Transcriptional regulation of neutral sphingomyelinase 2 in all-trans retinoic acid-treated human breast cancer cell line, MCF-7

Journal of Biochemistry

Volumn 151, Issue 6, 2012, Pages 599-610

  Ito, Hiromi ^a   Tanaka, Kouji ^b   Hagiwara, Kazumi ^c   Kobayashi, Misa ^c   Hoshikawa, Asuka ^c   Mizutani, Naoki ^c   Takagi, Akira ^a   Kojima, Tetsuhito ^a   Sobue, Sayaka ^d   Ichihara, Masatoshi ^d   Suzuki, Motoshi ^c   Tamiya Koizumi, Keiko ^a   Nakamura, Mitsuhiro ^e   Banno, Yoshiko ^f   Nozawa, Yoshinori ^g   Murate, Takashi ^a  

^a NAGOYA UNIVERSITY   (Japan)

^b NAGOYA CITY UNIVERSITY   (Japan)

^c NAGOYA UNIVERSITY GRADUATE SCHOOL OF MEDICINE   (Japan)

^d CHUBU UNIVERSITY   (Japan)

^e GIFU PHARMACEUTICAL UNIVERSITY   (Japan)

^f GIFU UNIVERSITY   (Japan)

^g TOKAI GAKUEN UNIVERSITY   (Japan)

Author keywords

all trans retinoic acid; chromatin remodelling; MCF 7 cell; neutral sphingomyelinase 2; promoter analysis

Indexed keywords

ESTROGEN RECEPTOR ALPHA; HISTONE H3; MESSENGER RNA; MITHRAMYCIN A; NEUTRAL SPHINGOMYELINASE 2; PROTEIN KINASE C DELTA; RETINOIC ACID; RETINOID X RECEPTOR ALPHA; SPHINGOMYELIN PHOSPHODIESTERASE; SPHINGOMYELIN PHOSPHODIESTERASE INHIBITOR; TRANSCRIPTION FACTOR SP1; TRANSCRIPTION FACTOR SP3; UNCLASSIFIED DRUG;

ARTICLE; BREAST CANCER; CELL STRAIN MCF 7; CHROMATIN IMMUNOPRECIPITATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; GEL MOBILITY SHIFT ASSAY; HISTONE ACETYLATION; HUMAN; HUMAN CELL; IN VITRO STUDY; PROMOTER REGION; PROTEIN EXPRESSION; TRANSCRIPTION REGULATION; WESTERN BLOTTING;

CELL SURVIVAL; GENE EXPRESSION PROFILING; HUMANS; MCF-7 CELLS; RNA, MESSENGER; SPHINGOMYELIN PHOSPHODIESTERASE; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSCRIPTION, GENETIC; TRETINOIN;

EID: 84862275718     PISSN: 0021924X     EISSN: 17562651     Source Type: Journal    
DOI: 10.1093/jb/mvs037     Document Type: Article

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