Analysis of region-specific changes in gene expression upon treatment with citalopram and desipramine reveals temporal dynamics in response to antidepressant drugs at the transcriptome level

Psychopharmacology

Volumn 223, Issue 3, 2012, Pages 281-297

  Gaska, Magdalena ^a   Kusmider, Maciej ^a   Solich, Joanna ^a   Faron Górecka, Agata ^a   Krawczyk, Malgorzata J ^b   Kulakowski, Krzysztof ^b   Dziedzicka Wasylewska, Marta ^a  

^a INSTITUTE OF PHARMACOLOGY   (Poland)

^b AGH UNIVERSITY OF SCIENCE AND TECHNOLOGY   (Poland)

Author keywords

Antidepressant; Citalopram; Delayed onset of action; Desipramine; Gene expression; In situ hybridization; Rats; RT PCR; Timecourse

Indexed keywords

CITALOPRAM; DESIPRAMINE; SERUM RESPONSE FACTOR; TRANSCRIPTION FACTOR; TRANSCRIPTOME;

AMYGDALOID NUCLEUS; ANIMAL TISSUE; ARTICLE; BINDING SITE; CINGULATE GYRUS; CONTROLLED STUDY; DECOMPOSITION; DENTATE GYRUS; DRUG ACTIVITY; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE IDENTIFICATION; GENETIC ANALYSIS; HIPPOCAMPUS; IMMEDIATE EARLY GENE; IN SITU HYBRIDIZATION; MALE; MOLECULAR DYNAMICS; MULTIPLE CYCLE TREATMENT; NONHUMAN; PREFRONTAL CORTEX; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; QUANTITATIVE ANALYSIS; RAT; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TIME; TREATMENT DURATION;

ANALYSIS OF VARIANCE; ANIMALS; ANTIDEPRESSIVE AGENTS; BRAIN; BRAIN MAPPING; CITALOPRAM; DESIPRAMINE; GENE EXPRESSION; GENE EXPRESSION PROFILING; RATS; RATS, WISTAR; REAL-TIME POLYMERASE CHAIN REACTION; STRUCTURE-ACTIVITY RELATIONSHIP; TIME FACTORS;

EID: 84866729811     PISSN: 00333158     EISSN: 14322072     Source Type: Journal    
DOI: 10.1007/s00213-012-2714-0     Document Type: Article

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