-
1
-
-
18844451820
-
Mediator and the mechanism of transcriptional activation
-
R.D. Kornberg Mediator and the mechanism of transcriptional activation Trends Biochem. Sci. 30 2005 235 239
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 235-239
-
-
Kornberg, R.D.1
-
2
-
-
84923811117
-
The Mediator complex: A central integrator of transcription
-
B.L. Allen, and D.J. Taatjes The Mediator complex: a central integrator of transcription Nat. Rev. Mol. Cell Biol. 16 2015 155 166
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 155-166
-
-
Allen, B.L.1
Taatjes, D.J.2
-
3
-
-
80455164640
-
Origins and activity of the Mediator complex
-
R.C. Conaway, and J.W. Conaway Origins and activity of the Mediator complex Semin. Cell Dev. Biol. 22 2011 729 734
-
(2011)
Semin. Cell Dev. Biol.
, vol.22
, pp. 729-734
-
-
Conaway, R.C.1
Conaway, J.W.2
-
4
-
-
77958111633
-
The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation
-
S. Malik, and R.G. Roeder The metazoan Mediator co-activator complex as an integrative hub for transcriptional regulation Nat. Rev. Genet. 11 2010 761 772
-
(2010)
Nat. Rev. Genet.
, vol.11
, pp. 761-772
-
-
Malik, S.1
Roeder, R.G.2
-
5
-
-
0034212441
-
Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells
-
S. Malik, and R.G. Roeder Transcriptional regulation through Mediator-like coactivators in yeast and metazoan cells Trends Biochem. Sci. 25 2000 277 283
-
(2000)
Trends Biochem. Sci.
, vol.25
, pp. 277-283
-
-
Malik, S.1
Roeder, R.G.2
-
6
-
-
0034507632
-
Transcription of eukaryotic protein-coding genes
-
T.I. Lee, and R.A. Young Transcription of eukaryotic protein-coding genes Annu. Rev. Genet. 34 2000 77 137
-
(2000)
Annu. Rev. Genet.
, vol.34
, pp. 77-137
-
-
Lee, T.I.1
Young, R.A.2
-
7
-
-
0033786937
-
Mediator of transcriptional regulation
-
L.C. Myers, and R.D. Kornberg Mediator of transcriptional regulation Annu. Rev. Biochem. 69 2000 729 749
-
(2000)
Annu. Rev. Biochem.
, vol.69
, pp. 729-749
-
-
Myers, L.C.1
Kornberg, R.D.2
-
8
-
-
84973139144
-
Mediator Architecture and RNA Polymerase II Interaction
-
C. Plaschka, K. Nozawa, and P. Cramer Mediator Architecture and RNA Polymerase II Interaction J. Mol. Biol. 428 2016 2569 2574
-
(2016)
J. Mol. Biol.
, vol.428
, pp. 2569-2574
-
-
Plaschka, C.1
Nozawa, K.2
Cramer, P.3
-
9
-
-
14544280757
-
Transcriptional regulation and the role of diverse coactivators in animal cells
-
R.G. Roeder Transcriptional regulation and the role of diverse coactivators in animal cells FEBS Lett. 579 2005 909 915
-
(2005)
FEBS Lett.
, vol.579
, pp. 909-915
-
-
Roeder, R.G.1
-
10
-
-
84923804845
-
Structural basis of transcription initiation by RNA polymerase II
-
S. Sainsbury, C. Bernecky, and P. Cramer Structural basis of transcription initiation by RNA polymerase II Nat. Rev. Mol. Cell Biol. 16 2015 129 143
-
(2015)
Nat. Rev. Mol. Cell Biol.
, vol.16
, pp. 129-143
-
-
Sainsbury, S.1
Bernecky, C.2
Cramer, P.3
-
11
-
-
84888130540
-
Structural insights into transcription initiation by RNA polymerase II
-
S. Grunberg, and S. Hahn Structural insights into transcription initiation by RNA polymerase II Trends Biochem. Sci. 38 2013 603 611
-
(2013)
Trends Biochem. Sci.
, vol.38
, pp. 603-611
-
-
Grunberg, S.1
Hahn, S.2
-
12
-
-
18844385514
-
Structure of eukaryotic Mediator complexes
-
J.Z. Chadick, and F.J. Asturias Structure of eukaryotic Mediator complexes Trends Biochem. Sci. 30 2005 264 271
-
(2005)
Trends Biochem. Sci.
, vol.30
, pp. 264-271
-
-
Chadick, J.Z.1
Asturias, F.J.2
-
13
-
-
77957139539
-
Mediator and cohesin connect gene expression and chromatin architecture
-
M.H. Kagey, J.J. Newman, S. Bilodeau, Y. Zhan, D.A. Orlando, N.L. van Berkum, and et al. Mediator and cohesin connect gene expression and chromatin architecture Nature. 467 2010 430 435
-
(2010)
Nature.
, vol.467
, pp. 430-435
-
-
Kagey, M.H.1
Newman, J.J.2
Bilodeau, S.3
Zhan, Y.4
Orlando, D.A.5
Van Berkum, N.L.6
-
14
-
-
84874368349
-
Activating RNAs associate with mediator to enhance chromatin architecture and transcription
-
F. Lai, U.A. Orom, M. Cesaroni, M. Beringer, D.J. Taatjes, G.A. Blobel, and R. Shiekhattar Activating RNAs associate with mediator to enhance chromatin architecture and transcription Nature. 494 2013 497 501
-
(2013)
Nature.
, vol.494
, pp. 497-501
-
-
Lai, F.1
Orom, U.A.2
Cesaroni, M.3
Beringer, M.4
Taatjes, D.J.5
Blobel, G.A.6
Shiekhattar, R.7
-
15
-
-
84868094446
-
Structure of the mediator head module bound to the carboxy-terminal domain of RNA polymerase II
-
P.J. Robinson, D.A. Bushnell, M.J. Trnka, A.L. Burlingame, and R.D. Kornberg Structure of the mediator head module bound to the carboxy-terminal domain of RNA polymerase II Proc. Natl. Acad. Sci. U. S. A. 109 2012 17,931 17,935
-
(2012)
Proc. Natl. Acad. Sci. U. S. A.
, vol.109
, pp. 17931-17935
-
-
Robinson, P.J.1
Bushnell, D.A.2
Trnka, M.J.3
Burlingame, A.L.4
Kornberg, R.D.5
-
16
-
-
84871456902
-
Structure of the Mediator head module
-
L. Lariviere, C. Plaschka, M. Seizl, L. Wenzeck, F. Kurth, and P. Cramer Structure of the Mediator head module Nature. 492 2012 448 451
-
(2012)
Nature.
, vol.492
, pp. 448-451
-
-
Lariviere, L.1
Plaschka, C.2
Seizl, M.3
Wenzeck, L.4
Kurth, F.5
Cramer, P.6
-
17
-
-
79952803747
-
Direct interaction of RNA polymerase II and mediator required for transcription in vivo
-
J. Soutourina, S. Wydau, Y. Ambroise, C. Boschiero, and M. Werner Direct interaction of RNA polymerase II and mediator required for transcription in vivo Science. 331 2011 1451 1454
-
(2011)
Science.
, vol.331
, pp. 1451-1454
-
-
Soutourina, J.1
Wydau, S.2
Ambroise, Y.3
Boschiero, C.4
Werner, M.5
-
18
-
-
48349095490
-
Mediator-dependent recruitment of TFIIH modules in preinitiation complex
-
C. Esnault, Y. Ghavi-Helm, S. Brun, J. Soutourina, N. Van Berkum, C. Boschiero, and et al. Mediator-dependent recruitment of TFIIH modules in preinitiation complex Mol. Cell. 31 2008 337 346
-
(2008)
Mol. Cell.
, vol.31
, pp. 337-346
-
-
Esnault, C.1
Ghavi-Helm, Y.2
Brun, S.3
Soutourina, J.4
Van Berkum, N.5
Boschiero, C.6
-
19
-
-
47249134314
-
Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex
-
H.M. Bourbon Comparative genomics supports a deep evolutionary origin for the large, four-module transcriptional mediator complex Nucleic Acids Res. 36 2008 3993 4008
-
(2008)
Nucleic Acids Res.
, vol.36
, pp. 3993-4008
-
-
Bourbon, H.M.1
-
20
-
-
84923319299
-
Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit
-
M.A. Cevher, Y. Shi, D. Li, B.T. Chait, S. Malik, and R.G. Roeder Reconstitution of active human core Mediator complex reveals a critical role of the MED14 subunit Nat. Struct. Mol. Biol. 21 2014 1028 1034
-
(2014)
Nat. Struct. Mol. Biol.
, vol.21
, pp. 1028-1034
-
-
Cevher, M.A.1
Shi, Y.2
Li, D.3
Chait, B.T.4
Malik, S.5
Roeder, R.G.6
-
21
-
-
84902186552
-
Subunit architecture and functional modular rearrangements of the transcriptional mediator complex
-
K.L. Tsai, C. Tomomori-Sato, S. Sato, R.C. Conaway, J.W. Conaway, and F.J. Asturias Subunit architecture and functional modular rearrangements of the transcriptional mediator complex Cell. 157 2014 1430 1444
-
(2014)
Cell.
, vol.157
, pp. 1430-1444
-
-
Tsai, K.L.1
Tomomori-Sato, C.2
Sato, S.3
Conaway, R.C.4
Conaway, J.W.5
Asturias, F.J.6
-
23
-
-
84923358406
-
Architecture of the RNA polymerase II-Mediator core initiation complex
-
C. Plaschka, L. Lariviere, L. Wenzeck, M. Seizl, M. Hemann, D. Tegunov, and et al. Architecture of the RNA polymerase II-Mediator core initiation complex Nature. 518 2015 376 380
-
(2015)
Nature.
, vol.518
, pp. 376-380
-
-
Plaschka, C.1
Lariviere, L.2
Wenzeck, L.3
Seizl, M.4
Hemann, M.5
Tegunov, D.6
-
24
-
-
84903816704
-
Redefining the modular organization of the core Mediator complex
-
X. Wang, Q. Sun, Z. Ding, J. Ji, J. Wang, X. Kong, J. Yang, and G. Cai Redefining the modular organization of the core Mediator complex Cell Res. 24 2014 796 808
-
(2014)
Cell Res.
, vol.24
, pp. 796-808
-
-
Wang, X.1
Sun, Q.2
Ding, Z.3
Ji, J.4
Wang, J.5
Kong, X.6
Yang, J.7
Cai, G.8
-
25
-
-
84946593198
-
Molecular architecture of the yeast Mediator complex
-
P.J. Robinson, M.J. Trnka, R. Pellarin, C.H. Greenberg, D.A. Bushnell, R. Davis, and et al. Molecular architecture of the yeast Mediator complex Elife. 4 2015 e08719
-
(2015)
Elife.
, vol.4
-
-
Robinson, P.J.1
Trnka, M.J.2
Pellarin, R.3
Greenberg, C.H.4
Bushnell, D.A.5
Davis, R.6
-
26
-
-
14844349559
-
Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator
-
S. Malik, H.J. Baek, W. Wu, and R.G. Roeder Structural and functional characterization of PC2 and RNA polymerase II-associated subpopulations of metazoan Mediator Mol. Cell. Biol. 25 2005 2117 2129
-
(2005)
Mol. Cell. Biol.
, vol.25
, pp. 2117-2129
-
-
Malik, S.1
Baek, H.J.2
Wu, W.3
Roeder, R.G.4
-
27
-
-
0035831475
-
Yeast nuclear extract contains two major forms of RNA polymerase II mediator complexes
-
Y. Liu, J.A. Ranish, R. Aebersold, and S. Hahn Yeast nuclear extract contains two major forms of RNA polymerase II mediator complexes J. Biol. Chem. 276 2001 7169 7175
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 7169-7175
-
-
Liu, Y.1
Ranish, J.A.2
Aebersold, R.3
Hahn, S.4
-
28
-
-
84875613843
-
Structural visualization of key steps in human transcription initiation
-
Y. He, J. Fang, D.J. Taatjes, and E. Nogales Structural visualization of key steps in human transcription initiation Nature. 495 2013 481 486
-
(2013)
Nature.
, vol.495
, pp. 481-486
-
-
He, Y.1
Fang, J.2
Taatjes, D.J.3
Nogales, E.4
-
29
-
-
84963971192
-
Zooming in on Transcription Preinitiation
-
(in this issue)
-
I. Berger Zooming in on Transcription Preinitiation J. Mol. Biol. 428 2016 2581 2591 (in this issue)
-
(2016)
J. Mol. Biol.
, vol.428
, pp. 2581-2591
-
-
Berger, I.1
-
30
-
-
0037694964
-
Assembly of a mediator/TFIID/TFIIA complex bypasses the need for an activator
-
K.M. Johnson, and M. Carey Assembly of a mediator/TFIID/TFIIA complex bypasses the need for an activator Curr. Biol. 13 2003 772 777
-
(2003)
Curr. Biol.
, vol.13
, pp. 772-777
-
-
Johnson, K.M.1
Carey, M.2
-
31
-
-
0036199506
-
Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s
-
H.J. Baek, S. Malik, J. Qin, and R.G. Roeder Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s Mol. Cell. Biol. 22 2002 2842 2852
-
(2002)
Mol. Cell. Biol.
, vol.22
, pp. 2842-2852
-
-
Baek, H.J.1
Malik, S.2
Qin, J.3
Roeder, R.G.4
-
32
-
-
79959939884
-
Human mediator subunit MED26 functions as a docking site for transcription elongation factors
-
H. Takahashi, T.J. Parmely, S. Sato, C. Tomomori-Sato, C.A. Banks, S.E. Kong, and et al. Human mediator subunit MED26 functions as a docking site for transcription elongation factors Cell. 146 2011 92 104
-
(2011)
Cell.
, vol.146
, pp. 92-104
-
-
Takahashi, H.1
Parmely, T.J.2
Sato, S.3
Tomomori-Sato, C.4
Banks, C.A.5
Kong, S.E.6
-
33
-
-
0033635048
-
Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action
-
M. Ito, C.X. Yuan, H.J. Okano, R.B. Darnell, and R.G. Roeder Involvement of the TRAP220 component of the TRAP/SMCC coactivator complex in embryonic development and thyroid hormone action Mol. Cell. 5 2000 683 693
-
(2000)
Mol. Cell.
, vol.5
, pp. 683-693
-
-
Ito, M.1
Yuan, C.X.2
Okano, H.J.3
Darnell, R.B.4
Roeder, R.G.5
-
34
-
-
0033567983
-
Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice
-
M. Tudor, P.J. Murray, C. Onufryk, R. Jaenisch, and R.A. Young Ubiquitous expression and embryonic requirement for RNA polymerase II coactivator subunit Srb7 in mice Genes Dev. 13 1999 2365 2368
-
(1999)
Genes Dev.
, vol.13
, pp. 2365-2368
-
-
Tudor, M.1
Murray, P.J.2
Onufryk, C.3
Jaenisch, R.4
Young, R.A.5
-
36
-
-
79953713243
-
Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly
-
C. Bernecky, P. Grob, C.C. Ebmeier, E. Nogales, and D.J. Taatjes Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly PLoS Biol. 9 2011 e1000603
-
(2011)
PLoS Biol.
, vol.9
-
-
Bernecky, C.1
Grob, P.2
Ebmeier, C.C.3
Nogales, E.4
Taatjes, D.J.5
-
37
-
-
61449143491
-
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
-
M.T. Knuesel, K.D. Meyer, C. Bernecky, and D.J. Taatjes The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function Genes Dev. 23 2009 439 451
-
(2009)
Genes Dev.
, vol.23
, pp. 439-451
-
-
Knuesel, M.T.1
Meyer, K.D.2
Bernecky, C.3
Taatjes, D.J.4
-
38
-
-
48349122949
-
Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation
-
N. Ding, H. Zhou, P.O. Esteve, H.G. Chin, S. Kim, X. Xu, and et al. Mediator links epigenetic silencing of neuronal gene expression with x-linked mental retardation Mol. Cell. 31 2008 347 359
-
(2008)
Mol. Cell.
, vol.31
, pp. 347-359
-
-
Ding, N.1
Zhou, H.2
Esteve, P.O.3
Chin, H.G.4
Kim, S.5
Xu, X.6
-
39
-
-
84876216563
-
Master transcription factors and mediator establish super-enhancers at key cell identity genes
-
W.A. Whyte, D.A. Orlando, D. Hnisz, B.J. Abraham, C.Y. Lin, M.H. Kagey, and et al. Master transcription factors and mediator establish super-enhancers at key cell identity genes Cell. 153 2013 307 319
-
(2013)
Cell.
, vol.153
, pp. 307-319
-
-
Whyte, W.A.1
Orlando, D.A.2
Hnisz, D.3
Abraham, B.J.4
Lin, C.Y.5
Kagey, M.H.6
-
40
-
-
84944257870
-
Mediator kinase inhibition further activates super-enhancer-associated genes in AML
-
H.E. Pelish, B.B. Liau, I.I. Nitulescu, A. Tangpeerachaikul, Z.C. Poss, D.H. Da Silva, and et al. Mediator kinase inhibition further activates super-enhancer-associated genes in AML Nature. 526 2015 273 276
-
(2015)
Nature.
, vol.526
, pp. 273-276
-
-
Pelish, H.E.1
Liau, B.B.2
Nitulescu, I.I.3
Tangpeerachaikul, A.4
Poss, Z.C.5
Da Silva, D.H.6
-
41
-
-
84959508384
-
The RNA Polymerase II CTD: The Increasing Complexity of a Low-Complexity Protein Domain
-
C. Jeronimo, P. Collin, and F. Robert The RNA Polymerase II CTD: The Increasing Complexity of a Low-Complexity Protein Domain J. Mol. Biol. 428 2016 2607 2622
-
(2016)
J. Mol. Biol.
, vol.428
, pp. 2607-2622
-
-
Jeronimo, C.1
Collin, P.2
Robert, F.3
-
42
-
-
58149163281
-
Malleable machines in transcription regulation: The mediator complex
-
A. Toth-Petroczy, C.J. Oldfield, I. Simon, Y. Takagi, A.K. Dunker, V.N. Uversky, and M. Fuxreiter Malleable machines in transcription regulation: the mediator complex PLoS Comput. Biol. 4 2008 e1000243
-
(2008)
PLoS Comput. Biol.
, vol.4
-
-
Toth-Petroczy, A.1
Oldfield, C.J.2
Simon, I.3
Takagi, Y.4
Dunker, A.K.5
Uversky, V.N.6
Fuxreiter, M.7
-
43
-
-
2942575993
-
A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology
-
S. Sato, C. Tomomori-Sato, T.J. Parmely, L. Florens, B. Zybailov, S.K. Swanson, and et al. A set of consensus mammalian mediator subunits identified by multidimensional protein identification technology Mol. Cell. 14 2004 685 691
-
(2004)
Mol. Cell.
, vol.14
, pp. 685-691
-
-
Sato, S.1
Tomomori-Sato, C.2
Parmely, T.J.3
Florens, L.4
Zybailov, B.5
Swanson, S.K.6
-
45
-
-
84959352865
-
Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction
-
J.L. Nishikawa, A. Boeszoermenyi, L.A. Vale-Silva, R. Torelli, B. Posteraro, Y.J. Sohn, and et al. Inhibiting fungal multidrug resistance by disrupting an activator-Mediator interaction Nature. 530 2016 485 489
-
(2016)
Nature.
, vol.530
, pp. 485-489
-
-
Nishikawa, J.L.1
Boeszoermenyi, A.2
Vale-Silva, L.A.3
Torelli, R.4
Posteraro, B.5
Sohn, Y.J.6
-
46
-
-
85027942059
-
A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction
-
K.L. Tsai, S. Sato, C. Tomomori-Sato, R.C. Conaway, J.W. Conaway, and F.J. Asturias A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction Nat. Struct. Mol. Biol. 20 2013 611 619
-
(2013)
Nat. Struct. Mol. Biol.
, vol.20
, pp. 611-619
-
-
Tsai, K.L.1
Sato, S.2
Tomomori-Sato, C.3
Conaway, R.C.4
Conaway, J.W.5
Asturias, F.J.6
-
47
-
-
0036645671
-
The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development
-
M. Ito, H.J. Okano, R.B. Darnell, and R.G. Roeder The TRAP100 component of the TRAP/Mediator complex is essential in broad transcriptional events and development EMBO J. 21 2002 3464 3475
-
(2002)
EMBO J.
, vol.21
, pp. 3464-3475
-
-
Ito, M.1
Okano, H.J.2
Darnell, R.B.3
Roeder, R.G.4
|