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Volumn 8, Issue , 2010, Pages

Quantitative proteomic analysis by iTRAQ® for the identification of candidate biomarkers in ovarian cancer serum

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA 1 ANTICHYMOTRYPSIN; APOLIPOPROTEIN E; EXTRACELLULAR MATRIX PROTEIN 1; FIBRINOGEN; GALECTIN 3; GLYCOPROTEIN; HAPTOGLOBIN; INTER ALPHA GLOBULIN INHIBITOR H3; LEUCINE RICH ALPHA 2 GLYCOPROTEIN 2; LIPOPOLYSACCHARIDE BINDING PROTEIN; OROSOMUCOID 1; PROTEOGLYCAN 4; SCLEROPROTEIN; TUMOR MARKER; UNCLASSIFIED DRUG;

EID: 77953339286     PISSN: None     EISSN: 14775956     Source Type: Journal    
DOI: 10.1186/1477-5956-8-31     Document Type: Article
Times cited : (42)

References (49)
  • 5
    • 34548173778 scopus 로고    scopus 로고
    • Epithelial ovarian cancer: disease etiology, treatment, detection, and investigational gene, metabolite, and protein biomarkers
    • 10.1021/pr070041v, 17583933
    • Williams TI, Toups KL, Saggese DA, Kalli KR, Cliby WA, Muddiman DC. Epithelial ovarian cancer: disease etiology, treatment, detection, and investigational gene, metabolite, and protein biomarkers. J Proteome Res 2007, 6:2936-2962. 10.1021/pr070041v, 17583933.
    • (2007) J Proteome Res , vol.6 , pp. 2936-2962
    • Williams, T.I.1    Toups, K.L.2    Saggese, D.A.3    Kalli, K.R.4    Cliby, W.A.5    Muddiman, D.C.6
  • 6
    • 0032875697 scopus 로고    scopus 로고
    • Quantitative analysis of complex protein mixtures using isotope-coded affinity tags
    • 10.1038/13690, 10504701
    • Gygi SP, Rist B, Gerber SA, Turecek F, Gelb MH, Aebersold R. Quantitative analysis of complex protein mixtures using isotope-coded affinity tags. Nat Biotechnol 1999, 17:994-999. 10.1038/13690, 10504701.
    • (1999) Nat Biotechnol , vol.17 , pp. 994-999
    • Gygi, S.P.1    Rist, B.2    Gerber, S.A.3    Turecek, F.4    Gelb, M.H.5    Aebersold, R.6
  • 8
    • 33645463240 scopus 로고    scopus 로고
    • Proteins associated with Cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels
    • Stewart JJ, White JT, Yan X, Collins S, Drescher CW, Urban ND, Hood L, Lin B. Proteins associated with Cisplatin resistance in ovarian cancer cells identified by quantitative proteomic technology and integrated with mRNA expression levels. Mol Cell Proteomics 2006, 5:433-443.
    • (2006) Mol Cell Proteomics , vol.5 , pp. 433-443
    • Stewart, J.J.1    White, J.T.2    Yan, X.3    Collins, S.4    Drescher, C.W.5    Urban, N.D.6    Hood, L.7    Lin, B.8
  • 10
    • 77149146158 scopus 로고    scopus 로고
    • Identification of candidate biomarkers in ovarian cancer serum by depletion of highly abundant proteins and differential in-gel electrophoresis
    • 10.1002/elps.200900441, 20162585
    • Andersen JD, Boylan KLM, Xue FS, Anderson LB, Witthuhn BA, Markowski TW, Higgins L, Skubitz APN. Identification of candidate biomarkers in ovarian cancer serum by depletion of highly abundant proteins and differential in-gel electrophoresis. Electrophoresis 2010, 31. 10.1002/elps.200900441, 20162585.
    • (2010) Electrophoresis , vol.31
    • Andersen, J.D.1    Boylan, K.L.M.2    Xue, F.S.3    Anderson, L.B.4    Witthuhn, B.A.5    Markowski, T.W.6    Higgins, L.7    Skubitz, A.P.N.8
  • 11
    • 0028365934 scopus 로고
    • A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage
    • 10.1006/abbi.1994.1219, 8185311
    • Schumacher BL, Block JA, Schmid TM, Aydelotte MB, Kuettner KE. A novel proteoglycan synthesized and secreted by chondrocytes of the superficial zone of articular cartilage. Arch Biochem Biophys 1994, 311:144-152. 10.1006/abbi.1994.1219, 8185311.
    • (1994) Arch Biochem Biophys , vol.311 , pp. 144-152
    • Schumacher, B.L.1    Block, J.A.2    Schmid, T.M.3    Aydelotte, M.B.4    Kuettner, K.E.5
  • 12
    • 35648936933 scopus 로고    scopus 로고
    • Differential protein expression in male and female human lumbar cerebrospinal fluid using iTRAQ reagents after abundant protein depletion
    • 10.1002/pmic.200700455, 17853512
    • Ogata Y, Charlesworth MC, Higgins L, Keegan BM, Vernino S, Muddiman DC. Differential protein expression in male and female human lumbar cerebrospinal fluid using iTRAQ reagents after abundant protein depletion. Proteomics 2007, 7:3726-3734. 10.1002/pmic.200700455, 17853512.
    • (2007) Proteomics , vol.7 , pp. 3726-3734
    • Ogata, Y.1    Charlesworth, M.C.2    Higgins, L.3    Keegan, B.M.4    Vernino, S.5    Muddiman, D.C.6
  • 13
    • 70350099073 scopus 로고    scopus 로고
    • Deep depletion of abundant serum proteins reveals low-abundant proteins as potential biomarkers for human ovarian cancer
    • Lin B, White JT, Wu J, Lele S, Old LJ, Hood L, Odunsi K. Deep depletion of abundant serum proteins reveals low-abundant proteins as potential biomarkers for human ovarian cancer. Proteomics Clin Appl 2009, 3:853-861.
    • (2009) Proteomics Clin Appl , vol.3 , pp. 853-861
    • Lin, B.1    White, J.T.2    Wu, J.3    Lele, S.4    Old, L.J.5    Hood, L.6    Odunsi, K.7
  • 14
    • 38949159130 scopus 로고    scopus 로고
    • Breast cancer related proteins are present in saliva and are modulated secondary to ductal carcinoma in situ of the breast
    • 10.1080/07357900701783883, 18259946
    • Streckfus CF, Mayorga-Wark O, Arreola D, Edwards C, Bigler L, Dubinsky WP. Breast cancer related proteins are present in saliva and are modulated secondary to ductal carcinoma in situ of the breast. Cancer Invest 2008, 26:159-167. 10.1080/07357900701783883, 18259946.
    • (2008) Cancer Invest , vol.26 , pp. 159-167
    • Streckfus, C.F.1    Mayorga-Wark, O.2    Arreola, D.3    Edwards, C.4    Bigler, L.5    Dubinsky, W.P.6
  • 15
    • 28444458895 scopus 로고    scopus 로고
    • Proteomic tracking of serum protein isoforms as screening biomarkers of ovarian cancer
    • 10.1002/pmic.200401321, 16220531
    • Ahmed N, Oliva KT, Barker G, Hoffmann P, Reeve S, Smith IA, Quinn MA, Rice GE. Proteomic tracking of serum protein isoforms as screening biomarkers of ovarian cancer. Proteomics 2005, 5:4625-4636. 10.1002/pmic.200401321, 16220531.
    • (2005) Proteomics , vol.5 , pp. 4625-4636
    • Ahmed, N.1    Oliva, K.T.2    Barker, G.3    Hoffmann, P.4    Reeve, S.5    Smith, I.A.6    Quinn, M.A.7    Rice, G.E.8
  • 16
    • 0015128225 scopus 로고
    • Serum haptoglobin in patients with ovarian malignancies
    • Mueller WK, Handschumacher R, Wade ME. Serum haptoglobin in patients with ovarian malignancies. Obstet Gynecol 1971, 38:427-435.
    • (1971) Obstet Gynecol , vol.38 , pp. 427-435
    • Mueller, W.K.1    Handschumacher, R.2    Wade, M.E.3
  • 18
    • 33846818675 scopus 로고    scopus 로고
    • Circulating haptoglobin is an independent prognostic factor in the sera of patients with epithelial ovarian cancer
    • 10.1593/neo.06619, 1803031, 17325738
    • Zhao C, Annamalai L, Guo C, Kothandaraman N, Koh SC, Zhang H, Biswas A, Choolani M. Circulating haptoglobin is an independent prognostic factor in the sera of patients with epithelial ovarian cancer. Neoplasia 2007, 9:1-7. 10.1593/neo.06619, 1803031, 17325738.
    • (2007) Neoplasia , vol.9 , pp. 1-7
    • Zhao, C.1    Annamalai, L.2    Guo, C.3    Kothandaraman, N.4    Koh, S.C.5    Zhang, H.6    Biswas, A.7    Choolani, M.8
  • 19
    • 3342986675 scopus 로고    scopus 로고
    • Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer
    • 10.1038/sj.bjc.6601882, 2364749, 15199385
    • Ahmed N, Barker G, Oliva KT, Hoffmann P, Riley C, Reeve S, Smith AI, Kemp BE, Quinn MA, Rice GE. Proteomic-based identification of haptoglobin-1 precursor as a novel circulating biomarker of ovarian cancer. Br J Cancer 2004, 91:129-140. 10.1038/sj.bjc.6601882, 2364749, 15199385.
    • (2004) Br J Cancer , vol.91 , pp. 129-140
    • Ahmed, N.1    Barker, G.2    Oliva, K.T.3    Hoffmann, P.4    Riley, C.5    Reeve, S.6    Smith, A.I.7    Kemp, B.E.8    Quinn, M.A.9    Rice, G.E.10
  • 23
    • 61849133375 scopus 로고    scopus 로고
    • Absolute quantification of C-reactive protein in human plasma derived from patients with epithelial ovarian cancer utilizing protein cleavage isotope dilution mass spectrometry
    • 10.1021/pr800922p, 2637469, 19196186
    • Williams DK, Muddiman DC. Absolute quantification of C-reactive protein in human plasma derived from patients with epithelial ovarian cancer utilizing protein cleavage isotope dilution mass spectrometry. J Proteome Res 2009, 8:1085-1090. 10.1021/pr800922p, 2637469, 19196186.
    • (2009) J Proteome Res , vol.8 , pp. 1085-1090
    • Williams, D.K.1    Muddiman, D.C.2
  • 26
    • 0029917914 scopus 로고    scopus 로고
    • Two-dimensional electrophoretic patterns of acute-phase human serum proteins in the course of bacterial and viral diseases
    • 10.1002/elps.1150170333, 8740187
    • Bini L, Magi B, Marzocchi B, Cellesi C, Berti B, Raggiaschi R, Rossolini A, Pallini V. Two-dimensional electrophoretic patterns of acute-phase human serum proteins in the course of bacterial and viral diseases. Electrophoresis 1996, 17:612-616. 10.1002/elps.1150170333, 8740187.
    • (1996) Electrophoresis , vol.17 , pp. 612-616
    • Bini, L.1    Magi, B.2    Marzocchi, B.3    Cellesi, C.4    Berti, B.5    Raggiaschi, R.6    Rossolini, A.7    Pallini, V.8
  • 28
    • 26844512938 scopus 로고    scopus 로고
    • Characterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometry
    • 10.1021/pr050174l, 16212428
    • Yu KH, Rustgi AK, Blair IA. Characterization of proteins in human pancreatic cancer serum using differential gel electrophoresis and tandem mass spectrometry. J Proteome Res 2005, 4:1742-1751. 10.1021/pr050174l, 16212428.
    • (2005) J Proteome Res , vol.4 , pp. 1742-1751
    • Yu, K.H.1    Rustgi, A.K.2    Blair, I.A.3
  • 29
    • 34249688237 scopus 로고    scopus 로고
    • Plasma proteomics of pancreatic cancer patients by multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis (2D-DIGE): up-regulation of leucine-rich alpha-2-glycoprotein in pancreatic cancer
    • 10.1016/j.jchromb.2007.01.029, 17303479
    • Kakisaka T, Kondo T, Okano T, Fujii K, Honda K, Endo M, Tsuchida A, Aoki T, Itoi T, Moriyasu F, Yamada T, Kato H, Nishimura T, Todo S, Hirohashi S. Plasma proteomics of pancreatic cancer patients by multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis (2D-DIGE): up-regulation of leucine-rich alpha-2-glycoprotein in pancreatic cancer. J Chromatogr B Analyt Technol Biomed Life Sci 2007, 852:257-267. 10.1016/j.jchromb.2007.01.029, 17303479.
    • (2007) J Chromatogr B Analyt Technol Biomed Life Sci , vol.852 , pp. 257-267
    • Kakisaka, T.1    Kondo, T.2    Okano, T.3    Fujii, K.4    Honda, K.5    Endo, M.6    Tsuchida, A.7    Aoki, T.8    Itoi, T.9    Moriyasu, F.10    Yamada, T.11    Kato, H.12    Nishimura, T.13    Todo, S.14    Hirohashi, S.15
  • 30
    • 33745994676 scopus 로고    scopus 로고
    • Plasma proteomics of lung cancer by a linkage of multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis
    • 10.1002/pmic.200500883, 16767791
    • Okano T, Kondo T, Kakisaka T, Fujii K, Yamada M, Kato H, Nishimura T, Gemma A, Kudoh S, Hirohashi S. Plasma proteomics of lung cancer by a linkage of multi-dimensional liquid chromatography and two-dimensional difference gel electrophoresis. Proteomics 2006, 6:3938-3948. 10.1002/pmic.200500883, 16767791.
    • (2006) Proteomics , vol.6 , pp. 3938-3948
    • Okano, T.1    Kondo, T.2    Kakisaka, T.3    Fujii, K.4    Yamada, M.5    Kato, H.6    Nishimura, T.7    Gemma, A.8    Kudoh, S.9    Hirohashi, S.10
  • 34
    • 69249100942 scopus 로고    scopus 로고
    • Quantitative proteomics analysis integrated with microarray data reveals that extracellular matrix proteins, catenins, and p53 binding protein 1 are important for chemotherapy response in ovarian cancers
    • 10.1089/omi.2009.0008, 19422301
    • Pan S, Cheng L, White JT, Lu W, Utleg AG, Yan X, Urban ND, Drescher CW, Hood L, Lin B. Quantitative proteomics analysis integrated with microarray data reveals that extracellular matrix proteins, catenins, and p53 binding protein 1 are important for chemotherapy response in ovarian cancers. Omics 2009, 13:345-354. 10.1089/omi.2009.0008, 19422301.
    • (2009) Omics , vol.13 , pp. 345-354
    • Pan, S.1    Cheng, L.2    White, J.T.3    Lu, W.4    Utleg, A.G.5    Yan, X.6    Urban, N.D.7    Drescher, C.W.8    Hood, L.9    Lin, B.10
  • 35
    • 1642469279 scopus 로고    scopus 로고
    • Hemangiopoietin, a novel human growth factor for the primitive cells of both hematopoietic and endothelial cell lineages
    • 10.1182/blood-2003-06-1825, 14976050
    • Liu YJ, Lu SH, Xu B, Yang RC, Ren Q, Liu B, Li B, Lu M, Yan FY, Han ZB, Han ZC. Hemangiopoietin, a novel human growth factor for the primitive cells of both hematopoietic and endothelial cell lineages. Blood 2004, 103:4449-4456. 10.1182/blood-2003-06-1825, 14976050.
    • (2004) Blood , vol.103 , pp. 4449-4456
    • Liu, Y.J.1    Lu, S.H.2    Xu, B.3    Yang, R.C.4    Ren, Q.5    Liu, B.6    Li, B.7    Lu, M.8    Yan, F.Y.9    Han, Z.B.10    Han, Z.C.11
  • 36
    • 0033608160 scopus 로고    scopus 로고
    • Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and Is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism
    • 10.1006/bbrc.1998.0104, 9920774
    • Flannery CR, Hughes CE, Schumacher BL, Tudor D, Aydelotte MB, Kuettner KE, Caterson B. Articular cartilage superficial zone protein (SZP) is homologous to megakaryocyte stimulating factor precursor and Is a multifunctional proteoglycan with potential growth-promoting, cytoprotective, and lubricating properties in cartilage metabolism. Biochem Biophys Res Commun 1999, 254:535-541. 10.1006/bbrc.1998.0104, 9920774.
    • (1999) Biochem Biophys Res Commun , vol.254 , pp. 535-541
    • Flannery, C.R.1    Hughes, C.E.2    Schumacher, B.L.3    Tudor, D.4    Aydelotte, M.B.5    Kuettner, K.E.6    Caterson, B.7
  • 37
    • 0034528946 scopus 로고    scopus 로고
    • Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes
    • 10.1159/000056791, 11124536
    • Ikegawa S, Sano M, Koshizuka Y, Nakamura Y. Isolation, characterization and mapping of the mouse and human PRG4 (proteoglycan 4) genes. Cytogenet Cell Genet 2000, 90:291-297. 10.1159/000056791, 11124536.
    • (2000) Cytogenet Cell Genet , vol.90 , pp. 291-297
    • Ikegawa, S.1    Sano, M.2    Koshizuka, Y.3    Nakamura, Y.4
  • 38
    • 0029522992 scopus 로고
    • Lipopolysaccharide binding protein participation in cellular activation by LPS
    • Su GL, Simmons RL, Wang SC. Lipopolysaccharide binding protein participation in cellular activation by LPS. Crit Rev Immunol 1995, 15:201-214.
    • (1995) Crit Rev Immunol , vol.15 , pp. 201-214
    • Su, G.L.1    Simmons, R.L.2    Wang, S.C.3
  • 39
    • 44449152171 scopus 로고    scopus 로고
    • ITRAQ-facilitated proteomic analysis of human prostate cancer cells identifies proteins associated with progression
    • 10.1021/pr070378x, 18232632
    • Glen A, Gan CS, Hamdy FC, Eaton CL, Cross SS, Catto JW, Wright PC, Rehman I. iTRAQ-facilitated proteomic analysis of human prostate cancer cells identifies proteins associated with progression. J Proteome Res 2008, 7:897-907. 10.1021/pr070378x, 18232632.
    • (2008) J Proteome Res , vol.7 , pp. 897-907
    • Glen, A.1    Gan, C.S.2    Hamdy, F.C.3    Eaton, C.L.4    Cross, S.S.5    Catto, J.W.6    Wright, P.C.7    Rehman, I.8
  • 40
    • 17444383113 scopus 로고    scopus 로고
    • Search for cancer markers from endometrial tissues using differentially labeled tags iTRAQ and cICAT with multidimensional liquid chromatography and tandem mass spectrometry
    • 10.1021/pr049821j, 15822913
    • DeSouza L, Diehl G, Rodrigues MJ, Guo J, Romaschin AD, Colgan TJ, Siu KW. Search for cancer markers from endometrial tissues using differentially labeled tags iTRAQ and cICAT with multidimensional liquid chromatography and tandem mass spectrometry. J Proteome Res 2005, 4:377-386. 10.1021/pr049821j, 15822913.
    • (2005) J Proteome Res , vol.4 , pp. 377-386
    • DeSouza, L.1    Diehl, G.2    Rodrigues, M.J.3    Guo, J.4    Romaschin, A.D.5    Colgan, T.J.6    Siu, K.W.7
  • 41
    • 34547131803 scopus 로고    scopus 로고
    • Endometrial carcinoma biomarker discovery and verification using differentially tagged clinical samples with multidimensional liquid chromatography and tandem mass spectrometry
    • 10.1074/mcp.M600378-MCP200, 17374602
    • DeSouza LV, Grigull J, Ghanny S, Dube V, Romaschin AD, Colgan TJ, Siu KW. Endometrial carcinoma biomarker discovery and verification using differentially tagged clinical samples with multidimensional liquid chromatography and tandem mass spectrometry. Mol Cell Proteomics 2007, 6:1170-1182. 10.1074/mcp.M600378-MCP200, 17374602.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 1170-1182
    • DeSouza, L.V.1    Grigull, J.2    Ghanny, S.3    Dube, V.4    Romaschin, A.D.5    Colgan, T.J.6    Siu, K.W.7
  • 42
    • 46749120270 scopus 로고    scopus 로고
    • Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ-labeling and multidimensional liquid chromatography and tandem mass spectrometry
    • 2424195, 18339795
    • Ralhan R, Desouza LV, Matta A, Chandra Tripathi S, Ghanny S, Datta Gupta S, Bahadur S, Siu KW. Discovery and verification of head-and-neck cancer biomarkers by differential protein expression analysis using iTRAQ-labeling and multidimensional liquid chromatography and tandem mass spectrometry. Mol Cell Proteomics 2008, 2424195, 18339795.
    • (2008) Mol Cell Proteomics
    • Ralhan, R.1    Desouza, L.V.2    Matta, A.3    Chandra Tripathi, S.4    Ghanny, S.5    Datta Gupta, S.6    Bahadur, S.7    Siu, K.W.8
  • 45
    • 54249154831 scopus 로고    scopus 로고
    • Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer
    • 10.1158/1055-9965.EPI-08-0464, 18843033
    • Bertenshaw GP, Yip P, Seshaiah P, Zhao J, Chen TH, Wiggins WS, Mapes JP, Mansfield BC. Multianalyte profiling of serum antigens and autoimmune and infectious disease molecules to identify biomarkers dysregulated in epithelial ovarian cancer. Cancer Epidemiol Biomarkers Prev 2008, 17:2872-2881. 10.1158/1055-9965.EPI-08-0464, 18843033.
    • (2008) Cancer Epidemiol Biomarkers Prev , vol.17 , pp. 2872-2881
    • Bertenshaw, G.P.1    Yip, P.2    Seshaiah, P.3    Zhao, J.4    Chen, T.H.5    Wiggins, W.S.6    Mapes, J.P.7    Mansfield, B.C.8
  • 47
    • 34447133483 scopus 로고    scopus 로고
    • Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels
    • 10.1158/0008-5472.CAN-06-4438, 17616712
    • Kassie F, Anderson LB, Scherber R, Yu N, Lahti D, Upadhyaya P, Hecht SS. Indole-3-carbinol inhibits 4-(methylnitrosamino)-1-(3-pyridyl)-1-butanone plus benzo(a)pyrene-induced lung tumorigenesis in A/J mice and modulates carcinogen-induced alterations in protein levels. Cancer Res 2007, 67:6502-6511. 10.1158/0008-5472.CAN-06-4438, 17616712.
    • (2007) Cancer Res , vol.67 , pp. 6502-6511
    • Kassie, F.1    Anderson, L.B.2    Scherber, R.3    Yu, N.4    Lahti, D.5    Upadhyaya, P.6    Hecht, S.S.7
  • 48
    • 34848889259 scopus 로고    scopus 로고
    • The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra
    • 10.1074/mcp.T600050-MCP200, 17533153
    • Shilov IV, Seymour SL, Patel AA, Loboda A, Tang WH, Keating SP, Hunter CL, Nuwaysir LM, Schaeffer DA. The Paragon Algorithm, a next generation search engine that uses sequence temperature values and feature probabilities to identify peptides from tandem mass spectra. Mol Cell Proteomics 2007, 6:1638-1655. 10.1074/mcp.T600050-MCP200, 17533153.
    • (2007) Mol Cell Proteomics , vol.6 , pp. 1638-1655
    • Shilov, I.V.1    Seymour, S.L.2    Patel, A.A.3    Loboda, A.4    Tang, W.H.5    Keating, S.P.6    Hunter, C.L.7    Nuwaysir, L.M.8    Schaeffer, D.A.9
  • 49
    • 33847630405 scopus 로고    scopus 로고
    • Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry
    • 10.1038/nmeth1019, 17327847
    • Elias JE, Gygi SP. Target-decoy search strategy for increased confidence in large-scale protein identifications by mass spectrometry. Nat Methods 2007, 4:207-214. 10.1038/nmeth1019, 17327847.
    • (2007) Nat Methods , vol.4 , pp. 207-214
    • Elias, J.E.1    Gygi, S.P.2


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