G-protein coupled receptors: Advances in simulation and drug discovery

Current Opinion in Structural Biology

Volumn 41, Issue , 2016, Pages 83-89

  Miao, Yinglong ^a,b   McCammon, J Andrew ^a,b  

^a HOWARD HUGHES MEDICAL INSTITUTE   (United States)

^b UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

G PROTEIN COUPLED RECEPTOR; GQ PROTEIN; GUANINE NUCLEOTIDE BINDING PROTEIN; INHIBITORY GUANINE NUCLEOTIDE BINDING PROTEIN; RETINA S ANTIGEN; STIMULATORY GUANINE NUCLEOTIDE BINDING PROTEIN; UNCLASSIFIED DRUG; LIGAND;

ACCELERATED MOLECULAR DYNAMICS; COMPUTER AIDED DESIGN; CONFORMATIONAL TRANSITION; INTRACELLULAR SIGNALING; LIGAND BINDING; LONG TIMESCAL CONVENTIONAL MOLECULAR DYNAMICS; MARKOV STATE MODEL; METADYNAMICS; OLIGOMERIZATION; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; RANDOM ACCELERATION MOLECULAR DYNAMICS; REVIEW; SIMULATION; STEERED MOLECULAR DYNAMICS; CHEMISTRY; DRUG DEVELOPMENT; HUMAN; METABOLISM; MOLECULAR DYNAMICS; PROCEDURES;

COMPUTER-AIDED DESIGN; DRUG DISCOVERY; HUMANS; LIGANDS; MOLECULAR DYNAMICS SIMULATION; RECEPTORS, G-PROTEIN-COUPLED;

EID: 84975518316     PISSN: 0959440X     EISSN: 1879033X     Source Type: Journal    
DOI: 10.1016/j.sbi.2016.06.008     Document Type: Review

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