메뉴 건너뛰기




Volumn 1008, Issue 1, 2004, Pages 29-39

Effects of progesterone on the inflammatory response to brain injury in the rat

Author keywords

Astrocyte; Disorders of the nervous system; Edema; Microglia; Neuronal survival; Progesterone; Trauma; Traumatic brain injury

Indexed keywords

NEUROPROTECTIVE AGENT; PROGESTERONE;

EID: 1842664453     PISSN: 00068993     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.brainres.2004.02.022     Document Type: Article
Times cited : (103)

References (64)
  • 2
    • 0032401798 scopus 로고    scopus 로고
    • Progesterone facilitates the acquisition of avoidance learning and protects against subcortical neuronal death following prefrontal cortex ablation in the rat
    • Asbury E.T., Fritts M.E., Horton J.E., Isaac W.L. Progesterone facilitates the acquisition of avoidance learning and protects against subcortical neuronal death following prefrontal cortex ablation in the rat. Behav. Brain Res. 97:1998;99-106.
    • (1998) Behav. Brain Res. , vol.97 , pp. 99-106
    • Asbury, E.T.1    Fritts, M.E.2    Horton, J.E.3    Isaac, W.L.4
  • 3
    • 0031947121 scopus 로고    scopus 로고
    • Astrocytes as mediators of immune and inflammatory responses in the CNS
    • Aschner M. Astrocytes as mediators of immune and inflammatory responses in the CNS. Neurotoxicology. 19:1998;269-281.
    • (1998) Neurotoxicology , vol.19 , pp. 269-281
    • Aschner, M.1
  • 6
    • 0027104247 scopus 로고
    • CNS glial scar tissue: A source of molecules which inhibit central neurite outgrowth
    • Boloventa B., Wandosell F., Nieto-Sampedro M. CNS glial scar tissue: a source of molecules which inhibit central neurite outgrowth. Prog. Brain Res. 94:1992;367-379.
    • (1992) Prog. Brain Res. , vol.94 , pp. 367-379
    • Boloventa, B.1    Wandosell, F.2    Nieto-Sampedro, M.3
  • 7
    • 0026463206 scopus 로고
    • The glial cell glutamate uptake carrier counter transports pH-changing anions
    • Bouvier M., Szatkowski M., Amato A., Attwell D. The glial cell glutamate uptake carrier counter transports pH-changing anions. Nature. 360:1992;470-474.
    • (1992) Nature , vol.360 , pp. 470-474
    • Bouvier, M.1    Szatkowski, M.2    Amato, A.3    Attwell, D.4
  • 8
    • 0033215009 scopus 로고    scopus 로고
    • Microglial-neuronal interactions in synaptic damage and recovery
    • Bruce-Keller A.J. Microglial-neuronal interactions in synaptic damage and recovery. J. Neurosci. Res. 58:1999;191-201.
    • (1999) J. Neurosci. Res. , vol.58 , pp. 191-201
    • Bruce-Keller, A.J.1
  • 9
    • 0030891491 scopus 로고    scopus 로고
    • Expression of endothelial adhesion molecules and recruitment of neutrophils after traumatic brain injury in rats
    • Carlos T.M., Clark R.S.B., Franicola-Higgins D., Schiding J.K., Kochanek P.M. Expression of endothelial adhesion molecules and recruitment of neutrophils after traumatic brain injury in rats. J. Leukoc. Biol. 61:1997;279-285.
    • (1997) J. Leukoc. Biol. , vol.61 , pp. 279-285
    • Carlos, T.M.1    Clark, R.S.B.2    Franicola-Higgins, D.3    Schiding, J.K.4    Kochanek, P.M.5
  • 10
    • 0036146341 scopus 로고    scopus 로고
    • Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus
    • Cervantes M., González-Vidal M.-D., Ruelas R., Escobar A., Moralí G. Neuroprotective effects of progesterone on damage elicited by acute global cerebral ischemia in neurons of the caudate nucleus. Arch. Med. Res. 33:2002;6-14.
    • (2002) Arch. Med. Res. , vol.33 , pp. 6-14
    • Cervantes, M.1    González-Vidal, M.-D.2    Ruelas, R.3    Escobar, A.4    Moralí, G.5
  • 11
    • 0025742725 scopus 로고
    • Traumatic brain injuries: Structural changes
    • Cervós-Navarro J., Lafuente J.V. Traumatic brain injuries: structural changes. J. Neurol. Sci. 103:1991;S3-S14.
    • (1991) J. Neurol. Sci. , vol.103 , pp. 3-S14
    • Cervós-Navarro, J.1    Lafuente, J.V.2
  • 12
    • 0026738695 scopus 로고
    • Activated microglia mediate neuronal cell injury via a nitric oxide mechanism
    • Chao C.C., Hu S., Molitor T.W., Shaskani E.G., Peterson P.K. Activated microglia mediate neuronal cell injury via a nitric oxide mechanism. J. Immunol. 8:1992;2736-2741.
    • (1992) J. Immunol. , vol.8 , pp. 2736-2741
    • Chao, C.C.1    Hu, S.2    Molitor, T.W.3    Shaskani, E.G.4    Peterson, P.K.5
  • 13
    • 0032724682 scopus 로고    scopus 로고
    • Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat
    • Chen J., Chopp M., Li Y. Neuroprotective effects of progesterone after transient middle cerebral artery occlusion in rat. J. Neurol. Sci. 171:1999;24-30.
    • (1999) J. Neurol. Sci. , vol.171 , pp. 24-30
    • Chen, J.1    Chopp, M.2    Li, Y.3
  • 14
    • 0026497926 scopus 로고
    • Excitotoxic cell death
    • Choi D.W. Excitotoxic cell death. J. Neurobiol. 23:1992;1261-1276.
    • (1992) J. Neurobiol. , vol.23 , pp. 1261-1276
    • Choi, D.W.1
  • 15
    • 0023642584 scopus 로고
    • Production of superoxide anions by a CNS macrophage, the microglia
    • Colton C.A., Gilbert D.L. Production of superoxide anions by a CNS macrophage, the microglia. FEBS Lett. 223:1987;284-288.
    • (1987) FEBS Lett. , vol.223 , pp. 284-288
    • Colton, C.A.1    Gilbert, D.L.2
  • 16
    • 0030027461 scopus 로고    scopus 로고
    • Methods for determining numbers of cells and synapses: A case for more uniform standards of review
    • Coogeshall R.E., Lekan H.A. Methods for determining numbers of cells and synapses: a case for more uniform standards of review. J. Comp. Neurol. 364:1996;6-15.
    • (1996) J. Comp. Neurol. , vol.364 , pp. 6-15
    • Coogeshall, R.E.1    Lekan, H.A.2
  • 18
    • 0021849021 scopus 로고
    • Glial fibrillary acidic protein (GFAP): The major protein of glial intermediate filaments in differentiated astrocytes
    • Eng L.F. Glial fibrillary acidic protein (GFAP): the major protein of glial intermediate filaments in differentiated astrocytes. J. Neuroimmunol. 8:1985;203-214.
    • (1985) J. Neuroimmunol. , vol.8 , pp. 203-214
    • Eng, L.F.1
  • 19
    • 0028675999 scopus 로고
    • Cytokines, inflammation and brain injury: Role of tumor necrosis factor-α
    • Feurstein G.Z., Liu T., Barone F.C. Cytokines, inflammation and brain injury: role of tumor necrosis factor-α Cerebrovasc. Brain Metab. Rev. 6:1994;341-360.
    • (1994) Cerebrovasc. Brain Metab. Rev. , vol.6 , pp. 341-360
    • Feurstein, G.Z.1    Liu, T.2    Barone, F.C.3
  • 20
    • 0031920259 scopus 로고    scopus 로고
    • Cellular dynamics of macrophages and microglial cells in reaction to stab wounds in rat cerebral cortex
    • Fujita T., Yoshimine T., Maruno M., Hayakawa T. Cellular dynamics of macrophages and microglial cells in reaction to stab wounds in rat cerebral cortex. Acta Neurochir. (Wien). 140:1998;275-279.
    • (1998) Acta Neurochir. (Wien) , vol.140 , pp. 275-279
    • Fujita, T.1    Yoshimine, T.2    Maruno, M.3    Hayakawa, T.4
  • 21
    • 0035727796 scopus 로고    scopus 로고
    • Effects of the duration of progesterone treatment on the resolution of cerebral edema induced by cortical contusions in rats
    • Galani R., Hoffman S.W., Stein D.G. Effects of the duration of progesterone treatment on the resolution of cerebral edema induced by cortical contusions in rats. Restor. Neurol. Neurosci. 18:2001;161-166.
    • (2001) Restor. Neurol. Neurosci. , vol.18 , pp. 161-166
    • Galani, R.1    Hoffman, S.W.2    Stein, D.G.3
  • 22
    • 0026486613 scopus 로고
    • Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures
    • Galea E., Feinstein D.L., Reis D.J. Induction of calcium-independent nitric oxide synthase activity in primary rat glial cultures. Proc. Natl. Acad. Sci. U.S.A. 89:1992;10945-10949.
    • (1992) Proc. Natl. Acad. Sci. U.S.A. , vol.89 , pp. 10945-10949
    • Galea, E.1    Feinstein, D.L.2    Reis, D.J.3
  • 24
    • 0027520373 scopus 로고
    • Gonadal hormones down-regulate reactive gliosis and astrocyte accumulation after a penetrating brain injury
    • Garcia-Estrada J., Del Rio J.A., Luquin S., Soraino E., Garcia-Segura L.M. Gonadal hormones down-regulate reactive gliosis and astrocyte accumulation after a penetrating brain injury. Brain Res. 628:1993;271-278.
    • (1993) Brain Res. , vol.628 , pp. 271-278
    • Garcia-Estrada, J.1    Del Rio, J.A.2    Luquin, S.3    Soraino, E.4    Garcia-Segura, L.M.5
  • 25
    • 0344492735 scopus 로고    scopus 로고
    • Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury
    • Garcia-Estrada J., Luquin S., Fernandez A.M., Garcia-Segura L.M. Dehydroepiandrosterone, pregnenolone and sex steroids down-regulate reactive astroglia in the male rat brain after a penetrating brain injury. Int. J. Dev. Neurosci. 17:1999;145-151.
    • (1999) Int. J. Dev. Neurosci. , vol.17 , pp. 145-151
    • Garcia-Estrada, J.1    Luquin, S.2    Fernandez, A.M.3    Garcia-Segura, L.M.4
  • 26
    • 0031887788 scopus 로고    scopus 로고
    • Inflammation in traumatic brain injury: Role of cytokines and chemokines
    • Ghrinkar R.S., Lee Y.L., Eng L.E. Inflammation in traumatic brain injury: role of cytokines and chemokines. Neurochem. Res. 23:1998;329-340.
    • (1998) Neurochem. Res. , vol.23 , pp. 329-340
    • Ghrinkar, R.S.1    Lee, Y.L.2    Eng, L.E.3
  • 27
    • 0021912473 scopus 로고
    • Interleukin-1 stimulation of astroglial accumulation after brain injury
    • Giulian D., Lachman L.B. Interleukin-1 stimulation of astroglial accumulation after brain injury. Science. 228:1985;497-499.
    • (1985) Science , vol.228 , pp. 497-499
    • Giulian, D.1    Lachman, L.B.2
  • 28
    • 0025058337 scopus 로고
    • Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord
    • Giulian D., Robertson C. Inhibition of mononuclear phagocytes reduces ischemic injury in the spinal cord. Ann. Neurol. 27:1990;33-42.
    • (1990) Ann. Neurol. , vol.27 , pp. 33-42
    • Giulian, D.1    Robertson, C.2
  • 29
    • 0022441440 scopus 로고
    • Interleukin 1 of the central nervous system is produced by ameboid microglia
    • Giulian D., Baker T.J., Shih L.-C.N., Lachman L.B. Interleukin 1 of the central nervous system is produced by ameboid microglia. J. Exp. Med. 164:1986;594-604.
    • (1986) J. Exp. Med. , vol.164 , pp. 594-604
    • Giulian, D.1    Baker, T.J.2    Shih, L.-C.N.3    Lachman, L.B.4
  • 30
    • 0142195893 scopus 로고    scopus 로고
    • Behavioral effect and anatomic correlates after brain injury: A progesterone dose-response study
    • Goss C.W., Hoffman S.W., Stein D.G. Behavioral effect and anatomic correlates after brain injury: a progesterone dose-response study. Pharmacol. Biochem. Behav. 76:2003;231-242.
    • (2003) Pharmacol. Biochem. Behav. , vol.76 , pp. 231-242
    • Goss, C.W.1    Hoffman, S.W.2    Stein, D.G.3
  • 31
    • 33644993291 scopus 로고    scopus 로고
    • Progesterone and its metabolite allopregnanolone decrease the expression of inflammatory cytokines after traumatic brain injury
    • He J., Hoffman S.W., Evens C.-O., Simkins R.M., Oyesiku N.M., Stein D.G. Progesterone and its metabolite allopregnanolone decrease the expression of inflammatory cytokines after traumatic brain injury. J. Neurotrauma. 18:2001;1140.
    • (2001) J. Neurotrauma , vol.18 , pp. 1140
    • He, J.1    Hoffman, S.W.2    Evens, C.-O.3    Simkins, R.M.4    Oyesiku, N.M.5    Stein, D.G.6
  • 32
    • 0027999174 scopus 로고
    • Bilateral frontal cortical contusion in rats: Behavioral and anatomic consequences
    • Hoffman S.W., Fulop Z., Stein D.G. Bilateral frontal cortical contusion in rats: behavioral and anatomic consequences. J. Neurotrauma. 11:1994;417-431.
    • (1994) J. Neurotrauma , vol.11 , pp. 417-431
    • Hoffman, S.W.1    Fulop, Z.2    Stein, D.G.3
  • 33
    • 0028836969 scopus 로고
    • Intracerebral inflammatory response to experimental brain injury
    • Holmin S., Mathiesen T., Shetye J., Biberfeld P. Intracerebral inflammatory response to experimental brain injury. Acta Neurochir. 132:1995;110-119.
    • (1995) Acta Neurochir. , vol.132 , pp. 110-119
    • Holmin, S.1    Mathiesen, T.2    Shetye, J.3    Biberfeld, P.4
  • 34
    • 0030607198 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats
    • Jiang N., Chopp M., Stein D., Feit H. Progesterone is neuroprotective after transient middle cerebral artery occlusion in male rats. Brain Res. 735:1996;101-107.
    • (1996) Brain Res. , vol.735 , pp. 101-107
    • Jiang, N.1    Chopp, M.2    Stein, D.3    Feit, H.4
  • 35
    • 0028190331 scopus 로고
    • Neuron-glial interaction during injury and edema of the CNS
    • Kempski O.S., Volk C. Neuron-glial interaction during injury and edema of the CNS. Acta Neurochir. (Suppl). 60:1994;7-11.
    • (1994) Acta Neurochir. (Suppl) , vol.60 , pp. 7-11
    • Kempski, O.S.1    Volk, C.2
  • 37
    • 0022617742 scopus 로고
    • Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation
    • Kesslak J.P., Nieto-Sampedro M., Globus J., Cotman C.W. Transplants of purified astrocytes promote behavioral recovery after frontal cortex ablation. Exp. Neurol. 92:1986;377-390.
    • (1986) Exp. Neurol. , vol.92 , pp. 377-390
    • Kesslak, J.P.1    Nieto-Sampedro, M.2    Globus, J.3    Cotman, C.W.4
  • 38
    • 0029588463 scopus 로고
    • Current concepts of brain edema. Review of laboratory investigations
    • Kimelberg H.K. Current concepts of brain edema. Review of laboratory investigations. J. Neurosurg. 83:1995;1051-1059.
    • (1995) J. Neurosurg. , vol.83 , pp. 1051-1059
    • Kimelberg, H.K.1
  • 40
    • 0034016139 scopus 로고    scopus 로고
    • Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia
    • Kumon Y., Kim S.C., Tompkins P., Stevens A., Sakaki S., Loftus C.M. Neuroprotective effect of postischemic administration of progesterone in spontaneously hypertensive rats with focal cerebral ischemia. J. Neurosurg. 92:2000;848-852.
    • (2000) J. Neurosurg. , vol.92 , pp. 848-852
    • Kumon, Y.1    Kim, S.C.2    Tompkins, P.3    Stevens, A.4    Sakaki, S.5    Loftus, C.M.6
  • 41
    • 0034210539 scopus 로고    scopus 로고
    • Modulation of NADPH-diaphorase and glial fibrillary acidic protein by progesterone in astrocytes from normal and injured rat spinal cord
    • Labombarda F., Gonzalez S., Roig P., Lima A., Guennoun R., Schumacher M., De Nicola A.F. Modulation of NADPH-diaphorase and glial fibrillary acidic protein by progesterone in astrocytes from normal and injured rat spinal cord. J. Steroid Biochem. Mol. Biol. 73:2000;159-169.
    • (2000) J. Steroid Biochem. Mol. Biol. , vol.73 , pp. 159-169
    • Labombarda, F.1    Gonzalez, S.2    Roig, P.3    Lima, A.4    Guennoun, R.5    Schumacher, M.6    De Nicola, A.F.7
  • 42
    • 0025894721 scopus 로고
    • Nonspecific defence mechanism: The role of nitric oxide
    • Liew F.Y., Cox F.E. Nonspecific defence mechanism: the role of nitric oxide. Immunol. Today. 12:1991;A17-A21.
    • (1991) Immunol. Today , vol.12 , pp. 17-A21
    • Liew, F.Y.1    Cox, F.E.2
  • 43
    • 0025039606 scopus 로고
    • Inhibition of murine cytotoxic T cell responses by progesterone
    • Mannel D.N., Falk W., Yron I. Inhibition of murine cytotoxic T cell responses by progesterone. Immunol. Lett. 26:1990;89-94.
    • (1990) Immunol. Lett. , vol.26 , pp. 89-94
    • Mannel, D.N.1    Falk, W.2    Yron, I.3
  • 44
    • 0026323612 scopus 로고
    • Differential immunochemical markers reveal the normal distribution of brain macrophages and microglia in the developing rat brain
    • Milligan C.E., Cunningham T.J., Levitt P. Differential immunochemical markers reveal the normal distribution of brain macrophages and microglia in the developing rat brain. J. Comp. Neurol. 314:1991;125-135.
    • (1991) J. Comp. Neurol. , vol.314 , pp. 125-135
    • Milligan, C.E.1    Cunningham, T.J.2    Levitt, P.3
  • 45
    • 1842772395 scopus 로고    scopus 로고
    • Progesterone prevents ischemia-induced neuronal loss but not reactive gliosis in the caudate nucleus
    • Morali G., Gonzalez-Vidal M.D., Escobar A., Cervantes M. Progesterone prevents ischemia-induced neuronal loss but not reactive gliosis in the caudate nucleus. Abstr. Soc. Neurosci. 2002;392.10.
    • (2002) Abstr. Soc. Neurosci. , pp. 39210
    • Morali, G.1    Gonzalez-Vidal, M.D.2    Escobar, A.3    Cervantes, M.4
  • 46
    • 0034102549 scopus 로고    scopus 로고
    • Progesterone exacerbates striatal stroke injury in progesterone- deficient female animals
    • Murphy S.J., Traystman R.J., Hurn P.D., Duckles S.P. Progesterone exacerbates striatal stroke injury in progesterone-deficient female animals. Stroke. 31:2000;1173-1178.
    • (2000) Stroke , vol.31 , pp. 1173-1178
    • Murphy, S.J.1    Traystman, R.J.2    Hurn, P.D.3    Duckles, S.P.4
  • 47
    • 0023835065 scopus 로고
    • Early release of glia maturation factor and acidic fibroblast growth factor after rat brain injury
    • Nieto-Sampedro M., Lim R., Hicklin D.J., Cotman C.W. Early release of glia maturation factor and acidic fibroblast growth factor after rat brain injury. Neurosci. Lett. 86:1988;361-365.
    • (1988) Neurosci. Lett. , vol.86 , pp. 361-365
    • Nieto-Sampedro, M.1    Lim, R.2    Hicklin, D.J.3    Cotman, C.W.4
  • 50
    • 0025720505 scopus 로고
    • Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate
    • Piani D., Frei K., Do K.Q., Cuenod M., Fontana A. Murine brain macrophages induce NMDA receptor mediated neurotoxicity in vitro by secreting glutamate. Neurosci. Lett. 133:1991;159-162.
    • (1991) Neurosci. Lett. , vol.133 , pp. 159-162
    • Piani, D.1    Frei, K.2    Do, K.Q.3    Cuenod, M.4    Fontana, A.5
  • 52
    • 0032055288 scopus 로고    scopus 로고
    • Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation?
    • Ransohoff R.M., Tani M. Do chemokines mediate leukocyte recruitment in post-traumatic CNS inflammation? Trends Neurosci. 21:1998;154-159.
    • (1998) Trends Neurosci. , vol.21 , pp. 154-159
    • Ransohoff, R.M.1    Tani, M.2
  • 53
    • 0026690043 scopus 로고
    • Progesterone treatment attenuates brain edema following contusion injury in male and female rats
    • Roof R.L., Duvdevani R., Stein D.G. Progesterone treatment attenuates brain edema following contusion injury in male and female rats. Restor. Neurol. Neurosci. 4:1992;425-427.
    • (1992) Restor. Neurol. Neurosci. , vol.4 , pp. 425-427
    • Roof, R.L.1    Duvdevani, R.2    Stein, D.G.3
  • 54
    • 0028072396 scopus 로고
    • Progesterone facilitates cognitive recovery and reduces secondary neuronal loss caused by cortical contusion injury in male rats
    • Roof R.L., Duvdevani R., Braswell L., Stein D.G. Progesterone facilitates cognitive recovery and reduces secondary neuronal loss caused by cortical contusion injury in male rats. Exp. Neurol. 129:1994;64-69.
    • (1994) Exp. Neurol. , vol.129 , pp. 64-69
    • Roof, R.L.1    Duvdevani, R.2    Braswell, L.3    Stein, D.G.4
  • 55
    • 0030855406 scopus 로고    scopus 로고
    • Progesterone protects against lipid peroxidation following traumatic brain injury in rats
    • Roof R.L., Hoffman S.W., Stein D.G. Progesterone protects against lipid peroxidation following traumatic brain injury in rats. Mol. Chem. Neuropathol. 31:1997;1-11.
    • (1997) Mol. Chem. Neuropathol. , vol.31 , pp. 1-11
    • Roof, R.L.1    Hoffman, S.W.2    Stein, D.G.3
  • 56
    • 0033168727 scopus 로고    scopus 로고
    • Innate and adaptive immune responses can be beneficial for CNS repair
    • Schwartz M., Moalem G., Leibowitz-Amit R., Cohen I.R. Innate and adaptive immune responses can be beneficial for CNS repair. Trends Neurosci. 22:1999;295-299.
    • (1999) Trends Neurosci. , vol.22 , pp. 295-299
    • Schwartz, M.1    Moalem, G.2    Leibowitz-Amit, R.3    Cohen, I.R.4
  • 57
    • 0036444181 scopus 로고    scopus 로고
    • Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury
    • Shear D.A., Galani R., Hoffman S.W., Stein D.G. Progesterone protects against necrotic damage and behavioral abnormalities caused by traumatic brain injury. Exp. Neurol. 178:2002;59-67.
    • (2002) Exp. Neurol. , vol.178 , pp. 59-67
    • Shear, D.A.1    Galani, R.2    Hoffman, S.W.3    Stein, D.G.4
  • 58
    • 0026774797 scopus 로고
    • Induction of nitric oxide synthase in glial cells
    • Simmons M.L., Murphy S. Induction of nitric oxide synthase in glial cells. J. Neurochem. 59:1992;897-905.
    • (1992) J. Neurochem. , vol.59 , pp. 897-905
    • Simmons, M.L.1    Murphy, S.2
  • 59
    • 0008700587 scopus 로고    scopus 로고
    • The effect of Gacyclidine (a non-competitive NMDA receptor antagonist) treatment on edema formation following medial frontal cortex contusion injury in rats
    • Smith J.S., Darrell R.S., Osborne R.A., Reddy A., Fulop Z.L., Stein D.G. The effect of Gacyclidine (a non-competitive NMDA receptor antagonist) treatment on edema formation following medial frontal cortex contusion injury in rats. J. Neurotrauma. 15:1998;905.
    • (1998) J. Neurotrauma , vol.15 , pp. 905
    • Smith, J.S.1    Darrell, R.S.2    Osborne, R.A.3    Reddy, A.4    Fulop, Z.L.5    Stein, D.G.6
  • 60
    • 0034088103 scopus 로고    scopus 로고
    • Effects of the novel NMDA receptor antagonist gacyclidine on recovery from medial frontal cortex contusion injury in rats
    • Smith J.S., Fulop Z.L., Levinsohn S.A., Darrell R.S., Stein D.G. Effects of the novel NMDA receptor antagonist gacyclidine on recovery from medial frontal cortex contusion injury in rats. Neural Plast. 7:2000;73-91.
    • (2000) Neural Plast. , vol.7 , pp. 73-91
    • Smith, J.S.1    Fulop, Z.L.2    Levinsohn, S.A.3    Darrell, R.S.4    Stein, D.G.5
  • 62
    • 0033570133 scopus 로고    scopus 로고
    • Progesterone is neuroprotective after acute experimental spinal cord trauma in rats
    • Thomas A., Nockels R., Hiu P., Sharffrey C.I., Chopp M. Progesterone is neuroprotective after acute experimental spinal cord trauma in rats. Spine. 24:1999;2134-2138.
    • (1999) Spine , vol.24 , pp. 2134-2138
    • Thomas, A.1    Nockels, R.2    Hiu, P.3    Sharffrey, C.I.4    Chopp, M.5
  • 63
    • 0034850817 scopus 로고    scopus 로고
    • Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats
    • Wright D.W., Bauer M.E., Hoffman S.W., Stein D.G. Serum progesterone levels correlate with decreased cerebral edema after traumatic brain injury in male rats. J. Neurotrauma. 18:2001;901-909.
    • (2001) J. Neurotrauma , vol.18 , pp. 901-909
    • Wright, D.W.1    Bauer, M.E.2    Hoffman, S.W.3    Stein, D.G.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.