Alterations in brain Protein Kinase A activity and reversal of morphine tolerance by two fragments of native Protein Kinase A inhibitor peptide (PKI)

Neuropharmacology

Volumn 48, Issue 5, 2005, Pages 648-657

  Dalton, George D ^a   Smith, Forrest L ^a   Smith, Paul A ^a   Dewey, William L ^a  

^a VIRGINIA COMMONWEALTH UNIVERSITY   (United States)

Author keywords

Antinociception; Morphine analgesia and tolerance; Mouse; Pain; Protein Kinase A; Protein Kinase A inhibitors

Indexed keywords

AMINO ACID DERIVATIVE; CYCLIC AMP DEPENDENT PROTEIN KINASE; CYCLIC AMP DEPENDENT PROTEIN KINASE INHIBITOR; MORPHINE; THREONYLTYROSYLALANYLASPARTYLPHENYLALANYLISOLEUCYLALANYLSERYLGLYCYLARGINYL THREONYLGLYCYLARGINYLARGINYLASPARAGINYLALANYLISOLEUCINAMIDE; UNCLASSIFIED DRUG;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BRAIN REGION; BRAIN VENTRICLE; COMPARATIVE STUDY; CONTROLLED STUDY; CYTOSOL; ENZYME ACTIVITY; LUMBAR SPINAL CORD; MALE; MEASUREMENT; MEDULLA OBLONGATA; MORPHINE TOLERANCE; MOUSE; NONHUMAN; PERIAQUEDUCTAL GRAY MATTER; PRIORITY JOURNAL; THALAMUS;

EID: 16244371732     PISSN: 00283908     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2004.12.006     Document Type: Article

References (30)

1. S.J. Beebe, and J.D. Corbin Cyclic-nucleotide-dependent protein kinases The Enzymes 17 1986 43 111
2. M.A. Bernstein, and S.P. Welch Effects of spinal versus supraspinal administration of cyclic nucleotide-dependent protein kinase inhibitors on morphine tolerance in mice Drug and Alcohol Dependence 44 1997 41 46
3. C.I. Bliss Statistics in biology 1967 McGraw-Hill New York pp. 439
4. M.M. Bradford A rapid and sensitive method for the quantification of microgram quantities of protein utilizing the principle of protein-dye binding Analytical Biochemistry 72 1976 248 254
5. B. Buzas, J. Rosenberger, and B.M. Cox Mu and delta opioid receptor gene expression after chronic treatment with opioid agonist Neuroreport 7 1996 1505 1508
6. M.P. Castelli, M. Melis, M. Mameli, P. Fadda, G. Diaz, and G.L. Gessa Chronic morphine and naltrexone fail to modify mu-opioid receptor mRNA levels in the rat brain Brain Research Molecular Brain Research 45 1997 149 153
7. D. Colquhoun Lectures in biostatistics: an introduction to statistics with applications in biology and medicine 1971 Clarendon Press London, Oxford pp. 327-332
8. J.G. Demaille, K.A. Peters, and E.H. Fischer Isolation and properties of the rabbit skeletal muscle protein inhibitor of adenosine 3′,5′- monophosphate dependent protein kinases Biochemistry 16 1977 3080 3086
9. D.B. Glass, H.C. Cheng, B.E. Kemp, and D.A. Walsh Differential and common recognition of the catalytic sites of the cGMP-dependent and cAMP-dependent protein kinases by inhibitory peptides derived from the heat-stable inhibitor protein Journal of Biological Chemistry 261 1986 12166 12171
10. D.B. Glass, H.C. Cheng, L. Mende-Mueller, J. Reed, and D.A. Walsh Primary structural determinants essential for potent inhibition of cAMP-dependent protein kinase by inhibitory peptides corresponding to the active portion of the heat-stable inhibitor protein Journal of Biological Chemistry 264 1989 8802 8810
11. D.B. Glass, L.J. Lundquist, B.M. Katz, and D.A. Walsh Protein kinase inhibitor-(6-22)-amide peptide analogs with standard and nonstandard amino acid substitutions for phenylalanine 10 Journal of Biological Chemistry 264 1989 14579 14584
12. L.S. Harris, and A.K. Pierson Some narcotic antagonists in the benzomorphan series Journal of Pharmacology and Experimental Therapeutics 143 1964 141 148
13. W.W. Kaelbar, C.L. Mitchell, A.J. Yormat, A.K. Afifi, and S.A. Lorens Centrum medianum-parafascicularis lesions and reactivity to noxious and non-noxious stimuli Experimental Neurology 46 1975 282 290
14. D.E. Keith, B. Anton, S.R. Murray, P.A. Zaki, P.C. Chu, D.V. Lissin, G. Monteillet-Agius, P.L. Stewart, C.J. Evans, and M. von Zastrow mu-Opioid receptor internalization: opiate drugs have differential effects on a conserved endocytic mechanism in vitro and in the mammalian brain Molecular Pharmacology 53 1998 377 384
15. P.Y. Law, L.J. Erickson, R. El-Kouhen, L. Dicker, J. Solberg, W. Wang, E. Miller, A.L. Burd, and H.H. Loh Receptor density and recycling affect the rate of agonist-induced desensitization of mu-opioid receptor Molecular Pharmacology 58 2000 388 398
16. E.J. Nestler, and J.F. Tallman Chronic morphine treatment increases cyclic AMP-dependent protein kinase a activity in the rat locus coeruleus Molecular Pharmacology 33 1988 127 132
17. G. Paxinos, and K.B.J. Franklin The mouse brain in stereotaxic coordinates 2000 Academic Press San Diego
18. N.W. Pedigo, W.L. Dewey, and L.S. Harris Determination and characterization of the antinociceptive activity of intraventricularly administered acetylcholine in mice Journal of Pharmacology and Experimental Therapeutics 193 1975 845 852
19. M. Satoh, A. Kubota, T. Iwama, T. Wada, M. Yasui, K. Fujibayashi, and H. Takagi Comparison of analgesic potencies of mu, delta, kappa agonists locally applied to various CNS regions relevant to analgesia in rats Life Sciences 33 1983 689 692
20. J. Scott, E.H. Fischer, J.G. Demaille, and E.G. Krebs Identification of an inhibitory region of the heat-stable protein inhibitor of the cAMP-dependent protein kinase Proceedings of the National Academy of Sciences, USA 82 1985 4379 4382
21. J.D. Scott, M.B. Glaccum, E.H. Fischer, and E.G. Krebs Primary-structure requirements for inhibition by the heat-stable inhibitor of the cAMP-dependent protein kinase Proceedings of the National Academy of Sciences, USA 83 1986 1613 1616
22. J. Shen, A.B. Gomes, K. Gallagher, K. Stafford, and B.C. Yoburn Role of cAMP-dependent protein kinase (PKA) in opioid agonist-induced mu-opioid receptor downregulation and tolerance in mice Synapse 38 2000 322 327
23. F.L. Smith, R.R. Javed, M.J. Elzey, and W.L. Dewey The expression of a high level of morphine antinociceptive tolerance in mice involves both PKC and PKA Brain Research 985 2003 78 88
24. R.J. Tallarida, and R.B. Murray Manual of pharmacologic calculations, procedure 8, graded dose-responses 1987 Springer-Verlag New York, NY pp. 26-31
25. K. Tasken, and E.M. Aandahl Localized effects of cAMP mediated by distinct routes of protein kinase A Physiology Reviews 84 2004 137 167
26. R.Z. Terwilliger, D. Beitner-Johnson, K.A. Sevarino, S.M. Crain, and E.J. Nestler A general role for adaptations in G-proteins and the cyclic AMP system in mediating the chronic actions of morphine and cocaine on neuronal function Brain Research 548 1991 100 110
27. 2- dependent interaction of the inhibitor protein of the cAMP-dependent protein kinase with the catalytic subunit Journal of Biological Chemistry 258 1983 3682 3692
28. T.L. Yaksh Pharmacology and mechanisms of opioid analgesic activity Acta Anaesthesiologica Scandinavica 41 1997 94 111
29. B.C. Yoburn, B. Billings, and A. Duttaroy Opioid receptor regulation in mice Journal of Pharmacology and Experimental Therapeutics 265 1993 314 320
30. J. Zhang, S.S. Ferguson, L.S. Barak, S.R. Bodduluri, S.A. Laporte, P.Y. Law, and M.G. Caron Role for G-protein-coupled receptor kinase in agonist-specific regulation of mu-opioid receptor responsiveness Proceedings of the National Academy of Sciences, USA 95 1998 7157 7162