting YAP and Hippo signaling pathway in liver cancer
-
Liu AM, Xu MZ, Chen J, Poon RT, Luk JM. Targeting YAP and Hippo signaling pathway in liver cancer. Expert Opin Ther Targets. 2010;14(8):855-68.
-
(2010)
Expert Opin Ther Targets
, vol.14
, Issue.8
, pp. 855-868
-
-
Liu, A.M.1
Xu, M.Z.2
Chen, J.3
Poon, R.T.4
Luk, J.M.5
-
6
-
-
84873336472
-
Intestinal regeneration: YAP-tumor suppressor and oncoprotein?
-
Li VS, Clevers H. Intestinal regeneration: YAP-tumor suppressor and oncoprotein? Curr Biol. 2013;23(3):R110-2.
-
(2013)
Curr Biol
, vol.23
, Issue.3
, pp. R110-R112
-
-
Li, V.S.1
Clevers, H.2
-
7
-
-
54049121368
-
Yes-associated protein (YAP) functions as a tumor suppressor in breast
-
Yuan M, Tomlinson V, Lara R, Holliday D, Chelala C, Harada T, Gangeswaran R, Manson-Bishop C, Smith P, Danovi SA, et al. Yes-associated protein (YAP) functions as a tumor suppressor in breast. Cell Death Differ. 2008;15(11):1752-9.
-
(2008)
Cell Death Differ
, vol.15
, Issue.11
, pp. 1752-1759
-
-
Yuan, M.1
Tomlinson, V.2
Lara, R.3
Holliday, D.4
Chelala, C.5
Harada, T.6
Gangeswaran, R.7
Manson-Bishop, C.8
Smith, P.9
Danovi, S.A.10
-
8
-
-
30344445706
-
The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis
-
Hamaratoglu F, Willecke M, Kango-Singh M, Nolo R, Hyun E, Tao C, Jafar-Nejad H, Halder G. The tumour-suppressor genes NF2/Merlin and Expanded act through Hippo signalling to regulate cell proliferation and apoptosis. Nat Cell Biol. 2006;8(1):27-36.
-
(2006)
Nat Cell Biol
, vol.8
, Issue.1
, pp. 27-36
-
-
Hamaratoglu, F.1
Willecke, M.2
Kango-Singh, M.3
Nolo, R.4
Hyun, E.5
Tao, C.6
Jafar-Nejad, H.7
Halder, G.8
-
9
-
-
84884291548
-
Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2
-
Yin F, Yu J, Zheng Y, Chen Q, Zhang N, Pan D. Spatial organization of Hippo signaling at the plasma membrane mediated by the tumor suppressor Merlin/NF2. Cell. 2013;154(6):1342-55.
-
(2013)
Cell
, vol.154
, Issue.6
, pp. 1342-1355
-
-
Yin, F.1
Yu, J.2
Zheng, Y.3
Chen, Q.4
Zhang, N.5
Pan, D.6
-
10
-
-
33845426464
-
The Drosophila RASSF homolog antagonizes the Hippo pathway
-
Polesello C, Huelsmann S, Brown NH, Tapon N. The Drosophila RASSF homolog antagonizes the Hippo pathway. Curr Biol CB. 2006;16(24):2459-65.
-
(2006)
Curr Biol CB
, vol.16
, Issue.24
, pp. 2459-2465
-
-
Polesello, C.1
Huelsmann, S.2
Brown, N.H.3
Tapon, N.4
-
11
-
-
73349136609
-
Hippo pathway-dependent and-independent roles of RASSF6
-
ra59
-
Ikeda M, Kawata A, Nishikawa M, Tateishi Y, Yamaguchi M, Nakagawa K, Hirabayashi S, Bao Y, Hidaka S, Hirata Y. Hippo pathway-dependent and-independent roles of RASSF6. Sci Signal. 2009;2(90):ra59.
-
(2009)
Sci Signal
, vol.2
, Issue.90
-
-
Ikeda, M.1
Kawata, A.2
Nishikawa, M.3
Tateishi, Y.4
Yamaguchi, M.5
Nakagawa, K.6
Hirabayashi, S.7
Bao, Y.8
Hidaka, S.9
Hirata, Y.10
-
12
-
-
79953211893
-
The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2
-
Guo C, Zhang X, Pfeifer GP. The tumor suppressor RASSF1A prevents dephosphorylation of the mammalian STE20-like kinases MST1 and MST2. J Biol Chem. 2011;286(8):6253-61.
-
(2011)
J Biol Chem
, vol.286
, Issue.8
, pp. 6253-6261
-
-
Guo, C.1
Zhang, X.2
Pfeifer, G.P.3
-
13
-
-
78049359250
-
Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis
-
Park J, Kang SI, Lee SY, Zhang XF, Kim MS, Beers LF, Lim DS, Avruch J, Kim HS, Lee SB. Tumor suppressor ras association domain family 5 (RASSF5/NORE1) mediates death receptor ligand-induced apoptosis. J Biol Chem. 2010;285(45):35029-38.
-
(2010)
J Biol Chem
, vol.285
, Issue.45
, pp. 35029-35038
-
-
Park, J.1
Kang, S.I.2
Lee, S.Y.3
Zhang, X.F.4
Kim, M.S.5
Beers, L.F.6
Lim, D.S.7
Avruch, J.8
Kim, H.S.9
Lee, S.B.10
-
14
-
-
76249109900
-
Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and expanded
-
Yu JZ, Zheng YG, Dong JX, Klusza S, Deng WM, Pan DJ. Kibra functions as a tumor suppressor protein that regulates Hippo signaling in conjunction with Merlin and expanded. Dev Cell. 2010;18(2):288-99.
-
(2010)
Dev Cell
, vol.18
, Issue.2
, pp. 288-299
-
-
Yu, J.Z.1
Zheng, Y.G.2
Dong, J.X.3
Klusza, S.4
Deng, W.M.5
Pan, D.J.6
-
15
-
-
84876158761
-
KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals
-
Moleirinho S, Chang N, Sims AH, Tilston-Lunel AM, Angus L, Steele A, Boswell V, Barnett SC, Ormandy C, Faratian D, et al. KIBRA exhibits MST-independent functional regulation of the Hippo signaling pathway in mammals. Oncogene. 2013;32(14):1821-30.
-
(2013)
Oncogene
, vol.32
, Issue.14
, pp. 1821-1830
-
-
Moleirinho, S.1
Chang, N.2
Sims, A.H.3
Tilston-Lunel, A.M.4
Angus, L.5
Steele, A.6
Boswell, V.7
Barnett, S.C.8
Ormandy, C.9
Faratian, D.10
-
16
-
-
84891748709
-
The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment
-
Johnson R, Halder G. The two faces of Hippo: targeting the Hippo pathway for regenerative medicine and cancer treatment. Nat Rev Drug Discovery. 2014;13(1):63-79.
-
(2014)
Nat Rev Drug Discovery
, vol.13
, Issue.1
, pp. 63-79
-
-
Johnson, R.1
Halder, G.2
-
17
-
-
73549095761
-
A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF beta-TRCP
-
Zhao B, Li L, Tumaneng K, Wang CY, Guan KL. A coordinated phosphorylation by Lats and CK1 regulates YAP stability through SCF beta-TRCP. Genes Dev. 2010;24(1):72-85.
-
(2010)
Genes Dev
, vol.24
, Issue.1
, pp. 72-85
-
-
Zhao, B.1
Li, L.2
Tumaneng, K.3
Wang, C.Y.4
Guan, K.L.5
-
18
-
-
84864387121
-
The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFbeta-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition
-
Huang W, Lv X, Liu C, Zha Z, Zhang H, Jiang Y, Xiong Y, Lei QY, Guan KL. The N-terminal phosphodegron targets TAZ/WWTR1 protein for SCFbeta-TrCP-dependent degradation in response to phosphatidylinositol 3-kinase inhibition. J Biol Chem. 2012;287(31):26245-53.
-
(2012)
J Biol Chem
, vol.287
, Issue.31
, pp. 26245-26253
-
-
Huang, W.1
Lv, X.2
Liu, C.3
Zha, Z.4
Zhang, H.5
Jiang, Y.6
Xiong, Y.7
Lei, Q.Y.8
Guan, K.L.9
-
19
-
-
84922911896
-
NDR functions as a physiological YAP1 kinase in the intestinal epithelium
-
Zhang L, Tang FY, Terracciano L, Hynx D, Kohler R, Bichet S, Hess D, Cron P, Hemmings BA, Hergovich A, et al. NDR functions as a physiological YAP1 kinase in the intestinal epithelium. Curr Biol. 2015;25(3):296-305.
-
(2015)
Curr Biol
, vol.25
, Issue.3
, pp. 296-305
-
-
Zhang, L.1
Tang, F.Y.2
Terracciano, L.3
Hynx, D.4
Kohler, R.5
Bichet, S.6
Hess, D.7
Cron, P.8
Hemmings, B.A.9
Hergovich, A.10
-
20
-
-
79953153876
-
PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ
-
Liu CY, Lv X, Li T, Xu Y, Zhou X, Zhao S, Xiong Y, Lei QY, Guan KL. PP1 cooperates with ASPP2 to dephosphorylate and activate TAZ. J Biol Chem. 2011;286(7):5558-66.
-
(2011)
J Biol Chem
, vol.286
, Issue.7
, pp. 5558-5566
-
-
Liu, C.Y.1
Lv, X.2
Li, T.3
Xu, Y.4
Zhou, X.5
Zhao, S.6
Xiong, Y.7
Lei, Q.Y.8
Guan, K.L.9
-
21
-
-
77954772169
-
JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis
-
Tomlinson V, Gudmundsdottir K, Luong P, Leung KY, Knebel A, Basu S. JNK phosphorylates Yes-associated protein (YAP) to regulate apoptosis. Cell Death Dis. 2010;1(2):e29.
-
(2010)
Cell Death Dis
, vol.1
, Issue.2
-
-
Tomlinson, V.1
Gudmundsdottir, K.2
Luong, P.3
Leung, K.Y.4
Knebel, A.5
Basu, S.6
-
22
-
-
84871576111
-
Beta-catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis
-
Rosenbluh J, Nijhawan D, Cox AG, Li XN, Neal JT, Schafer EJ, Zack TI, Wang XX, Tsherniak A, Schinzel AC, et al. Beta-catenin-driven cancers require a YAP1 transcriptional complex for survival and tumorigenesis. Cell. 2012;151(7):1457-73.
-
(2012)
Cell
, vol.151
, Issue.7
, pp. 1457-1473
-
-
Rosenbluh, J.1
Nijhawan, D.2
Cox, A.G.3
Li, X.N.4
Neal, J.T.5
Schafer, E.J.6
Zack, T.I.7
Wang, X.X.8
Tsherniak, A.9
Schinzel, A.C.10
-
23
-
-
84939989486
-
c-Abl antagonizes the YAP oncogenic function
-
Keshet R, Adler J, Lax IR, Shanzer M, Porat Z, Reuven N, Shaul Y. c-Abl antagonizes the YAP oncogenic function. Cell Death Differ. 2015;22(6):935-45.
-
(2015)
Cell Death Differ
, vol.22
, Issue.6
, pp. 935-945
-
-
Keshet, R.1
Adler, J.2
Lax, I.R.3
Shanzer, M.4
Porat, Z.5
Reuven, N.6
Shaul, Y.7
-
24
-
-
84865840957
-
PTPN14 is required for the density-dependent control of YAP1
-
Wang WQ, Huang J, Wang X, Yuan JS, Li X, Feng L, Park JI, Chen JJ. PTPN14 is required for the density-dependent control of YAP1. Genes Dev. 2012;26(17):1959-71.
-
(2012)
Genes Dev
, vol.26
, Issue.17
, pp. 1959-1971
-
-
Wang, W.Q.1
Huang, J.2
Wang, X.3
Yuan, J.S.4
Li, X.5
Feng, L.6
Park, J.I.7
Chen, J.J.8
-
25
-
-
84866145624
-
Homeodomain-interacting protein kinase regulates Hippo pathway-dependent tissue growth
-
Poon CL, Zhang X, Lin JI, Manning SA, Harvey KF. Homeodomain-interacting protein kinase regulates Hippo pathway-dependent tissue growth. Curr Biol CB. 2012;22(17):1587-94.
-
(2012)
Curr Biol CB
, vol.22
, Issue.17
, pp. 1587-1594
-
-
Poon, C.L.1
Zhang, X.2
Lin, J.I.3
Manning, S.A.4
Harvey, K.F.5
-
26
-
-
42449132938
-
A Hippo in the ointment: MST signalling beyond the fly
-
Matallanas D, Romano D, Hamilton G, Kolch W, O'Neill E. A Hippo in the ointment: MST signalling beyond the fly. Cell Cycle. 2008;7(7):879-84.
-
(2008)
Cell Cycle
, vol.7
, Issue.7
, pp. 879-884
-
-
Matallanas, D.1
Romano, D.2
Hamilton, G.3
Kolch, W.4
O'Neill, E.5
-
27
-
-
80755136770
-
Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway
-
Boggiano JC, Vanderzalm PJ, Fehon RG. Tao-1 phosphorylates Hippo/MST kinases to regulate the Hippo-Salvador-Warts tumor suppressor pathway. Dev Cell. 2011;21(5):888-95.
-
(2011)
Dev Cell
, vol.21
, Issue.5
, pp. 888-895
-
-
Boggiano, J.C.1
Vanderzalm, P.J.2
Fehon, R.G.3
-
28
-
-
35649004861
-
Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation
-
Jang SW, Yang SJ, Srinivasan S, Ye K. Akt phosphorylates MstI and prevents its proteolytic activation, blocking FOXO3 phosphorylation and nuclear translocation. J Biol Chem. 2007;282(42):30836-44.
-
(2007)
J Biol Chem
, vol.282
, Issue.42
, pp. 30836-30844
-
-
Jang, S.W.1
Yang, S.J.2
Srinivasan, S.3
Ye, K.4
-
29
-
-
84863618427
-
Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1
-
Collak FK, Yagiz K, Luthringer DJ, Erkaya B, Cinar B. Threonine-120 phosphorylation regulated by phosphoinositide-3-kinase/Akt and mammalian target of rapamycin pathway signaling limits the antitumor activity of mammalian sterile 20-like kinase 1. J Biol Chem. 2012;287(28):23698-709.
-
(2012)
J Biol Chem
, vol.287
, Issue.28
, pp. 23698-23709
-
-
Collak, F.K.1
Yagiz, K.2
Luthringer, D.J.3
Erkaya, B.4
Cinar, B.5
-
30
-
-
77949909616
-
c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82
-
Bi WZ, Xiao L, Jia YF, Wu JB, Xie Q, Ren J, Ji GJ, Yuan ZQ. c-Jun N-terminal kinase enhances MST1-mediated pro-apoptotic signaling through phosphorylation at serine 82. J Biol Chem. 2010;285(9):6259-64.
-
(2010)
J Biol Chem
, vol.285
, Issue.9
, pp. 6259-6264
-
-
Bi, W.Z.1
Xiao, L.2
Jia, Y.F.3
Wu, J.B.4
Xie, Q.5
Ren, J.6
Ji, G.J.7
Yuan, Z.Q.8
-
31
-
-
79959960788
-
The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death
-
Xiao L, Chen D, Hu P, Wu J, Liu W, Zhao Y, Cao M, Fang Y, Bi W, Zheng Z, et al. The c-Abl-MST1 signaling pathway mediates oxidative stress-induced neuronal cell death. J Neurosci. 2011;31(26):9611-9.
-
(2011)
J Neurosci
, vol.31
, Issue.26
, pp. 9611-9619
-
-
Xiao, L.1
Chen, D.2
Hu, P.3
Wu, J.4
Liu, W.5
Zhao, Y.6
Cao, M.7
Fang, Y.8
Bi, W.9
Zheng, Z.10
-
32
-
-
84901437983
-
Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma
-
Tu KS, Yang W, Li C, Zheng X, Lu ZT, Guo C, Yao YM, Liu QG. Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma. Molecular Cancer. 2014;17(13):110.
-
(2014)
Molecular Cancer.
, vol.17
, Issue.13
, pp. 110
-
-
Tu, K.S.1
Yang, W.2
Li, C.3
Zheng, X.4
Lu, Z.T.5
Guo, C.6
Yao, Y.M.7
Liu, Q.G.8
-
33
-
-
79953204984
-
Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected]
-
Ho KC, Zhou Z, She YM, Chun A, Cyr TD, Yang X. Itch E3 ubiquitin ligase regulates large tumor suppressor 1 stability [corrected]. Proc Natl Acad Sci USA. 2011;108(12):4870-5.
-
(2011)
Proc Natl Acad Sci USA
, vol.108
, Issue.12
, pp. 4870-4875
-
-
Ho, K.C.1
Zhou, Z.2
She, Y.M.3
Chun, A.4
Cyr, T.D.5
Yang, X.6
-
34
-
-
79952266588
-
Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH Is sufficient to promote tumorigenicity
-
Salah Z, Melino G, Aqeilan RI. Negative regulation of the Hippo pathway by E3 ubiquitin ligase ITCH Is sufficient to promote tumorigenicity. Cancer Res. 2011;71(5):2010-20.
-
(2011)
Cancer Res
, vol.71
, Issue.5
, pp. 2010-2020
-
-
Salah, Z.1
Melino, G.2
Aqeilan, R.I.3
-
35
-
-
84904266769
-
Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the Hippo pathway kinases Lats1 and 2 in the nucleus
-
Li W, Cooper J, Zhou L, Yang C, Erdjument-Bromage H, Zagzag D, Snuderl M, Ladanyi M, Hanemann CO, Zhou P, et al. Merlin/NF2 loss-driven tumorigenesis linked to CRL4(DCAF1)-mediated inhibition of the Hippo pathway kinases Lats1 and 2 in the nucleus. Cancer Cell. 2014;26(1):48-60.
-
(2014)
Cancer Cell
, vol.26
, Issue.1
, pp. 48-60
-
-
Li, W.1
Cooper, J.2
Zhou, L.3
Yang, C.4
Erdjument-Bromage, H.5
Zagzag, D.6
Snuderl, M.7
Ladanyi, M.8
Hanemann, C.O.9
Zhou, P.10
-
36
-
-
84875710846
-
WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells
-
Yeung B, Ho KC, Yang X. WWP1 E3 ligase targets LATS1 for ubiquitin-mediated degradation in breast cancer cells. PLoS One. 2013;8(4):e61027.
-
(2013)
PLoS One
, vol.8
, Issue.4
-
-
Yeung, B.1
Ho, K.C.2
Yang, X.3
-
37
-
-
84926137241
-
Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase
-
Ma B, Chen Y, Chen L, Cheng H, Mu C, Li J, Gao R, Zhou C, Cao L, Liu J, et al. Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase. Nat Cell Biol. 2015;17(1):95-103.
-
(2015)
Nat Cell Biol
, vol.17
, Issue.1
, pp. 95-103
-
-
Ma, B.1
Chen, Y.2
Chen, L.3
Cheng, H.4
Mu, C.5
Li, J.6
Gao, R.7
Zhou, C.8
Cao, L.9
Liu, J.10
-
38
-
-
84878596483
-
Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth
-
Lignitto L, Arcella A, Sepe M, Rinaldi L, Donne RD, Gallo A, Stefan E, Bachmann VA, Oliva MA, Tiziana Storlazzi C, et al. Proteolysis of MOB1 by the ubiquitin ligase praja2 attenuates Hippo signalling and supports glioblastoma growth. Nat Commun. 2013;4:1822.
-
(2013)
Nat Commun.
, vol.4
, pp. 1822
-
-
Lignitto, L.1
Arcella, A.2
Sepe, M.3
Rinaldi, L.4
Donne, R.D.5
Gallo, A.6
Stefan, E.7
Bachmann, V.A.8
Oliva, M.A.9
Tiziana Storlazzi, C.10
-
39
-
-
84901341003
-
The E3 Ligase CHIP. Insights into its structure and regulation
-
Paul I, Ghosh MK. The E3 Ligase CHIP. Insights into its structure and regulation. BioMed Res Int. 2014;2014.
-
(2014)
BioMed Res Int. 2014
-
-
Paul, I.1
Ghosh, M.K.2
-
40
-
-
84907507646
-
CYLD negatively regulates Hippo signaling by limiting Hpo phosphorylation in Drosophila
-
Chen Y, Wang Z, Wang P, Li D, Zhou J, Wu S. CYLD negatively regulates Hippo signaling by limiting Hpo phosphorylation in Drosophila. Biochem Biophys Res Commun. 2014;452(3):808-12.
-
(2014)
Biochem Biophys Res Commun
, vol.452
, Issue.3
, pp. 808-812
-
-
Chen, Y.1
Wang, Z.2
Wang, P.3
Li, D.4
Zhou, J.5
Wu, S.6
-
41
-
-
57749084642
-
PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop
-
Lapi E, Di Agostino S, Donzelli S, Gal H, Domany E, Rechavi G, Pandolfi PP, Givol D, Strano S, Lu X, et al. PML, YAP, and p73 are components of a proapoptotic autoregulatory feedback loop. Mol Cell. 2008;32(6):803-14.
-
(2008)
Mol Cell
, vol.32
, Issue.6
, pp. 803-814
-
-
Lapi, E.1
Agostino, S.2
Donzelli, S.3
Gal, H.4
Domany, E.5
Rechavi, G.6
Pandolfi, P.P.7
Givol, D.8
Strano, S.9
Lu, X.10
-
42
-
-
84862644867
-
A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents
-
Hata S, Hirayama J, Kajiho H, Nakagawa K, Hata Y, Katada T, Furutani-Seiki M, Nishina H. A novel acetylation cycle of transcription co-activator Yes-associated protein that is downstream of Hippo pathway is triggered in response to SN2 alkylating agents. J Biol Chem. 2012;287(26):22089-98.
-
(2012)
J Biol Chem
, vol.287
, Issue.26
, pp. 22089-22098
-
-
Hata, S.1
Hirayama, J.2
Kajiho, H.3
Nakagawa, K.4
Hata, Y.5
Katada, T.6
Furutani-Seiki, M.7
Nishina, H.8
-
43
-
-
84896400883
-
SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma
-
Mao B, Hu F, Cheng J, Wang P, Xu M, Yuan F, Meng S, Wang Y, Yuan Z, Bi W. SIRT1 regulates YAP2-mediated cell proliferation and chemoresistance in hepatocellular carcinoma. Oncogene. 2014;33(11):1468-74.
-
(2014)
Oncogene
, vol.33
, Issue.11
, pp. 1468-1474
-
-
Mao, B.1
Hu, F.2
Cheng, J.3
Wang, P.4
Xu, M.5
Yuan, F.6
Meng, S.7
Wang, Y.8
Yuan, Z.9
Bi, W.10
-
44
-
-
84880945084
-
Control of the Hippo pathway by Set7-dependent methylation of Yap
-
Oudhoff MJ, Freeman SA, Couzens AL, Antignano F, Kuznetsova E, Min PH, Northrop JP, Lehnertz B, Barsyte-Lovejoy D, Vedadi M, et al. Control of the Hippo pathway by Set7-dependent methylation of Yap. Dev Cell. 2013;26(2):188-94.
-
(2013)
Dev Cell
, vol.26
, Issue.2
, pp. 188-194
-
-
Oudhoff, M.J.1
Freeman, S.A.2
Couzens, A.L.3
Antignano, F.4
Kuznetsova, E.5
Min, P.H.6
Northrop, J.P.7
Lehnertz, B.8
Barsyte-Lovejoy, D.9
Vedadi, M.10
-
45
-
-
84902083075
-
Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers
-
Cottini F, Hideshima T, Xu C, Sattler M, Dori M, Agnelli L, ten Hacken E, Bertilaccio MT, Antonini E, Neri A, et al. Rescue of Hippo coactivator YAP1 triggers DNA damage-induced apoptosis in hematological cancers. Nat Med. 2014;20(6):599-606.
-
(2014)
Nat Med
, vol.20
, Issue.6
, pp. 599-606
-
-
Cottini, F.1
Hideshima, T.2
Xu, C.3
Sattler, M.4
Dori, M.5
Agnelli, L.6
Hacken, E.7
Bertilaccio, M.T.8
Antonini, E.9
Neri, A.10
-
46
-
-
33947382284
-
The yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73
-
Levy D, Adamovich Y, Reuven N, Shaul Y. The yes-associated protein 1 stabilizes p73 by preventing Itch-mediated ubiquitination of p73. Cell Death Differ. 2007;14(4):743-51.
-
(2007)
Cell Death Differ
, vol.14
, Issue.4
, pp. 743-751
-
-
Levy, D.1
Adamovich, Y.2
Reuven, N.3
Shaul, Y.4
-
47
-
-
84890916735
-
Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase
-
Serrano I, McDonald PC, Lock F, Muller WJ, Dedhar S. Inactivation of the Hippo tumour suppressor pathway by integrin-linked kinase. Nat Commun. 2013;4:2976.
-
(2013)
Nat Commun
, vol.4
, pp. 2976
-
-
Serrano, I.1
McDonald, P.C.2
Lock, F.3
Muller, W.J.4
Dedhar, S.5
-
48
-
-
84871721147
-
Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila
-
Wehr MC, Holder MV, Gailite I, Saunders RE, Maile TM, Ciirdaeva E, Instrell R, Jiang M, Howell M, Rossner MJ, et al. Salt-inducible kinases regulate growth through the Hippo signalling pathway in Drosophila. Nat Cell Biol. 2013;15(1):61-71.
-
(2013)
Nat Cell Biol
, vol.15
, Issue.1
, pp. 61-71
-
-
Wehr, M.C.1
Holder, M.V.2
Gailite, I.3
Saunders, R.E.4
Maile, T.M.5
Ciirdaeva, E.6
Instrell, R.7
Jiang, M.8
Howell, M.9
Rossner, M.J.10
-
49
-
-
84865260845
-
Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling
-
Yu FX, Zhao B, Panupinthu N, Jewell JL, Lian I, Wang LH, Zhao J, Yuan H, Tumaneng K, Li H, et al. Regulation of the Hippo-YAP pathway by G-protein-coupled receptor signaling. Cell. 2012;150(4):780-91.
-
(2012)
Cell
, vol.150
, Issue.4
, pp. 780-791
-
-
Yu, F.X.1
Zhao, B.2
Panupinthu, N.3
Jewell, J.L.4
Lian, I.5
Wang, L.H.6
Zhao, J.7
Yuan, H.8
Tumaneng, K.9
Li, H.10
-
50
-
-
84922475217
-
G protein-coupled receptors: bridging the gap from the extracellular signals to the Hippo pathway
-
Zhou X, Wang Z, Huang W, Lei QY. G protein-coupled receptors: bridging the gap from the extracellular signals to the Hippo pathway. Acta Biochim Biophys Sin (Shanghai). 2015;47(1):10-5.
-
(2015)
Acta Biochim Biophys Sin (Shanghai)
, vol.47
, Issue.1
, pp. 10-15
-
-
Zhou, X.1
Wang, Z.2
Huang, W.3
Lei, Q.Y.4
-
51
-
-
84901048406
-
High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy
-
Rossi M, Rotblat B, Ansell K, Amelio I, Caraglia M, Misso G, Bernassola F, Cavasotto CN, Knight RA, Ciechanover A, et al. High throughput screening for inhibitors of the HECT ubiquitin E3 ligase ITCH identifies antidepressant drugs as regulators of autophagy. Cell Death Dis. 2014;5(5):e1203.
-
(2014)
Cell Death Dis
, vol.5
, Issue.5
-
-
Rossi, M.1
Rotblat, B.2
Ansell, K.3
Amelio, I.4
Caraglia, M.5
Misso, G.6
Bernassola, F.7
Cavasotto, C.N.8
Knight, R.A.9
Ciechanover, A.10
-
52
-
-
84912567137
-
Peptide and small molecule inhibitors of HECT-type ubiquitin ligases
-
Mund T, Lewis MJ, Maslen S, Pelham HR. Peptide and small molecule inhibitors of HECT-type ubiquitin ligases. Proc Natl Acad Sci USA. 2014;111(47):16736-41.
-
(2014)
Proc Natl Acad Sci USA
, vol.111
, Issue.47
, pp. 16736-16741
-
-
Mund, T.1
Lewis, M.J.2
Maslen, S.3
Pelham, H.R.4
-
53
-
-
84883150048
-
Structure-based design of covalent Siah inhibitors
-
Stebbins JL, Santelli E, Feng Y, De SK, Purves A, Motamedchaboki K, Wu B, Ronai ZA, Liddington RC, Pellecchia M. Structure-based design of covalent Siah inhibitors. Chem Biol. 2013;20(8):973-82.
-
(2013)
Chem Biol
, vol.20
, Issue.8
, pp. 973-982
-
-
Stebbins, J.L.1
Santelli, E.2
Feng, Y.3
De, S.K.4
Purves, A.5
Motamedchaboki, K.6
Wu, B.7
Ronai, Z.A.8
Liddington, R.C.9
Pellecchia, M.10
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