The hayflick limit may determine the effective clonal diversity of Naive T Cells

Journal of Immunology

Volumn 196, Issue 12, 2016, Pages 4999-5004

  Ndifon, Wilfred ^a,b,c   Dushoff, Jonathan ^d  

^a AFRICAN INSTITUTE FOR MATHEMATICAL SCIENCES   (South Africa)

^b NATIONAL NUCLEAR RESEARCH INSTITUTE   (Ghana)

^c STELLENBOSCH UNIVERSITY   (South Africa)

^d MCMASTER UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ARTICLE; BIOACCUMULATION; CELL AGING; CELL CLONE; CELL LOSS; CELLULAR PARAMETERS; CLONAL CELL LINE; CLONAL VARIATION; CONTROLLED STUDY; DIPLOIDY; HAYFLICK LIMIT; HUMAN; HUMAN CELL; LYMPHOCYTE DIFFERENTIATION; LYMPHOCYTE PROLIFERATION; MATHEMATICAL ANALYSIS; PREDICTION; PRIORITY JOURNAL; STOCHASTIC MODEL; T LYMPHOCYTE; T LYMPHOCYTE SUBPOPULATION; ADULT; AGED; AGING; BIOLOGICAL MODEL; CD4+ T LYMPHOCYTE; CD8+ T LYMPHOCYTE; CELL DIVISION; CELL PROLIFERATION; COMPUTER SIMULATION; DNA REPLICATION; HOMEOSTASIS; IMMUNOLOGY; LYMPHOCYTE ACTIVATION; MARKOV CHAIN; MIDDLE AGED; PATHOLOGY; PHYSIOLOGY; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; AGING; CD4-POSITIVE T-LYMPHOCYTES; CD8-POSITIVE T-LYMPHOCYTES; CELL AGING; CELL DIVISION; CELL PROLIFERATION; CLONE CELLS; COMPUTER SIMULATION; DNA REPLICATION; HOMEOSTASIS; HUMANS; LYMPHOCYTE ACTIVATION; MIDDLE AGED; MODELS, BIOLOGICAL; STOCHASTIC PROCESSES; YOUNG ADULT;

EID: 84974815462     PISSN: 00221767     EISSN: 15506606     Source Type: Journal    
DOI: 10.4049/jimmunol.1502343     Document Type: Article

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