-
1
-
-
80051669175
-
Intramembrane Proteolysis in Regulated Protein Trafficking
-
Lemberg, M. K. Intramembrane Proteolysis in Regulated Protein Trafficking. Traffic 12, 1109-1118, doi: 10.1111/j.1600-0854.2011.01219.x (2011).
-
(2011)
Traffic
, vol.12
, pp. 1109-1118
-
-
Lemberg, M.K.1
-
2
-
-
84964312761
-
The rhomboid-like superfamily: Molecular mechanisms and biological roles
-
Freeman, M. The rhomboid-like superfamily: molecular mechanisms and biological roles. Annual review of cell and developmental biology 30, 235-254, doi: 10.1146/annurev-cellbio-100913-012944 (2014).
-
(2014)
Annual Review of Cell and Developmental Biology
, vol.30
, pp. 235-254
-
-
Freeman, M.1
-
3
-
-
0032774518
-
Rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development
-
Guichard, A. et al. rhomboid and Star interact synergistically to promote EGFR/MAPK signaling during Drosophila wing vein development. Development 126, 2663-2676 (1999).
-
(1999)
Development
, vol.126
, pp. 2663-2676
-
-
Guichard, A.1
-
4
-
-
0034234250
-
A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling
-
Wasserman, J. D., Urban, S. & Freeman, M. A family of rhomboid-like genes: Drosophila rhomboid-1 and roughoid/rhomboid-3 cooperate to activate EGF receptor signaling. Genes Dev. 14, 1651-1663 (2000).
-
(2000)
Genes Dev.
, vol.14
, pp. 1651-1663
-
-
Wasserman, J.D.1
Urban, S.2
Freeman, M.3
-
5
-
-
0035913906
-
Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila
-
Lee, J. R., Urban, S., Garvey, C. F. & Freeman, M. Regulated intracellular ligand transport and proteolysis control EGF signal activation in Drosophila. Cell 107, 161-171 (2001).
-
(2001)
Cell
, vol.107
, pp. 161-171
-
-
Lee, J.R.1
Urban, S.2
Garvey, C.F.3
Freeman, M.4
-
6
-
-
0025060344
-
N. Rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster
-
Bier, E., Jan, L. Y. & Jan, Y. N. rhomboid, a gene required for dorsoventral axis establishment and peripheral nervous system development in Drosophila melanogaster. Genes & development 4, 190-203 (1990).
-
(1990)
Genes & Development
, vol.4
, pp. 190-203
-
-
Bier, E.1
Jan, L.Y.2
Jan, Y.3
-
7
-
-
14044266249
-
EGF signal propagation during C. Elegans vulval development mediated by ROM-1 rhomboid
-
Dutt, A., Canevascini, S., Froehli-Hoier, E. & Hajnal, A. EGF signal propagation during C. elegans vulval development mediated by ROM-1 rhomboid. PLoS biology 2, e334, doi: 10.1371/journal.pbio.0020334 (2004).
-
(2004)
PLoS Biology
, vol.2
, pp. e334
-
-
Dutt, A.1
Canevascini, S.2
Froehli-Hoier, E.3
Hajnal, A.4
-
8
-
-
62649171270
-
The role of protease activity in ErbB biology
-
Blobel, C. P., Carpenter, G. & Freeman, M. The role of protease activity in ErbB biology. Experimental cell research 315, 671-682, doi: 10.1016/j.yexcr.2008.10.011 (2009).
-
(2009)
Experimental Cell Research
, vol.315
, pp. 671-682
-
-
Blobel, C.P.1
Carpenter, G.2
Freeman, M.3
-
9
-
-
79955526700
-
Mammalian EGF receptor activation by the rhomboid protease RHBDL2
-
Adrain, C. et al. Mammalian EGF receptor activation by the rhomboid protease RHBDL2. EMBO reports 12, 421-427, doi: 10.1038/embor.2011.50 (2011).
-
(2011)
EMBO Reports
, vol.12
, pp. 421-427
-
-
Adrain, C.1
-
10
-
-
0032515018
-
An essential role for ectodomain shedding in mammalian development
-
Peschon, J. J. et al. An essential role for ectodomain shedding in mammalian development. Science 282, 1281-1284 (1998).
-
(1998)
Science
, vol.282
, pp. 1281-1284
-
-
Peschon, J.J.1
-
11
-
-
84901247682
-
From wavy hair to naked proteins: The role of transforming growth factor alpha in health and disease
-
Singh, B. & Coffey, R. J. From wavy hair to naked proteins: the role of transforming growth factor alpha in health and disease. Seminars in cell & developmental biology 28, 12-21, doi: 10.1016/j.semcdb.2014.03.003 (2014).
-
(2014)
Seminars in Cell & Developmental Biology
, vol.28
, pp. 12-21
-
-
Singh, B.1
Coffey, R.J.2
-
12
-
-
0033599039
-
EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF
-
Prenzel, N. et al. EGF receptor transactivation by G-protein-coupled receptors requires metalloproteinase cleavage of proHB-EGF. Nature 402, 884-888, doi: 10.1038/47260 (1999).
-
(1999)
Nature
, vol.402
, pp. 884-888
-
-
Prenzel, N.1
-
13
-
-
6344226758
-
Metalloproteinase-dependent transforming growth factor-alpha release mediates neurotensin-stimulated MAP kinase activation in human colonic epithelial cells
-
Zhao, D. et al. Metalloproteinase-dependent transforming growth factor-alpha release mediates neurotensin-stimulated MAP kinase activation in human colonic epithelial cells. The Journal of biological chemistry 279, 43547-43554, doi: 10.1074/jbc. M401453200 (2004).
-
(2004)
The Journal of Biological Chemistry
, vol.279
, pp. 43547-43554
-
-
Zhao, D.1
-
14
-
-
23844557144
-
Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: A new therapeutic approach
-
Lautrette, A. et al. Angiotensin II and EGF receptor cross-talk in chronic kidney diseases: a new therapeutic approach. Nat. Med. 11, 867-874 (2005).
-
(2005)
Nat. Med.
, vol.11
, pp. 867-874
-
-
Lautrette, A.1
-
15
-
-
0027057566
-
Cleavage of membrane-anchored growth factors involves distinct protease activities regulated through common mechanisms
-
Pandiella, A., Bosenberg, M. W., Huang, E. J., Besmer, P. & Massague, J. Cleavage of membrane-anchored growth factors involves distinct protease activities regulated through common mechanisms. The Journal of biological chemistry 267, 24028-24033 (1992).
-
(1992)
The Journal of Biological Chemistry
, vol.267
, pp. 24028-24033
-
-
Pandiella, A.1
Bosenberg, M.W.2
Huang, E.J.3
Besmer, P.4
Massague, J.5
-
16
-
-
84940055416
-
Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway
-
Song, W. et al. Rhomboid domain containing 1 promotes colorectal cancer growth through activation of the EGFR signalling pathway. Nature communications 6, 8022, doi: 10.1038/ncomms9022 (2015).
-
(2015)
Nature Communications
, vol.6
, pp. 8022
-
-
Song, W.1
-
17
-
-
84865389259
-
Ubiquitin-dependent intramembrane rhomboid protease promotes ERAD of membrane proteins
-
Fleig, L. et al. Ubiquitin-Dependent Intramembrane Rhomboid Protease Promotes ERAD of Membrane Proteins. Molecular cell 47, 558-569, doi: 10.1016/j.molcel.2012.06.008 (2012).
-
(2012)
Molecular Cell
, vol.47
, pp. 558-569
-
-
Fleig, L.1
-
18
-
-
35948982252
-
Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases
-
Lemberg, M. K. & Freeman, M. Functional and evolutionary implications of enhanced genomic analysis of rhomboid intramembrane proteases. Genome research 17, 1634-1646 (2007).
-
(2007)
Genome Research
, vol.17
, pp. 1634-1646
-
-
Lemberg, M.K.1
Freeman, M.2
-
19
-
-
84862064898
-
Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis
-
Wan, C. et al. Exosome-related multi-pass transmembrane protein TSAP6 is a target of rhomboid protease RHBDD1-induced proteolysis. Plos one 7, e37452, doi: 10.1371/journal.pone.0037452 (2012).
-
(2012)
Plos One
, vol.7
, pp. e37452
-
-
Wan, C.1
-
20
-
-
84878791679
-
Rhomboid domain containing 1 inhibits cell apoptosis by upregulating AP-1 activity and its downstream target Bcl-3
-
Ren, X. et al. Rhomboid domain containing 1 inhibits cell apoptosis by upregulating AP-1 activity and its downstream target Bcl-3. FEBS letters 587, 1793-1798, doi: 10.1016/j.febslet.2013.04.033 (2013).
-
(2013)
FEBS Letters
, vol.587
, pp. 1793-1798
-
-
Ren, X.1
-
21
-
-
15844406752
-
Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors
-
Arribas, J. et al. Diverse cell surface protein ectodomains are shed by a system sensitive to metalloprotease inhibitors. The Journal of biological chemistry 271, 11376-11382 (1996).
-
(1996)
The Journal of Biological Chemistry
, vol.271
, pp. 11376-11382
-
-
Arribas, J.1
-
22
-
-
33846056925
-
Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx
-
Horiuchi, K. et al. Substrate selectivity of epidermal growth factor-receptor ligand sheddases and their regulation by phorbol esters and calcium influx. Molecular biology of the cell 18, 176-188 (2007).
-
(2007)
Molecular Biology of the Cell
, vol.18
, pp. 176-188
-
-
Horiuchi, K.1
-
23
-
-
79959888488
-
RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation
-
Lu, J. P., Wang, Y., Sliter, D. A., Pearce, M. M. & Wojcikiewicz, R. J. RNF170 protein, an endoplasmic reticulum membrane ubiquitin ligase, mediates inositol 1,4,5-trisphosphate receptor ubiquitination and degradation. The Journal of biological chemistry 286, 24426-24433, doi: 10.1074/jbc.M111.251983 (2011).
-
(2011)
The Journal of Biological Chemistry
, vol.286
, pp. 24426-24433
-
-
Lu, J.P.1
Wang, Y.2
Sliter, D.A.3
Pearce, M.M.4
Wojcikiewicz, R.J.5
-
24
-
-
79953269767
-
Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling
-
Zettl, M., Adrain, C., Strisovsky, K., Lastun, V. & Freeman, M. Rhomboid family pseudoproteases use the ER quality control machinery to regulate intercellular signaling. Cell 145, 79-91, doi: 10.1016/j.cell.2011.02.047 (2011).
-
(2011)
Cell
, vol.145
, pp. 79-91
-
-
Zettl, M.1
Adrain, C.2
Strisovsky, K.3
Lastun, V.4
Freeman, M.5
-
25
-
-
84919466648
-
The yeast ER-intramembrane protease Ypf1 refines nutrient sensing by regulating transporter abundance
-
Avci, D. et al. The Yeast ER-Intramembrane Protease Ypf1 Refines Nutrient Sensing by Regulating Transporter Abundance. Molecular cell 56, 630-640 (2014).
-
(2014)
Molecular Cell
, vol.56
, pp. 630-640
-
-
Avci, D.1
-
26
-
-
84942087481
-
Clipping or extracting: Two ways to membrane protein degradation
-
Avci, D. & Lemberg, M. K. Clipping or Extracting: Two Ways to Membrane Protein Degradation. Trends in cell biology 25, 611-622, doi: 10.1016/j.tcb.2015.07.003 (2015).
-
(2015)
Trends in Cell Biology
, vol.25
, pp. 611-622
-
-
Avci, D.1
Lemberg, M.K.2
-
27
-
-
0027071814
-
The cytoplasmic carboxy-terminal amino-acid specifies cleavage of membrane tgf-alpha into soluble growth-factor
-
Bosenberg, M. W., Pandiella, A. & Massague, J. The Cytoplasmic Carboxy-Terminal Amino-Acid Specifies Cleavage of Membrane Tgf-Alpha into Soluble Growth-Factor. Cell 71, 1157-1165, doi: 10.1016/S0092-8674(05)80064-9 (1992).
-
(1992)
Cell
, vol.71
, pp. 1157-1165
-
-
Bosenberg, M.W.1
Pandiella, A.2
Massague, J.3
-
28
-
-
1842332725
-
The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing
-
Briley, G. P., Hissong, M. A., Chiu, M. L. & Lee, D. C. The carboxyl-terminal valine residues of proTGF alpha are required for its efficient maturation and intracellular routing. Molecular biology of the cell 8, 1619-1631 (1997).
-
(1997)
Molecular Biology of the Cell
, vol.8
, pp. 1619-1631
-
-
Briley, G.P.1
Hissong, M.A.2
Chiu, M.L.3
Lee, D.C.4
-
29
-
-
72149124813
-
Sequence-specific intramembrane proteolysis: Identification of a recognition motif in rhomboid substrates
-
Strisovsky, K., Sharpe, H. J. & Freeman, M. Sequence-specific intramembrane proteolysis: identification of a recognition motif in rhomboid substrates. Molecular cell 36, 1048-1059, doi: 10.1016/j.molcel.2009.11.006 (2009).
-
(2009)
Molecular Cell
, vol.36
, pp. 1048-1059
-
-
Strisovsky, K.1
Sharpe, H.J.2
Freeman, M.3
-
30
-
-
0027238315
-
The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts
-
Neame, S. J. & Isacke, C. M. The cytoplasmic tail of CD44 is required for basolateral localization in epithelial MDCK cells but does not mediate association with the detergent-insoluble cytoskeleton of fibroblasts. The Journal of cell biology 121, 1299-1310 (1993).
-
(1993)
The Journal of Cell Biology
, vol.121
, pp. 1299-1310
-
-
Neame, S.J.1
Isacke, C.M.2
-
31
-
-
84904657288
-
Biogenesis and secretion of exosomes
-
Kowal, J., Tkach, M. & Thery, C. Biogenesis and secretion of exosomes. Current opinion in cell biology 29, 116-125, doi: 10.1016/j. ceb.2014.05.004 (2014).
-
(2014)
Current Opinion in Cell Biology
, vol.29
, pp. 116-125
-
-
Kowal, J.1
Tkach, M.2
Thery, C.3
-
32
-
-
31544437691
-
A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44
-
Stoeck, A. et al. A role for exosomes in the constitutive and stimulus-induced ectodomain cleavage of L1 and CD44. The Biochemical journal 393, 609-618, doi: 10.1042/BJ20051013 (2006).
-
(2006)
The Biochemical Journal
, vol.393
, pp. 609-618
-
-
Stoeck, A.1
-
33
-
-
79955652381
-
Amphiregulin exosomes increase cancer cell invasion
-
Higginbotham, J. N. et al. Amphiregulin exosomes increase cancer cell invasion. Current biology: CB 21, 779-786, doi: 10.1016/j. cub.2011.03.043 (2011).
-
(2011)
Current Biology: CB
, vol.21
, pp. 779-786
-
-
Higginbotham, J.N.1
-
34
-
-
43249109372
-
Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Current protocols in cell biology/editorial board Juan S
-
Thery, C., Amigorena, S., Raposo, G. & Clayton, A. Isolation and characterization of exosomes from cell culture supernatants and biological fluids. Current protocols in cell biology/editorial board, Juan S. Bonifacino Chapter 3, Unit 3 22, doi: 10.1002/0471143030.cb0322s30 (2006).
-
(2006)
Bonifacino Chapter 3 Unit
, vol.3
, pp. 22
-
-
Thery, C.1
Amigorena, S.2
Raposo, G.3
Clayton, A.4
-
35
-
-
84863205689
-
Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway
-
Simpson, J. C. et al. Genome-wide RNAi screening identifies human proteins with a regulatory function in the early secretory pathway. Nature cell biology 14, 764-774, doi: 10.1038/ncb2510 (2012).
-
(2012)
Nature Cell Biology
, vol.14
, pp. 764-774
-
-
Simpson, J.C.1
-
36
-
-
77953593628
-
MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening
-
Farhan, H. et al. MAPK signaling to the early secretory pathway revealed by kinase/phosphatase functional screening. The Journal of cell biology 189, 997-1011, doi: 10.1083/jcb.200912082 (2010).
-
(2010)
The Journal of Cell Biology
, vol.189
, pp. 997-1011
-
-
Farhan, H.1
-
37
-
-
78650845707
-
G protein-coupled receptors: Novel targets for drug discovery in cancer Nature reviews
-
Lappano, R. & Maggiolini, M. G protein-coupled receptors: novel targets for drug discovery in cancer. Nature reviews. Drug discovery 10, 47-60, doi: 10.1038/nrd3320 (2011).
-
(2011)
Drug Discovery
, vol.10
, pp. 47-60
-
-
Lappano, R.1
Maggiolini, M.2
-
38
-
-
78649889063
-
EGF receptor activation by GPCRs: An universal pathway reveals different versions
-
Liebmann, C. EGF receptor activation by GPCRs: an universal pathway reveals different versions. Molecular and cellular endocrinology 331, 222-231, doi: 10.1016/j.mce.2010.04.008 (2011).
-
(2011)
Molecular and Cellular Endocrinology
, vol.331
, pp. 222-231
-
-
Liebmann, C.1
-
39
-
-
0025250383
-
High-density functional gastrin releasing peptide receptors on primate cells
-
Heimbrook, D. C., Wallen, J. W., Balishin, N. L., Friedman, A. & Oliff, A. High-density functional gastrin releasing peptide receptors on primate cells. Journal of the National Cancer Institute 82, 402-407 (1990).
-
(1990)
Journal of the National Cancer Institute
, vol.82
, pp. 402-407
-
-
Heimbrook, D.C.1
Wallen, J.W.2
Balishin, N.L.3
Friedman, A.4
Oliff, A.5
-
40
-
-
0035913908
-
Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases
-
Urban, S., Lee, J. R. & Freeman, M. Drosophila rhomboid-1 defines a family of putative intramembrane serine proteases. Cell 107, 173-182 (2001).
-
(2001)
Cell
, vol.107
, pp. 173-182
-
-
Urban, S.1
Lee, J.R.2
Freeman, M.3
-
41
-
-
0031020635
-
Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death
-
Huang, D. C., Cory, S. & Strasser, A. Bcl-2, Bcl-XL and adenovirus protein E1B19kD are functionally equivalent in their ability to inhibit cell death. Oncogene 14, 405-414, doi: 10.1038/sj.onc.1200848 (1997).
-
(1997)
Oncogene
, vol.14
, pp. 405-414
-
-
Huang, D.C.1
Cory, S.2
Bcl, S.A.3
-
42
-
-
0038771224
-
Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain
-
1425-1134
-
Urban, S. & Freeman, M. Substrate specificity of rhomboid intramembrane proteases is governed by helix-breaking residues in the substrate transmembrane domain. Mol. Cell 11, 1425-1134 (2003).
-
(2003)
Mol. Cell
, vol.11
-
-
Urban, S.1
Freeman, M.2
-
43
-
-
1642422313
-
Intramembrane cleavage of ephrinB3 by the human rhomboid family protease
-
Pascall, J. C. & Brown, K. D. Intramembrane cleavage of ephrinB3 by the human rhomboid family protease, RHBDL2. Biochem. Biophys. Res. Commun. 317, 244-252 (2004).
-
(2004)
RHBDL2. Biochem. Biophys. Res. Commun.
, vol.317
, pp. 244-252
-
-
Pascall, J.C.1
Brown, K.D.2
-
44
-
-
33947178517
-
Rhomboid cleaves Star to regulate the levels of secreted Spitz
-
Tsruya, R. et al. Rhomboid cleaves Star to regulate the levels of secreted Spitz. EMBO J. 26, 1211-1220 (2007).
-
(2007)
EMBO J.
, vol.26
, pp. 1211-1220
-
-
Tsruya, R.1
-
45
-
-
84855822415
-
Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE
-
doi: 335/6065/225 [pii]10.1126/science.1214400
-
Adrain, C., Zettl, M., Christova, Y., Taylor, N. & Freeman, M. Tumor necrosis factor signaling requires iRhom2 to promote trafficking and activation of TACE. Science 335, 225-228, doi: 335/6065/225 [pii]10.1126/science.1214400 (2012).
-
(2012)
Science
, vol.335
, pp. 225-228
-
-
Adrain, C.1
Zettl, M.2
Christova, Y.3
Taylor, N.4
Freeman, M.5
-
46
-
-
84862909285
-
IRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS
-
McIlwain, D. R. et al. iRhom2 regulation of TACE controls TNF-mediated protection against Listeria and responses to LPS. Science 335, 229-232, doi: 10.1126/science.1214448 (2011).
-
(2011)
Science
, vol.335
, pp. 229-232
-
-
McIlwain, D.R.1
-
47
-
-
84885320661
-
Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation
-
Christova, Y., Adrain, C., Bambrough, P., Ibrahim, A. & Freeman, M. Mammalian iRhoms have distinct physiological functions including an essential role in TACE regulation. EMBO reports 14, 884-890, doi: 10.1038/embor.2013.128 (2013).
-
(2013)
EMBO Reports
, vol.14
, pp. 884-890
-
-
Christova, Y.1
Adrain, C.2
Bambrough, P.3
Ibrahim, A.4
Freeman, M.5
-
48
-
-
84929224114
-
IRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling
-
Li, X. et al. iRhoms 1 and 2 are essential upstream regulators of ADAM17-dependent EGFR signaling. Proceedings of the National Academy of Sciences of the United States of America 112, 6080-6085, doi: 10.1073/pnas.1505649112 (2015).
-
(2015)
Proceedings of the National Academy of Sciences of the United States of America
, vol.112
, pp. 6080-6085
-
-
Li, X.1
-
49
-
-
59649109249
-
Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells
-
Zou, H. et al. Human rhomboid family-1 gene RHBDF1 participates in GPCR-mediated transactivation of EGFR growth signals in head and neck squamous cancer cells. FASEB J 23, 425-432, doi: 10.1096/fj.08-112771 (2009).
-
(2009)
FASEB J
, vol.23
, pp. 425-432
-
-
Zou, H.1
-
50
-
-
84901266379
-
Human rhomboid family-1 suppresses oxygen-independent degradation of hypoxia-inducible factor-1alpha in breast cancer
-
Zhou, Z. et al. Human rhomboid family-1 suppresses oxygen-independent degradation of hypoxia-inducible factor-1alpha in breast cancer. Cancer research 74, 2719-2730, doi: 10.1158/0008-5472.CAN-13-1027 (2014).
-
(2014)
Cancer Research
, vol.74
, pp. 2719-2730
-
-
Zhou, Z.1
-
51
-
-
84962422620
-
Cytosolic extensions directly regulate a rhomboid protease by modulating substrate gating
-
Baker, R. P. & Urban, S. Cytosolic extensions directly regulate a rhomboid protease by modulating substrate gating. Nature 523, 101-105, doi: 10.1038/nature14357 (2015).
-
(2015)
Nature
, vol.523
, pp. 101-105
-
-
Baker, R.P.1
Urban, S.2
-
52
-
-
18344386695
-
SCF-mediated protein degradation and cell cycle control
-
Ang, X. L. & Wade Harper, J. SCF-mediated protein degradation and cell cycle control. Oncogene 24, 2860-2870, doi: 10.1038/sj.onc.1208614 (2005).
-
(2005)
Oncogene
, vol.24
, pp. 2860-2870
-
-
Ang, X.L.1
Wade Harper, J.2
-
53
-
-
0037416187
-
TACE is required for the activation of the EGFR by TGF-alpha in tumors
-
Borrell-Pages, M., Rojo, F., Albanell, J., Baselga, J. & Arribas, J. TACE is required for the activation of the EGFR by TGF-alpha in tumors. The EMBO journal 22, 1114-1124, doi: 10.1093/emboj/cdg111 (2003).
-
(2003)
The EMBO Journal
, vol.22
, pp. 1114-1124
-
-
Borrell-Pages, M.1
Rojo, F.2
Albanell, J.3
Baselga, J.4
Arribas, J.5
-
54
-
-
57149087260
-
Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes
-
Hakulinen, J., Sankkila, L., Sugiyama, N., Lehti, K. & Keski-Oja, J. Secretion of active membrane type 1 matrix metalloproteinase (MMP-14) into extracellular space in microvesicular exosomes. Journal of cellular biochemistry 105, 1211-1218, doi: 10.1002/jcb.21923 (2008).
-
(2008)
Journal of Cellular Biochemistry
, vol.105
, pp. 1211-1218
-
-
Hakulinen, J.1
Sankkila, L.2
Sugiyama, N.3
Lehti, K.4
Keski-Oja, J.5
-
55
-
-
33748324486
-
Sivelestat, a specific neutrophil elastase inhibitor, suppresses the growth of gastric carcinoma cells by preventing the release of transforming growth factor-alpha
-
Wada, Y. et al. Sivelestat, a specific neutrophil elastase inhibitor, suppresses the growth of gastric carcinoma cells by preventing the release of transforming growth factor-alpha. Cancer science 97, 1037-1043, doi: 10.1111/j.1349-7006.2006.00278.x (2006).
-
(2006)
Cancer Science
, vol.97
, pp. 1037-1043
-
-
Wada, Y.1
-
56
-
-
0032768970
-
CD44 cell adhesion molecules
-
Goodison, S., Urquidi, V. & Tarin, D. CD44 cell adhesion molecules. Molecular pathology: MP 52, 189-196 (1999).
-
(1999)
Molecular Pathology: MP
, vol.52
, pp. 189-196
-
-
Goodison, S.1
Urquidi, V.2
Tarin, D.3
-
57
-
-
1242288387
-
Diverse substrate recognition mechanisms for rhomboids; Thrombomodulin is cleaved by Mammalian rhomboids
-
Lohi, O., Urban, S. & Freeman, M. Diverse substrate recognition mechanisms for rhomboids; thrombomodulin is cleaved by Mammalian rhomboids. Curr. Biol. 14, 236-241 (2004).
-
(2004)
Curr. Biol.
, vol.14
, pp. 236-241
-
-
Lohi, O.1
Urban, S.2
Freeman, M.3
-
58
-
-
0024520745
-
Site-directed mutagenesis by overlap extension using the polymerase chain reaction
-
Ho, S. N., Hunt, H. D., Horton, R. M., Pullen, J. K. & Pease, L. R. Site-directed mutagenesis by overlap extension using the polymerase chain reaction. Gene 77, 51-59 (1989).
-
(1989)
Gene
, vol.77
, pp. 51-59
-
-
Ho, S.N.1
Hunt, H.D.2
Horton, R.M.3
Pullen, J.K.4
Pease, L.R.5
-
59
-
-
31944440900
-
Golgi inheritance in mammalian cells is mediated through endoplasmic reticulum export activities
-
Altan-Bonnet, N. et al. Golgi inheritance in mammalian cells is mediated through endoplasmic reticulum export activities. Molecular biology of the cell 17, 990-1005, doi: 10.1091/mbc.E05-02-0155 (2006).
-
(2006)
Molecular Biology of the Cell
, vol.17
, pp. 990-1005
-
-
Altan-Bonnet, N.1
-
60
-
-
33644859410
-
Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics
-
Delivani, P., Adrain, C., Taylor, R. C., Duriez, P. J. & Martin, S. J. Role for CED-9 and Egl-1 as regulators of mitochondrial fission and fusion dynamics. Molecular cell 21, 761-773, doi: 10.1016/j.molcel.2006.01.034 (2006).
-
(2006)
Molecular Cell
, vol.21
, pp. 761-773
-
-
Delivani, P.1
Adrain, C.2
Taylor, R.C.3
Duriez, P.J.4
Martin, S.J.5
-
61
-
-
0037082158
-
High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells
-
Durocher, Y., Perret, S. & Kamen, A. High-level and high-throughput recombinant protein production by transient transfection of suspension-growing human 293-EBNA1 cells. Nucleic acids research 30, E9 (2002).
-
(2002)
Nucleic Acids Research
, vol.30
, pp. E9
-
-
Durocher, Y.1
Perret, S.2
Kamen, A.3
-
62
-
-
79955667485
-
The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking
-
Meissner, C., Lorenz, H., Weihofen, A., Selkoe, D. J. & Lemberg, M. K. The mitochondrial intramembrane protease PARL cleaves human Pink1 to regulate Pink1 trafficking. J Neurochem 117, 856-867, doi: 10.1111/j.1471-4159.2011.07253.x (2011).
-
(2011)
J Neurochem
, vol.117
, pp. 856-867
-
-
Meissner, C.1
Lorenz, H.2
Weihofen, A.3
Selkoe, D.J.4
Lemberg, M.K.5
-
63
-
-
39749193861
-
A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins
-
Rothbauer, U. et al. A versatile nanotrap for biochemical and functional studies with fluorescent fusion proteins. Molecular & cellular proteomics: MCP 7, 282-289, doi: 10.1074/mcp.M700342-MCP200 (2008).
-
(2008)
Molecular & Cellular Proteomics: MCP
, vol.7
, pp. 282-289
-
-
Rothbauer, U.1
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