P53-dependent upregulation of neutral sphingomyelinase-2: Role in doxorubicin-induced growth arrest

Cell Death and Disease

Volumn 6, Issue 10, 2015, Pages

  Shamseddine, Aa ^a   Clarke, Cj ^a   Carroll, B ^a   Airola, M V ^a   Mohammed, S ^a   Rella, A ^b   Obeid, Lm ^c   Hannun, Ya ^a,b,d  

^a STONY BROOK UNIVERSITY   (United States)

^b Stony Brook Medicine   (United States)

^c STONY BROOK UNIVERSITY   (United States)

^d Northport Veterans Affairs Hospital   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ATAXIA TELANGIACTESIA RELATED PROTEIN; CERAMIDE; CHECKPOINT KINASE 1; DOXORUBICIN; MESSENGER RNA; NEUTRAL SPHINGOMYELINASE 2; PROTEIN; PROTEIN P53; SMALL INTERFERING RNA; SPHINGOMYELIN; SPHINGOMYELIN PHOSPHODIESTERASE; UNCLASSIFIED DRUG; SMPD3 PROTEIN, HUMAN;

ANIMAL TISSUE; ARTICLE; BREAST CANCER; CONTROLLED STUDY; DNA BINDING; DNA DAMAGE; DOXORUBICIN INDUCED GROWTH ARREST; ENZYME ACTIVITY; GENE OVEREXPRESSION; GENE SILENCING; GENE TARGETING; GROWTH DISORDER; HUMAN; IN VITRO STUDY; NONHUMAN; PIG; PRIORITY JOURNAL; PROTEIN ACETYLATION; QUANTITATIVE ANALYSIS; REAL TIME POLYMERASE CHAIN REACTION; TRANSCRIPTION INITIATION; TRANSCRIPTION INITIATION SITE; TRANSCRIPTION REGULATION; UPREGULATION; DRUG EFFECTS; GENE EXPRESSION REGULATION; GENETICS; MCF-7 CELL LINE; METABOLISM; PHYSIOLOGY;

DNA DAMAGE; DOXORUBICIN; GENE EXPRESSION REGULATION; GENE KNOCKDOWN TECHNIQUES; HUMANS; MCF-7 CELLS; RNA, MESSENGER; SPHINGOMYELIN PHOSPHODIESTERASE; TUMOR SUPPRESSOR PROTEIN P53; UP-REGULATION;

EID: 84975321398     PISSN: None     EISSN: 20414889     Source Type: Journal    
DOI: 10.1038/cddis.2015.268     Document Type: Article

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