-
1
-
-
33644852483
-
Mediator as a general transcription factor
-
Takagi, Y. & Kornberg, R.D. Mediator as a general transcription factor. J. Biol. Chem. 281, 80-89 (2006).
-
(2006)
J. Biol. Chem.
, vol.281
, pp. 80-89
-
-
Takagi, Y.1
Kornberg, R.D.2
-
2
-
-
0036199506
-
Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s
-
Baek, H.J., Malik, S., Qin, J. & Roeder, R.G. Requirement of TRAP/mediator for both activator-independent and activator-dependent transcription in conjunction with TFIID-associated TAF(II)s. Mol. Cell Biol. 22, 2842-2852 (2002).
-
(2002)
Mol. Cell Biol.
, vol.22
, pp. 2842-2852
-
-
Baek, H.J.1
Malik, S.2
Qin, J.3
Roeder, R.G.4
-
3
-
-
0025891809
-
A mediator required for activation of RNA polymerase II transcription in vitro
-
Flanagan, P.M., Kelleher, R.J. III, Sayre, M.H., Tschochner, H. & Kornberg, R.D. A mediator required for activation of RNA polymerase II transcription in vitro. Nature 350, 436-438 (1991).
-
(1991)
Nature
, vol.350
, pp. 436-438
-
-
Flanagan, P.M.1
Kelleher Iii Sayre, J.R.M.H.2
Tschochner, H.3
Kornberg, R.D.4
-
4
-
-
0025316464
-
Resolution of factors required for the initiation of transcription by yeast RNA polymerase II
-
Flanagan, P.M. et al. Resolution of factors required for the initiation of transcription by yeast RNA polymerase II. J. Biol. Chem. 265, 11105-11107 (1990).
-
(1990)
J. Biol. Chem.
, vol.265
, pp. 11105-11107
-
-
Flanagan, P.M.1
-
5
-
-
64049097892
-
Mediator structural conservation and implications for the regulation mechanism
-
Cai, G., Imasaki, T., Takagi, Y. & Asturias, F.J. Mediator structural conservation and implications for the regulation mechanism. Structure 17, 559-567 (2009).
-
(2009)
Structure
, vol.17
, pp. 559-567
-
-
Cai, G.1
Imasaki, T.2
Takagi, Y.3
Asturias, F.J.4
-
6
-
-
0032110627
-
Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases
-
Hengartner, C.J. et al. Temporal regulation of RNA polymerase II by Srb10 and Kin28 cyclin-dependent kinases. Mol. Cell 2, 43-53 (1998).
-
(1998)
Mol. Cell
, vol.2
, pp. 43-53
-
-
Hengartner, C.J.1
-
7
-
-
0028937199
-
A kinase-cyclin pair in the RNA polymerase II holoenzyme
-
Liao, S.M. et al. A kinase-cyclin pair in the RNA polymerase II holoenzyme. Nature 374, 193-196 (1995).
-
(1995)
Nature
, vol.374
, pp. 193-196
-
-
Liao, S.M.1
-
8
-
-
0024354605
-
Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II
-
Nonet, M.L. & Young, R.A. Intragenic and extragenic suppressors of mutations in the heptapeptide repeat domain of Saccharomyces cerevisiae RNA polymerase II. Genetics 123, 715-724 (1989).
-
(1989)
Genetics
, vol.123
, pp. 715-724
-
-
Nonet, M.L.1
Young, R.A.2
-
9
-
-
76349090199
-
CDK8 is a positive regulator of transcriptional elongation within the serum response network
-
Donner, A.J., Ebmeier, C.C., Taatjes, D.J. & Espinosa, J.M. CDK8 is a positive regulator of transcriptional elongation within the serum response network. Nat. Struct. Mol. Biol. 17, 194-201 (2010).
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 194-201
-
-
Donner, A.J.1
Ebmeier, C.C.2
Taatjes, D.J.3
Espinosa, J.M.4
-
10
-
-
59249093974
-
The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator
-
Knuesel, M.T., Meyer, K.D., Donner, A.J., Espinosa, J.M. & Taatjes, D.J. The human CDK8 subcomplex is a histone kinase that requires Med12 for activity and can function independently of mediator. Mol. Cell Biol. 29, 650-661 (2009).
-
(2009)
Mol. Cell Biol.
, vol.29
, pp. 650-661
-
-
Knuesel, M.T.1
Meyer, K.D.2
Donner, A.J.3
Espinosa, J.M.4
Taatjes, D.J.5
-
11
-
-
34250847654
-
CDK8 is a stimulus-specific positive coregulator of p53 target genes
-
Donner, A.J., Szostek, S., Hoover, J.M. & Espinosa, J.M. CDK8 is a stimulus-specific positive coregulator of p53 target genes. Mol. Cell 27, 121-133 (2007).
-
(2007)
Mol. Cell
, vol.27
, pp. 121-133
-
-
Donner, A.J.1
Szostek, S.2
Hoover, J.M.3
Espinosa, J.M.4
-
12
-
-
0037113938
-
A complex of the Srb8,-9,-10, and-11 transcriptional regulatory proteins from yeast
-
Borggrefe, T., Davis, R., Erdjument-Bromage, H., Tempst, P. & Kornberg, R.D. A complex of the Srb8,-9,-10, and-11 transcriptional regulatory proteins from yeast. J. Biol. Chem. 277, 44202-44207 (2002).
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 44202-44207
-
-
Borggrefe, T.1
Davis, R.2
Erdjument-Bromage, H.3
Tempst, P.4
Kornberg, R.D.5
-
13
-
-
0028897907
-
Association of an activator with an RNA polymerase II holoenzyme
-
Hengartner, C.J. et al. Association of an activator with an RNA polymerase II holoenzyme. Genes Dev. 9, 897-910 (1995).
-
(1995)
Genes Dev.
, vol.9
, pp. 897-910
-
-
Hengartner, C.J.1
-
14
-
-
0031881688
-
The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain
-
Myers, L.C. et al. The Med proteins of yeast and their function through the RNA polymerase II carboxy-terminal domain. Genes Dev. 12, 45-54 (1998).
-
(1998)
Genes Dev.
, vol.12
, pp. 45-54
-
-
Myers, L.C.1
-
15
-
-
0346435096
-
Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro
-
Spahr, H. et al. Mediator influences Schizosaccharomyces pombe RNA polymerase II-dependent transcription in vitro. J. Biol. Chem. 278, 51301-51306 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 51301-51306
-
-
Spahr, H.1
-
16
-
-
0037039776
-
Structure, function, and activator-induced conformations of the CRSP coactivator
-
Taatjes, D.J., Naar, A.M., Andel, F. III, Nogales, E. & Tjian, R. Structure, function, and activator-induced conformations of the CRSP coactivator. Science 295, 1058-1062 (2002).
-
(2002)
Science
, vol.295
, pp. 1058-1062
-
-
Taatjes, D.J.1
Naar, A.M.2
Andel Iii Nogales, F.E.3
Tjian, R.4
-
17
-
-
0032567081
-
Dissecting the regulatory circuitry of a eukaryotic genome
-
Holstege, F.C. et al. Dissecting the regulatory circuitry of a eukaryotic genome. Cell 95, 717-728 (1998).
-
(1998)
Cell
, vol.95
, pp. 717-728
-
-
Holstege, F.C.1
-
18
-
-
61449143491
-
The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function
-
Knuesel, M.T., Meyer, K.D., Bernecky, C. & Taatjes, D.J. The human CDK8 subcomplex is a molecular switch that controls Mediator coactivator function. Genes Dev. 23, 439-451 (2009).
-
(2009)
Genes Dev.
, vol.23
, pp. 439-451
-
-
Knuesel, M.T.1
Meyer, K.D.2
Bernecky, C.3
Taatjes, D.J.4
-
19
-
-
33750481873
-
The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II
-
Elmlund, H. et al. The cyclin-dependent kinase 8 module sterically blocks Mediator interactions with RNA polymerase II. Proc. Natl. Acad. Sci. USA 103, 15788-15793 (2006).
-
(2006)
Proc. Natl. Acad. Sci. USA
, vol.103
, pp. 15788-15793
-
-
Elmlund, H.1
-
20
-
-
79953713243
-
Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly
-
Bernecky, C., Grob, P., Ebmeier, C.C., Nogales, E. & Taatjes, D.J. Molecular architecture of the human Mediator-RNA polymerase II-TFIIF assembly. PLoS Biol. 9, e1000603 (2011).
-
(2011)
PLoS Biol.
, vol.9
-
-
Bernecky, C.1
Grob, P.2
Ebmeier, C.C.3
Nogales, E.4
Taatjes, D.J.5
-
21
-
-
0034841844
-
The tandem affinity purification (TAP) method: A general procedure of protein complex purification
-
Puig, O. et al. The tandem affinity purification (TAP) method: a general procedure of protein complex purification. Methods 24, 218-229 (2001).
-
(2001)
Methods
, vol.24
, pp. 218-229
-
-
Puig, O.1
-
22
-
-
84985231782
-
Three-dimensional reconstruction from a single-exposure random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli
-
Radermacher, M., Wagenknecht, T., Verschoor, A. & Frank, J. Three-dimensional reconstruction from a single-exposure random conical tilt series applied to the 50S ribosomal subunit of Escherichia coli. J. Microsc. 146, 113-136 (1987).
-
(1987)
J. Microsc.
, vol.146
, pp. 113-136
-
-
Radermacher, M.1
Wagenknecht, T.2
Verschoor, A.3
Frank, J.4
-
23
-
-
80052034056
-
The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder
-
Schneider, E.V. et al. The structure of CDK8/CycC implicates specificity in the CDK/cyclin family and reveals interaction with a deep pocket binder. J. Mol. Biol. 412, 251-266 (2011).
-
(2011)
J. Mol. Biol.
, vol.412
, pp. 251-266
-
-
Schneider, E.V.1
-
24
-
-
0035834772
-
The structural and functional organization of the yeast mediator complex
-
Kang, J.S. et al. The structural and functional organization of the yeast mediator complex. J. Biol. Chem. 276, 42003-42010 (2001).
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 42003-42010
-
-
Kang, J.S.1
-
25
-
-
14344283020
-
Structural organization of yeast and mammalian mediator complexes
-
Dotson, M.R. et al. Structural organization of yeast and mammalian mediator complexes. Proc. Natl. Acad. Sci. USA 97, 14307-14310 (2000).
-
(2000)
Proc. Natl. Acad. Sci. USA
, vol.97
, pp. 14307-14310
-
-
Dotson, M.R.1
-
26
-
-
79960434142
-
Architecture of the Mediator head module
-
Imasaki, T. et al. Architecture of the Mediator head module. Nature 475, 240-243 (2011).
-
(2011)
Nature
, vol.475
, pp. 240-243
-
-
Imasaki, T.1
-
27
-
-
84868094446
-
Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II
-
Robinson, P.J., Bushnell, D.A., Trnka, M.J., Burlingame, A.L. & Kornberg, R.D. Structure of the Mediator Head module bound to the carboxy-terminal domain of RNA polymerase II. Proc. Natl. Acad. Sci. USA 109, 17931-17935 (2012).
-
(2012)
Proc. Natl. Acad. Sci. USA
, vol.109
, pp. 17931-17935
-
-
Robinson, P.J.1
Bushnell, D.A.2
Trnka, M.J.3
Burlingame, A.L.4
Kornberg, R.D.5
-
28
-
-
84871456902
-
Structure of the Mediator head module
-
Larivière, L. et al. Structure of the Mediator head module. Nature 492, 448-451 (2012).
-
(2012)
Nature
, vol.492
, pp. 448-451
-
-
Larivière, L.1
-
29
-
-
0036606879
-
Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation
-
Näär, A.M., Taatjes, D.J., Zhai, W., Nogales, E. & Tjian, R. Human CRSP interacts with RNA polymerase II CTD and adopts a specific CTD-bound conformation. Genes Dev. 16, 1339-1344 (2002).
-
(2002)
Genes Dev.
, vol.16
, pp. 1339-1344
-
-
Näär, A.M.1
Taatjes, D.J.2
Zhai, W.3
Nogales, E.4
Tjian, R.5
-
30
-
-
0038832859
-
Conserved structures of mediator and RNA polymerase II holoenzyme
-
Asturias, F.J., Jiang, Y.W., Myers, L.C., Gustafsson, C.M. & Kornberg, R.D. Conserved structures of mediator and RNA polymerase II holoenzyme. Science 283, 985-987 (1999).
-
(1999)
Science
, vol.283
, pp. 985-987
-
-
Asturias, F.J.1
Jiang, Y.W.2
Myers, L.C.3
Gustafsson, C.M.4
Kornberg, R.D.5
-
31
-
-
0036671095
-
Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction
-
Davis, J.A., Takagi, Y., Kornberg, R.D. & Asturias, F.A. Structure of the yeast RNA polymerase II holoenzyme: Mediator conformation and polymerase interaction. Mol. Cell 10, 409-415 (2002).
-
(2002)
Mol. Cell
, vol.10
, pp. 409-415
-
-
Davis, J.A.1
Takagi, Y.2
Kornberg, R.D.3
Asturias, F.A.4
-
32
-
-
84863011784
-
Iterative stable alignment and clustering of 2D transmission electron microscope images
-
Yang, Z., Fang, J., Chittuluru, J., Asturias, F.J. & Penczek, P.A. Iterative stable alignment and clustering of 2D transmission electron microscope images. Structure 20, 237-247 (2012).
-
(2012)
Structure
, vol.20
, pp. 237-247
-
-
Yang, Z.1
Fang, J.2
Chittuluru, J.3
Asturias, F.J.4
Penczek, P.A.5
-
33
-
-
84861082442
-
Interaction of the Mediator Head module with RNA Polymerase II
-
Cai, G. et al. Interaction of the Mediator Head module with RNA Polymerase II. Structure 20, 899-910 (2012).
-
(2012)
Structure
, vol.20
, pp. 899-910
-
-
Cai, G.1
-
34
-
-
0030947346
-
Evidence for a mediator cycle at the initiation of transcription
-
Svejstrup, J.Q. et al. Evidence for a mediator cycle at the initiation of transcription. Proc. Natl. Acad. Sci. USA 94, 6075-6078 (1997).
-
(1997)
Proc. Natl. Acad. Sci. USA
, vol.94
, pp. 6075-6078
-
-
Svejstrup, J.Q.1
-
35
-
-
80855133523
-
Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images
-
Penczek, P.A., Kimmel, M. & Spahn, C.M. Identifying conformational states of macromolecules by eigen-analysis of resampled cryo-EM images. Structure 19, 1582-1590 (2011).
-
(2011)
Structure
, vol.19
, pp. 1582-1590
-
-
Penczek, P.A.1
Kimmel, M.2
Spahn, C.M.3
-
36
-
-
59649102440
-
Conformational flexibility of metazoan fatty acid synthase enables catalysis
-
Brignole, E.J., Smith, S. & Asturias, F.J. Conformational flexibility of metazoan fatty acid synthase enables catalysis. Nat. Struct. Mol. Biol. 16, 190-197 (2009).
-
(2009)
Nat. Struct. Mol. Biol.
, vol.16
, pp. 190-197
-
-
Brignole, E.J.1
Smith, S.2
Asturias, F.J.3
-
37
-
-
77949266564
-
Mediator head module structure and functional interactions
-
Cai, G. et al. Mediator head module structure and functional interactions. Nat. Struct. Mol. Biol. 17, 273-279 (2010).
-
(2010)
Nat. Struct. Mol. Biol.
, vol.17
, pp. 273-279
-
-
Cai, G.1
-
38
-
-
0029975088
-
SPIDER and WEB: Processing and visualization of images in 3D electron microscopy and related fields
-
Frank, J. et al. SPIDER and WEB: processing and visualization of images in 3D electron microscopy and related fields. J. Struct. Biol. 116, 190-199 (1996).
-
(1996)
J. Struct. Biol.
, vol.116
, pp. 190-199
-
-
Frank, J.1
-
39
-
-
33845296470
-
SPARX, a new environment for Cryo-EM image processing
-
Hohn, M. et al. SPARX, a new environment for Cryo-EM image processing. J. Struct. Biol. 157, 47-55 (2007).
-
(2007)
J. Struct. Biol.
, vol.157
, pp. 47-55
-
-
Hohn, M.1
-
40
-
-
63649113687
-
DoG Picker and TiltPicker: Software tools to facilitate particle selection in single particle electron microscopy
-
Voss, N.R., Yoshioka, C.K., Radermacher, M., Potter, C.S. & Carragher, B. DoG Picker and TiltPicker: software tools to facilitate particle selection in single particle electron microscopy. J. Struct. Biol. 166, 205-213 (2009).
-
(2009)
J. Struct. Biol.
, vol.166
, pp. 205-213
-
-
Voss, N.R.1
Yoshioka, C.K.2
Radermacher, M.3
Potter, C.S.4
Carragher, B.5
-
41
-
-
4444221565
-
UCSF Chimera-A visualization system for exploratory research and analysis
-
Pettersen, E.F. et al. UCSF Chimera-a visualization system for exploratory research and analysis. J. Comput. Chem. 25, 1605-1612 (2004).
-
(2004)
J. Comput. Chem.
, vol.25
, pp. 1605-1612
-
-
Pettersen, E.F.1
-
42
-
-
0038350988
-
Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3
-
Sato, S. et al. Identification of mammalian Mediator subunits with similarities to yeast Mediator subunits Srb5, Srb6, Med11, and Rox3. J. Biol. Chem. 278, 15123-15127 (2003).
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 15123-15127
-
-
Sato, S.1
-
43
-
-
0034046944
-
Plat-E: An efficient and stable system for transient packaging of retroviruses
-
Morita, S., Kojima, T. & Kitamura, T. Plat-E: an efficient and stable system for transient packaging of retroviruses. Gene Ther. 7, 1063-1066 (2000).
-
(2000)
Gene Ther.
, vol.7
, pp. 1063-1066
-
-
Morita, S.1
Kojima, T.2
Kitamura, T.3
|