Fbxw7 is an independent prognostic marker and induces apoptosis and growth arrest by regulating YAP abundance in hepatocellular carcinoma

Molecular Cancer

Volumn 13, Issue 1, 2014, Pages

  Tu, Kangsheng ^a   Yang, Wei ^a   Li, Chao ^a   Zheng, Xin ^a   Lu, Zhongtang ^a   Guo, Cheng ^a   Yao, Yingmin ^a   Liu, Qingguang ^a  

^a THE FIRST AFFILIATED HOSPITAL OF XI AN JIAOTONG UNIVERSITY   (China)

Author keywords

Apoptosis; Fbxw7; Growth arrest; Hepatocellular carcinoma; Hippo YAP pathway

Indexed keywords

CELL CYCLE PROTEIN; F BOX PROTEIN; FBXW7 PROTEIN, HUMAN; PHOSPHOPROTEIN; PROTEASOME; SIGNAL TRANSDUCING ADAPTOR PROTEIN; TUMOR MARKER; UBIQUITIN PROTEIN LIGASE; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ADULT; AGED; ANIMAL; APOPTOSIS; CANCER GRADING; CANCER STAGING; CANCER TRANSPLANTATION; CARCINOMA, HEPATOCELLULAR; CELL CYCLE CHECKPOINT; CELL PROLIFERATION; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; LIVER NEOPLASMS; MALE; METABOLISM; MIDDLE AGED; MOUSE; NUDE MOUSE; PATHOLOGY; PROGNOSIS; PROTEIN DEGRADATION; SIGNAL TRANSDUCTION; TUMOR MICROENVIRONMENT;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ADULT; AGED; ANIMALS; APOPTOSIS; CARCINOMA, HEPATOCELLULAR; CELL CYCLE CHECKPOINTS; CELL CYCLE PROTEINS; CELL PROLIFERATION; F-BOX PROTEINS; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; LIVER NEOPLASMS; MALE; MICE; MICE, NUDE; MIDDLE AGED; NEOPLASM GRADING; NEOPLASM STAGING; NEOPLASM TRANSPLANTATION; PHOSPHOPROTEINS; PROGNOSIS; PROTEASOME ENDOPEPTIDASE COMPLEX; PROTEOLYSIS; SIGNAL TRANSDUCTION; TUMOR MARKERS, BIOLOGICAL; TUMOR MICROENVIRONMENT; UBIQUITIN-PROTEIN LIGASES;

EID: 84901437983     PISSN: None     EISSN: 14764598     Source Type: Journal    
DOI: 10.1186/1476-4598-13-110     Document Type: Article

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