Serum biomarkers as predictors of long-term outcome in severe traumatic brain injury: Analysis from a randomized placebo-controlled Phase II clinical trial

Journal of Neurosurgery

Volumn 125, Issue 3, 2016, Pages 631-641

  Raheja, Amol ^a   Sinha, Sumit ^a   Samson, Neha ^a   Bhoi, Sanjeev ^a   Subramanian, Arulselvi ^a   Sharma, Pushpa ^b   Sharma, Bhawani Shankar ^a  

^a ALL INDIA INSTITUTE OF MEDICAL SCIENCES   (India)

^b UNIFORMED SERVICES UNIVERSITY OF THE HEALTH SCIENCES   (United States)

Author keywords

Glial fibrillary acidic protein; Interleukin 6; Predictors of outcome; Progesterone; Serum biomarkers; Severe traumatic brain injury; Trauma

Indexed keywords

BIOLOGICAL MARKER; ESTROGEN; GLIAL FIBRILLARY ACIDIC PROTEIN; INTERLEUKIN 6; NEURON SPECIFIC ENOLASE; PLACEBO; PROGESTERONE; PROTEIN S100B; TUMOR NECROSIS FACTOR;

ADULT; ARTICLE; DIAGNOSTIC ACCURACY; DIAGNOSTIC TEST ACCURACY STUDY; ENZYME LINKED IMMUNOSORBENT ASSAY; FEMALE; FUNCTIONAL INDEPENDENCE MEASURE; GLASGOW COMA SCALE; GLASGOW OUTCOME SCALE; HUMAN; INDUCED HYPOTHERMIA; MAJOR CLINICAL STUDY; MALE; OUTCOME ASSESSMENT; PHASE 2 CLINICAL TRIAL (TOPIC); PREDICTIVE VALUE; PRIORITY JOURNAL; PROTEIN BLOOD LEVEL; RANDOMIZED CONTROLLED TRIAL (TOPIC); RECEIVER OPERATING CHARACTERISTIC; SENSITIVITY AND SPECIFICITY; SEVERE TRAUMATIC BRAIN INJURY; SURVIVAL PREDICTION; TRAUMATIC BRAIN INJURY; ADOLESCENT; AGED; BLOOD; CLINICAL TRIAL; CONTROLLED STUDY; MIDDLE AGED; PHASE 2 CLINICAL TRIAL; PROGNOSIS; PROSPECTIVE STUDY; RANDOMIZED CONTROLLED TRIAL; SINGLE BLIND PROCEDURE; TIME FACTOR; YOUNG ADULT;

ADOLESCENT; ADULT; AGED; BIOMARKERS; BRAIN INJURIES, TRAUMATIC; FEMALE; GLASGOW OUTCOME SCALE; HUMANS; MALE; MIDDLE AGED; PROGNOSIS; PROSPECTIVE STUDIES; SINGLE-BLIND METHOD; TIME FACTORS; YOUNG ADULT;

EID: 84987653518     PISSN: 00223085     EISSN: 19330693     Source Type: Journal    
DOI: 10.3171/2015.6.JNS15674     Document Type: Article

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