Enhancing mechanism of Labrasol on intestinal membrane permeability of the hydrophilic drug gentamicin sulfate

European Journal of Pharmaceutics and Biopharmaceutics

Volumn 64, Issue 1, 2006, Pages 82-91

  Koga, Kenjiro ^a   Kusawake, Yoichi ^b   Ito, Yukako ^b   Sugioka, Nobuyuki ^b   Shibata, Nobuhito ^c   Takada, Kanji ^b  

^a HOKURIKU UNIVERSITY   (Japan)

^b KYOTO PHARMACEUTICAL UNIVERSITY   (Japan)

^c DOSHISHA WOMEN'S COLLEGE OF LIBERAL ARTS   (Japan)

Author keywords

Caprylocaproyl macrogol glyceride; Fluorescence anisotropy; Intestinal absorption; Membrane lipid fluidity; Micelle shape

Indexed keywords

GENTAMICIN; LABRASOL; LIPOSOME; MEMBRANE LIPID;

ANIMAL EXPERIMENT; ANISOTROPY; AQUEOUS SOLUTION; ARTICLE; DRUG MECHANISM; DRUG PENETRATION; ELECTROPHYSIOLOGY; FLUORESCENCE; HYDROPHILICITY; ILEUM; INTESTINE MUCOSA PERMEABILITY; MALE; MEMBRANE FLUIDITY; MEMBRANE RESISTANCE; MICELLE; NONHUMAN; RAT;

ABSORPTION; ANIMALS; ANTI-BACTERIAL AGENTS; CELL MEMBRANE; CHEMISTRY, PHARMACEUTICAL; GENTAMICINS; INTESTINES; MALE; MICELLES; MICROSCOPY, FLUORESCENCE; MICROVILLI; ORGANIC CHEMICALS; PERMEABILITY; RATS; RATS, WISTAR; TECHNOLOGY, PHARMACEUTICAL;

EID: 33746541075     PISSN: 09396411     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.ejpb.2006.03.011     Document Type: Article

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