Hypoxia regulates Hippo signalling through the SIAH2 ubiquitin E3 ligase

Nature Cell Biology

Volumn 17, Issue 1, 2015, Pages 95-103

  Ma, Biao ^a   Chen, Yan ^a   Chen, Ling ^a   Cheng, Hongcheng ^a   Mu, Chenglong ^a   Li, Jie ^a   Gao, Ruize ^a   Zhou, Changqian ^a   Cao, Lei ^a   Liu, Jinhua ^a   Zhu, Yushan ^a   Chen, Quan ^a,b   Wu, Shian ^a  

^a NANKAI UNIVERSITY   (China)

^b INSTITUTE OF ZOOLOGY   (China)

Author keywords

[No Author keywords available]

Indexed keywords

HYPOXIA INDUCIBLE FACTOR 1ALPHA; OXYGEN; PROTEIN KINASE; PROTEIN LATS2; PROTEIN SIAH2; UBIQUITIN PROTEIN LIGASE E3; UNCLASSIFIED DRUG; HIF1A PROTEIN, HUMAN; HIPPO PROTEIN, HUMAN; LATS2 PROTEIN, HUMAN; NUCLEAR PROTEIN; PHOSPHOPROTEIN; PROTEIN SERINE THREONINE KINASE; SEVEN IN ABSENTIA PROTEINS; SIGNAL TRANSDUCING ADAPTOR PROTEIN; SMALL INTERFERING RNA; TUMOR SUPPRESSOR PROTEIN; UBIQUITIN PROTEIN LIGASE; YAP1 (YES-ASSOCIATED) PROTEIN, HUMAN;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BREAST CANCER; BREAST CARCINOGENESIS; CANCER CELL CULTURE; CANCER TISSUE; CELL PROLIFERATION; CELL VIABILITY; CHROMATIN IMMUNOPRECIPITATION; CONTROLLED STUDY; DOWN REGULATION; FEMALE; FLOW CYTOMETRY; GENETIC TRANSFECTION; HIPPO SIGNALING; HUMAN; HUMAN CELL; HYPOXIA; IMMUNOBLOTTING; IMMUNOFLUORESCENCE MICROSCOPY; IMMUNOHISTOCHEMISTRY; IMMUNOPRECIPITATION; IN VITRO STUDY; IN VIVO STUDY; MASS SPECTROMETRY; MOLECULAR CLONING; MOLECULAR MECHANICS; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN STABILITY; REAL TIME POLYMERASE CHAIN REACTION; RNA ISOLATION; SIGNAL TRANSDUCTION; TUMOR XENOGRAFT; UBIQUITINATION; ANIMAL; BIOSYNTHESIS; BREAST TUMOR; CANCER TRANSPLANTATION; CELL HYPOXIA; CELL TRANSFORMATION; GENETICS; HEK293 CELL LINE; HELA CELL LINE; METABOLISM; NUDE MOUSE; PHOSPHORYLATION; PHYSIOLOGY; RNA INTERFERENCE; TUMOR CELL LINE; TUMOR MICROENVIRONMENT; XENOGRAFT;

ANIMALIA;

ADAPTOR PROTEINS, SIGNAL TRANSDUCING; ANIMALS; BREAST NEOPLASMS; CELL HYPOXIA; CELL LINE, TUMOR; CELL TRANSFORMATION, NEOPLASTIC; DOWN-REGULATION; FEMALE; HEK293 CELLS; HELA CELLS; HUMANS; HYPOXIA-INDUCIBLE FACTOR 1, ALPHA SUBUNIT; MICE; MICE, NUDE; NEOPLASM TRANSPLANTATION; NUCLEAR PROTEINS; PHOSPHOPROTEINS; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; RNA, SMALL INTERFERING; SIGNAL TRANSDUCTION; TRANSPLANTATION, HETEROLOGOUS; TUMOR MICROENVIRONMENT; TUMOR SUPPRESSOR PROTEINS; UBIQUITIN-PROTEIN LIGASES;

EID: 84926137241     PISSN: 14657392     EISSN: 14764679     Source Type: Journal    
DOI: 10.1038/ncb3073     Document Type: Article

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