Redundant Gs-coupled serotonin receptors regulate amyloid-β metabolism in vivo

Molecular Neurodegeneration

Volumn 11, Issue 1, 2016, Pages

  Fisher, Jonathan R ^a   Wallace, Clare E ^a   Tripoli, Danielle L ^a   Sheline, Yvette I ^b   Cirrito, John R ^a,c  

^a WASHINGTON UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b UNIVERSITY OF PENNSYLVANIA   (United States)

^c WASHINGTON UNIVERSITY   (United States)

Author keywords

Alzheimer's Disease; beta amyloid; Microdialysis; PKA; Serotonin receptor; SSRI; secretase

Indexed keywords

1 METHYL 3 INDOLECARBOXYLIC ACID [1 [2 (METHYLSULFONYLAMINO)ETHYL] 4 PIPERIDINYLMETHYL] ESTER; 3,N DIMETHYL N [1 METHYL 3 (4 METHYL 1 PIPERIDINYL)PROPYL]BENZENESULFONAMIDE; 8,9 DICHLORO 2,3,4,4A TETRAHYDRO 1H PYRAZINO[1,2 A]QUINOXALIN 5(6H) ONE; ALPHA SECRETASE; AMYLOID BETA PROTEIN; AS 19; CITALOPRAM; CYCLIC AMP DEPENDENT PROTEIN KINASE; GS COUPLED SEROTONIN RECEPTOR; IPSAPIRONE; KT 5720; ML 10302; PKI 14 22; SEROTONIN 4 RECEPTOR; SEROTONIN 6 RECEPTOR; SEROTONIN 7 RECEPTOR; SEROTONIN AGONIST; SEROTONIN RECEPTOR; ST 1936; UNCLASSIFIED DRUG; AMYLOID PROTEIN; SECRETASE; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN;

ADULT; ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; CYTOPLASM; ENZYME ACTIVITY; ENZYME INHIBITION; GENE EXPRESSION; IC50; IN VIVO STUDY; INTERSTITIAL FLUID; MOUSE; NONHUMAN; PROTEIN BLOOD LEVEL; PROTEIN FUNCTION; PROTEIN METABOLISM; SIGNAL TRANSDUCTION; AMYLOID PLAQUE; ANIMAL; DISEASE MODEL; METABOLISM; MICRODIALYSIS; PATHOLOGY; PROCEDURES;

ALZHEIMER DISEASE; AMYLOID PRECURSOR PROTEIN SECRETASES; AMYLOIDOGENIC PROTEINS; ANIMALS; DISEASE MODELS, ANIMAL; GTP-BINDING PROTEIN ALPHA SUBUNITS, GS; MICE; MICRODIALYSIS; PLAQUE, AMYLOID; RECEPTORS, SEROTONIN;

EID: 84975810729     PISSN: None     EISSN: 17501326     Source Type: Journal    
DOI: 10.1186/s13024-016-0112-5     Document Type: Article

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