Coaggregation of RNA-binding proteins in a model of TDP-43 proteinopathy with selective RGG motif methylation and a role for RRM1 ubiquitination

PLoS ONE

Volumn 7, Issue 6, 2012, Pages

  Dammer, Eric B ^a   Fallini, Claudia ^a   Gozal, Yair M ^a   Duong, Duc M ^a   Rossoll, Wilfried ^a   Xu, Ping ^a,b   Lah, James J ^a   Levey, Allan I ^a   Peng, Junmin ^a,c   Bassell, Gary J ^a   Seyfried, Nicholas T ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b BEIJING INSTITUTE OF RADIATION MEDICINE   (China)

^c ST JUDE CHILDREN S RESEARCH HOSPITAL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ARGININE; FUSED IN SARCOMA PROTEIN; GLYCINE; HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN; INITIATION FACTOR 4A; PROTEIN ELF4A1; PROTEIN G3BP; PROTEIN NONO; PROTEIN PABPC1; PROTEIN PSF; PROTEIN RBM14; PROTEIN RRM1; PROTEIN TDP S6; PROTEIN VARIANT; PROTEOME; RNA BINDING MOTIF 1; RNA BINDING PROTEIN; TAR DNA BINDING PROTEIN; UBIQUITIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CELL FRACTIONATION; CELL GRANULE; CELL STRAIN HEK293; CELL STRESS; CONTROLLED STUDY; DISEASE MODEL; EMBRYO; FEMALE; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; ISOTOPE LABELING; LIQUID CHROMATOGRAPHY; MOTONEURON; MOUSE; MUTAGENESIS; NONHUMAN; NUCLEOTIDE SEQUENCE; OLIGOMERIZATION; OXIDATIVE STRESS; PROTEIN AGGREGATION; PROTEIN ANALYSIS; PROTEIN FUNCTION; PROTEIN METHYLATION; PROTEIN MOTIF; PROTEIN PROCESSING; PROTEIN PROTEIN INTERACTION; PROTEOMICS; TANDEM MASS SPECTROMETRY; TDP 43 PROTEINOPATHY; UBIQUITINATION; WESTERN BLOTTING;

AMINO ACID MOTIFS; ANIMALS; ARGININE; BLOTTING, WESTERN; CELL NUCLEUS; CYTOPLASM; DNA-BINDING PROTEINS; GLYCINE; HEK293 CELLS; HUMANS; METHYLATION; MICE; MICE, INBRED C57BL; MOTOR NEURONS; PEPTIDE FRAGMENTS; PROTEIN MULTIMERIZATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; PROTEOMICS; REAL-TIME POLYMERASE CHAIN REACTION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA-BINDING PROTEINS; TANDEM MASS SPECTROMETRY; TDP-43 PROTEINOPATHIES; TUMOR SUPPRESSOR PROTEINS; UBIQUITINATION;

EID: 84862667481     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0038658     Document Type: Article

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