Genetic and Environmental Influences on ADHD Symptom Dimensions of Inattention and Hyperactivity: A Meta-Analysis

Journal of Abnormal Psychology

Volumn 119, Issue 1, 2010, Pages 1-17

  Nikolas, Molly A ^a   Burt, S Alexandra ^a  

^a MICHIGAN STATE UNIVERSITY   (United States)

Author keywords

etiology; genetic; hyperactivity; inattention

Indexed keywords

AGE; ALLELE; ARTICLE; ATTENTION DEFICIT DISORDER; DIAGNOSTIC AND STATISTICAL MANUAL OF MENTAL DISORDERS; DISEASE CLASSIFICATION; ENVIRONMENTAL FACTOR; GENDER; GENETIC ANALYSIS; HEREDITY; HUMAN; NEUROPSYCHOLOGICAL TEST; NEUROTRANSMISSION; PHENOTYPE; SYMPTOM;

EID: 77249117774     PISSN: 0021843X     EISSN: None     Source Type: Journal    
DOI: 10.1037/a0018010     Document Type: Article

References (82)

1. Achenbach T.M., and Rescorla L.A. Manual for the ASEBA School-Age Forms & Profiles (2001), University of Vermont, Research Center for Children, Youth & Families, Burlington, VT
2. Akaike H. Factor analysis and AIC. Psychometrika 52 (1987) 317-322
3. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 3rd ed., rev. (1987), Author, Washington, DC
4. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed. (1994), Author, Washington, DC
5. American Psychiatric Association. Diagnostic and statistical manual of mental disorders. 4th ed., text rev. (2000), Author, Washington, DC
6. Barkley R.A. Attention-deficit hyperactivity disorder: A handbook for diagnosis and treatment. 3rd ed. (2006), Guilford Press, New York, NY
7. Bergen S.E., Gardner C.O., and Kendler K.S. Age-related changes in heritability of behavioral phenotypes over adolescence and young adulthood: A meta-analysis. Twin Research and Human Genetics 10 (2007) 423-433
8. Breslau J., Lane M., Sampson N., and Kessler R.C. Mental disorders and subsequent educational attainment in a US national sample. Journal of Psychiatric Research 42 (2008) 708-716
9. Brookes K., Xu X., Chen W., Zhou K., Neale B., Lowe N., and Johansson L. The analysis of 51 genes in DSM-IV combined type attention deficit hyperactivity disorder: Association signals in DRD4, DAT1, and 16 other genes. Molecular Psychiatry 11 (2006) 934-953
10. Burt S.A. Rethinking environmental contributions to child and adolescent psychopathology: A meta-analysis of shared environmental influences. Psychological Bulletin 135 (2009) 608-637
11. Burt S.A., Krueger R.F., McGue M., and Iacono W. Sources of covariation among attention deficit hyperactivity disorder, oppositional defiant disorder, and conduct disorder: The importance of the shared environment. Journal of Abnormal Psychology 110 (2001) 516-525
12. Connors C.K. Connors' Rating Scales-Revised (1997), Multi Health Systems, Inc, Toronto, Ontario, Canada
13. Derks E.M., Dolan C.V., Hudziak J.J., Neale M.C., and Boomsma D.I. Assessment and etiology of attention deficit hyperactivity disorder and oppositional defiant disorder in boys and girls. Behavior Genetics 37 (2007) 559-566
14. Derks E.M., Hudziak J.J., van Beijsterveldt C.E.M., Dolan C.V., and Boomsma D.I. A study of genetic and environmental influences on maternal and paternal CBCL syndrome scores in a large sample of Dutch 3-year-old twins. Behavior Genetics 34 (2004) 571-583
15. Dick D.M., Viken R.J., Kaprio J., Pulkkinen L., and Rose R.J. Understanding the covariation among childhood externalizing symptoms: Genetic and environmental influences on conduct disorder, attention-deficit hyperactivity disorder, and oppositional defiant disorder symptoms. Journal of Abnormal Child Psychology 33 (2005) 219-229
16. Duncan G.J., Dowsett C.J., Claessens A., Magnuson J., Huston A.C., Klebanov P., and Duckworth K. School readiness and later achievement. Developmental Psychology 43 (2007) 1428-1446
17. DuPaul G.J., Power T.J., Anastopoulos A.D., and Reid R. The ADHD Rating Scale IV: Checklists, norms, and clinical interpretation (1998), Guilford Press, New York, NY
18. Eaves L., Rutter M., Silberg J.L., Shillady L., Maes H., and Pickles A. Genetic and environmental causes of covariation in interview assessments of disruptive behavior in child and adolescent twins. Behavior Genetics 30 (2000) 321-334
19. Eaves L.J., Silberg J.L., Meyer J.M., and Maes H.H. Genetics and developmental psychopathology: 2. The main effects of genes and environment on behavior problems in the Virginia Twin Study of Adolescent Behavioral Development. Journal of Child Psychology and Psychiatry 38 (1997) 965-980
20. Edelbrock C., Rende R., Plomin R., and Thompson L.A. A twin study of competence problem behavior in early childhood and adolescence. Journal of Child Psychology and Psychiatry 36 (1995) 775-785
21. Eiraldi R.B., Power T.J., and Nezu C.M. Patterns of comorbidity associated with subtypes of attention deficit hyperactivity disorder among 6 to 12-year old children. Journal of the American Academy of Child and Adolescent Psychiatry 36 (1997) 503-514
22. Elkins I.J., McGue M., and Iacono W.G. Prospective effects of attention-deficit hyperactivity disorder, conduct disorder, and sex on adolescent substance use and abuse. Archives of General Psychiatry 64 (2007) 1145-1152
23. Faraone S.V., Biederman J., and Friedman D. Validity of DSM-IV subtypes of attention deficit/hyperactivity disorder: A family study perspective. Journal of the American Academy of Child and Adolescent Psychiatry 39 (2000) 300-309
24. Faraone S.V., Perlis R.H., Doyle A.E., Smoller J.W., Goralnick J.J., Holmgren M.A., and Sklar P. Molecular genetics of ADHD. Biological Psychiatry 57 (2005) 1313-1323
25. Fischer M., Barkley R.A., Edelbrock C.S., and Smallish L. The adolescent outcome of hyperactive children diagnosed by research criteria: II. Academic, attentional, and neuropsychological status. Journal of Consulting and Clinical Psychology 58 (1990) 580-588
26. Gaub M., and Carlson C.L. Gender differences in ADHD: A meta-analysis and critical review. Journal of the American Academy of Child and Adolescent Psychiatry 36 (1997) 1036-1045
27. Gjone H., Stevenson J., and Sundet J.M. Genetic influences on parent-reported attention-related problems in a Norwegian general population twin sample. Journal of the American Academy of Child and Adolescent Psychiatry 35 (1996) 588-596
28. Goldsmith H.H., Buss K.A., and Lemery K.S. Toddler and childhood temperament: Expanded content, stronger genetic evidence, new evidence for the importance of environment. Developmental Psychology 33 (1997) 891-905
29. Groot A.S., de Sonneville L.M.J., Stins J.F., and Boomsma D.I. Familial influences on sustained attention and inhibition in preschoolers. Journal of Child Psychology and Psychiatry 45 (2004) 306-314
30. Hay D.A., Bennett K.S., Levy F., Sergeant J., and Swanson J. A twin study of attention deficit/hyperactivity disorder dimensions rated by the Strengths and Weaknesses of ADHD-Symptoms and Normal Behavior (SWAN) Scale. Biological Psychiatry 61 (2007) 700-705
31. Hay D.A., Bennett K.S., McStephen M., Rooney R., and Levy F. Attention deficit hyperactivity disorder in twins: A developmental genetic analysis. Australian Journal of Psychology 56 (2004) 99-107
32. Hudziak J.J., Althoff R.R., Derks E.M., Faraone S.V., and Boomsma D.I. Prevalence and genetic architecture of Child Behavior Checklist-Juvenile Bipolar Disorder. Biological Psychiatry 58 (2005) 562-568
33. Hudziak J.J., Rudiger L.P., Neale M.C., Heath A., and Todd R.D. A twin study of inattentive, aggressive, and anxious/depressed behaviors. Journal of the American Academy of Child and Adolescent Psychiatry 39 (2000) 469-476
34. Jensen P.S., Hinshaw S.P., Kraemer H.C., Lenora N., Necworn J.H., Abikoff H.B., and Vitiello B. ADHD comorbidity findings from the MTA study: Comparing comorbid subgroups. Journal of the American Academy of Child and Adolescent Psychiatry 40 (2001) 147-158
35. Johnson W., McGue M., and Iacono W.G. Disruptive behavior and school grades: Genetic and environmental relations in 11-year-olds. Journal of Educational Psychology 97 (2005) 391-405
36. Kuntsi J., Gayan J., and Stevenson J. Parents' and teachers' ratings of problem behaviors in children: Genetic and contrast effects. Twin Research 3 (2000) 251-258
37. Kuo P., Lin C.C.H., Yang H., Soong W., and Chen W.J. A twin study of competence and behavioral/emotional problems among adolescents in Taiwan. Behavior Genetics 34 (2004) 63-74
38. Lahey B.B., Pelham W.E., Loney J., Lee S.S., and Willcutt E.G. Instability of the DSM-IV subtypes of ADHD from preschool through elementary school. Archives of General Psychiatry 62 (2005) 896-902
39. Lahey B.B., Rathouz P.J., Van Hulle C., Urbano R.C., Krueger R.F., Applegate B., and Waldman I.D. Testing structural models of DSM-IV symptoms of common forms of child and adolescent psychopathology. Journal of Abnormal Child Psychology 36 (2008) 187-206
40. Larsson H., Lichtenstein P., and Larsson J. Genetic contributions to the development of ADHD subtypes from childhood to adolescence. Journal of the American Academy of Child and Adolescent Psychiatry 45 (2006) 973-981
41. Maedgen J.W., and Carlson C.L. Social functioning and emotional regulation in the attention deficit hyperactivity disorder subtypes. Journal of Clinical Child Psychology 29 (2000) 30-42
42. Markon K.E., and Krueger R.F. An empirical comparison of information-theoretic model selection criteria. Behavior Genetics 34 (2004) 593-610
43. Martel M.M., Gobrogge K.L., Breedlove S.M., and Nigg J.T. Masculinized finger-length ratios of boys, but not girls, are associated with attention-deficit/hyperactivity disorder. Behavioral Neuroscience 122 (2008) 273-281
44. Martel M.M., and Nigg J.T. Child ADHD and personality/temperament traits of reactive and effortful control, resiliency, and emotionality. Journal of Child Psychology and Psychiatry 47 (2006) 1175-1183
45. Martin N.C., Eaves L.J., Kearsey M.J., and Davies P. The power of the classical twin study. Heredity 40 (1978) 97-116
46. Martin N.C., Levy F., Pieka J., and Hay D. A genetic study of attention deficit hyperactivity disorder, conduct disorder, oppositional defiant disorder, and reading disorder: Aetiological overlaps and implications. International Journal of Disability, Development, and Education 53 (2006) 21-34
47. Martin N., Scourfield J., and McGuffin P. Observer effects and heritability of attention deficit hyperactivity disorder symptoms. British Journal of Psychiatry 180 (2002) 260-265
48. McGue M., Keyes M., Sharma A., Elkins I., Legrand L., Johnson W., and Iacono W.G. The environment of adopted and non-adopted youth: Evidence of range restriction from the Sibling Interaction and Behavior Study (SIBS). Behavioral Genetics 37 (2007) 449-462
49. McLoughlin G., Ronald A., Kuntsi J., Asherson P., and Plomin R. Genetic support for the dual nature of attention-deficit hyperactivity disorder: Substantial genetic overlap between the inattentive and hyperactive-impulsive components. Journal of Abnormal Child Psychology 35 (2007) 999-1008
50. Milich R., Ballentine A.C., and Lynam D.R. ADHD/combined type and ADHD predominately inattentive type are distinct and unrelated disorders. Clinical Psychology: Science and Practice 8 (2001) 463-488
51. Nadder T.S., Rutter M., Silberg J.L., Maes H.H., and Eaves L.J. Genetic effects on the variation and covariation of attention-deficit hyperactivity disorder (ADHD) and oppositional defiant/conduct disorder (ODD/CD) symptomatologies across informant and occasion of measurement. Psychological Medicine 32 (2002) 39-53
52. Nadder T.S., Silberg J.L., Rutter M., Maes H.H., and Eaves L.J. Comparison of multiple measures of ADHD symptomatology: A multivariate genetic analysis. Journal of Child Psychology and Psychiatry 42 (2001) 475-486
53. Neale M.C. Mx: Statistical modeling (4th ed.) (1997) Department of Psychiatry, Virginia Commonwealth University, Richmond, VA
54. Neuman R.J., Heath A., Reich W., Bucholz K.K., Madden P.A.F., Sun L., and Todd R.D. Latent class analysis of ADHD and comorbid symptoms in a population sample of adolescent female twins. Journal of Child Psychology and Psychiatry 42 (2001) 933-942
55. Nigg J.T., Blaskey L., Huang-Pollock C.L., and Rappley M.D. Neuropsychological executive functions in DSM-IV ADHD subtypes. Journal of the American Academy of Child and Adolescent Psychiatry 26 (2002) 381-388
56. Plomin R., DeFries J.C., McClearn G.E., and McGruffin P. Behavioral genetics. Revised 5th ed. (2008), Worth Publishers and Freeman, New York, NY
57. Polderman T.J., Posthuma D., de Sonneville L.M., Verhulst F.C., and Boomsma D.I. Genetic analysis of teacher ratings of problem behavior in 5-year-old twins. Twin Research and Human Genetics 9 (2006) 122-130
58. Pulkkinen L., Kaprio J., and Rose R.J. Peers, teachers, and parents as the assessors of the behavioral and emotional problems of twins and their adjustment: The Multidimensional Peer Nomination Inventory. Twin Research 2 (1999) 274-285
59. Purcell S. Variance component models for gene-environment interaction in twin analysis. Twin Research 5 (2002) 554-571
60. Raftery A.E. Bayesian model selection in social research. Sociological Methodology 25 (1995) 111-163
61. Rapport M.D., Bolden J., Kofler M.J., Sarver D.E., Raiker J.S., and Alderson R.M. Hyperactivity in boys with attention-deficit hyperactivity disorder (ADHD): A ubiquitous core symptom or manifestation of working memory deficits. Journal of Abnormal Child Psychology 37 (2009) 521-524
62. Rhee S., and Waldman I.D. Genetic and environmental influences on antisocial behavior: A meta-analysis of twin and adoption studies. Psychological Bulletin 128 (2002) 490-529
63. Rietveld M.J.H., Hudziak J.J., Bartels M., van Beijsterveldt C.E.M., and Boomsma D.I. Heritability of attention problems in children: Cross-sectional results from a study of twins age 3-12 years. American Journal of Medical Genetics, Part B: Neuropsychiatric Genetics 117B (2003) 102-113
64. Rietveld M.J.H., Hudziak J.J., Bartels M., van Beijsterveldt C.E.M., and Boomsma D.I. Heritability of attention problems in children: Longitudinal results from a study of twins age 3 to 12. Journal of Child Psychology and Psychiatry 45 (2004) 577-588
65. Saudino K.J., Ronald A., and Plomin R. The etiology of behavior problems in 7-year-old twins: Substantial genetic influence and negligible shared environmental influence for parent ratings and ratings by same and different teachers. Journal of Abnormal Child Psychology 33 (2005) 113-130
66. Schmitz M., Cadore L., Paczko M., Kipper L., Chaves M., Rohde L.A., and Knijnik M. Neuropsychological performance in DSM-IV ADHD subtypes: An exploratory study with untreated adolescents. Canadian Journal of Psychiatry 47 (2002) 863-869
67. Sherman D.K., Iacono W.G., and McGue M.K. Attention-deficit hyperactivity disorder dimensions: A twin study of inattention and impulsivity-hyperactivity. Journal of the American Academy of Child and Adolescent Psychiatry 36 (1997) 745-753
68. Silberg J., Rutter M., Meyer J., Maes H., Hewitt J., Simonoff E., and Eaves L. Genetic and environmental influences on the covariation between hyperactivity and conduct disturbance in juvenile twins. Journal of Child Psychology and Psychiatry 37 (1996) 803-816
69. Simonoff E., Pickles A., Hervas A., Silberg J.L., Rutter M., and Eaves L. Genetic influences on childhood hyperactivity: Contrast effects imply parental rating bias, not sibling interaction. Psychological Medicine 28 (1998) 825-837
70. Smalley S.L., McGough J.J., Del'Homme M., New-Delman J., Gordon E., Kim T., and McCracken J.T. Familial clustering of symptoms and disruptive behaviors in multiplex families with attention-deficit/hyperactivity disorder. Journal of the American Academy of Child and Adolescent Psychiatry 39 (2000) 1135-1143
71. Sonuga-Barke E.J.S. The dual pathway model of AD/HD: An elaboration of neurodevelopmental characteristics. Neuroscience and Biobehavioral Reviews 27 (2003) 593-604
72. Sonuga-Barke E.J.S. Causal models of attention-deficit/hyperactivity disorder: From common simple deficits to multiple developmental pathways. Biological Psychiatry 57 (2005) 1231-1238
73. Stawicki J., Nigg J.T., and von Eye A. Family psychiatric history evidence on the nosological relations of DSM-IV ADHD subtypes combined and inattentive subtypes: New data and meta-analysis. Journal of Child Psychology and Psychiatry 47 (2006) 935-945
74. Thapar A., Harrington R., Ross K., and McGuffin P. Does definition of ADHD affect heritability?. Journal of the American Academy of Child and Adolescent Psychiatry 39 (2000) 1528-1536
75. Todd R.D., Rasmussen E.R., Neuman R.J., Reich W., Hudziak J.J., Bucholz K.K., and Heath A. Familiality and heritability of subtypes of attention deficit hyperactivity disorder in a population sample of adolescent female twins. American Journal of Psychiatry 158 (2001) 1891-1898
76. van Beijsterveldt C.E.M., Verhulst F.C., Molenaar P.C.M., and Boomsma D.I. The genetic basis of problem behavior in 5-year-old Dutch twin pairs. Behavior Genetics 34 (2004) 229-242
77. van den Oord E.J., Boomsma D.I., and Verhulst F.C. A study of problem behaviors in 10-15 year old biologically related and unrelated international adoptees. Behavior Genetics 24 (1994) 193-205
78. van den Oord E.J.C.G., Verhulst F.C., and Boomsma D.I. A genetic study of maternal and paternal ratings of problem behaviors in 3-year-old twins. Journal of Abnormal Psychology 105 (1996) 349-357
79. van den Oord E.J.C.G., Boomsma D.I., and Verhulst F.C. A study of genetic and environmental effects on the co-occurrence of problem behaviors in three-year-old twins. Journal of Abnormal Psychology 109 (2000) 360-372
80. van der Valk J.C., Verhulst F.C., Neale M.C., and Boomsma D.I. Longitudinal genetic analysis of problem behaviors in biologically related and unrelated adoptees. Behavior Genetics 28 (1998) 365-380
81. Willcutt E.G., Pennington B.F., and DeFries J.C. Etiology of inattention and hyperactivity/impulsivity in a community sample of twins with learning difficulties. Journal of Abnormal Child Psychology 28 (2000) 149-159
82. Willerman L. Activity level and hyperactivity in twins. Child Development 44 (1973) 288-293