Attention deficit hyperactivity disorder: Insight from quantitative genetic research

Behavior Genetics of Psychopathology

Volumn , Issue , 2014, Pages 1-32

  Frazier Wood, Alexis C ^a   Rommel, Anna S ^b   Kuntsi, Jonna ^b  

^a UNIVERSITY OF TEXAS SCHOOL OF PUBLIC HEALTH   (United States)

^b MEDICAL RESEARCH COUNCIL   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

EID: 84977078700     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1007/978-1-4614-9509-3_1     Document Type: Chapter

References (151)

1. Abikoff, H., Courtney, M., Pelham, W. E., & Koplewicz, H. S. (1993). Teachers' Ratings of disruptive behaviors: The influence of halo effects. Journal of Abnormal Child Psychology, 21 (5), 519-533.
2. Abramowitz, C., Kosson, D., & Seidenberg, M. (2004). The relationship between childhood attention deficit hyperactivity disorder and conduct problems and adult psychopathy in male inmates. Personality and Individual Differences, 36 (5), 1031-1047.
3. Albrecht, B., Brandeis, D., Uebel, H., Heinrich, H., Heise, A., Hasselhorn, M., et al. (2010). Action monitoring in children with or without a family history of ADHD-effects of gender on an endophenotype parameter. Neuropsychologia, 48 (4), 1171-1177.
4. Albrecht, B., Brandeis, D., Uebel, H., Heinrich, H., Mueller, U. C., Hasselhorn, M., et al. (2008). Action monitoring in boys with attention-deficit/hyperactivity disorder, their nonaffected siblings, and normal control subjects: Evidence for an endophenotype. Biological Psychiatry, 64 (7), 615-625.
5. American Psychiatric Association. (1968). Diagnostic and statistical manual of mental disorders- Second edition (DSM-II). Washington, DC: American Psychiatric Association.
6. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders- Fourth edition (DSM-IV). Washington, DC: American Psychiatric Association.
7. American Psychiatric Association. (2000). Diagnostic and statistical manual of mental disorders. Washington, DC: American Psychiatric Association.
8. American Psychiatric Association. (2012). Proposed revision-attention deficit/hyperactivity disorder, DSM-5 development. Washington, DC: Author.
9. Andreou, P., Neale, B. M., Chen, W., Christiansen, H., Gabriels, I., Heise, A., et al. (2007). Reaction time performance in ADHD: Improvement under fast-incentive condition and familial effects. Psychological Medicine, 37 (12), 1703-1715.
10. Asherson, P., & Gurling, H. (2012). Quantitative and molecular genetics of ADHD. Current Topics in Behavioral Neurosciences, 9, 239-272.
11. August, G. J., & Garfinkel, B. D. (1990). Comorbidity of ADHD and reading disability among clinic-referred children. Journal of Abnormal Child Psychology, 18 (1), 29-45.
12. Banaschewski, T., & Brandeis, D. (2007). Annotation: What electrical brain activity tells us about brain function that other techniques cannot tell us-a child psychiatric perspective. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 48 (5), 415-435.
13. Barcons-Castel, N., Fornieles-Deu, A., & Costas-Moragas, C. (2011). International adoption: Assessment of adaptive and maladaptive behavior of adopted minors in Spain. The Spanish Journal of Psychology, 14 (1), 123-132.
14. Barkley, R. A. (2008). Global issues related to the impact of untreated attention-deficit/hyperactivity disorder from childhood to young adulthood. Postgraduate Medicine, 120 (3), 48-59.
15. Bidwell, L. C., Willcutt, E. G., Defries, J. C., & Pennington, B. F. (2007). Testing for neuropsychological endophenotypes in siblings discordant for attention-deficit/hyperactivity disorder. Biological Psychiatry, 62 (9), 991-998.
16. Bitter, I., Simon, V., Bálint, S., Mészáros, A., & Czobor, P. (2010). How do different diagnostic criteria, age and gender affect the prevalence of attention deficit hyperactivity disorder in adults? An epidemiological study in a Hungarian community sample. European Archives of Psychiatry and Clinical Neuroscience, 260 (4), 287-296.
17. Burt, S. A. (2009). Rethinking environmental contributions to child and adolescent psychopathology: A meta-analysis of shared environmental influences. Psychological Bulletin, 135, 608-637.
18. Burt, S. A. (2010). Are there shared environmental influences on attention-deficit/hyperactivity disorder? Reply to Wood, Buitelaar, Rijsdijk, Asherson, and Kuntsi [corrected] (2010). Psychological Bulletin, 136 (3), 341-343.
19. Burt, S. A., Krueger, R. F., McGue, M., & Iacono, W. G. (2001). Sources of covariation among attention- deficit/hyperactivity disorder, oppositional defiant disorder, and conduct disorder: The importance of shared environment. Journal of Abnormal Psychology, 110 (4), 516-525.
20. Carr, L., Henderson, J., & Nigg, J. T. (2010). Cognitive control and attentional selection in adolescents with ADHD versus ADD. Journal of Clinical Child and Adolescent Psychology, 39 (6), 726-740.
21. Chen, W., & Taylor, E. (2006). Parental account of children's symptoms (PACS), ADHD phenotypes and its application to molecular genetic studies. In R. D. Oades (Ed.), Attention-deficit/ hyperactivity disorder (AD/HD) and the hyperkinetic syndrome (HKS): Current ideas and ways forward (pp. 3-20). Hauppauge, NY: Nova Science.
22. Chen, W., Zhou, K., Sham, P., Franke, B., Kuntsi, J., Campbell, D., et al. (2008). DSM-IV combined type ADHD shows familial association with sibling trait scores: A sampling strategy for QTL linkage. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 147B (8), 1450-1460.
23. Cheung, C. H. M., Wood, A. C., Paloyelis, Y., Arias-Vasquez, A., Buitelaar, J. K., Franke, B., et al. (2012). The aetiology for the covariation between combined type ADHD and reading difficulties in a family study: The role of IQ. Journal of Child Psychology and Psychiatry, 53, 864-873.
24. Choudhry, Z., Sengupta, S. M., Grizenko, N., Fortier, M.-E., Thakur, G. A., Bellingham, J., et al. (2012). LPHN3 and attention-deficit/hyperactivity disorder: Interaction with maternal stress during pregnancy. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 53 (8), 892-902.
25. Clark, T., Feehan, C., Tinline, C., & Vostanis, P. (1999). Autistic symptoms in children with attention deficit-hyperactivity disorder. European Child & Adolescent Psychiatry, 8 (1), 50-55. doi: 10.1007/s007870050083.
26. Constantino, J. N., Gruber, C. P., Davis, S., Hayes, S., Passanante, N., & Przybeck, T. (2004). The factor structure of autistic traits. Journal of Child Psychology and Psychiatry, 45 (4), 719-726.
27. Cook, E. H., Stein, M. A., Krasowski, M. D., Cox, N. J., Olkon, D. M., Kieffer, J. E., et al. (1995). Association of attention-deficit disorder and the dopamine transporter gene. American Journal of Human Genetics, 56 (4), 993-998.
28. Cosgrove, V. E., Rhee, S. H., Gelhorn, H. L., Boeldt, D., Corley, R. C., Ehringer, M. A., et al. (2011). Structure and etiology of co-occurring internalizing and externalizing disorders in adolescents. Journal of Abnormal Child Psychology, 39 (1), 109-123.
29. de Zwaan, M., Gruss, B., Müller, A., Graap, H., Martin, A., Glaesmer, H., et al. (2012). The estimated prevalence and correlates of adult ADHD in a German community sample. European Archives of Psychiatry and Clinical Neuroscience, 262 (1), 79-86.
30. Derks, E. M., Dolan, C., Hudziak, J., Neale, M. C., & Boomsma, D. (2007). Assessment and etiology of attention deficit hyperactivity disorder and oppositional defiant disorder in boys and girls. Behavior Genetics, 37 (4), 559-566.
31. Deutsch, C. K., Swanson, J. M., Bruell, J. H., Cantwell, D. P., Weinberg, F., & Baren, M. (1982). Overrepresentation of adoptees in children with the attention deficit disorder. Behavior Genetics, 12 (2), 231-238.
32. Doyle A. E., Willcutt E. G., Seidman L. J., Biederman J., Chouinard V. A., Silva J., Faraone S. V. (2005). Attention-deficit/hyperactivity disorder endophenotypes. Biol Psychiatry. 57, 1324-1335.
33. Durston, S. (2010). Imaging genetics in ADHD. Neuroimage, 53(3), 832-838.
34. Durston, S., Hulshoff Pol, H. E., Schnack, H. G., Buitelaar, J. K., Steenhuis, M. P., Minderaa, R. B., et al. (2004). Magnetic resonance imaging of boys with attention-deficit/hyperactivity disorder and their unaffected siblings. Journal of the American Academy of Child & Adolescent Psychiatry, 43 (3), 332-340.
35. Durston, S., Mulder, M., Casey, B. J., Ziermans, T., & Van Engeland, H. (2006). Activation in ventral prefrontal cortex is sensitive to genetic vulnerability for attention-deficit hyperactivity disorder. Biological Psychiatry, 60 (10), 1062-1070.
36. Dykman, R. A., & Ackerman, P. T. (1991). Attention deficit disorder and specific reading disability: Separate but often overlapping disorders. Journal of Learning Disabilities, 24, 96-103.
37. Ebejer, J. L., Coventry, W. L., Byrne, B., Willcutt, E. G., Olson, R. K., Corley, R., et al. (2010). Genetic and environmental influences on inattention, hyperactivity-impulsivity, and reading: Kindergarten to grade 2. Scientific Studies of Reading, 14 (4), 293-316.
38. Epstein, J. N., Conners, C. K., Erhardt, D., Arnold, L. E., Hechtman, L., Hinshaw, S. P., et al. (2000). Familial aggregation of ADHD characteristics. Journal of Abnormal Child Psychology, 28 (6), 585-594.
39. Faraone, S. V., Biederman, J., & Friedman, D. (2000). Validity of DSM-IV subtypes of attentiondeficit/hyperactivity disorder: A family study perspective. Journal of the American Academy of Child and Adolescent Psychiatry, 39 (3), 300-307.
40. Faraone, S. V., Biederman, J., Mick, E., Doyle, A. E., Wilens, T., Spencer, T., et al. (2001). A family study of psychiatric comorbidity in girls and boys with attention-deficit/hyperactivity disorder. Biological Psychiatry, 50 (8), 586-592.
41. Faraone, S. V., Biederman, J., & Milberger, S. (1994). An exploratory study of ADHD among second-degree relatives of ADHD children. Biological Psychiatry, 35 (6), 398-402.
42. Faraone, S. V., Perlis, R. H., Doyle, A. E., Smoller, J. W., Goralnick, J. J., Holmgren, M. A., et al. (2005). Molecular genetics of attention-deficit/hyperactivity disorder. Biological Psychiatry, 57 (11), 1313-1323.
43. Faraone, S. V., Sergeant, J., Gillberg, C., & Biederman, J. (2003). The worldwide prevalence of ADHD: Is it an American condition? World Psychiatry, 2 (2), 104-113.
44. Fergusson, D. M., & Horwood, L. J. (1995). Predictive validity of categorically and dimensionally scored measures of disruptive childhood behaviors. Journal of the American Academy of Child and Adolescent Psychiatry, 34 (4), 477-485.
45. Franke, B., Neale, B. M., & Faraone, S. V. (2009). Genome-wide association studies in ADHD. Human Genetics, 126 (1), 13-50.
46. Gau, S. S.-F., & Shang, C.-Y. (2010). Executive functions as endophenotypes in ADHD: Evidence from the Cambridge Neuropsychological Test Battery (CANTAB). The Journal of Child Psychology and Psychiatry and Allied Disciplines, 51 (7), 838-849.
47. Ghanizadeh, A. (2012). Psychometric analysis of the new ADHD DSM-V derived symptoms. BMC Psychiatry, 12, 21.
48. Gizer, I. R., Ficks, C., & Waldman, I. D. (2009). Candidate gene studies of ADHD: A metaanalytic review. Human Genetics, 126 (1), 51-90.
49. Goldstein, S., & Schwebach, A. J. (2004). The comorbidity of pervasive developmental disorder and attention deficit hyperactivity disorder: Results of a retrospective chart review. Journal of Autism and Developmental Disorders, 34 (3), 329-339.
50. Goos, L. M., Crosbie, J., Payne, S., & Schachar, R. (2009). Validation and extension of the endophenotype model in ADHD patterns of inheritance in a family study of inhibitory control. The American Journal of Psychiatry, 166 (6), 711-717.
51. Gottesman, I. I., & Gould, T. D. (2003). The endophenotype concept in psychiatry: Etymology and strategic intentions. The American Journal of Psychiatry, 160 (4), 636-645.
52. Greven, C. U., Asherson, P., Rijsdijk, F. V., & Plomin, R. (2011). A longitudinal twin study on the association between inattentive and hyperactive-impulsive ADHD symptoms. Journal of Abnormal Child Psychology, 39 (5), 623-632.
53. Greven, C. U., Harlaar, N., Dale, P. S., & Plomin, R. (2011). Genetic overlap between ADHD symptoms and reading is largely driven by inattentiveness rather than hyperactivity- impulsivity. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 20 (1), 6-14.
54. Grizenko, N., Fortier, M.-E., Zadorozny, C., Thakur, G., Schmitz, N., Duval, R., et al. (2012). Maternal stress during pregnancy, ADHD symptomatology in children and genotype: Geneenvironment interaction. Journal of the Canadian Academy of Child and Adolescent Psychiatry, 21 (1), 9-15.
55. Jackson, D. A., & King, A. R. (2004). Gender differences in the effects of oppositional behavior on teacher ratings of ADHD symptoms. Journal of Abnormal Child Psychology, 32 (2), 215-224.
56. Jacobs, E., Miller, L. C., & Tirella, L. G. (2010). Developmental and behavioral performance of internationally adopted preschoolers: A pilot study. Child Psychiatry and Human Development, 41 (1), 15-29.
57. Jensen, P. S., Martin, D., & Cantwell, D. P. (1997). Comorbidity in ADHD: Implications for research, practice, and DSM-V. Journal of the American Academy of Child and Adolescent Psychiatry, 36 (8), 1065-1079.
58. Johnson, K. A., Kelly, S. P., Bellgrove, M. A., Barry, E., Cox, M., Gill, M., et al. (2007). Response variability in attention deficit hyperactivity disorder: Evidence for neuropsychological heterogeneity. Neuropsychologia, 45 (4), 630-638. doi: 10.1016/j.neuropsychologia.2006.03.034.
59. Kebir, O., & Joober, R. (2011). Neuropsychological endophenotypes in attention-deficit/hyperactivity disorder: A review of genetic association studies. European Archives of Psychiatry and Clinical Neuroscience, 261 (8), 583-594. doi: 10.1007/s00406-011-0207-5.
60. Kendler, K. S., & Neale, M. C. (2010). Endophenotype: A conceptual analysis. Molecular Psychiatry, 15 (8), 789-797.
61. Kuntsi, J., Pinto, R., Price, T. S., van der Meere, J. J., Frazier-Wood, A. C., & Asherson, P. (2013). The separation of ADHD inattention and hyperactivity-impulsivity symptoms: Pathways from genetic effects to cognitive impairments and symptoms. Journal of Abnormal Child Psychology. doi: 10.1007/s10802-013-9771-7.
62. Kuntsi, J., Eley, T. C., Taylor, A., Hughes, C., Asherson, P., Caspi, A., et al. (2004). Co-occurrence of ADHD and low IQ has genetic origins. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 124B (1), 41-47.
63. Kuntsi, J., Rijsdijk, F., Ronald, A., Asherson, P., & Plomin, R. (2005). Genetic influences on the stability of attention-deficit/hyperactivity disorder symptoms from early to middle childhood. Biological Psychiatry, 57 (6), 647-654.
64. Kuntsi, J., Rogers, H., Swinard, G., Börger, N., Van Der Meere, J., Rijsdijk, F., et al. (2006). Reaction time, inhibition, working memory and "delay aversion" performance: Genetic influences and their interpretation. Psychological Medicine, 36 (11), 1613-1624.
65. Kuntsi, J., Wood, A. C., Rijsdijk, F., Johnson, K. A., Andreou, P., Albrecht, B., et al. (2010). Separation of cognitive impairments in attention-deficit/hyperactivity disorder into 2 familial factors. Archives of General Psychiatry, 67 (11), 1159-1167.
66. LaHoste, G. J., Swanson, J. M., Wigal, S. B., Glabe, C., Wigal, T., King, N., et al. (1996). Dopamine D4 receptor gene polymorphism is associated with attention deficit hyperactivity disorder. Molecular Psychiatry, 1 (2), 121-124.
67. Langley, K., Martin, J., Agha, S. S., Davies, C., Stergiakouli, E., Holmans, P., et al. (2011). Clinical and cognitive characteristics of children with attention-deficit hyperactivity disorder, with and without copy number variants. The British Journal of Psychiatry, 199 (5), 398-403.
68. Larsson, J.-O., Larsson, H., & Lichtenstein, P. (2004, October 1). Genetic and environmental contributions to stability and change of ADHD symptoms between 8 and 13 years of age: A Longitudinal Twin Study. Journal of the American Academy of Child and Adolescent Psychiatry, 43, 1267-75.
69. Larsson, H., Lichtenstein, P., & Larsson, J.-O. (2006). Genetic contributions to the development of ADHD subtypes from childhood to adolescence. Journal of the American Academy of Child and Adolescent Psychiatry, 45 (8), 973-981.
70. Lecendreux, M., Konofal, E., & Faraone, S. V. (2011). Prevalence of attention deficit hyperactivity disorder and associated features among children in France. Journal of Attention Disorders, 15 (6), 516-524.
71. Lesch, K.-P., Selch, S., Renner, T. J., Jacob, C., Nguyen, T. T., Hahn, T., et al. (2011). Genomewide copy number variation analysis in attention-deficit/hyperactivity disorder: Association with neuropeptide Y gene dosage in an extended pedigree. Molecular Psychiatry, 16 (5), 491- 503. doi: 10.1038/mp.2010.29.
72. Lesch, K.-P., Timmesfeld, N., Renner, T. J., Halperin, R., Röser, C., Nguyen, T. T., et al. (2008). Molecular genetics of adult ADHD: Converging evidence from genome-wide association and extended pedigree linkage studies. Journal of Neural Transmission (Vienna, Austria:1996), 115 (11), 1573-1585.
73. Levy, F., Hay, D. A., McStephen, M., Wood, C., & Waldman, I. (1997). Attention-deficit hyperactivity disorder: A category or a continuum? Genetic analysis of a large-scale twin study. Journal of the American Academy of Child and Adolescent Psychiatry, 36 (6), 737-744.
74. Li, D., Sham, P. C., Owen, M. J., & He, L. (2006). Meta-analysis shows significant association between dopamine system genes and attention deficit hyperactivity disorder (ADHD). Human Molecular Genetics, 15 (14), 2276-2284.
75. Lichtenstein, P., Carlstrom, E., Rastam, M., Gillberg, C., & Anckarsater, H. (2010). The genetics of autism spectrum disorders and related neuropsychiatric disorders in childhood. American Journal of Psychiatry, 167 (11), 1357-1363.
76. Loo, S. K., Rich, E. C., Ishii, J., McGough, J., McCracken, J., Nelson, S., et al. (2008). Cognitive functioning in affected sibling pairs with ADHD: Familial clustering and dopamine genes. The Journal of Child Psychology and Psychiatry and Allied Disciplines, 49 (9), 950-957.
77. Lowe, N., Kirley, A., Hawi, Z., Sham, P., Wickham, H., Kratochvil, C. J., et al. (2004). Joint analysis of the DRD5 marker concludes association with attention-deficit/hyperactivity disorder confined to the predominantly inattentive and combined subtypes. American Journal of Human Genetics, 74 (2), 348-356.
78. Maher, B. (2008). Personal genomes: The case of the missing heritability. Nature, 456 (7218), 18-21.
79. Manolio, T. A., Collins, F. S., Cox, N. J., Goldstein, D. B., Hindorff, L. A., Hunter, D. J., et al. (2009). Finding the missing heritability of complex diseases. Nature, 461 (7265), 747-753.
80. Marian, A. J. (2011). Molecular genetic studies of complex phenotypes. Translational Research, 159 (2), 64-79.
81. Martin, N., Levy, F., Pieka, J., & Hay, D. (2006). A genetic study of attention deficit hyperactivity disorder, conduct disorder, oppositional defiant disorder and reading disability: Aetiological overlaps and implications. International Journal of Disability, Development and Education, 53 (1), 21-34.
82. Martin, N. C., Piek, J. P., & Hay, D. (2006). DCD and ADHD: A genetic study of their shared aetiology. Human Movement Science, 25 (1), 110-124.
83. McLoughlin, G., Albrecht, B., Banaschewski, T., Rothenberger, A., Brandeis, D., Asherson, P., et al. (2009). Performance monitoring is altered in adult ADHD: A familial event-related potential investigation. Neuropsychologia, 47 (14), 3134-3142.
84. McLoughlin, G., Asherson, P., Albrecht, B., Banaschewski, T., Rothenberger, A., Brandeis, D., et al. (2011). Cognitive-electrophysiological indices of attentional and inhibitory processing in adults with ADHD: Familial effects. Behavioral and Brain Functions, 7, 26.
85. McLoughlin, G., Rijsdijk, F., Asherson, P., & Kuntsi, J. (2011). Parents and teachers make different contributions to a shared perspective on hyperactive-impulsive and inattentive symptoms: A multivariate analysis of parent and teacher ratings on the symptom domains of ADHD. Behavior Genetics, 41 (5), 668-679.
86. McLoughlin, G., Ronald, A., Kuntsi, J., Asherson, P., & Plomin, R. (2007). Genetic support for the dual nature of attention deficit hyperactivity disorder: Substantial genetic overlap between the inattentive and hyperactive-impulsive components. Journal of Abnormal Child Psychology, 35 (6), 999-1008.
87. Merwood, A., & Asherson, P. (2011). Attention deficit hyperactivity disorder: A lifespan genetic perspective. Advances in Mental Health and Intellectual Disabilities, 5 (4), 33-46.
88. Meyer-Lindenberg, A., & Weinberger, D. R. (2006). Intermediate phenotypes and genetic mechanisms of psychiatric disorders. Nature Reviews. Neuroscience, 7 (10), 818-827.
89. Mulder, M. J., Baeyens, D., Davidson, M. C., Casey, B. J., Van Den Ban, E., Van Engeland, H., et al. (2008). Familial vulnerability to ADHD affects activity in the cerebellum in addition to the prefrontal systems. Journal of the American Academy of Child & Adolescent Psychiatry, 47 (1), 68-75.
90. Mulder, M. J., Van Belle, J., Van Engeland, H., & Durston, S. (2011). Functional connectivity between cognitive control regions is sensitive to familial risk for ADHD. Human Brain Mapping, 32 (9), 1511-1518.
91. Nadder, T. S., Rutter, M., Silberg, J. L., Maes, H. H., & Eaves, L. J. (2002). Genetic effects on the variation and covariation of attention deficit-hyperactivity disorder (ADHD) and oppositionaldefiant disorder/conduct disorder (Odd/CD) symptomatologies across informant and occasion of measurement. Psychological Medicine, 32 (1), 39-53.
92. Neale, M. C., Eaves, L. J., & Kendler, K. S. (1994). The power of the classical twin study to resolve variation in threshold traits. Behavior Genetics, 24 (3), 239-258.
93. Neale, B. M., Medland, S., Ripke, S., Anney, R. J. L., Asherson, P., Buitelaar, J., et al. (2010). Case-control genome-wide association study of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 49 (9), 906-920.
94. Neale, B. M., Medland, S. E., Ripke, S., Asherson, P., Franke, B., Lesch, K.-P., et al. (2010). Metaanalysis of genome-wide association studies of attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 49 (9), 884-897.
95. Nigg, J., Nikolas, M., & Burt, S. A. (2010). Measured gene-by-environment interaction in relation to attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 49 (9), 863-873.
96. Nikolas, M. A., & Burt, S. A. (2010). Genetic and environmental influences on ADHD symptom dimensions of inattention and hyperactivity: A meta-analysis. Journal of Abnormal Psychology, 119 (1), 1-17.
97. Nikolas, M., Klump, K. L., & Burt, S. A. (2012). Youth appraisals of inter-parental conflict and genetic and environmental contributions to attention-deficit hyperactivity disorder: Examination of GxE effects in a twin sample. Journal of Abnormal Child Psychology, 40 (4), 543-554.
98. O'Connell, R. G., Bellgrove, M. A., Dockree, P. M., Lau, A., Fitzgerald, M., & Robertson, I. H. (2008). Self- alert training: Volitional modulation of autonomic arousal improves sustained attention. Neuropsychologia, 46 (5), 1379-1390.
99. Paloyelis, Y., Rijsdijk, F., Wood, A. C., Asherson, P., & Kuntsi, J. (2010). The genetic association between ADHD symptoms and reading difficulties: The role of inattentiveness and IQ. Journal of Abnormal Child Psychology, 38 (8), 1083-1095.
100. Poelmans, G., Pauls, D. L., Buitelaar, J. K., & Franke, B. (2011). Integrated genome-wide association study findings: Identification of a neurodevelopmental network for attention deficit hyperactivity disorder. The American Journal of Psychiatry, 168 (4), 365-377.
101. Polanczyk, G., de Lima, M. S., Horta, B. L., Biederman, J., & Rohde, L. A. (2007). The worldwide prevalence of ADHD: A systematic review and metaregression analysis. American Journal of Psychiatry, 164 (6), 942-948.
102. Polanczyk, G., & Rohde, L. A. (2007). Epidemiology of attention-deficit/hyperactivity disorder across the lifespan. Current Opinion in Psychiatry, 20 (4), 386-392.
103. Price, T. S., Simonoff, E., Asherson, P., Curran, S., Kuntsi, J., Waldman, I., et al. (2005). Continuity and change in preschool ADHD symptoms: Longitudinal genetic analysis with contrast effects. Behavior Genetics, 35 (2), 121-132.
104. Reiersen, A. M., Constantino, J. N., Grimmer, M., Martin, N. G., & Todd, R. D. (2008). Evidence for shared genetic influences on self-reported ADHD and autistic symptoms in young adult Australian twins. Twin Research and Human Genetics, 11 (6), 579-585.
105. Rietveld, M. J. H., Hudziak, J. J., Bartels, M., van Beijsterveldt, C. E. M., & Boomsma, D. I. (2003). Heritability of attention problems in children: I. Cross-sectional results from a study of twins, age 3-12 years. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 117B (1), 102-113.
106. Rietveld, M. J. H., Hudziak, J. J., Bartels, M., van Beijsterveldt, C. E. M., & Boomsma, D. I. (2004). Heritability of attention problems in children: Longitudinal results from a study of twins, age 3 to 12. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 45 (3), 577-588.
107. Rietveld, M. J. H., Posthuma, D., Dolan, C. V., & Boomsma, D. I. (2003). ADHD: Sibling interaction or dominance: An evaluation of statistical power. Behavior Genetics, 33 (3), 247-255.
108. Rommelse, N. N. J., Altink, M. E., Oosterlaan, J., Buschgens, C. J. M., Buitelaar, J., & Sergeant, J. A. (2008). Support for an independent familial segregation of executive and intelligence endophenotypes in ADHD families. Psychological Medicine, 38 (11), 1595-1606.
109. Rommelse, N. N. J., Franke, B., Geurts, H. M., Hartman, C. A., & Buitelaar, J. K. (2010). Shared heritability of attention-deficit/hyperactivity disorder and autism spectrum disorder. European Child & Adolescent Psychiatry, 19 (3), 281-295.
110. Ronald, A., Edelson, L. R., Asherson, P., & Saudino, K. J. (2010). Exploring the relationship between autistic-like traits and ADHD behaviors in early childhood: Findings from a community twin study of 2-year-olds. Journal of Abnormal Child Psychology, 38 (2), 185-196.
111. Ronald, A., Happé, F., & Plomin, R. (2005). The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism. Developmental Science, 8 (5), 444-458.
112. Ronald, A., Simonoff, E., Kuntsi, J., Asherson, P., & Plomin, R. (2008). Evidence for overlapping genetic influences on autistic and ADHD behaviours in a community twin sample. Journal of Child Psychology and Psychiatry, 49 (5), 535-542.
113. Rutter, M., Macdonald, H., Couteur, A., Harrington, R., Bolton, P., & Bailey, A. (1990). Genetic factors in child psychiatric disorders? II. Empirical findings. Journal of Child Psychology and Psychiatry, 31 (1), 39-83.
114. Saudino, K. J., Ronald, A., & Plomin, R. (2005). The etiology of behavior problems in 7-year-old twins: Substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers. Journal of Abnormal Child Psychology, 33 (1), 113-130.
115. Semrud-Clikeman M., Biederman J., Sprich-Buckminster S., Lehman B. K., Faraone S. V., Norman D. (1992). Comorbidity between ADHD and learning disability: a review and report in a clinically referred sample. J Am Acad Child Adolesc Psychiatry, 31(3), 439-448.
116. Shang, C. Y., & Gau, S. S. (2011). Visual memory as a potential cognitive endophenotype of attention deficit hyperactivity disorder. Psychological Medicine, 41, 2603-2614.
117. Sherman, D. K., Iacono, W. G., & McGue, M. K. (1997). Attention-deficit hyperactivity disorder dimensions: A twin study of inattention and impulsivity-hyperactivity. Journal of the American Academy of Child and Adolescent Psychiatry, 36 (6), 745-753.
118. Simon, V., Czobor, P., Bálint, S., Mészáros, A., & Bitter, I. (2009). Prevalence and correlates of adult attention-deficit hyperactivity disorder: Meta-analysis. The British Journal of Psychiatry, 194 (3), 204-211.
119. Slaats-Willemse, D. I. E., Swaab-Barneveld, H. J. T., De Sonneville, L. M. J., & Buitelaar, J. K. (2007). Family-genetic study of executive functioning in attention-deficit/hyperactivity disorder: Evidence for an endophenotype? Neuropsychology, 21 (6), 751-760.
120. Smalley, S. L., McGough, J. J., Del'Homme, M., NewDelman, J., Gordon, E., Kim, T., et al. (2000). Familial clustering of symptoms and disruptive behaviors in multiplex families with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry, 39 (9), 1135-1143.
121. Sprich, S., Biederman, J., Crawford, M. H., Mundy, E., & Faraone, S. V. (2000). Adoptive and biological families of children and adolescents with ADHD. Journal of the American Academy of Child and Adolescent Psychiatry, 39 (11), 1432-1437.
122. Stawicki, J. A., Nigg, J. T., & von Eye, A. (2006). Family psychiatric history evidence on the nosological relations of DSM-IV ADHD combined and inattentive subtypes: New data and meta-analysis. The Journal of Child Psychology and Psychiatry and Allied Disciplines, 47 (9), 935-945.
123. Stergiakouli, E., Hamshere, M., Holmans, P., Langley, K., Zaharieva, I., Hawi, Z., et al. (2011). Investigating the contribution of common genetic variants to the risk and pathogenesis of ADHD. The American Journal of Psychiatry, 169 (2), 186-194.
124. Stergiakouli, E., & Thapar, A. (2010). Fitting the pieces together: Current research on the genetic basis of attention-deficit/hyperactivity disorder (ADHD). Neuropsychiatric Disease and Treatment, 6, 551-560.
125. Sturm, H., Fernell, E., & Gillberg, C. (2007). Autism spectrum disorders in children with normal intellectual levels: Associated impairments and subgroups. Developmental Medicine & Child Neurology, 46 (7), 444-447.
126. Swanson, J. M., Sunohara, G. A., Kennedy, J. L., Regino, R., Fineberg, E., Wigal, T., et al. (1998). Association of the dopamine receptor D4 (DRD4) gene with a refined phenotype of attention deficit hyperactivity disorder (ADHD): A family-based approach. Molecular Psychiatry, 3 (1), 38-41.
127. Szatmari, P., Boyle, M. H., & Offord, D. R. (1993). Familial aggregation of emotional and behavioral problems of childhood in the general population. The American Journal of Psychiatry, 150 (9), 1398-1403.
128. Takeda, T., Stotesbery, K., Power, T., Ambrosini, P. J., Berrettini, W., Hakonarson, H., et al. (2010). Parental ADHD status and its association with proband ADHD subtype and severity. Journal of Pediatrics, 157 (6), 995-1000.e1.
129. Thapar, A., Harrington, R., & McGuffin, P. (2001). Examining the comorbidity of ADHD-related behaviours and conduct problems using a twin study design. The British Journal of Psychiatry, 179 (3), 224-229.
130. Todd, R. D., Rasmussen, E. R., Neuman, R. J., Reich, W., Hudziak, J. J., & Bucholz, K. K. (2001). Familiality and heritability of subtypes of attention deficit hyperactivity disorder in a population sample of adolescent female twins. American Journal of Psychiatry, 158, 1891-1898.
131. Trzesniewski, K. H., Moffitt, T. E., Caspi, A., Taylor, A., & Maughan, B. (2006). Revisiting the association between reading achievement and antisocial behavior: New evidence of an environmental explanation from a twin study. Child Development, 77 (1), 72-88.
132. Tuvblad, C., Zheng, M., Raine, A., & Baker, L. (2009). A common genetic factor explains the covariation among ADHD ODD and CD symptoms in 9-10 year old boys and girls. Journal of Abnormal Child Psychology, 37 (2), 153-167.
133. Tye, C., McLoughlin, G., Kuntsi, J., & Asherson, P. (2011, March). Electrophysiological markers of genetic risk for attention deficit hyperactivity disorder. Expert Reviews in Molecular Medicine, 13, e9.
134. Tye, C., Rijsdijk, F. V., Greven, C. U., Kuntsi, J., Asherson, P., & McLoughlin, G. (2011). Genetic overlap between ADHD symptoms and very low frequency neuronal activity. Journal of Child Psychology and Psychiatry, 53, 706-715.
135. Uebel, H., Albrecht, B., Asherson, P., Börger, N. A., Butler, L., Chen, W., et al. (2010). Performance variability, impulsivity errors and the impact of incentives as gender-independent endophenotypes for ADHD. The Journal of Child Psychology and Psychiatry and Allied Disciplines, 51 (2), 210-218.
136. Ullebø, A. K., Breivik, K., Gillberg, C., Lundervold, A. J., & Posserud, M.-B. (2012). The factor structure of ADHD in a general population of primary school children. Journal of Child Psychology and Psychiatry and Allied Disciplines, 53 (9), 927-936.
137. Ullebø, A. K., Posserud, M.-B., Heiervang, E., Obel, C., & Gillberg, C. (2012). Prevalence of the ADHD phenotype in 7- to 9-year-old children: Effects of informant, gender and nonparticipation. Social Psychiatry and Psychiatric Epidemiology, 47 (5), 763-769.
138. Vierikko, E., Pulkkinen, L., Kaprio, J., & Rose, R. J. (2004). Genetic and environmental influences on the relationship between aggression and hyperactivity-impulsivity as rated by teachers and parents. Twin Research, 7 (3), 14.
139. Wiik, K. L., Loman, M. M., Van Ryzin, M. J., Armstrong, J. M., Essex, M. J., Pollak, S. D., et al. (2011). Behavioral and emotional symptoms of post-institutionalized children in middle childhood. Journal of Child Psychology and Psychiatry, and Allied Disciplines, 52 (1), 56-63.
140. Willcutt, E. G., Betjemann, R. S., McGrath, L. M., Chhabildas, N. A., Olson, R. K., DeFries, J. C., et al. (2010). Etiology and neuropsychology of comorbidity between RD and ADHD: The case for multiple-deficit models. Cortex, 46 (10), 1345-1361.
141. Willcutt, E. G., & Pennington, B. F. (2000a). Comorbidity of reading disability and attention- defi- cit/hyperactivity disorder: Differences by gender and subtype. Journal of Learning Disabilities, 33 (2), 179-191.
142. Willcutt, E. G., & Pennington, B. F. (2000b). Psychiatric comorbidity in children and adolescents with reading disability. The Journal of Child Psychology and Psychiatry and Allied Disciplines, 41 (8), 1039-1048.
143. Willcutt, E. G., Pennington, B. F., & DeFries, J. C. (2000). Twin study of the etiology of comorbidity between reading disability and attention-deficit/hyperactivity disorder. American Journal of Medical Genetics, 96 (3), 293-301.
144. Willcutt, E. G., Pennington, B. F., Olson, R. K., & DeFries, J. C. (2007). Understanding comorbidity: A twin study of reading disability and attention-deficit/hyperactivity disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 144B (6), 709-714.
145. Williams, N. M., Zaharieva, I., Martin, A., Langley, K., Mantripragada, K., Fossdal, R., et al. (2010). Rare chromosomal deletions and duplications in attention-deficit hyperactivity disorder: A genome-wide analysis. Lancet, 376 (9750), 1401-1408.
146. Wood, A. C., Asherson, P., Rijsdijk, F., & Kuntsi, J. (2009). Is overactivity a core feature in ADHD? Familial and receiver operating characteristic curve analysis of mechanically assessed activity level. Journal of the American Academy of Child and Adolescent Psychiatry, 48 (10), 1023-1030.
147. Wood, A. C., Asherson, P., Van der Meere, J. J., Asherson, P., & Kuntsi, J. (2010). Separation of genetic influences on ADHD symptoms and reaction time performance from those on IQ. Psychological Medicine, 40 (6), 1027-1037.
148. Wood, A. C., Buitelaar, J., Rijsdijk, F., Asherson, P., & Kuntsi, J. (2010). Rethinking shared environment as a source of variance underlying attention-deficit/hyperactivity disorder symptoms: Comment on Burt (2009). Psychological Bulletin, 136 (3), 331-340.
149. Wood, A. C., Rijsdijk, F., Asherson, P., & Kunsti J. (in press) Hyperactive-impulsive symptom scores and oppositional behaviours reflect alternate manifestations of a single liability. Behavior Genetics, 39 (5).
150. Wood, A. C., Rijsdijk, F., Johnson, K. A., Andreou, P., Albrecht, B., Arias-Vasquez, A., et al. (2011). The relationship between ADHD and key cognitive phenotypes is not mediated by shared familial effects with IQ. Psychological Medicine, 41 (4), 861-871.
151. Zhou, K., Dempfle, A., Arcos-Burgos, M., Bakker, S. C., Banaschewski, T., Biederman, J., et al. (2008). Meta-analysis of genome-wide linkage scans of attention deficit hyperactivity disorder. American Journal of Medical Genetics. Part B, Neuropsychiatric Genetics, 147B (8), 1392-1398.