Efficient production of multi-modified pigs for xenotransplantation by 'combineering', gene stacking and gene editing

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Fischer, Konrad ^a   Kraner Scheiber, Simone ^a   Petersen, Björn ^b   Rieblinger, Beate ^a   Buermann, Anna ^c   Flisikowska, Tatiana ^a   Flisikowski, Krzysztof ^a   Christan, Susanne ^a   Edlinger, Marlene ^a   Baars, Wiebke ^c   Kurome, Mayuko ^d   Zakhartchenko, Valeri ^d   Kessler, Barbara ^d   Plotzki, Elena ^e   Szczerbal, Izabela ^f   Switonski, Marek ^f   Denner, Joachim ^e   Wolf, Eckhard ^d   Schwinzer, Reinhard ^c   Niemann, Heiner ^b   Kind, Alexander ^a   Schnieke, Angelika ^a   more..

^a TECHNICAL UNIVERSITY OF MUNICH   (Germany)

^b Institute of Farm Animal Genetics   (Germany)

^c HANNOVER MEDICAL SCHOOL   (Germany)

^d UNIVERSITY OF MUNICH   (Germany)

^e ROBERT KOCH INSTITUTE   (Germany)

^f POZNA UNIVERSITY OF LIFE SCIENCES   (Poland)

Author keywords

[No Author keywords available]

Indexed keywords

COMPLEMENT;

ANIMAL; CRISPR CAS SYSTEM; GENE EDITING; GENETICS; GRAFT REJECTION; HUMAN; IMMUNOLOGY; PIG; PROCEDURES; TRANSGENIC ANIMAL; XENOGRAFT;

ANIMALS; ANIMALS, GENETICALLY MODIFIED; COMPLEMENT SYSTEM PROTEINS; CRISPR-CAS SYSTEMS; GENE EDITING; GRAFT REJECTION; HETEROGRAFTS; HUMANS; SWINE; TRANSPLANTATION, HETEROLOGOUS;

EID: 84976618019     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep29081     Document Type: Article

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