Evaluating the neurotherapeutic potential of a water-soluble progesterone analog after traumatic brain injury in rats

Neuropharmacology

Volumn 109, Issue , 2016, Pages 148-158

  Wali, Bushra ^a   Sayeed, Iqbal ^a   Guthrie, David B ^b   Natchus, Michael G ^b   Turan, Nefize ^a   Liotta, Dennis C ^b   Stein, Donald G ^a  

^a EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b EMORY UNIVERSITY   (United States)

Author keywords

Edema; Neurosteroid; Progesterone; Progesterone analogs; Traumatic brain injury

Indexed keywords

EIDD 1723; PROGESTERONE; PROGESTERONE DERIVATIVE; UNCLASSIFIED DRUG; NEUROPROTECTIVE AGENT; WATER;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTROCYTOSIS; BLOOD BRAIN BARRIER; BRAIN EDEMA; CONTROLLED STUDY; DRUG ELIMINATION; DRUG STRUCTURE; FUNCTIONAL ASSESSMENT; GRIP STRENGTH; LATENT PERIOD; MALE; NONHUMAN; OUTCOME ASSESSMENT; PRIORITY JOURNAL; RAT; SPATIAL LEARNING; TASK PERFORMANCE; TRAUMATIC BRAIN INJURY; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN INJURIES, TRAUMATIC; CHEMISTRY; DOSE RESPONSE; DRUG FORMULATION; METABOLISM; PATHOLOGY; PRECLINICAL STUDY; PROCEDURES; RANDOMIZATION; SOLUBILITY; SPRAGUE DAWLEY RAT;

ANIMALS; BRAIN INJURIES, TRAUMATIC; DOSE-RESPONSE RELATIONSHIP, DRUG; DRUG COMPOUNDING; DRUG EVALUATION, PRECLINICAL; MALE; NEUROPROTECTIVE AGENTS; PROGESTERONE; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY; WATER;

EID: 84975126840     PISSN: 00283908     EISSN: 18737064     Source Type: Journal    
DOI: 10.1016/j.neuropharm.2016.05.017     Document Type: Article

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