The genetic relationship between individual differences in social and nonsocial behaviours characteristic of autism

Developmental Science

Volumn 8, Issue 5, 2005, Pages 444-458

  Ronald, Angelica ^a   Happé, Francesca ^a   Plomin, Robert ^a  

^a KING'S COLLEGE LONDON   (United Kingdom)

Author keywords

[No Author keywords available]

Indexed keywords

AUTISM; CHILD; CHILD BEHAVIOR; FEMALE; GENETICS; HUMAN; HUMAN RELATION; INDIVIDUALITY; MALE; PARENT; PHENOTYPE; REVIEW; SEX DIFFERENCE; SOCIAL BEHAVIOR; TIME; TWINS;

AUTISTIC DISORDER; CHILD; CHILD BEHAVIOR; DISEASES IN TWINS; FEMALE; HUMANS; INDIVIDUALITY; INTERPERSONAL RELATIONS; MALE; PARENTS; PHENOTYPE; SEX FACTORS; SOCIAL BEHAVIOR; TIME FACTORS;

EID: 23744468693     PISSN: 1363755X     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1467-7687.2005.00433.x     Document Type: Review

References (59)

1. Achenbach, T.M., McConaughy, S.H., & Howell, C.T. (1987). Child/adolescent behavioural and emotional problems: implications of cross-informant correlations for situational specificity. Psychological Bulletin, 101, 213-232.
2. American Psychiatric Association. (1994). Diagnostic and statistical manual of mental disorders (4th edn.). Washington, DC: Author.
3. Andres, C. (2002). Molecular genetics and animal models in autistic disorder. Brain Research Bulletin, 57, 109-119.
4. Bailey, A., Le Couteur, A., Gottesman, I., Bolton, P., Simonoff, E., Yuzda, E., & Rutter, M. (1995). Autism as a strongly genetic disorder: evidence from a British twin study. Psychological Medicine, 25, 63-77.
5. Bailey, A., Palferman, S., Heavey, L., & Le Couteur, A. (1998). Autism: the phenotype in relatives. Journal of Autism and Developmental Disorders, 28, 369-392.
6. Baird, G., Charman, T., Baron-Cohen, S., Cox, A., Swettenham, J., Wheelwright, S., & Drew, A. (2000). A screening instrument for autism at 18 months of age: a 6-year follow-up study. Journal of the American Academy of Child and Adolescent Psychiatry, 39, 694-702.
7. Bradford, Y., Haines, J., Hutcheson, H., Gardiner, M., Braun, T., Sheffield, V., Cassavant, T., Huang, W., Wang, K., Vieland, V., Folstein, S., Santangelo, S., & Piven, J. (2001). Incorporating language phenotypes strengthens evidence of linkage to autism. American Journal of Medical Genetics, 105, 539-547.
8. Buxbaum, J.D., Silverman, J.M., Smith, C.J., Kilifarski, M., Reichert, J., Hollander, E., Lawlor, B.A., Fitzgerald, M., Greenberg, D.A., & Davis, K.L. (2001). Evidence for a susceptibility gene for autism on chromosome 2 and for genetic heterogeneity. American Journal of Human Genetics, 68, 1514-1520.
9. Chakrabarti, S., & Fombonne, E. (2001). Pervasive developmental disorders in preschool children. Journal of the American Medical Association, 285, 3093-3099.
10. Constantino, J.N., Przybeck, T., Friesen, D., & Todd, R.D. (2000). Reciprocal social behaviour in children with and without pervasive developmental disorders. Journal of Developmental and Behavioural Pediatrics, 21, 2-11.
11. Constantino, J.N., & Todd, R.D. (2000). Genetic structure of reciprocal social behaviour. American Journal of Psychiatry, 157, 2043-2045.
12. Constantino, J.N., & Todd, R.D. (2003). Autistic traits in the general population: a twin study. Archives of General Psychiatry, 60, 524-530.
13. Department for Education and Skills. (2002). Special Educational Needs in England: January, 2002 Bulletin. London: Author.
14. Eaves, L., Eysenck, H.J., & Martin, N.G. (1989). Genes, culture, and personality: An empirical approach. London: Academic Press.
15. Eaves, L.J., Heath, A.C., Neale, M.C., Hewitt, J.K., & Martin, N.G. (1998). Sex differences and non-additivity in the effects of genes on personality. Twin Research, 1, 131-137.
16. Ehlers, S., Gillberg, C., & Wing, L. (1999). A screening questionnaire for Asperger syndrome and other high-functioning autism spectrum disorders in school age children. Journal of Autism and Developmental Disorders, 29, 129-141.
17. Folstein, S.E., Dowd, M., Mankoski, R., & Tadevosyan, O. (2003). How might genetic mechanisms operate in autism? Novartis Foundation Symposium, 251, 70-80.
18. Folstein, S.E., & Rosen-Sheidley, B. (2001). Genetics of autism: complex aetiology for a heterogeneous disorder. Nature Reviews Genetics, 2, 943-955.
19. Folstein, S.E., & Rutter, M. (1977). Infantile autism: a genetic study of 21 twin pairs. Journal of Child Psychology & Psychiatry & Allied Disciplines, 18, 297-321.
20. Fombonne, E. (2003). The prevalence of autism. Journal of the American Medical Association, 289, 87-89.
21. Frith, U., Happé, F., & Siddons, F. (1994). Autism and theory of mind in everyday life. Social Development, 3, 108-124.
22. Gillberg, C., & Wing, L. (1999). Autism: not an extremely rare disorder. Acta Psychiatrica Scandinavica, 99, 399-406.
23. Goodman, R. (1997). The Strengths and Difficulties Questionnaire: A research note. Journal of Child Psychology & Psychiatry & Allied Disciplines, 38, 581-586.
24. Happé, F. (2001). Social and nonsocial development in autism: where are the links? In J.A. Burack, T. Charman, N. Yirmiya, & P.R. Zelazo (Eds.), The development of autism: Perspectives from theory and research (pp. 237-253). Hillsdale, NJ: Lawrence Erlbaum Associates.
25. Happé, F. (2003). Cognition in autism: one deficit or many? Novartis Foundation Symposium, 251, 198-207.
26. Hollander, E., DelGiudice-Asch, G., Simon, L., Schmeidler, J., Cartwright, C., DeCaria, C.M., Kwon, J., Cunningham-Rundles, C., Chapman, F., & Zabriskie, J.B. (1999). B lymphocyte antigen D8/17 and repetitive behaviours in autism. American Journal of Psychiatry, 156, 317-320.
27. Hollander, E., Novotny, S., Allen, A., Aronowitz, B., Cartwright, C., & DeCaria, C. (2000). The relationship between repetitive behaviours and growth hormone response to sumatriptan challenge in adult autistic disorder. Neuropsychopharmacology, 22, 163-167.
28. Kanner, L. (1943). Autistic disturbances of affective contact. Nervous Child, 2, 217-250.
29. Mahoney, W.J., Szatmari, P., MacLean, J.E., Bryson, S.E., Bartolucci, G., Walter, S.D., Jones, M.B., & Zwaigenbaum, L. (1998). Reliability and accuracy of differentiating pervasive developmental disorder subtypes. Journal of the American Academy of Child & Adolescent Psychiatry, 37, 278-285.
30. Najman, J.M., Williams, G.M., Nikles, J., Spence, S., Bor, W., O'Callaghan, M., Le Brocque, R., Andersen, M.J., & Shuttlewood, G.J. (2001). Bias influencing maternal reports of child behaviour and emotional state. Social Psychiatry and Psychiatric Epidemiology, 36, 186-194.
31. Neale, M.C., Boker, S.M., Xie, G., & Maes, H.H. (2002). Mx Statistical Modeling (6th edn.). VCU Box 900126, Richmond, VA 23298: Department of Psychiatry.
32. Neale, M.C., & Cardon, L.R. (1992). Methodology for genetic studies of twins and families. Dordrecht: Kluwer.
33. Neale, M.C., & Stevenson, J. (1989). Rater bias in the EASI temperament scales: a twin study. Journal of Personality and Social Psychology, 56, 446-455.
34. Nurmi, E.L., Dowd, M., Tadevosyan-Leyfer, O., Haines, J.L., Folstein, S.E., & Sutcliffe, J.S. (2003). Exploratory subsetting of Autism families based on savant skills improves evidence of genetic linkage to 15q11-q13. Journal of the American Academy of Child & Adolescent Psychiatry, 42, 856-863.
35. Office for National Statistics. (2002). Living in Britain: Results from the 2000/01 General Household Survey. Norwich: The Stationery Office.
36. Pickles, A., Starr, E., Kazak, S., Bolton, P., Papanikolaou, K., Bailey, A., Goodman, R., & Rutter, M. (2000). Variable expression of the autism broader phenotype: findings from extended pedigrees. Journal of Child Psychology & Psychiatry & Allied Disciplines, 41, 491-502.
37. Piven, J., Palmer, P., Jacobi, D., Childress, D., & Arndt, S. (1997). Broader autism phenotype: evidence from a family history study of multiple-incidence autism families. American Journal of Psychiatry, 154, 185-190.
38. Plomin, R., DeFries, J.C., McClearn, G.E., & McGuffin, P. (2001). Behavioral genetics (4th edn.). New York: Worth.
39. Price, T.S., Freeman, B., Craig, I., Petrill, S.A., Ebersole, L., & Plomin, R. (2000). Infant zygosity can be assigned by parental report questionnaire data. Twin Research, 3, 129-133.
40. Rietveld, M.J., Posthuma, D., Dolan, C.V., & Boomsma, D.L. (2003). ADHD: sibling interaction or dominance: an evaluation of statistical power. Behavior Genetics, 33, 247-255.
41. Rutter, M. (2000). Genetic studies of autism: from the 1970s into the millennium. Journal of Abnormal Child Psychology, 28, 3-14.
42. Rutter, M., Bailey, A., Berument, S.K., Lord, C., & Pickles, A. (2003). Social Communication Questionnaire (SCQ). Los Angeles, CA: Western Psychological Services.
43. Rutter, M., Silberg, J., O'Connor, T., & Simonoff, E. (1999). Genetics and child psychiatry: II Empirical research findings. Journal of Child Psychology & Psychiatry & Allied Disciplines, 40, 19-55.
44. Saudino, K., Ronald, A., & Plomin, R. (2005). The aetiology of behaviour problems in 7-year-old twins: substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers. Journal of Abnormal Child Psychology, 33 (1), 113-130.
45. Scourfield, J., Martin, N., Lewis, G., & McGuffin, P. (1999). Heritability of social cognitive skills in children and adolescents. British Journal of Psychiatry, 175, 559-564.
46. Shao, Y., Cuccaro, M.L., Hauser, E.R., Raiford, K.L., Menold, M.M., Wolpert, C.M., Ravan, S.A., Elston, L., Decena, K., Donnelly, S.L., Abramson, R.K., Wright, H.H., DeLong, G.R., Gilbert, J.R., & Pericak-Vance, M.A. (2003). Fine mapping of autistic disorder to chromosome 15q11-q13 by use of phenotypic subtypes. American Journal of Human Genetics, 72, 539-548.
47. Shao, Y., Raiford, K.L., Wolpert, C.M., Cope, H.A., Ravan, S.A., Ashley-Koch, A.A., Abramson, R.K., Wright, H.H., DeLong, G.R., Gilbert, J.R., Cuccaro, M.L., & Pericak-Vance, M.A. (2002). Phenotypic homogeneity provides increased support for linkage on chromosome 2 in autistic disorder. American Journal of Human Genetics, 70, 1058-1061.
48. Shrout, P.E., & Fleiss, J. (1979). Intraclass correlations: uses in assessing rater reliability. Psychological Bulletin, 86, 420-428.
49. Simonoff, E., Pickles, A., Hervas, A., Silberg, J.L., Rutter, M., & Eaves, L. (1998). Genetic influences on childhood hyperactivity: contrast effects imply parental rating bias, not sibling interaction. Psychological Medicine, 28, 825-837.
50. Spinath, F.M., Walker, S.O., Saudino, K.J., & Plomin, R. (2004). Genetic influences on teacher assessed academic achievement and general cognitive ability: a bivariate twin study in 7-year-old twins. Manuscript submitted for publication.
51. Steffenburg, S., Gillberg, C., Hellgren, L., Andersson, L., Gillberg, I.C., Jakobsson, G., & Bohman, M. (1989). A twin study of autism in Denmark, Finland, Iceland, Norway and Sweden. Journal of Child Psychology & Psychiatry & Allied Disciplines, 30, 405-416.
52. Szatmari, P. (2000). The classification of autism, Asperger's syndrome, and pervasive developmental disorder. Canadian Journal of Psychiatry, 45, 731-738.
53. Szatmari, P., Archer, L., Fisman, S., & Streiner, D.L. (1994). Parent and teacher agreement in the assessment of pervasive developmental disorders. Journal of Autism and Developmental Disorders, 24, 703-717.
54. Szatmari, P., MacLean, J.E., Jones, M.B., Bryson, S.E., Zwaigenbaum, L., Bartolucci, G., Mahoney, W.J., & Tuff, L. (2000). The familial aggregation of the lesser variant in biological and nonbiological relatives of PDD probands: a family history study. Journal of Child Psychology & Psychiatry & Allied Disciplines, 41, 579-586.
55. Trouton, A., Spinath, F.M., & Plomin, R. (2002). Twins Early Development Study (TEDS): a multivariate, longitudinal genetic investigation of language, cognition and behaviour problems in childhood. Twin Research, 5, 444-448.
56. Walker, D.R., Thompson, A., Zwaigenbaum, L., Goldberg, J., Bryson, S.E., Mahoney, W.J., Strawbridge, C.P., & Szatmari, P. (2004). Specifying PDD-NOS: a comparison of PDD-NOS, Asperger syndrome, and autism. Journal of the American Academy of Child & Adolescent Psychiatry, 43, 172-180.
57. Wing, L. (1997). The autistic spectrum. Lancet, 350, 1761-1766.
58. Wing, L., & Gould, J. (1979). Severe impairments of social interaction and associated abnormalities in children: epidemiology and classification. Journal of Autism and Developmental Disorders, 9, 11-29.
59. Yeargin-Allsopp, M., Rice, C., Karapurkar, T., Doernberg, N., Boyle, C., & Murphy, C. (2003). Prevalence of autism in a US metropolitan area. Journal of the American Medical Association, 289, 49-55.