메뉴 건너뛰기




Volumn 20, Issue 5, 2013, Pages 611-619

A conserved Mediator-CDK8 kinase module association regulates Mediator-RNA polymerase II interaction

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 8; HOLOENZYME; RNA POLYMERASE II;

EID: 85027942059     PISSN: 15459993     EISSN: 15459985     Source Type: Journal    
DOI: 10.1038/nsmb.2549     Document Type: Article
Times cited : (172)

References (43)
  • 1
    • 33644852483 scopus 로고    scopus 로고
    • Mediator as a general transcription factor
    • Takagi, Y. & Kornberg, R.D. Mediator as a general transcription factor. J. Biol. Chem. 281, 80-89 (2006).
    • (2006) J. Biol. Chem. , vol.281 , pp. 80-89
    • Takagi, Y.1    Kornberg, R.D.2
  • 2
    • 0036199506 scopus 로고    scopus 로고
    • Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s
    • Baek, H.J., Malik, S., Qin, J. & Roeder, R.G. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Mol. Cell Biol. 22, 2842-2852 (2002).
    • (2002) Mol. Cell Biol. , vol.22 , pp. 2842-2852
    • Baek, H.J.1    Malik, S.2    Qin, J.3    Roeder, R.G.4
  • 3
    • 0025891809 scopus 로고
    • A mediator required for activation of RNA polymerase II transcription in vitro
    • Flanagan, P.M., Kelleher, R.J. III, Sayre, M.H., Tschochner, H. & Kornberg, R.D. A mediator required for activation of RNA polymerase II transcription in vitro. Nature 350, 436-438 (1991).
    • (1991) Nature , vol.350 , pp. 436-438
    • Flanagan, P.M.1    Kelleher Iii Sayre, J.R.M.H.2    Tschochner, H.3    Kornberg, R.D.4
  • 4
    • 0025316464 scopus 로고
    • Resolution of factors required for the initiation of transcription by yeast RNA polymerase II
    • Flanagan, P.M. et al. Resolution of factors required for the initiation of transcription by yeast RNA polymerase II. J. Biol. Chem. 265, 11105-11107 (1990).
    • (1990) J. Biol. Chem. , vol.265 , pp. 11105-11107
    • Flanagan, P.M.1
  • 5
    • 64049097892 scopus 로고    scopus 로고
    • Mediator structural conservation and implications for the regulation mechanism
    • Cai, G., Imasaki, T., Takagi, Y. & Asturias, F.J. Mediator structural conservation and implications for the regulation mechanism. Structure 17, 559-567 (2009).
    • (2009) Structure , vol.17 , pp. 559-567
    • Cai, G.1    Imasaki, T.2    Takagi, Y.3    Asturias, F.J.4
  • 6
    • 0032110627 scopus 로고    scopus 로고
    • Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases
    • Hengartner, C.J. et al. Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. Mol. Cell 2, 43-53 (1998).
    • (1998) Mol. Cell , vol.2 , pp. 43-53
    • Hengartner, C.J.1
  • 7
    • 0028937199 scopus 로고
    • A kinase-cyclin pair in the RNA polymerase II holoenzyme
    • Liao, S.M. et al. A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374, 193-196 (1995).
    • (1995) Nature , vol.374 , pp. 193-196
    • Liao, S.M.1
  • 8
    • 0024354605 scopus 로고
    • Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II
    • Nonet, M.L. & Young, R.A. Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics 123, 715-724 (1989).
    • (1989) Genetics , vol.123 , pp. 715-724
    • Nonet, M.L.1    Young, R.A.2
  • 9
    • 76349090199 scopus 로고    scopus 로고
    • CDK8 is a positive regulator of transcriptional elongation within the serum response network
    • Donner, A.J., Ebmeier, C.C., Taatjes, D.J. & Espinosa, J.M. CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nat. Struct. Mol. Biol. 17, 194-201 (2010).
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 194-201
    • Donner, A.J.1    Ebmeier, C.C.2    Taatjes, D.J.3    Espinosa, J.M.4
  • 10
    • 59249093974 scopus 로고    scopus 로고
    • The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator
    • Knuesel, M.T., Meyer, K.D., Donner, A.J., Espinosa, J.M. & Taatjes, D.J. The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator. Mol. Cell Biol. 29, 650-661 (2009).
    • (2009) Mol. Cell Biol. , vol.29 , pp. 650-661
    • Knuesel, M.T.1    Meyer, K.D.2    Donner, A.J.3    Espinosa, J.M.4    Taatjes, D.J.5
  • 11
    • 34250847654 scopus 로고    scopus 로고
    • CDK8 is a stimulus-specific positive coregulator of p53 target genes
    • Donner, A.J., Szostek, S., Hoover, J.M. & Espinosa, J.M. CDK8 is a stimulus-specific positive coregulator of p53 target genes. Mol. Cell 27, 121-133 (2007).
    • (2007) Mol. Cell , vol.27 , pp. 121-133
    • Donner, A.J.1    Szostek, S.2    Hoover, J.M.3    Espinosa, J.M.4
  • 12
    • 0037113938 scopus 로고    scopus 로고
    • A complex of the Srb8,-9,-10, and-11 transcriptional regulatory proteins from yeast
    • Borggrefe, T., Davis, R., Erdjument-Bromage, H., Tempst, P. & Kornberg, R.D. A complex of the Srb8,-9,-10, and-11 transcriptional regulatory proteins from yeast. J. Biol. Chem. 277, 44202-44207 (2002).
    • (2002) J. Biol. Chem. , vol.277 , pp. 44202-44207
    • Borggrefe, T.1    Davis, R.2    Erdjument-Bromage, H.3    Tempst, P.4    Kornberg, R.D.5
  • 13
    • 0028897907 scopus 로고
    • Association of an activator with an RNA polymerase II holoenzyme
    • Hengartner, C.J. et al. Association of an activator with an RNA polymerase II holoenzyme. Genes Dev. 9, 897-910 (1995).
    • (1995) Genes Dev. , vol.9 , pp. 897-910
    • Hengartner, C.J.1
  • 14
    • 0031881688 scopus 로고    scopus 로고
    • The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain
    • Myers, L.C. et al. The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev. 12, 45-54 (1998).
    • (1998) Genes Dev. , vol.12 , pp. 45-54
    • Myers, L.C.1
  • 15
    • 0346435096 scopus 로고    scopus 로고
    • Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro
    • Spahr, H. et al. Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro. J. Biol. Chem. 278, 51301-51306 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 51301-51306
    • Spahr, H.1
  • 16
    • 0037039776 scopus 로고    scopus 로고
    • Structure, function, and activator-induced conformations of the CRSP coactivator
    • Taatjes, D.J., Naar, A.M., Andel, F. III, Nogales, E. & Tjian, R. Structure, function, and activator-induced conformations of the CRSP coactivator. Science 295, 1058-1062 (2002).
    • (2002) Science , vol.295 , pp. 1058-1062
    • Taatjes, D.J.1    Naar, A.M.2    Andel Iii Nogales, F.E.3    Tjian, R.4
  • 17
    • 0032567081 scopus 로고    scopus 로고
    • Dissecting the regulatory circuitry of a eukaryotic genome
    • Holstege, F.C. et al. Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95, 717-728 (1998).
    • (1998) Cell , vol.95 , pp. 717-728
    • Holstege, F.C.1
  • 18
    • 61449143491 scopus 로고    scopus 로고
    • The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
    • Knuesel, M.T., Meyer, K.D., Bernecky, C. & Taatjes, D.J. The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function. Genes Dev. 23, 439-451 (2009).
    • (2009) Genes Dev. , vol.23 , pp. 439-451
    • Knuesel, M.T.1    Meyer, K.D.2    Bernecky, C.3    Taatjes, D.J.4
  • 19
    • 33750481873 scopus 로고    scopus 로고
    • The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II
    • Elmlund, H. et al. The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II. Proc. Natl. Acad. Sci. USA 103, 15788-15793 (2006).
    • (2006) Proc. Natl. Acad. Sci. USA , vol.103 , pp. 15788-15793
    • Elmlund, H.1
  • 20
    • 79953713243 scopus 로고    scopus 로고
    • Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly
    • Bernecky, C., Grob, P., Ebmeier, C.C., Nogales, E. & Taatjes, D.J. Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly. PLoS Biol. 9, e1000603 (2011).
    • (2011) PLoS Biol. , vol.9
    • Bernecky, C.1    Grob, P.2    Ebmeier, C.C.3    Nogales, E.4    Taatjes, D.J.5
  • 21
    • 0034841844 scopus 로고    scopus 로고
    • The tandem affinity purification (TAP) method: A general procedure of protein complex purification
    • Puig, O. et al. The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 24, 218-229 (2001).
    • (2001) Methods , vol.24 , pp. 218-229
    • Puig, O.1
  • 22
    • 84985231782 scopus 로고
    • Three-dimensional reconstruction from a single-exposure random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli
    • Radermacher, M., Wagenknecht, T., Verschoor, A. & Frank, J. Three-dimensional reconstruction from a single-exposure random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli. J. Microsc. 146, 113-136 (1987).
    • (1987) J. Microsc. , vol.146 , pp. 113-136
    • Radermacher, M.1    Wagenknecht, T.2    Verschoor, A.3    Frank, J.4
  • 23
    • 80052034056 scopus 로고    scopus 로고
    • The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder
    • Schneider, E.V. et al. The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder. J. Mol. Biol. 412, 251-266 (2011).
    • (2011) J. Mol. Biol. , vol.412 , pp. 251-266
    • Schneider, E.V.1
  • 24
    • 0035834772 scopus 로고    scopus 로고
    • The structural and functional organization of the yeast mediator complex
    • Kang, J.S. et al. The structural and functional organization of the yeast mediator complex. J. Biol. Chem. 276, 42003-42010 (2001).
    • (2001) J. Biol. Chem. , vol.276 , pp. 42003-42010
    • Kang, J.S.1
  • 25
    • 14344283020 scopus 로고    scopus 로고
    • Structural organization of yeast and mammalian mediator complexes
    • Dotson, M.R. et al. Structural organization of yeast and mammalian mediator complexes. Proc. Natl. Acad. Sci. USA 97, 14307-14310 (2000).
    • (2000) Proc. Natl. Acad. Sci. USA , vol.97 , pp. 14307-14310
    • Dotson, M.R.1
  • 26
    • 79960434142 scopus 로고    scopus 로고
    • Architecture of the Mediator head module
    • Imasaki, T. et al. Architecture of the Mediator head module. Nature 475, 240-243 (2011).
    • (2011) Nature , vol.475 , pp. 240-243
    • Imasaki, T.1
  • 28
    • 84871456902 scopus 로고    scopus 로고
    • Structure of the Mediator head module
    • Larivière, L. et al. Structure of the Mediator head module. Nature 492, 448-451 (2012).
    • (2012) Nature , vol.492 , pp. 448-451
    • Larivière, L.1
  • 29
    • 0036606879 scopus 로고    scopus 로고
    • Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation
    • Näär, A.M., Taatjes, D.J., Zhai, W., Nogales, E. & Tjian, R. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes Dev. 16, 1339-1344 (2002).
    • (2002) Genes Dev. , vol.16 , pp. 1339-1344
    • Näär, A.M.1    Taatjes, D.J.2    Zhai, W.3    Nogales, E.4    Tjian, R.5
  • 31
    • 0036671095 scopus 로고    scopus 로고
    • Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction
    • Davis, J.A., Takagi, Y., Kornberg, R.D. & Asturias, F.A. Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction. Mol. Cell 10, 409-415 (2002).
    • (2002) Mol. Cell , vol.10 , pp. 409-415
    • Davis, J.A.1    Takagi, Y.2    Kornberg, R.D.3    Asturias, F.A.4
  • 32
    • 84863011784 scopus 로고    scopus 로고
    • Iterative stable alignment and clustering of 2D transmission electron microscope images
    • Yang, Z., Fang, J., Chittuluru, J., Asturias, F.J. & Penczek, P.A. Iterative stable alignment and clustering of 2D transmission electron microscope images. Structure 20, 237-247 (2012).
    • (2012) Structure , vol.20 , pp. 237-247
    • Yang, Z.1    Fang, J.2    Chittuluru, J.3    Asturias, F.J.4    Penczek, P.A.5
  • 33
    • 84861082442 scopus 로고    scopus 로고
    • Interaction of the Mediator Head module with RNA Polymerase II
    • Cai, G. et al. Interaction of the Mediator Head module with RNA Polymerase II. Structure 20, 899-910 (2012).
    • (2012) Structure , vol.20 , pp. 899-910
    • Cai, G.1
  • 34
    • 0030947346 scopus 로고    scopus 로고
    • Evidence for a mediator cycle at the initiation of transcription
    • Svejstrup, J.Q. et al. Evidence for a mediator cycle at the initiation of transcription. Proc. Natl. Acad. Sci. USA 94, 6075-6078 (1997).
    • (1997) Proc. Natl. Acad. Sci. USA , vol.94 , pp. 6075-6078
    • Svejstrup, J.Q.1
  • 35
    • 80855133523 scopus 로고    scopus 로고
    • Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images
    • Penczek, P.A., Kimmel, M. & Spahn, C.M. Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images. Structure 19, 1582-1590 (2011).
    • (2011) Structure , vol.19 , pp. 1582-1590
    • Penczek, P.A.1    Kimmel, M.2    Spahn, C.M.3
  • 36
    • 59649102440 scopus 로고    scopus 로고
    • Conformational flexibility of metazoan fatty acid synthase enables catalysis
    • Brignole, E.J., Smith, S. & Asturias, F.J. Conformational flexibility of metazoan fatty acid synthase enables catalysis. Nat. Struct. Mol. Biol. 16, 190-197 (2009).
    • (2009) Nat. Struct. Mol. Biol. , vol.16 , pp. 190-197
    • Brignole, E.J.1    Smith, S.2    Asturias, F.J.3
  • 37
    • 77949266564 scopus 로고    scopus 로고
    • Mediator head module structure and functional interactions
    • Cai, G. et al. Mediator head module structure and functional interactions. Nat. Struct. Mol. Biol. 17, 273-279 (2010).
    • (2010) Nat. Struct. Mol. Biol. , vol.17 , pp. 273-279
    • Cai, G.1
  • 38
    • 0029975088 scopus 로고    scopus 로고
    • SPIDER and WEB: Processing and visualization of images in 3D electron microscopy and related fields
    • Frank, J. et al. SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J. Struct. Biol. 116, 190-199 (1996).
    • (1996) J. Struct. Biol. , vol.116 , pp. 190-199
    • Frank, J.1
  • 39
    • 33845296470 scopus 로고    scopus 로고
    • SPARX, a new environment for Cryo-EM image processing
    • Hohn, M. et al. SPARX, a new environment for Cryo-EM image processing. J. Struct. Biol. 157, 47-55 (2007).
    • (2007) J. Struct. Biol. , vol.157 , pp. 47-55
    • Hohn, M.1
  • 40
    • 63649113687 scopus 로고    scopus 로고
    • DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy
    • Voss, N.R., Yoshioka, C.K., Radermacher, M., Potter, C.S. & Carragher, B. DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy. J. Struct. Biol. 166, 205-213 (2009).
    • (2009) J. Struct. Biol. , vol.166 , pp. 205-213
    • Voss, N.R.1    Yoshioka, C.K.2    Radermacher, M.3    Potter, C.S.4    Carragher, B.5
  • 41
    • 4444221565 scopus 로고    scopus 로고
    • UCSF Chimera-A visualization system for exploratory research and analysis
    • Pettersen, E.F. et al. UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612 (2004).
    • (2004) J. Comput. Chem. , vol.25 , pp. 1605-1612
    • Pettersen, E.F.1
  • 42
    • 0038350988 scopus 로고    scopus 로고
    • Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3
    • Sato, S. et al. Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. J. Biol. Chem. 278, 15123-15127 (2003).
    • (2003) J. Biol. Chem. , vol.278 , pp. 15123-15127
    • Sato, S.1
  • 43
    • 0034046944 scopus 로고    scopus 로고
    • Plat-E: An efficient and stable system for transient packaging of retroviruses
    • Morita, S., Kojima, T. & Kitamura, T. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7, 1063-1066 (2000).
    • (2000) Gene Ther. , vol.7 , pp. 1063-1066
    • Morita, S.1    Kojima, T.2    Kitamura, T.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.