Function-specific virtual screening for GPCR ligands using a combined scoring method

Scientific Reports

Volumn 6, Issue , 2016, Pages

  Kooistra, Albert J ^a   Vischer, Henry F ^a   McNaught Flores, Daniel ^a   Leurs, Rob ^a   De Esch, Iwan J P ^a   De Graaf, Chris ^a  

^a AMSTERDAM INSTITUTE FOR MOLECULES   (Netherlands)

Author keywords

[No Author keywords available]

Indexed keywords

BETA ADRENERGIC RECEPTOR; BETA ADRENERGIC RECEPTOR BLOCKING AGENT; BETA ADRENERGIC RECEPTOR STIMULATING AGENT; G PROTEIN COUPLED RECEPTOR; HISTAMINE AGONIST; HISTAMINE H1 RECEPTOR; HISTAMINE H1 RECEPTOR ANTAGONIST; LIGAND; PROTEIN BINDING; RECOMBINANT PROTEIN;

BINDING SITE; CHEMISTRY; COMPUTER INTERFACE; COMPUTER SIMULATION; DRUG DEVELOPMENT; GENETICS; HEK293 CELL LINE; HUMAN; METABOLISM; MOLECULAR DOCKING; MOLECULAR MODEL; PRECLINICAL STUDY; PROCEDURES; RADIOASSAY; X RAY CRYSTALLOGRAPHY;

ADRENERGIC BETA-AGONISTS; ADRENERGIC BETA-ANTAGONISTS; BINDING SITES; COMPUTER SIMULATION; CRYSTALLOGRAPHY, X-RAY; DRUG DISCOVERY; DRUG EVALUATION, PRECLINICAL; HEK293 CELLS; HISTAMINE AGONISTS; HISTAMINE H1 ANTAGONISTS; HUMANS; LIGANDS; MODELS, MOLECULAR; MOLECULAR DOCKING SIMULATION; PROTEIN BINDING; RADIOLIGAND ASSAY; RECEPTORS, ADRENERGIC, BETA; RECEPTORS, G-PROTEIN-COUPLED; RECEPTORS, HISTAMINE H1; RECOMBINANT PROTEINS; USER-COMPUTER INTERFACE;

EID: 84975721733     PISSN: None     EISSN: 20452322     Source Type: Journal    
DOI: 10.1038/srep28288     Document Type: Article

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