Optimization of freeze-drying condition of amikacin solid lipid nanoparticles using D-optimal experimental design

Pharmaceutical Development and Technology

Volumn 17, Issue 2, 2012, Pages 187-194

  Varshosaz, Jaleh ^a   Ghaffari, Solmaz ^a   Khoshayand, Mohammad Reza ^b   Atyabi, Fatemeh ^b   Dehkordi, Abbas Jafarian ^a   Kobarfard, Farzad ^c  

^a ISFAHAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^b TEHRAN UNIVERSITY OF MEDICAL SCIENCES   (Iran)

^c SHAHID BEHESHTI UNIVERSITY OF MEDICAL SCIENCES   (Iran)

Author keywords

Cryoprotectant; D optimal; Freeze drying; Particle size; Stability

Indexed keywords

AMIKACIN; CHOLESTEROL; SOLID LIPID NANOPARTICLE;

ARTICLE; CHEMICAL INTERACTION; D OPTIMAL EXPERIMENTAL DESIGN; DIFFERENTIAL SCANNING CALORIMETRY; EXPERIMENTAL DESIGN; FREEZE DRYING; PARTICLE SIZE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SUSTAINED DRUG RELEASE; THERMOGRAPHY; ZETA POTENTIAL;

AMIKACIN; ANTI-BACTERIAL AGENTS; CHOLESTEROL; DRUG STABILITY; FREEZE DRYING; NANOPARTICLES; PARTICLE SIZE; SUCROSE;

EID: 84857423152     PISSN: 10837450     EISSN: 10979867     Source Type: Journal    
DOI: 10.3109/10837450.2010.529149     Document Type: Article

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