Comparative genome-scale modelling of Staphylococcus aureus strains identifies strain-specific metabolic capabilities linked to pathogenicity

Proceedings of the National Academy of Sciences of the United States of America

Volumn 113, Issue 26, 2016, Pages E3801-E3809

  Bosi, Emanuele ^a   Monk, Jonathan M ^b   Aziz, Ramy K ^c   Fondi, Marco ^a   Nizet, Victor ^d,e   Palsson, Bernhard Ø ^a,d  

^a UNIVERSITY OF FLORENCE   (Italy)

^b UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^c CAIRO UNIVERSITY   (Egypt)

^d UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

^e UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

Core genome; Mathematical modeling; Pangenome; Pathogenicity; Systems biology

Indexed keywords

AMINO ACID; CYSTEINE; GUANOSINE; LEUCINE; METHIONINE; NICOTINIC ACID; RIBOFLAVIN; THIAMINE; VIRULENCE FACTOR;

ANTIBIOTIC RESISTANCE; ARTICLE; AUXOTROPHY; BACTERIAL GENOME; BACTERIAL STRAIN; BACTERIAL VIRULENCE; ECOLOGICAL NICHE; GENE SEQUENCE; HUMAN; METAGENOMICS; NONHUMAN; NUCLEOTIDE METABOLISM; PRIORITY JOURNAL; STAPHYLOCOCCUS AUREUS; COMPARATIVE STUDY; GENETICS; GROWTH, DEVELOPMENT AND AGING; METABOLISM; MOLECULAR MODEL; PATHOGENICITY; SPECIES DIFFERENCE;

GENOME, BACTERIAL; MODELS, MOLECULAR; SPECIES SPECIFICITY; STAPHYLOCOCCUS AUREUS; VIRULENCE FACTORS;

EID: 84976481496     PISSN: 00278424     EISSN: 10916490     Source Type: Journal    
DOI: 10.1073/pnas.1523199113     Document Type: Article

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